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المؤلفون: Salerno JA; Institute of Biomedical Sciences, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil.; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil., Torquato T; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil., Temerozo JR; National Institute for Science and Technology on Neuroimmunomodulation (INCT/NIM), Oswaldo Cruz Institute (IOC), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Brazil.; Laboratory on Thymus Research, Oswaldo Cruz Institute (IOC), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Brazil., Goto-Silva L; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil., Karmirian K; Institute of Biomedical Sciences, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil.; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil., Mendes MA; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil., Sacramento CQ; Immunopharmacology Laboratory, Oswaldo Cruz Institute (IOC), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Brazil.; National Institute for Science and Technology on Innovation in Diseases of Neglected Populations (INCT/IDPN), Center for Technological Development in Health (CDTS), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Brazil., Fintelman-Rodrigues N; Immunopharmacology Laboratory, Oswaldo Cruz Institute (IOC), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Brazil.; National Institute for Science and Technology on Innovation in Diseases of Neglected Populations (INCT/IDPN), Center for Technological Development in Health (CDTS), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Brazil., Souza LRQ; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil., Ornelas IM; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil., Veríssimo CP; Institute of Biomedical Sciences, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil., Aragão LGHS; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil., Vitória G; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil., Pedrosa CSG; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil., da Silva Gomes Dias S; Immunopharmacology Laboratory, Oswaldo Cruz Institute (IOC), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Brazil., Cardoso Soares V; Institute of Biomedical Sciences, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil.; Immunopharmacology Laboratory, Oswaldo Cruz Institute (IOC), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Brazil., Puig-Pijuan T; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil.; Carlos Chagas Filho Institute of Biophysics (IBCCF), Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil., Salazar V; Department of Systems and Computer Engineering, COPPE, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil., Dariolli R; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.; PluriCell Biotech, São Paulo, Brazil., Biagi D; PluriCell Biotech, São Paulo, Brazil., Furtado DR; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil., Barreto Chiarini L; Carlos Chagas Filho Institute of Biophysics (IBCCF), Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil., Borges HL; Institute of Biomedical Sciences, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil., Bozza PT; Immunopharmacology Laboratory, Oswaldo Cruz Institute (IOC), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Brazil., Zaluar P Guimarães M; Institute of Biomedical Sciences, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil.; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil., Souza TML; Immunopharmacology Laboratory, Oswaldo Cruz Institute (IOC), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Brazil.; National Institute for Science and Technology on Innovation in Diseases of Neglected Populations (INCT/IDPN), Center for Technological Development in Health (CDTS), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Brazil., Rehen SK; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil.; Department of Genetics, Institute of Biology, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.

المصدر: PeerJ [PeerJ] 2021 Dec 20; Vol. 9, pp. e12595. Date of Electronic Publication: 2021 Dec 20 (Print Publication: 2021).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: PeerJ Inc Country of Publication: United States NLM ID: 101603425 Publication Model: eCollection Cited Medium: Print ISSN: 2167-8359 (Print) Linking ISSN: 21678359 NLM ISO Abbreviation: PeerJ Subsets: PubMed not MEDLINE

المؤلفون: Aragão LGHS; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Rio de Janeiro, Brazil., Oliveira JT; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Rio de Janeiro, Brazil., Temerozo JR; Laboratory on Thymus Research, Oswaldo Cruz Institute (IOC), Rio de Janeiro, Rio de Janeiro, Brazil.; National Institute for Science and Technology on Innovation in Diseases of Neglected Populations (INCT/IDPN), Center for Technological Development in Health (CDTS), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Rio de Janeiro, Brazil., Mendes MA; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Rio de Janeiro, Brazil., Salerno JA; Institute of Biomedical Sciences, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Rio de Janeiro, Brazil., Pedrosa CSG; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Rio de Janeiro, Brazil., Puig-Pijuan T; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Rio de Janeiro, Brazil.; Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Rio de Janeiro, Brazil., Veríssimo CP; Institute of Biomedical Sciences, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Rio de Janeiro, Brazil., Ornelas IM; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Rio de Janeiro, Brazil., Torquato T; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Rio de Janeiro, Brazil., Vitória G; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Rio de Janeiro, Brazil., Sacramento CQ; National Institute for Science and Technology on Innovation in Diseases of Neglected Populations (INCT/IDPN), Center for Technological Development in Health (CDTS), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Rio de Janeiro, Brazil.; Laboratory of Immunopharmacology, Oswaldo Cruz Institute (IOC), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Rio de Janeiro, Brazil., Fintelman-Rodrigues N; National Institute for Science and Technology on Innovation in Diseases of Neglected Populations (INCT/IDPN), Center for Technological Development in Health (CDTS), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Rio de Janeiro, Brazil.; Laboratory of Immunopharmacology, Oswaldo Cruz Institute (IOC), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Rio de Janeiro, Brazil., da Silva Gomes Dias S; Laboratory of Immunopharmacology, Oswaldo Cruz Institute (IOC), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Rio de Janeiro, Brazil., Cardoso Soares V; Laboratory of Immunopharmacology, Oswaldo Cruz Institute (IOC), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Rio de Janeiro, Brazil.; Program of Immunology and Inflammation, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Rio de Janeiro, Brazil., Souza LRQ; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Rio de Janeiro, Brazil., Karmirian K; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Rio de Janeiro, Brazil.; Institute of Biomedical Sciences, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Rio de Janeiro, Brazil., Goto-Silva L; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Rio de Janeiro, Brazil., Biagi D; Pluricell Biotech, São Paulo, São Paulo, Brazil., Cruvinel EM; Pluricell Biotech, São Paulo, São Paulo, Brazil., Dariolli R; Pluricell Biotech, São Paulo, São Paulo, Brazil.; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States., Furtado DR; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Rio de Janeiro, Brazil., Bozza PT; Laboratory of Immunopharmacology, Oswaldo Cruz Institute (IOC), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Rio de Janeiro, Brazil., Borges HL; Institute of Biomedical Sciences, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Rio de Janeiro, Brazil., Souza TML; National Institute for Science and Technology on Innovation in Diseases of Neglected Populations (INCT/IDPN), Center for Technological Development in Health (CDTS), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Rio de Janeiro, Brazil.; Laboratory of Immunopharmacology, Oswaldo Cruz Institute (IOC), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Rio de Janeiro, Brazil., Guimarães MZP; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Rio de Janeiro, Brazil.; Institute of Biomedical Sciences, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Rio de Janeiro, Brazil., Rehen SK; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Rio de Janeiro, Brazil.; Department of Genetics, Institute of Biology, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Rio de Janeiro, Brazil.

المصدر: PeerJ [PeerJ] 2021 Oct 08; Vol. 9, pp. e12262. Date of Electronic Publication: 2021 Oct 08 (Print Publication: 2021).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: PeerJ Inc Country of Publication: United States NLM ID: 101603425 Publication Model: eCollection Cited Medium: Print ISSN: 2167-8359 (Print) Linking ISSN: 21678359 NLM ISO Abbreviation: PeerJ Subsets: PubMed not MEDLINE

المؤلفون: Fintelman-Rodrigues N; Laboratório de Imunofarmacologia, Instituto Oswaldo Cruz (IOC), Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, Rio de Janeiro, Brazil.; National Institute for Science and Technology on Innovation in Diseases of Neglected Populations (INCT/IDPN), Center for Technological Development in Health (CDTS), Fiocruz, Rio de Janeiro, Rio de Janeiro, Brazil., Sacramento CQ; Laboratório de Imunofarmacologia, Instituto Oswaldo Cruz (IOC), Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, Rio de Janeiro, Brazil.; National Institute for Science and Technology on Innovation in Diseases of Neglected Populations (INCT/IDPN), Center for Technological Development in Health (CDTS), Fiocruz, Rio de Janeiro, Rio de Janeiro, Brazil., Ribeiro Lima C; National Institute for Science and Technology on Innovation in Diseases of Neglected Populations (INCT/IDPN), Center for Technological Development in Health (CDTS), Fiocruz, Rio de Janeiro, Rio de Janeiro, Brazil., Souza da Silva F; Laboratório de Biologia Molecular e Doenças Endêmicas, IOC, Fiocruz, Rio de Janeiro, Rio de Janeiro, Brazil.; National Institute for Science and Technology on Innovation in Diseases of Neglected Populations (INCT/IDPN), Center for Technological Development in Health (CDTS), Fiocruz, Rio de Janeiro, Rio de Janeiro, Brazil., Ferreira AC; Laboratório de Imunofarmacologia, Instituto Oswaldo Cruz (IOC), Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, Rio de Janeiro, Brazil.; Universidade Iguaçu, Nova Iguaçu, Rio de Janeiro, Brazil.; National Institute for Science and Technology on Innovation in Diseases of Neglected Populations (INCT/IDPN), Center for Technological Development in Health (CDTS), Fiocruz, Rio de Janeiro, Rio de Janeiro, Brazil., Mattos M; Laboratório de Imunofarmacologia, Instituto Oswaldo Cruz (IOC), Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, Rio de Janeiro, Brazil.; National Institute for Science and Technology on Innovation in Diseases of Neglected Populations (INCT/IDPN), Center for Technological Development in Health (CDTS), Fiocruz, Rio de Janeiro, Rio de Janeiro, Brazil., de Freitas CS; Laboratório de Imunofarmacologia, Instituto Oswaldo Cruz (IOC), Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, Rio de Janeiro, Brazil.; National Institute for Science and Technology on Innovation in Diseases of Neglected Populations (INCT/IDPN), Center for Technological Development in Health (CDTS), Fiocruz, Rio de Janeiro, Rio de Janeiro, Brazil., Cardoso Soares V; Laboratório de Imunofarmacologia, Instituto Oswaldo Cruz (IOC), Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, Rio de Janeiro, Brazil., da Silva Gomes Dias S; Laboratório de Imunofarmacologia, Instituto Oswaldo Cruz (IOC), Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, Rio de Janeiro, Brazil., Temerozo JR; Laboratório de Pesquisas sobre o Timo, IOC, Fiocruz, Rio de Janeiro, Rio de Janeiro, Brazil.; National Institute for Science and Technology on Neuroimmunomodulation (INCT/NIM), IOC, Fiocruz, Rio de Janeiro, Rio de Janeiro, Brazil., Miranda MD; Laboratório de Vírus Respiratório e do Sarampo, IOC, Fiocruz, Rio de Janeiro, Rio de Janeiro, Brazil., Matos AR; Laboratório de Vírus Respiratório e do Sarampo, IOC, Fiocruz, Rio de Janeiro, Rio de Janeiro, Brazil., Bozza FA; Instituto Nacional de Infectologia Evandro Chagas, Fiocruz, Rio de Janeiro, Rio de Janeiro, Brazil.; Instituto D'or de Pesquisa e Ensino, Rio de Janeiro, Rio de Janeiro, Brazil., Carels N; National Institute for Science and Technology on Innovation in Diseases of Neglected Populations (INCT/IDPN), Center for Technological Development in Health (CDTS), Fiocruz, Rio de Janeiro, Rio de Janeiro, Brazil., Alves CR; Laboratório de Biologia Molecular e Doenças Endêmicas, IOC, Fiocruz, Rio de Janeiro, Rio de Janeiro, Brazil., Siqueira MM; Laboratório de Vírus Respiratório e do Sarampo, IOC, Fiocruz, Rio de Janeiro, Rio de Janeiro, Brazil., Bozza PT; Laboratório de Imunofarmacologia, Instituto Oswaldo Cruz (IOC), Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, Rio de Janeiro, Brazil., Souza TML; Laboratório de Imunofarmacologia, Instituto Oswaldo Cruz (IOC), Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, Rio de Janeiro, Brazil tmoreno@cdts.fiocruz.br.; National Institute for Science and Technology on Innovation in Diseases of Neglected Populations (INCT/IDPN), Center for Technological Development in Health (CDTS), Fiocruz, Rio de Janeiro, Rio de Janeiro, Brazil.

المصدر: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2020 Sep 21; Vol. 64 (10). Date of Electronic Publication: 2020 Sep 21 (Print Publication: 2020).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE

مواضيع طبية MeSH: Antiviral Agents/*pharmacology , Atazanavir Sulfate/*pharmacology , Betacoronavirus/*drug effects , Cytokines/*metabolism , Ritonavir/*pharmacology, Animals ; Atazanavir Sulfate/chemistry ; Betacoronavirus/pathogenicity ; Betacoronavirus/physiology ; COVID-19 ; Cell Death/drug effects ; Chlorocebus aethiops ; Coronavirus 3C Proteases ; Coronavirus Infections/drug therapy ; Coronavirus Infections/metabolism ; Coronavirus Infections/pathology ; Cysteine Endopeptidases/chemistry ; Cysteine Endopeptidases/metabolism ; Drug Therapy, Combination ; Humans ; Inflammation/metabolism ; Inflammation/virology ; Lopinavir/pharmacology ; Molecular Docking Simulation ; Monocytes/virology ; Pandemics ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/metabolism ; Pneumonia, Viral/pathology ; Protease Inhibitors/pharmacology ; SARS-CoV-2 ; Vero Cells ; Viral Nonstructural Proteins/antagonists & inhibitors ; Viral Nonstructural Proteins/chemistry ; Viral Nonstructural Proteins/metabolism ; Virus Replication/drug effects ; COVID-19 Drug Treatment