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1
المؤلفون: Marc L. Reitman, Cheng Guo, Theresa M. Kelly, Constantin Tamvakopoulos, Joseph M. Metzger, Tianying Jian, Howard Y. Chen, Arthur A. Patchett, Oksana C. Palyha, Alison M. Strack, Allan J. Goodman, Ravi P. Nargund, Peter H. Dobbelaar, Yanqing Kan, Mark Hadden, Larry Yet, Peter R. Guzzo, Qianping Peng, Linus S. Lin, Shuwen He, Lauren P. Shearman, Alan J. Henderson, Carina P. Tan, Sargent Bruce J, Xiao-Ming Guan, Scott D. Feighner, Iyassu K. Sebhat, Jie Pan, Jian Liu, Donald J. Marsh, Matthew J. Wyvratt, Andrew D. Howard, Megan Ruenz
المصدر: Bioorganic & Medicinal Chemistry Letters. 20:1913-1917
مصطلحات موضوعية: Agonist, medicine.drug_class, Clinical Biochemistry, Biological Availability, Pharmaceutical Science, Pharmacology, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, medicine, Animals, Humans, Potency, Structure–activity relationship, Molecular Biology, Biphenyl, Chemistry, Drug discovery, fungi, Organic Chemistry, Imidazoles, Rats, Bombesin receptor, Bioavailability, Receptors, Bombesin, Molecular Medicine, Bombesin Receptor Subtype-3
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2
المؤلفون: Aleksandr Petrov, Lihu Yang, Ralph T. Mosley, Carina P. Tan, George J. Eiermann, Joel P. Berger, Sanjeev Kumar, Peter T. Meinke, Eric Chang, Sander G. Mills, Nancy A. Thornberry, Cheng Tang, Monica Einstein, Eric Cline, Yun-Ping Zhou, Min Ge, Songnian Lin, Andrew D. Howard, Yue Feng, Changyou Zhou, Taro E. Akiyama, Gino Salituro
المصدر: Bioorganic & Medicinal Chemistry Letters. 20:1298-1301
مصطلحات موضوعية: Agonist, endocrine system, medicine.medical_specialty, medicine.drug_class, medicine.medical_treatment, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Receptors, G-Protein-Coupled, Mice, Structure-Activity Relationship, Pharmacokinetics, Oral administration, Internal medicine, Free fatty acid receptor 1, Diabetes mellitus, Drug Discovery, medicine, Animals, Molecular Biology, Pancreatic hormone, Mice, Knockout, Glucose tolerance test, medicine.diagnostic_test, Chemistry, Insulin, Organic Chemistry, medicine.disease, Endocrinology, Molecular Medicine, Thiazolidinediones, Protein Binding
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3
المؤلفون: Lihu Yang, Ralph T. Mosley, Peter T. Meinke, Yue Feng, Nancy A. Thornberry, Monica Einstein, Carina P. Tan, George J. Eiermann, Changyou Zhou, Sander G. Mills, Sanjeev Kumar, Songnian Lin, Andrew D. Howard, Joel P. Berger, Aleksandr Petrov, Yun Ping Zhou, Gino Salituro, Taro E. Akiyama
المصدر: Diabetes
مصطلحات موضوعية: Blood Glucose, Male, Agonist, endocrine system, medicine.medical_specialty, medicine.drug_class, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, CHO Cells, Inositol 1,4,5-Trisphosphate, Type 2 diabetes, Fatty Acids, Nonesterified, In Vitro Techniques, Biology, Cell Line, Diabetes Mellitus, Experimental, Receptors, G-Protein-Coupled, Islets of Langerhans, Mice, Cricetulus, Pregnancy, Cricetinae, Internal medicine, Free fatty acid receptor 1, Diabetes mellitus, Insulin Secretion, Internal Medicine, medicine, Animals, Humans, Insulin, Obesity, Rats, Wistar, Receptor, Pancreatic hormone, Mice, Knockout, geography, geography.geographical_feature_category, Fatty Acids, Islet, medicine.disease, Dietary Fats, Pharmacology and Therapeutics, Rats, Mice, Inbred C57BL, Endocrinology, Animals, Newborn, Female
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4
المؤلفون: Mark T. Goulet, Lex H.T. Van der Ploeg, Junying Wang, Scott D. Feighner, Jonathan R. Young, Oksana C. Palyha, Douglas J. MacNeil, Cherilyn Turner, Donna L. Hreniuk, Ronsar Eid, Andreas W. Sailer, Robert J. DeVita, Xinchun Tong, Danny Chaung, Myle Hoang, Lauren P. Shearman, Carina P. Tan, Peter Lin, Jie Pan, Sloan Stribling, Alison M. Strack, Andrew D. Howard, Ramon E. Camacho, Jinlong Jiang
المصدر: Bioorganic & Medicinal Chemistry Letters. 16:5270-5274
مصطلحات موضوعية: Male, Quinuclidines, Melanin-concentrating hormone, medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, Carboxamide, Binding, Competitive, Biochemistry, Chemical synthesis, Rats, Sprague-Dawley, Aminoquinoline, Eating, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Drug Discovery, medicine, Animals, Humans, Receptors, Somatostatin, Molecular Biology, Molecular Structure, Organic Chemistry, Quinoline, Antagonist, Stereoisomerism, In vitro, Rats, chemistry, Quinolines, Molecular Medicine, Biological Assay, Energy Metabolism, medicine.drug
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المؤلفون: Lex H.T. Van der Ploeg, Mark T. Goulet, Lehua Chang, Carina P. Tan, Donna L. Hreniuk, Andreas W. Sailer, Scott D. Feighner, Jinlong Jiang, Robert J. DeVita, Jie Pan, Peter Lin, Oksana C. Palyha, Douglas J. MacNeil, Nancy R. Morin, Myle Hoang, Andrew D. Howard
المصدر: Bioorganic & Medicinal Chemistry Letters. 16:5275-5279
مصطلحات موضوعية: Melanin-concentrating hormone, medicine.drug_class, Stereochemistry, High-throughput screening, Clinical Biochemistry, Drug Evaluation, Preclinical, Pharmaceutical Science, Carboxamide, In Vitro Techniques, Binding, Competitive, Biochemistry, Chemical synthesis, Cell Line, Structure-Activity Relationship, chemistry.chemical_compound, mental disorders, Drug Discovery, medicine, Humans, Receptors, Somatostatin, Receptor, Molecular Biology, Molecular Structure, Organic Chemistry, Antagonist, Stereoisomerism, Combinatorial chemistry, In vitro, chemistry, 4-Aminoquinoline, Aminoquinolines, Molecular Medicine
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المؤلفون: Christopher P. Austin, Doreen E. Cashen, Sheng-Shung Pong, Brian D. Spar, Brett Connolly, Tung Ming Fong, D. Euan MacIntyre, Carina P. Tan, Michael R. Tota, Ravi P. Nargund, R. S. L. Chang, Oksana C. Palyha, Constantin Tamvakopoulos, Deborah L. Drazen, Anthony G. DiLella, Jennifer E. Drisko, David J. Figueroa, Tanya MacNeil, Andreas W. Sailer, David H. Weinberg, Randy J. Nelson, Charles Rosenblum, Cathy R.-R.C. Huang, Rui Tang, Arthur A. Patchett, Xiao-Ming Guan, Hong Yu, George J. Christ, Andrew D. Howard, Lex H.T. Van der Ploeg, William J. Martin, Aurawan Vongs, Iyassu K. Sebhat, Ralph A. Stearns
المصدر: Proceedings of the National Academy of Sciences. 99:11381-11386
مصطلحات موضوعية: Male, Agonist, medicine.medical_specialty, DNA, Complementary, Intracranial Pressure, medicine.drug_class, Blood Pressure, In Vitro Techniques, Biology, Somatosensory system, Mice, Sexual Behavior, Animal, Nerve Fibers, Internal medicine, Copulation, medicine, Animals, Glans, In Situ Hybridization, DNA Primers, Multidisciplinary, Reverse Transcriptase Polymerase Chain Reaction, Human penis, Feeding Behavior, Ribonuclease, Pancreatic, Biological Sciences, Spinal cord, Electric Stimulation, Mice, Inbred C57BL, Melanocortin 4 receptor, medicine.anatomical_structure, Endocrinology, Receptors, Corticotropin, Models, Animal, Receptor, Melanocortin, Type 4, Brainstem, Energy Metabolism, Penis
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::341db11f0e12a0307d07e04176cd4aad
https://doi.org/10.1073/pnas.172378699 -
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المؤلفون: Zhizhen Zeng, Carina P. Tan, Qingyun Liu, Jie Pan, Christopher P. Austin, Takehiro Fukami, Andreas W. Sailer, Masaki Ihara, Scott D. Feighner, Makoto Ito, Nancy R. Morin, Sharon J. Sadowski, Alka Bansal, Hisashi Iwaasa, Terrence P. McDonald, Qingping Jiang, David J. Figueroa, Akio Kanatani, Andrew D. Howard, Akane Ishihara, Betty Ky, Lex H.T. Van der Ploeg, Hideki Sano, Masahiko Ito, Sheng Shung Pong, Douglas J. MacNeil, Donna L. Hreniuk
المصدر: Proceedings of the National Academy of Sciences. 98:7564-7569
مصطلحات موضوعية: Male, medicine.medical_specialty, Melanin-concentrating hormone, Chromosomes, Human, Pair 22, Molecular Sequence Data, Neuropeptide, CHO Cells, In situ hybridization, Biology, Transfection, Pertussis toxin, Energy homeostasis, Receptors, G-Protein-Coupled, Radioligand Assay, chemistry.chemical_compound, Cricetinae, Internal medicine, Chlorocebus aethiops, medicine, Animals, Humans, Amino Acid Sequence, Receptors, Pituitary Hormone, Northern blot, Receptor, In Situ Hybridization, Multidisciplinary, Base Sequence, Sequence Homology, Amino Acid, Cell Membrane, Brain, Chromosome Mapping, Biological Sciences, respiratory system, Recombinant Proteins, Melanin-concentrating hormone receptor, Oncorhynchus keta, Endocrinology, chemistry, Organ Specificity, Pituitary Gland, COS Cells, Female, Sequence Alignment, hormones, hormone substitutes, and hormone antagonists
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5e3f3aae52683bd88155974da1fc050
https://doi.org/10.1073/pnas.121170598 -
8
المؤلفون: Sheng-Shung Pong, Scott D. Feighner, Carina P. Tan, Alex R. T. Bailey, Reid J. Leonard, Karen K. McKee, Roy G. Smith, Andrew D. Howard, Oksana C. Palyha, Patrick R. Griffin
المصدر: Endocrine. 14:009-014
مصطلحات موضوعية: Agonist, Adenosine, Indoles, medicine.drug_class, Peptide Hormones, Endocrinology, Diabetes and Metabolism, Growth hormone secretagogue receptor, Tetrazoles, Receptors, Cell Surface, Biology, Growth Hormone-Releasing Hormone, Partial agonist, Genome, Cell Line, Receptors, G-Protein-Coupled, Endocrinology, medicine, Animals, Humans, Spiro Compounds, Genomic library, Cloning, Molecular, Receptors, Ghrelin, Receptor, Gene, Motilin, Genetics, Genomic Library, Molecular Structure, Sequence Homology, Amino Acid, Tissue Extracts, fungi, Benzazepines, Molecular biology, Ghrelin, Gene Expression Regulation, Peptides, Oligopeptides, hormones, hormone substitutes, and hormone antagonists
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المؤلفون: Sheng-Shung Pong, Mark Abramovitz, Andrew D. Howard, Rino Stocco, Ploeg, Raman K. Bakshi, Stacia Kargman, Carina P. Tan, Donna L. Hreniuk, Margaret A. Cascieri, David J. Figueroa, Ravi P. Nargund, Karen K. McKee, Jilly F. Evans, Scott D. Feighner, Lex H. T. Van Der, Christopher P. Austin, Oksana C. Palyha, Roy G. Smith, Douglas J. MacNeil, Arthur A. Patchett, Gary P. O'Neill
المصدر: Science. 284:2184-2188
مصطلحات موضوعية: Receptors, Neuropeptide, medicine.medical_specialty, Colon, G protein, Motilin receptor, Molecular Sequence Data, Thyroid Gland, Gastric motility, Peptide hormone, Biology, Ligands, Transfection, Cell Line, Receptors, Gastrointestinal Hormone, Motilin, GTP-Binding Proteins, Internal medicine, Heterotrimeric G protein, Intestine, Small, medicine, Humans, Amino Acid Sequence, Cloning, Molecular, Receptor, Antrum, In Situ Hybridization, Binding Sites, Multidisciplinary, Base Sequence, Chromosomes, Human, Pair 13, digestive, oral, and skin physiology, Chromosome Mapping, Erythromycin, Alternative Splicing, Endocrinology, Gastric Mucosa, Calcium, hormones, hormone substitutes, and hormone antagonists
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المؤلفون: Dennis C. Dean, Donna L. Hreniuk, Karen K. McKee, Carina P. Tan, Ravi P. Nargund, Lht Van der Ploeg, JR Tata, Kristine Prendergast, Andrew D. Howard, Scott D. Feighner, Arthur A. Patchett, Oksana C. Palyha, JW Woods, Roy G. Smith, D Underwood
المصدر: Molecular Endocrinology. 12:137-145
مصطلحات موضوعية: Agonist, medicine.medical_specialty, Growth-hormone-releasing hormone receptor, Swine, medicine.drug_class, Endocrinology, Diabetes and Metabolism, Molecular Sequence Data, Receptors, Cell Surface, Peptide, Biology, Non peptide, Receptors, G-Protein-Coupled, Endocrinology, GTP-Binding Proteins, Thyrotropin-releasing hormone receptor, Internal medicine, medicine, Animals, Humans, Amino Acid Sequence, Receptors, Ghrelin, Receptor, Molecular Biology, chemistry.chemical_classification, Human Growth Hormone, Human growth hormone, General Medicine, Ligand (biochemistry), Transmembrane protein, Rats, Transmembrane domain, Biochemistry, chemistry, Hormone receptor, Mutagenesis, Site-Directed, Secretagogue, Peptides, Binding domain
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56d56a687a83b3f530fe4e6240d6ee0c
https://doi.org/10.1210/mend.12.1.0051
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