المؤلفون: Ulf Neumann, Mike Ufer, Laura H Jacobson, Marie‐Laure Rouzade‐Dominguez, Gunilla Huledal, Carine Kolly, Rainer M Lüönd, Rainer Machauer, Siem J Veenstra, Konstanze Hurth, Heinrich Rueeger, Marina Tintelnot‐Blomley, Matthias Staufenbiel, Derya R Shimshek, Ludovic Perrot, Wilfried Frieauff, Valerie Dubost, Hilmar Schiller, Barbara Vogg, Karen Beltz, Alexandre Avrameas, Sandrine Kretz, Nicole Pezous, Jean‐Michel Rondeau, Nicolau Beckmann, Andreas Hartmann, Stefan Vormfelde, Olivier J David, Bruno Galli, Rita Ramos, Ana Graf, Cristina Lopez Lopez

المصدر: EMBO Molecular Medicine, Vol 10, Iss 11, Pp n/a-n/a (2018)

مصطلحات موضوعية: Alzheimer's disease, BACE‐1 inhibitor, drug discovery, prevention, β‐amyloid, Medicine (General), R5-920, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

URL الوصول: https://doaj.org/article/48fbf5e81f1a4f18ae40665093c63175

المؤلفون: Srikanth Neelakantham, Kerri A Schoedel, Kasra Shakeri-Nejad, Anne Gardin, Carine Kolly

المصدر: Psychopharmacology

مصطلحات موضوعية: Ozanimod, Sphingosine 1 Phosphate Receptor Modulators, medicine.medical_specialty, Multiple Sclerosis, medicine.medical_treatment, Physical dependence, Review, Siponimod, Abuse, chemistry.chemical_compound, Clinical, Sphingosine, medicine, media_common.cataloged_instance, Animals, Humans, S1P receptor modulator, European union, Psychiatry, Adverse effect, Dependence, media_common, Pharmacology, business.industry, Non-clinical, Fingolimod, Stimulant, chemistry, Ponesimod, medicine.symptom, Lysophospholipids, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e945f3f02b07f0b77af8d91b7fb0f37a
https://pubmed.ncbi.nlm.nih.gov/34773483

المؤلفون: Carine Kolly, Stefan Viktor Vormfelde, Eric Legangneux, Pierre Jordaan, Gilbert Lefèvre, Ulf Neumann, Nicole Pezous, Mike Ufer

المصدر: Clinical and Translational Science

مصطلحات موضوعية: Adult, Male, 030213 general clinical medicine, medicine.medical_specialty, Moxifloxacin, 030226 pharmacology & pharmacy, QT interval, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, QRS complex, Electrocardiography, Young Adult, 0302 clinical medicine, Clinical Trials, Phase II as Topic, Heart Rate, Internal medicine, Heart rate, Oxazines, Medicine, Aspartic Acid Endopeptidases, Humans, General Pharmacology, Toxicology and Pharmaceutics, Young adult, PR interval, Aged, Randomized Controlled Trials as Topic, Aged, 80 and over, Clinical Trials, Phase I as Topic, Dose-Response Relationship, Drug, business.industry, General Neuroscience, Research, General Medicine, Articles, Middle Aged, Confidence interval, Clinical trial, Dose–response relationship, Long QT Syndrome, Cardiology, Female, Amyloid Precursor Protein Secretases, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b8b71a9cc36020c791c26459fa899cf
https://pubmed.ncbi.nlm.nih.gov/32583957

المؤلفون: Robert Kreutzer, Nicolau Beckmann, Derya R. Shimshek, Wilfried Frieauff, Karine Bigot, Irena Brzak, Ulf Neumann, Carine Kolly, Arno Doelemeyer, Daniel Neddermann, Pierre Moulin, Laura H. Jacobson, Diethilde Theil, Matthias Staufenbiel, Ludovic Perrot, Stefan Zurbruegg

المصدر: Neurobiology of Aging. 45:50-60

مصطلحات موضوعية: 0301 basic medicine, Genetically modified mouse, Aging, Pathology, medicine.medical_specialty, Inhibitor, Time Factors, Neuroscience(all), Thiazines, Clinical Neurology, Mice, Transgenic, Cerebral amyloid angiopathy (CAA), Entire brain, Pathogenesis, Microhemorrhage, 03 medical and health sciences, 0302 clinical medicine, Imaging, Three-Dimensional, medicine, Amyloid precursor protein, Animals, BACE, Magnetic resonance imaging (MRI), Picolinic Acids, Cerebral Hemorrhage, Microbleeding, biology, medicine.diagnostic_test, business.industry, General Neuroscience, Disease progression, Brain, Magnetic resonance imaging, medicine.disease, Ageing, 030104 developmental biology, Beta-secretase 1, Diffusion Magnetic Resonance Imaging, Alzheimer's disease (AD), biology.protein, Disease Progression, Female, Neurology (clinical), Cerebral amyloid angiopathy, Geriatrics and Gerontology, business, APP23, 030217 neurology & neurosurgery, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c49e4699c7546d6b51faf1fca39dfe

المؤلفون: Valerie Dubost, Bruno Galli, Laura H. Jacobson, Alexandre Avrameas, Wilfried Frieauff, Marie-Laure Rouzade-Dominguez, Konstanze Hurth, Derya R. Shimshek, Ulf Neumann, Nicole Pezous, Ana Graf, Karen Beltz, Jean-Michel Rondeau, Hilmar Schiller, Heinrich Rueeger, Nicolau Beckmann, Siem Jacob Veenstra, Marina Tintelnot-Blomley, Rita Ramos, Sandrine Kretz, Mike Ufer, Rainer Machauer, Stefan Viktor Vormfelde, Cristina Lopez Lopez, Gunilla Huledal, Olivier J. David, Carine Kolly, Andreas Hartmann, Rainer Lüönd, Barbara Vogg, Matthias Staufenbiel, Ludovic Perrot

المصدر: EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 10, Iss 11, Pp n/a-n/a (2018)

مصطلحات موضوعية: 0301 basic medicine, Male, Medicine (General), Pharmacology, QH426-470, Cathepsin D, Translational Research, Biomedical, Amyloid beta-Protein Precursor, 0302 clinical medicine, Cerebrospinal fluid, prevention, Amyloid precursor protein, Aspartic Acid Endopeptidases, News & Views, Microglia, biology, Neurodegeneration, Brain, BACE‐1 inhibitor, Hominidae, Alzheimer's disease, medicine.anatomical_structure, Molecular Medicine, Female, Mice, Transgenic, drug discovery, 03 medical and health sciences, R5-920, Alzheimer Disease, mental disorders, Oxazines, medicine, Genetics, Dementia, Animals, Humans, Pharmacology & Drug Discovery, Cerebral Hemorrhage, Inflammation, business.industry, medicine.disease, Mice, Inbred C57BL, 030104 developmental biology, Astrocytes, biology.protein, Verubecestat, β‐amyloid, Amyloid Precursor Protein Secretases, business, Amyloid precursor protein secretase, 030217 neurology & neurosurgery, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01044e86b3672f81bb8e9b69d171d1be
https://pubmed.ncbi.nlm.nih.gov/30322841

المؤلفون: André Cordier, David Ledieu, Francois Pognan, Sarah B. Voytek, J. Andreas Mahl, Page Bouchard, Annabelle Heier, Marc Raccuglia, Salah-Dine Chibout, Maria Papoutsi, Diethilde Theil, Carine Kolly, Andreas Hartmann, Katie Kubek-Luck, Christian Trendelenburg, Natalie M. Claudio, Patrick J. Devine

المصدر: Archives of Toxicology

مصطلحات موضوعية: 0301 basic medicine, Male, Health, Toxicology and Mutagenesis, Hemangiosarcoma, Administration, Oral, Stimulation, Mice, Inbred Strains, Genotoxicity and Carcinogenicity, Pharmacology, Siponimod, Toxicology, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, Species Specificity, In vivo, Benzyl Compounds, Hemangiosarcoma (HSA), Animals, Humans, Rats, Wistar, Receptor, Toxicity Tests, Chronic, Mitosis, Cells, Cultured, Placental growth factor (PLGF2), Placenta Growth Factor, Chemistry, Cell growth, Endothelial Cells, General Medicine, In vitro, Toxicokinetics, Endothelial stem cell, Receptors, Lysosphingolipid, 030104 developmental biology, Azetidines, Sphingosine-1-phosphate Receptor 1 (S1P1), Endothelium, Vascular, Transcriptome, Vascular endothelial cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b80cfb9fc5b3106fc9755e4ddeae32e9
https://pubmed.ncbi.nlm.nih.gov/29556671

المؤلفون: Carine Kolly, Marie-Laure Rouzade-Dominguez, Gabriel Vargas, Cristina Lopez-Lopez, Ulf Neumann, Nicole Pezous, Mike Ufer, Olivier J. David, Robert A. Lenz, Ana Graf, Pierre N. Tariot, Eric M. Reiman

المصدر: Alzheimer's & Dementia. 13

مصطلحات موضوعية: Gerontology, medicine.medical_specialty, Epidemiology, business.industry, Health Policy, Alternative medicine, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Medicine, Medical physics, Neurology (clinical), Geriatrics and Gerontology, business, Dose selection

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bc63ec057985461f0f9c0f4e6f931c17
https://doi.org/10.1016/j.jalz.2017.07.245

المؤلفون: Stefan Viktor Vormfelde, Ulf Neumann, Kaj Blennow, Nicole Pezous, Sandrine Kretz, Marie-Laure Rouzade-Dominguez, Ana Graf, Erik Portelius, Valerie Dubost, Carine Kolly, Kina Höglund, Robert Vassar

المصدر: Alzheimer's & Dementia. 15:P872-P872

مصطلحات موضوعية: Pathology, medicine.medical_specialty, Morphology (linguistics), Epidemiology, business.industry, Health Policy, Hippocampal formation, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, medicine, Neurology (clinical), Geriatrics and Gerontology, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e2b204a639c7029dce90b745015289df
https://doi.org/10.1016/j.jalz.2019.06.4618

المؤلفون: Wolfgang Kaufmann, Susanne Müller, Lars Mecklenburg, Kelly Diegel, Carine Kolly, Jyoji Yamate, Silke Treumann, Dimitry M. Danilenko, Alys Bradley, Donna F. Kusewitt, E. Terence Adams

المصدر: Journal of Toxicologic Pathology

مصطلحات موضوعية: Pathology, medicine.medical_specialty, business.industry, Review, Toxicology, integumentary system, rodent pathology, Pathology and Forensic Medicine, The integument, diagnostic pathology, skin, rodent, histopathology, medicine, nomenclature, International harmonization, medicine.symptom, Mouse Integument, business, Nomenclature, Confusion

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d2ff419b2fdbabeff2c3d380f704a0d
https://doi.org/10.1293/tox.26.27s

المؤلفون: Vera Trappe, Diethilde Theil, Matthias Staufenbiel, Karen Beltz, Dittmar Tanja, Carine Kolly, Irena Brzak, Barbara Vogg, Wilfried Frieauff, Derya R. Shimshek, Valerie Dubost, Laura H. Jacobson, Ludovik Perrot, Magali Jivkov, Ulf Neumann

المصدر: Alzheimer's & Dementia. 12

مصطلحات موضوعية: 0301 basic medicine, Epidemiology, business.industry, Health Policy, Preclinical pharmacology, Pharmacology, 01 natural sciences, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, Psychiatry and Mental health, Cellular and Molecular Neuroscience, 030104 developmental biology, Developmental Neuroscience, Medicine, Neurology (clinical), Geriatrics and Gerontology, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1ecd984cd17189cbd350263175fa22bf
https://doi.org/10.1016/j.jalz.2016.06.831