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1
المؤلفون: Jiaqiang Cai, Bimjhana Bishwokarma, Dennis Leung, William J. Morris, Feroze Ujjainwalla, Candice Alleyne, Xiaoxing Du, Vincent J. Colandrea, Jennifer Piesvaux, Jianwu Bai, Liming Yang, Carla Alpert, Joseph M. Metzger, Vincenzo Pucci, Xiaofang Li, Jeffrey J. Hale, Dominique Stickens, Weiguo Quan, Byron G. DuBois, Rongqiang Liu, Mark Zielstorff, Chi-Sung Chiu, Christopher Joseph Sinz, Mangeng Cheng, Kallol Ray, Liping Wang, Ping Liu, Stella H. Vincent, Alejandro Crespo
المصدر: ACS Medicinal Chemistry Letters. 9:1193-1198
مصطلحات موضوعية: 0301 basic medicine, Chemistry, Anemia, Organic Chemistry, Increased hemoglobin, Pharmacology, medicine.disease, 030226 pharmacology & pharmacy, Biochemistry, In vitro, Bioavailability, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Orally active, Hypoxia-inducible factors, Oral administration, Drug Discovery, medicine
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2
المؤلفون: Kevin W. Johnson, Peter Fuller, Sujal V. Deshmukh, Fang He, Peter Goldenblatt, Lauren Dorosh, Hongbo Zeng, Jason D. Brubaker, Luis E. Torres, Tony Siu, Fiona Elwood, Charles A. Lesburg, Sangita B. Patel, Duan Liu, Elma Kadic, Christopher J. Dinsmore, Xavier Fradera, Lynsey Shaffer, Jonathan R. Young, Lily Y. Moy, Feng Shi, Carla Alpert, Joel A. Klappenbach, Joshua Close, Rafael Fernandez, Hongshi Yu, Nathan Bays, Dawn M. Mampreian
المصدر: Journal of Medicinal Chemistry. 60:9676-9690
مصطلحات موضوعية: 0301 basic medicine, Halogenation, Stereochemistry, medicine.drug_class, Carboxamide, Pyrazole, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Dogs, Drug Discovery, medicine, Animals, Humans, Structure–activity relationship, Protein Kinase Inhibitors, Ligand efficiency, Chemistry, Drug discovery, Janus Kinase 1, Ligand (biochemistry), Rats, Bioavailability, Molecular Docking Simulation, 030104 developmental biology, Pyran, Pyrazoles, Molecular Medicine
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3
المؤلفون: Peter J. Dandliker, Hao Tang, Christopher J. Dinsmore, Chi-Sung Chiu, Fiona Elwood, Deborah Slipetz, Jennifer Piesvaux, Sujal V. Deshmukh, Ilona Kariv, Bo-Sheng Pan, Carla Alpert, Nathan Bays, Alan Byford, Alexey Rivkin, Peter Goldenblatt, Irena Ivanovska, Mark E. Scott, Joel A. Klappenbach, Hyun-Hee Lee, David J. Witter, Kalyan Chakravarthy, Lauren Dorosh, Yujie Qu, Brian Kraybill, Mark Zielstorff
المصدر: The Journal of pharmacology and experimental therapeutics. 361(2)
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, Pharmacology, Biology, Isozyme, Autoimmune Diseases, 03 medical and health sciences, Piperidines, In vivo, Monitoring, Immunologic, medicine, Animals, Humans, Kinome, Pyrroles, Protein Kinase Inhibitors, Dose-Response Relationship, Drug, Kinase, Janus Kinase 3, Janus Kinase 1, Arthritis, Experimental, In vitro, Rats, Isoenzymes, Haematopoiesis, 030104 developmental biology, Cytokine, Pyrimidines, STAT protein, Molecular Medicine, Drug Monitoring
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30dcce0e8183db5060a7c6ebeec57fe3
https://pubmed.ncbi.nlm.nih.gov/28193636
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