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1
المؤلفون: David Lodge, Tracey K. Murray, Dell Colin Peter, Jaipal Singh, Todd R. Wiernicki, Deborah R. McCarty, Jerome H. Fleisch, David J. Osborne, Michael J. O'Neill, Kelly E. Patrick, Carlos R. Roman, Mark A Ward, Caroline A Hicks
المصدر: Brain Research. 871:234-244
مصطلحات موضوعية: Male, Time Factors, Amidines, Ischemia, Pharmacology, Endothelial NOS, Gerbil, Blood–brain barrier, Neuroprotection, Brain Ischemia, Cell Line, Nitric oxide, chemistry.chemical_compound, Enos, medicine, Animals, Humans, Drug Interactions, Enzyme Inhibitors, Molecular Biology, Dose-Response Relationship, Drug, Endothelin-1, biology, business.industry, General Neuroscience, biology.organism_classification, medicine.disease, Rats, Nitric oxide synthase, Disease Models, Animal, Neuroprotective Agents, medicine.anatomical_structure, chemistry, Reperfusion Injury, Anesthesia, biology.protein, Neurology (clinical), Nitric Oxide Synthase, Gerbillinae, business, Developmental Biology
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2
المؤلفون: J. Scott Sawyer, Sandra L. Cockerham, K. Jeff Thrasher, Larry L. Froelich, Carlos R. Roman, Bach Nicholas J, Peter W. Stengel, Jerome H. Fleisch, Steven A. Silbaugh
المصدر: Bioorganic & Medicinal Chemistry Letters. 6:249-252
مصطلحات موضوعية: LTD4 receptor, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Quinoline, Pharmaceutical Science, Pharmacology, Biochemistry, In vitro, Guinea pig, chemistry.chemical_compound, Membrane, Orally active, chemistry, In vivo, Drug Discovery, Molecular Medicine, Receptor, Molecular Biology
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32-alkyl-4-ethyl-5-[6-methyl-6-(2H-tetrazol-5-yl)heptyloxy]phenol leukotriene B4 receptor antagonists
المؤلفون: Michael J. Sofia, David K. Herron, Katrina Ann Nelson, Philip Marder, Theodore Goodson, Jerome H. Fleisch, Larry L. Froelich, Carlos R. Roman, Stephen M. Spaethe
المصدر: Bioorganic & Medicinal Chemistry Letters. 5:1995-2000
مصطلحات موضوعية: chemistry.chemical_classification, biology, Leukotriene B4, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Integrin, Leukotriene B4 receptor, Pharmaceutical Science, hemic and immune systems, respiratory system, Biochemistry, respiratory tract diseases, Guinea pig, chemistry.chemical_compound, chemistry, Drug Discovery, Parenchyma, biology.protein, Molecular Medicine, lipids (amino acids, peptides, and proteins), Phenols, Receptor, Molecular Biology, Alkyl
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4
المؤلفون: Carlos R. Roman, Floreancig Paul Edward, Sandra L. Cockerham, Baker, Larry L. Froelich, P. Marder, Jerome H. Fleisch, William T. Jackson, Bach Nicholas J, Michael J. Sofia
المصدر: Journal of Medicinal Chemistry. 36:3978-3981
مصطلحات موضوعية: Neutrophils, Leukotriene B4, Bronchoconstriction, Guinea Pigs, Receptors, Leukotriene B4, Tetrazoles, Structure-Activity Relationship, chemistry.chemical_compound, Phenols, Antigens, CD, In vivo, Oral administration, Drug Discovery, Animals, Humans, Lung, Molecular Structure, biology, CD11 Antigens, Cell Membrane, Leukotriene B4 receptor, Biological activity, In vitro, chemistry, Biochemistry, CD18 Antigens, biology.protein, Molecular Medicine, Muscle Contraction, Organic anion
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb123c949b12bc1b4783e6a0b1066970
https://doi.org/10.1021/jm00076a029 -
5
المؤلفون: Larry L. Froelich, Carlos R. Roman, Sandra L. Cockerham, Floreancig Paul Edward, William T. Jackson, Philip Marder, Michael J. Sofia, Peter W. Stengel, Steven A. Silbaugh, Jerome H. Fleisch, David L. Saussy
المصدر: Bioorganic & Medicinal Chemistry Letters. 3:1147-1152
مصطلحات موضوعية: Stereochemistry, Organic Chemistry, Clinical Biochemistry, Antagonist, Pharmaceutical Science, Biochemistry, In vitro, Sodium salt, Acetic acid, chemistry.chemical_compound, chemistry, In vivo, Drug Discovery, Molecular Medicine, Antagonism, Receptor, Molecular Biology
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6
المؤلفون: Jason Scott Sawyer, Floreancig Paul Edward, D. L. Jun. Saussy, Carlos R. Roman, Peter W. Stengel, Larry L. Froelich, Jerome H. Fleisch, Michael J. Sofia, Bach Nicholas J, Stephen Richard Baker, Sandra L. Cockerham, Stephen M. Spaethe, P. Marder, Elisabeth A. Schmittling, Baldwin Rf, J. A. Palkowitz, P. S. Borromeo, William T. Jackson, Steven A. Silbaugh
المصدر: ChemInform. 27
مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Stereochemistry, Leukotriene B4 receptor, Antagonist, General Medicine, Benzoic acid
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7
المؤلفون: David K. Herron, Steven A. Silbaugh, Theodore Goodson, Carlos R. Roman, Jerome H. Fleisch, Stephen M. Spaethe, Sandra L. Cockerham, David L. Saussy, Peter W. Stengel
المصدر: European Journal of Pharmacology. 223:57-64
مصطلحات موضوعية: Male, medicine.medical_specialty, Thromboxane, medicine.drug_class, Leukotriene B4, Guinea Pigs, Receptors, Leukotriene B4, Tetrazoles, In Vitro Techniques, Biology, Dinoprostone, Radioligand Assay, Thromboxane A2, chemistry.chemical_compound, Internal medicine, medicine, Animals, Receptors, Immunologic, Lung, Pharmacology, Analgesics, Leukotriene, Membranes, Pulmonary Gas Exchange, Leukotriene B4 receptor, Antagonist, respiratory system, Receptor antagonist, Prostaglandin Endoperoxides, Synthetic, respiratory tract diseases, Airway Obstruction, Endocrinology, chemistry, 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid, lipids (amino acids, peptides, and proteins), Lung Volume Measurements, Histamine, Muscle Contraction
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8
المؤلفون: David K. Herron, Bollinger Ng, Baldwin Rf, Jason Scott Sawyer, Carlos R. Roman, Richard Waltz Harper, L E Rinkema, Jerome H. Fleisch
المصدر: Journal of Medicinal Chemistry. 35:1191-1200
مصطلحات موضوعية: Male, Models, Molecular, Receptors, Leukotriene, LTD4 receptor, Leukotriene D4, Molecular Structure, Molecular model, Protein Conformation, Chemistry, Stereochemistry, Guinea Pigs, Antagonist, Tetrazoles, respiratory system, Chemical synthesis, Structure-Activity Relationship, chemistry.chemical_compound, Eicosanoid, Ileum, Drug Discovery, Animals, Molecular Medicine, Moiety, lipids (amino acids, peptides, and proteins), Receptors, Immunologic
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2faf4ca01a4db7df10dcbd6ff2b70b58
https://doi.org/10.1021/jm00085a004 -
9
المؤلفون: David P. Henry, Weihua L. Russell, Stephen M. Spaethe, Carlos R. Roman, Kerry G. Bemis, Jerome H. Fleisch, L E Rinkema, Winston Stanley Marshall
المصدر: Journal of Pharmacy and Pharmacology. 42:620-625
مصطلحات موضوعية: Male, medicine.medical_specialty, IBMX, medicine.drug_class, Muscle Relaxation, Guinea Pigs, Tetrazoles, Pharmaceutical Science, In Vitro Techniques, chemistry.chemical_compound, Theophylline, 1-Methyl-3-isobutylxanthine, Isoprenaline, Internal medicine, medicine, Animals, Receptors, Immunologic, Lung, Leukotriene E4, Receptors, Leukotriene, Pharmacology, Leukotriene, Chemistry, Leukotriene receptor, Isoproterenol, Acetophenones, Adrenergic beta-Agonists, Receptor antagonist, Bronchodilator Agents, Trachea, Endocrinology, Carbachol, SRS-A, Receptor antagonist activity, Muscle Contraction, medicine.drug
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10
المؤلفون: Daniel P. McLaughlin, John R. Boot, Graham N. Wishart, Caroline A Hicks, Mark A Ward, Kelly E. Patrick, Kusum S. Mathews, Michael J. O'Neill, Deborah R. McCarty, Jeremy Gilmore, Jerome H. Fleisch, Jonathan A. Stamford, David J. Osborne, Carlos R. Roman
المصدر: Brain research. 888(1)
مصطلحات موضوعية: Male, medicine.drug_class, Cell Survival, Ischemia, Calcium channel blocker, Pharmacology, In Vitro Techniques, Gerbil, Butylamines, Hippocampus, Brain Ischemia, Purkinje Cells, Sodium channel blocker, In vivo, medicine.artery, medicine, Animals, Channel blocker, Rats, Wistar, Furans, Molecular Biology, business.industry, General Neuroscience, Antagonist, Infarction, Middle Cerebral Artery, medicine.disease, Calcium Channel Blockers, Rats, Disease Models, Animal, Neuroprotective Agents, Anesthesia, Middle cerebral artery, Neurology (clinical), business, Gerbillinae, Developmental Biology, Sodium Channel Blockers