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المؤلفون: Nga N. Chung, Peter W. Schiller, Jason J. Guo, Grazyna Weltrowska, Brian C. Wilkes, Carole Lemieux
المصدر: Bioorganic & Medicinal Chemistry. 22:4581-4586
مصطلحات موضوعية: Intrinsic activity, Stereochemistry, medicine.drug_class, Clinical Biochemistry, Receptors, Opioid, mu, Pharmaceutical Science, Biochemistry, Partial agonist, Article, Carfentanil, Structure-Activity Relationship, Opioid receptor, Opioid Receptor Binding, mental disorders, Drug Discovery, medicine, Molecular Biology, Binding selectivity, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Organic Chemistry, Stereoisomerism, 3. Good health, Fentanyl, Molecular Docking Simulation, nervous system, Opioid, Docking (molecular), Molecular Medicine, medicine.drug
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المؤلفون: Joanna Mika, Joost Van Duppen, Katarzyna Popiolek-Barczyk, Attila Keresztes, John M. Streicher, Peter W. Schiller, Karel Guillemyn, Steven Ballet, Adriano Mollica, Jozef Vanden Broeck, Joanna Starnowska, Carole Lemieux, Barbara Przewlocka, Roberto Costante, Dirk Tourwé, Nga N. Chung
مصطلحات موضوعية: 0301 basic medicine, NK1 antagonists, Physiology, medicine.drug_class, Cognitive Neuroscience, Analgesic, Receptors, Opioid, mu, Hybrid peptides, Substance P, Pharmacology, opioid agonism, Ligands, Biochemistry, Article, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Receptors, Opioid, delta, medicine, Animals, Receptor, Spinal Cord Injuries, neuropathic pain, Analgesics, Chemistry, acute pain, Cell Biology, General Medicine, Receptors, Neurokinin-1, Receptor antagonist, Constriction, Analgesics, Opioid, 030104 developmental biology, Opioid, Spinal Cord, Neuropathic pain, Chronic Disease, Neuralgia, NK1 receptor antagonist, μ-opioid receptor, 030217 neurology & neurosurgery, medicine.drug
وصف الملف: Print-Electronic
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbdd56be47ca77328f58848e3431857d
https://lirias.kuleuven.be/handle/123456789/632022 -
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المؤلفون: Sofie Stalmans, Steven Ballet, Carole Lemieux, Dirk Tourwé, Nathalie Bracke, Mariana Spetea, Mark E. Cooper, Peter W. Schiller, Bart De Spiegeleer, Evelien Wynendaele, Sylvia Van Dorpe, Johannes Zuegg, Cecilia Betti, Alexandre Novoa, Nga N. Chung
المصدر: Journal of Medicinal Chemistry. 55:9549-9561
مصطلحات موضوعية: Nociception, Agonist, Biodistribution, Stereochemistry, medicine.drug_class, Peptide, Article, Mice, Structure-Activity Relationship, Drug Discovery, Side chain, medicine, Animals, Structure–activity relationship, Peptide bond, Tissue Distribution, Pain Measurement, chemistry.chemical_classification, Molecular Structure, Chemistry, digestive, oral, and skin physiology, Brain, Analgesics, Opioid, Opioid Peptides, Blood-Brain Barrier, Receptors, Opioid, Lipophilicity, Molecular Medicine, μ-opioid receptor, Oligopeptides
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4
المؤلفون: Nga N. Chung, Carole Lemieux, Jinguo Ding, Peter W. Schiller
المصدر: Chemical Biology & Drug Design. 79:186-193
مصطلحات موضوعية: Pharmacology, Agonist, medicine.drug_class, Stereochemistry, Chemistry, Organic Chemistry, Antagonist, Biochemistry, Opioid, Naltrindole, Opioid receptor, Opioid Receptor Binding, Drug Discovery, medicine, Molecular Medicine, Opioid peptide, Opioid antagonist, medicine.drug
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المؤلفون: Carole Lemieux, Nga N. Chung, Peter W. Schiller, Yixin Lu, Grazyna Weltrowska, Jianxin Guo, Brian C. Wilkes
المصدر: Journal of Medicinal Chemistry. 53:2875-2881
مصطلحات موضوعية: Agonist, Stereochemistry, medicine.drug_class, Transmembrane domain, chemistry.chemical_compound, chemistry, Opioid, Docking (molecular), Opioid receptor, Opioid Receptor Binding, Drug Discovery, medicine, Molecular Medicine, Piperidine, Receptor, medicine.drug
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المصدر: Journal of Medicinal Chemistry. 52:6941-6945
مصطلحات موضوعية: Models, Molecular, Agonist, Binding Sites, Dipeptide, Tetrapeptide, Protein Conformation, medicine.drug_class, Stereochemistry, Antagonist, Phenylalanine, Molecular Dynamics Simulation, Ligands, Article, chemistry.chemical_compound, chemistry, Receptors, Opioid, delta, Drug Discovery, Peptide synthesis, medicine, Tyrosine, Molecular Medicine, Opioid peptide, Oligopeptides, Opioid antagonist
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المؤلفون: Peter W. Schiller, Kenneth L. Kirk, Louis A. Cohen, Virender M. Labroo, D. Hebel, Carole Lemieux
المصدر: International Journal of Peptide and Protein Research. 37:430-439
مصطلحات موضوعية: Stereochemistry, Molecular Sequence Data, Receptors, Opioid, mu, Peptide, Biochemistry, Sulfone, Merrifield resin, chemistry.chemical_compound, Receptors, Opioid, delta, Peptide synthesis, Animals, Amino Acid Sequence, Opioid peptide, chemistry.chemical_classification, Tetrapeptide, Electrophilic fluorination, Brain, Fluorine, Dermorphin, Rats, Analgesics, Opioid, Opioid Peptides, chemistry, Receptors, Opioid, Tyrosine, Oligopeptides
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7d1a1914897aef8513c50fe69fe613a
https://doi.org/10.1111/j.1399-3011.1991.tb00758.x -
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المؤلفون: Nga N. Chung, Ralf Schmidt, Peter W. Schiller, András Kálmán, Csaba Horváth, Carole Lemieux
المصدر: International Journal of Peptide and Protein Research. 46:47-55
مصطلحات موضوعية: Male, Stereochemistry, Narcotic Antagonists, Deltorphin I, Guinea Pigs, Molecular Sequence Data, Receptors, Opioid, mu, Methylation, Biochemistry, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Residue (chemistry), Vas Deferens, Ileum, Receptors, Opioid, delta, Animals, Peptide bond, Amino Acid Sequence, Opioid peptide, Peptide sequence, Chromatography, High Pressure Liquid, Pipecolic acid, chemistry.chemical_classification, Cell Membrane, Temperature, Brain, Dermorphin, Rats, Amino acid, Opioid Peptides, chemistry, Oligopeptides
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faf1a3d5d1e5b0dff3714be55de5a37e
https://doi.org/10.1111/j.1399-3011.1995.tb00580.x -
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المؤلفون: Nga N. Chung, Ralf Schmidt, Peter W. Schiller, Brian C. Wilkes, Carole Lemieux
المصدر: International Journal of Peptide and Protein Research. 48:411-419
مصطلحات موضوعية: Agonist, chemistry.chemical_classification, Stereochemistry, medicine.drug_class, Deltorphin I, Antagonist, Peptide, Biochemistry, δ-opioid receptor, chemistry.chemical_compound, chemistry, medicine, μ-opioid receptor, Opioid peptide, Opioid antagonist
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::978f936bfc0d2728acb2b6562223ad4b
https://doi.org/10.1111/j.1399-3011.1996.tb00859.x -
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المؤلفون: Peter W. Schiller, Carole Lemieux, Grazyna Weltrowska, N.N. Chung
المصدر: The Journal of Peptide Research. 65:36-41
مصطلحات موضوعية: chemistry.chemical_classification, Agonist, Enkephalin, medicine.drug_class, Stereochemistry, Peptide, Morphinans, Biochemistry, In vitro, Endocrinology, chemistry, Opioid, medicine, Receptor, Opioid peptide, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b8a30386e1558a469d3de44cc4d00a8e
https://doi.org/10.1111/j.1399-3011.2004.00190.x