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المؤلفون: Joshua E. Allen, Stéphane A. Laporte, J. Robert Lane, David R. Sibley, Yoon Namkung, R. Benjamin Free, Blair K. A. Willette, Bing Xie, Marta Sánchez-Soto, Caroline A. Cuoco, Varun V. Prabhu, Lei Shi, Marilyn M. Day
المصدر: Mol Pharmacol
مصطلحات موضوعية: Pyridines, Allosteric regulation, Antineoplastic Agents, CHO Cells, Pharmacology, Protein Structure, Secondary, Cricetulus, Allosteric Regulation, Dopamine, Cricetinae, Dopamine receptor D2, medicine, Animals, Humans, Binding site, Receptor, Dose-Response Relationship, Drug, Receptors, Dopamine D2, Chemistry, Imidazoles, Articles, Dopamine D2 Receptor Antagonists, HEK293 Cells, Pyrimidines, Mechanism of action, Dopamine receptor, Molecular Medicine, medicine.symptom, Antagonism, Protein Binding, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9c3bea86988ed516a101a85ffbfb526
https://doi.org/10.1124/molpharm.121.000336 -
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المؤلفون: Leonard Yoon, Rachel C. Botham, Adriaan Verhelle, Pablo Sanz-Martinez, Jin Xu, Christian M. Cole, Ee Phie Tan, Ching Chieh Chou, Caroline A. Cuoco, Lynée A. Massey, Sergio Labra, Lisa P. Elia, Amina Ta, Maziar S. Ardejani, Kyunga Lee, Gabriel M. Kline, Qiang Xiao, Sara Cano-Franco, Nora J. Lyang, William C. Hou, Anan Yu, Susan Fox, Yeonjin Ko, Cristian Wulkop-Gil, Lara H. Ibrahim, Starr Jiang, Alina Meneses, Luke T. Nelson, Hongfan Peng, Stuart A. Lipton, Michael J. Bollong, Malene Hansen, Richard I. Morimoto, H. Michael Petrassi, R. Luke Wiseman, Evan T. Powers, Steven Finkbeiner, Danny Garza, Daniel Finley, Miguel A. Prado, Ivan Dikic, Judith Frydman, Kristen A. Johnson, M. Catarina Silva, Stephen J. Haggarty, Alexandra Stolz, Sandra E. Encalada, Jeffery W. Kelly
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8e6dc4b0e683bc6167610911ea432da2
https://doi.org/10.1101/2022.09.29.509997 -
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المؤلفون: Charles David Weaver, Emily Days, Craig W. Lindsley, Alice L. Rodriguez, Paige N. Vinson, Colleen M. Niswender, Anna L. Blobaum, Matthew T. Loch, Caroline Anne Cuoco, P.J. Conn, Krystian A. Kozek, Mark G. Fulton
المصدر: Letters in Drug Design & Discovery
مصطلحات موضوعية: medicine.drug_class, Stereochemistry, Allosteric regulation, Pharmaceutical Science, Carboxamide, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Amide, Drug Discovery, medicine, Structure–activity relationship, metabotropic glutamate receptor, Receptor, Xanthine oxidase inhibitor, Heterodimer, striatopallidal synapses, 030304 developmental biology, Letters in Drug Design & Discovery, 0303 health sciences, mGlu2/4, Chemistry, structure-activity relationship, Metabotropic glutamate receptor, positive allosteric modulator, Molecular Medicine, Febuxostat, 030217 neurology & neurosurgery, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12744d2df7d05c9a81a50373a85b8687
https://doi.org/10.2174/1570180815666181017131349 -
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المؤلفون: Sean Deacon, Martin Stogniew, Joshua E. Allen, Caroline A. Cuoco, R. Benjamin Free, Joseph Rucker, Varun V. Prabhu, David R. Sibley, Chidananda Sulli, Lakshmi Anantharaman, Wolfgang Oster, Benjamin J. Doranz, Marilyn M. Day, Edgar Davidson, J. Robert Lane, Neil Charter, Blair K. A. Willette
المصدر: Neuro Oncol
مصطلحات موضوعية: Drd2 gene, Cancer Research, Neurologic Oncology, Receptor pharmacology, business.industry, Neuro oncology, Antagonist, Pharmacology, Oncology, Dopamine receptor, Dopamine receptor D2, Tumor regression, Medicine, Experimental Therapeutics, Neurology (clinical), business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0c41d688770375ff704a83407a6fd1d
https://europepmc.org/articles/PMC6847112/ -
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المؤلفون: Caroline A. Cuoco, Mark R. Gilbert, Varun V. Prabhu, Neil Charter, Lakshmi Anantharaman, Blair K. A. Willette, Jinkyu Jung, Abed Rahman Kawakibi, R. Benjamin Free, Benjamin J. Doranz, Martin Stogniew, Joshua E. Allen, Wolfgang Oster, Joseph Rucker, David R. Sibley, Marilyn M. Day
المصدر: Neuro Oncol
مصطلحات موضوعية: Drd2 gene, Cancer Research, Receptor pharmacology, business.industry, Allosteric regulation, Antagonist, Pharmacology, Oncology, Dopamine receptor D2, Drug Discovery, Structure–activity relationship, Medicine, Neurology (clinical), business, Personal Integrity, G protein-coupled receptor
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8452f35618af80dff5922e2f235ec552
https://europepmc.org/articles/PMC6846870/ -
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المؤلفون: R. Benjamin Free, David R. Sibley, Blair K. A. Willette, J. Robert Lane, Joshua E. Allen, Caroline A. Cuoco
المصدر: The FASEB Journal. 33
مصطلحات موضوعية: Drug, Chemistry, media_common.quotation_subject, Pharmacology, medicine.disease, Biochemistry, Dopamine receptor, Genetics, medicine, Binding site, Non competitive, Molecular Biology, Biotechnology, media_common, Glioblastoma
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المؤلفون: Joseph Rucker, Sara Morrow, Jinkyu Jung, Joel Basken, Lakshmi Anantharaman, David R. Sibley, Neil Charter, Blair K. A. Willette, Abed Rahman Kawakibi, Martin Stogniew, Joshua E. Allen, Caroline A. Cuoco, Varun V. Prabhu, Marilyn M. Day, Benjamin J. Doranz, Mark R. Gilbert, R. Free
المصدر: Neuro Oncol
مصطلحات موضوعية: Drd2 gene, Cancer Research, Chemistry, medicine.disease, Small molecule, Cell biology, Gene expression profiling, Oncology, Gene expression, medicine, Tumor regression, Drug Discovery, Drug Resistance, Neurology (clinical), Glioblastoma
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cec78251a0e0959003e4256a4981be9
https://doi.org/10.1093/neuonc/noaa215.278 -
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المؤلفون: Neil Charter, Caroline A. Cuoco, Joseph Rucker, David R. Sibley, Varun V. Prabhu, Ultan McDermott, Lakshmi Anantharaman, Neel Madhukar, Sharon DeMorrow, Matthew J. Garnett, Joel Basken, Mark R. Gilbert, Olivier Elemento, Jinkyu Jung, Wolfgang Oster, Abed Rahman Kawakibi, Cyril H. Benes, Benjamin J. Doranz, R. Benjamin Free, Sara Morrow, Robert J. Wechsler-Reya, Martin Stogniew
المصدر: Cancer Research. 80:5688-5688
مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, No-observed-adverse-effect level, Chemistry, Allosteric regulation, Antagonist, Cmax, medicine.disease, Cell culture, Internal medicine, Glioma, medicine, Potency, Antagonism
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f65ab5fbddc0b7dc1f865ac04a92267f
https://doi.org/10.1158/1538-7445.am2020-5688 -
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المؤلفون: Blair K. A. Willette, David R. Sibley, J. Robert Lane, Joshua E. Allen, Caroline A. Cuoco, Marilyn M. Day, R. Benjamin Free
المصدر: The FASEB Journal. 32
مصطلحات موضوعية: business.industry, Cancer, biochemical phenomena, metabolism, and nutrition, medicine.disease, Biochemistry, Small molecule, Clinical trial, Dopamine receptor, Genetics, Cancer research, Medicine, Non competitive, business, Molecular Biology, Biotechnology