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المؤلفون: Sushovan Guha, Christopher R. Ireson, Enrique Rozengurt, Bharat B. Aggarwal, Sunil Krishnan, Juri Gelovani, James Sinnett-Smith, Yoichi Matsuo, Parmeswaran Diagaradjane, Dipen Maru, Muddasar Farooq, Alexandra Boakes, Caroline Foxton, Azadeh Bagherzadeh, Mark Charles, Tony Raynham, Rachel Sutherland, Stephen Jamieson, Lloyd Kelland, Bokyung Sung, Amit Deorukhkar, Zhimin Tong, Nobuo Ochi, Ajaikumar B. Kunnumakkara, Kuzhuvelil B. Harikumar
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab32f00e1cc289882edd000632bf0373
https://doi.org/10.1158/1535-7163.c.6531675.v1 -
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المؤلفون: Sushovan Guha, Christopher R. Ireson, Enrique Rozengurt, Bharat B. Aggarwal, Sunil Krishnan, Juri Gelovani, James Sinnett-Smith, Yoichi Matsuo, Parmeswaran Diagaradjane, Dipen Maru, Muddasar Farooq, Alexandra Boakes, Caroline Foxton, Azadeh Bagherzadeh, Mark Charles, Tony Raynham, Rachel Sutherland, Stephen Jamieson, Lloyd Kelland, Bokyung Sung, Amit Deorukhkar, Zhimin Tong, Nobuo Ochi, Ajaikumar B. Kunnumakkara, Kuzhuvelil B. Harikumar
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::146fb75ff91e4ab866310a4198e944e7
https://doi.org/10.1158/1535-7163.22484955 -
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المؤلفون: Lesley Gilmour, Jonathan Clark, Simon J. Cook, Lan-Zhen Wang, Pamela A. Lochhead, Matthew Squires, Rebecca Gilley, Stephen R. Wedge, Caroline Foxton, David R. Newell
المصدر: Cell Cycle
مصطلحات موضوعية: Proto-Oncogene Proteins B-raf, 0301 basic medicine, Indoles, Colorectal cancer, Cell, MAPK7, tumor cell proliferation, Biology, medicine.disease_cause, Proto-Oncogene Proteins p21(ras), Cell Cycle News & Views, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, medicine, Humans, RNA, Small Interfering, Protein Kinase Inhibitors, MEK5, Molecular Biology, Mitogen-Activated Protein Kinase 7, Cell Proliferation, selumetinib, Aniline Compounds, BIX02189, Cell growth, Extra View, Cancer, RAF, Cell Biology, medicine.disease, ERK5, 030104 developmental biology, medicine.anatomical_structure, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Mutation, Cancer cell, Immunology, Cancer research, Selumetinib, Benzimidazoles, KRAS, Colorectal Neoplasms, Signal Transduction, RAS, Developmental Biology
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المؤلفون: Mar Jimenez Quesada, Ellen Catherine Macdonald, Allan M. Jordan, Caroline Foxton, Huib Ovaa, Pritom Shah, Elisabeth Trivier, Aurore Lejeune, Tony Raynham, Wouter H. Moolenaar, Muddasar Farooq, Martin Stockley, P.J. Owen, James R. Hitchin, Jana Skeete, Michelle Pritchard, Irene Farre Gutierrez, Hamish Ryder, Niall M. Hamilton, Andrew P. Turnbull, Anne Cheasty, Leon Pang, Alexandra Stowell, Susan M. Boyd
المصدر: Bioorganic and Medicinal Chemistry Letters, 26(22), 5403-5410
مصطلحات موضوعية: 0301 basic medicine, Pyridines, Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, Inflammation, Crystallography, X-Ray, Biochemistry, Mice, 03 medical and health sciences, 0302 clinical medicine, In vivo, Neoplasms, Drug Discovery, Hydrolase, medicine, Animals, Humans, Molecular Targeted Therapy, Enzyme Inhibitors, Molecular Biology, Cancer, biology, Phosphoric Diester Hydrolases, Chemistry, Zinc ion, Organic Chemistry, Active site, Lysophosphatidic acid (LPA), Autotaxin (ATX), Small molecule, Molecular Docking Simulation, 030104 developmental biology, Lysophospholipase, Lysophosphatidylcholine (LPC), 030220 oncology & carcinogenesis, biology.protein, Molecular Medicine, lipids (amino acids, peptides, and proteins), Lysophospholipids, medicine.symptom, Autotaxin
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a7b70a8962d8c311e0ac46deffdc0f8
https://hdl.handle.net/1887/111844 -
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المؤلفون: Ajaikumar B. Kunnumakkara, Mark Charles, Sunil Krishnan, Juri G. Gelovani, Zhimin Tong, Yoichi Matsuo, Azadeh Bagherzadeh, Parmeswaran Diagaradjane, James Sinnett-Smith, Lloyd R. Kelland, Rachel Sutherland, Caroline Foxton, Christopher R. Ireson, Tony Raynham, Sushovan Guha, Stephen Jamieson, Bharat B. Aggarwal, Muddasar Farooq, Alexandra Boakes, Nobuo Ochi, Kuzhuvelil B. Harikumar, Bokyung Sung, Enrique Rozengurt, Amit Deorukhkar, Dipen M. Maru
مصطلحات موضوعية: Male, Cancer Research, medicine.medical_specialty, Proliferation index, endocrine system diseases, Administration, Oral, Mice, Nude, Antineoplastic Agents, Apoptosis, Biology, Article, Mice, Internal medicine, Pancreatic cancer, Cell Line, Tumor, Survivin, medicine, Animals, Humans, Protein Kinase Inhibitors, Protein kinase C, Protein Kinase C, Cell Proliferation, Kinase, Cancer, medicine.disease, Xenograft Model Antitumor Assays, Molecular Weight, Pancreatic Neoplasms, Endocrinology, Pyrimidines, Oncology, Cancer cell, Cancer research, Protein kinase D1, Carcinoma, Pancreatic Ductal
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e0b3fb4ce0d44e4895652a9ed0caafe
https://europepmc.org/articles/PMC2905628/ -
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المؤلفون: Wasiru Olugbenga Saka, Denis Talbot, Simon Pacey, Glenda Laviste, Robert McLeod, Caroline Foxton, Mirela Hategan, Alberto Fusi, Fiona H Blackhall, Susan Wan, Javier Garcia-Corbacho, Ioannis Karydis, Sarah Halford
المصدر: ResearcherID
مصطلحات موضوعية: Cancer Research, biology, business.industry, VEGF receptors, MEK inhibitor, Pharmacology, Vandetanib, respiratory tract diseases, Oncology, Tolerability, Cancer research, medicine, biology.protein, Selumetinib, Dose escalation, Non small cell, business, medicine.drug, EGFR inhibitors
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f44b64d736e97807c22d1647b44f5a7
https://doi.org/10.1200/jco.2015.33.15_suppl.2583 -
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المؤلفون: Caroline Foxton, Juliet Williams, Tony Raynham, Elizabeth Trivier, Michelle Riddick, Rebecca W. Scott, Steven Hooper, Diane Crighton, Mark Charles, Michael F. Olson, Martin Stockley, Joanna Brookfield, Erik Sahai, Tennyson Ekwuru, Tim Hammonds
المصدر: Molecular Cancer Therapeutics. 8:C210-C210
مصطلحات موضوعية: Cancer Research, biology, Matrigel Invasion Assay, Kinase, Cancer, Rho family of GTPases, Cofilin, Actin cytoskeleton, medicine.disease, Cell biology, Lim kinase, Oncology, biology.protein, medicine, Signal transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e861ec7b1b4e35ab69ef91b52e501fb4
https://doi.org/10.1158/1535-7163.targ-09-c210
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