المؤلفون: Ya-Fei Xu, Mercedes Prudencio, Jaime M Hubbard, Jimei Tong, Ena C Whitelaw, Karen Jansen-West, Caroline Stetler, Xiangkun Cao, John Song, Yong-Jie Zhang

المصدر: PLoS ONE, Vol 8, Iss 7, p e69864 (2013)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3724736?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/9614c87237f4476facd0a0dec7799db4

المؤلفون: Mercedes Prudencio, Aishe Kurti, Jeannette N. Stankowski, Dennis W. Dickson, Linda Rousseau, Emilie A. Perkerson, Yong Jie Zhang, Tania F. Gendron, Ena C. Whitelaw, Dieter Edbauer, Peter O. Bauer, Karen Overstreet, Lillian M. Daughrity, Leonard Petrucelli, Pamela Desaro, Karen Jansen-West, Kevin F. Bieniek, John D. Fryer, Melissa E. Murray, Amelia Johnston, Rosa Rademakers, Monica Castanedes-Casey, Chris W. Lee, Hiroki Sasaguri, Caroline Stetler, Jeannie Chew, Kevin B. Boylan

المصدر: Science

مصطلحات موضوعية: Pathology, medicine.medical_specialty, Multidisciplinary, Neurodegeneration, Cerebellar Purkinje cell, Biology, medicine.disease, Astrogliosis, C9orf72 Protein, C9orf72, medicine, Amyotrophic lateral sclerosis, Trinucleotide repeat expansion, Engineering sciences. Technology, Frontotemporal dementia

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9340e0776496c05cc423327f356727d5
https://doi.org/10.1126/science.aaa9344

المؤلفون: Michael DeTure, Mary D. Davis, Caroline Stetler, Leonard Petrucelli, Casey Cook, Dennis W. Dickson, Kristyn Scheffel, Matthew Jarpe, Judy Dunmore, Tania F. Gendron, Yari Carlomagno

المصدر: Human Molecular Genetics

مصطلحات موضوعية: Male, Tau protein, Amino Acid Motifs, tau Proteins, Biology, Histone Deacetylase 6, Hydroxamic Acids, Histone Deacetylases, 03 medical and health sciences, Mice, 0302 clinical medicine, Alzheimer Disease, Genetics, medicine, Animals, Humans, Phosphorylation, Molecular Biology, Genetics (clinical), 030304 developmental biology, Aged, Aged, 80 and over, 0303 health sciences, HEK 293 cells, Acetylation, General Medicine, Articles, HDAC6, medicine.disease, 3. Good health, Cell biology, Histone Deacetylase Inhibitors, Chronic traumatic encephalopathy, Disease Models, Animal, HEK293 Cells, Pyrimidines, Biochemistry, biology.protein, Female, Tauopathy, Alzheimer's disease, Protein Multimerization, 030217 neurology & neurosurgery, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1c19214d0366262286b0fc1b3361e35
http://europepmc.org/articles/PMC3857946

المؤلفون: Jennifer Gass, Leonard Petrucelli, Caroline Stetler, Mercedes Prudencio

المصدر: Brain Research. 1462:118-128

مصطلحات موضوعية: Inflammation, Disease, Biology, medicine.disease_cause, Article, Mice, Progranulins, Neurotrophic factors, mental disorders, medicine, Animals, Humans, Dementia, Nerve Growth Factors, Molecular Biology, Wound Healing, Mutation, General Neuroscience, Neurodegeneration, Cancer, Frontotemporal lobar degeneration, medicine.disease, Disease Models, Animal, Intercellular Signaling Peptides and Proteins, Neurology (clinical), Frontotemporal Lobar Degeneration, medicine.symptom, Neuroscience, Signal Transduction, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b65a97f52d4a4f83d005bedd2b311d45
https://doi.org/10.1016/j.brainres.2012.01.047

المؤلفون: Christian A. Ross, Mary D. Davis, Sherri M. Biendarra, Marka van Blitterswijk, Mercedes Prudencio, Ralph B. Perkerson, Amelia E Piazza-Johnston, Caroline Stetler, Ranjan Batra, Kevin F. Bieniek, Karen Overstreet, Rosa Rademakers, Kevin B. Boylan, Leonard Petrucelli, Hu Li, Matt Baker, Christopher D. Link, Luc Pregent, Michael DeTure, Melissa E. Murray, Tania F. Gendron, Pamela Desaro, Veronique V. Belzil, Wing C. Lee, Dennis W. Dickson

المصدر: Nature neuroscience

مصطلحات موضوعية: Adult, Polyadenylation, Biology, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, C9orf72, Cerebellum, parasitic diseases, medicine, Humans, Amyotrophic lateral sclerosis, Genetic Association Studies, 030304 developmental biology, Aged, Regulation of gene expression, Genetics, 0303 health sciences, C9orf72 Protein, Heterogeneous-Nuclear Ribonucleoprotein Group F-H, Sequence Analysis, RNA, General Neuroscience, Alternative splicing, Amyotrophic Lateral Sclerosis, C9orf72 Gene, RNA, Proteins, Middle Aged, medicine.disease, Frontal Lobe, Alternative Splicing, Gene Expression Regulation, Human medicine, Neuroscience, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c4c886437ded21eaa7525c31003118d
https://pubmed.ncbi.nlm.nih.gov/26240037

المؤلفون: Jeannie, Chew, Tania F, Gendron, Mercedes, Prudencio, Hiroki, Sasaguri, Yong-Jie, Zhang, Monica, Castanedes-Casey, Chris W, Lee, Karen, Jansen-West, Aishe, Kurti, Melissa E, Murray, Kevin F, Bieniek, Peter O, Bauer, Ena C, Whitelaw, Linda, Rousseau, Jeannette N, Stankowski, Caroline, Stetler, Lillian M, Daughrity, Emilie A, Perkerson, Pamela, Desaro, Amelia, Johnston, Karen, Overstreet, Dieter, Edbauer, Rosa, Rademakers, Kevin B, Boylan, Dennis W, Dickson, John D, Fryer, Leonard, Petrucelli

المصدر: Science / Science now 348(6239), 1151-1154 (2015). doi:10.1126/science.aaa9344

مصطلحات موضوعية: N-glycylalanine, genetics [DNA-Binding Proteins], metabolism [Purkinje Cells], Purkinje Cells, Mice, genetics [Antisocial Personality Disorder], Animals, Humans, pathology [Amyotrophic Lateral Sclerosis], genetics [Frontotemporal Dementia], RNA, Nuclear, Cerebral Cortex, C9orf72 Protein, metabolism [Cerebral Cortex], Amyotrophic Lateral Sclerosis, pathology [Antisocial Personality Disorder], metabolism [Dipeptides], Gene Transfer Techniques, Proteins, Antisocial Personality Disorder, Dipeptides, Dependovirus, genetics [Proteins], pathology [Purkinje Cells], DNA-Binding Proteins, genetics [Amyotrophic Lateral Sclerosis], Disease Models, Animal, HEK293 Cells, metabolism [RNA, Nuclear], Frontotemporal Dementia, ddc:320, pathology [Frontotemporal Dementia], pathology [Cerebral Cortex], glycylproline, C9orf72 protein, human

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6b5a07fe5be13274ebfc8ab2239f3e33

المؤلفون: Peter O. Bauer, Yong Jie Zhang, Hiroki Sasaguri, Jeannie Chew, Karen Jansen-West, Mercedes Prudencio, Sandra Almeida, Tania F. Gendron, Thomas R. Caulfield, Leonard Petrucelli, William M. Tay, Ian R. A. Mackenzie, Fen-Biao Gao, Wing C. Lee, Caroline Stetler, Ni Cole A. Finch, Rosa Rademakers

المصدر: Human molecular genetics
Human Molecular Genetics

مصطلحات موضوعية: Pyridines, Induced Pluripotent Stem Cells, Haploinsufficiency, Biology, Endocytosis, Progranulins, Cell Line, Tumor, mental disorders, Genetics, Extracellular, medicine, Humans, Lymphocytes, Induced pluripotent stem cell, Molecular Biology, Genetics (clinical), HEK 293 cells, Signal transducing adaptor protein, Genetic Variation, Reproducibility of Results, General Medicine, Frontotemporal lobar degeneration, Articles, medicine.disease, 3. Good health, Cell biology, Adaptor Proteins, Vesicular Transport, Chemistry, HEK293 Cells, Frontotemporal Dementia, Immunology, Intercellular Signaling Peptides and Proteins, Human medicine, Frontotemporal dementia

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa35d7d2f1edf35d8622e7ad2d75882

المؤلفون: Xiangkun Cao, Ena C. Whitelaw, Jimei Tong, Caroline Stetler, Yong Jie Zhang, Ya Fei Xu, Mercedes Prudencio, Karen Jansen-West, Jaime Hubbard, John Song

المصدر: PLoS ONE
PLoS ONE, Vol 8, Iss 7, p e69864 (2013)

مصطلحات موضوعية: Pathology, Mouse, lcsh:Medicine, Biochemistry, Gene Splicing, Motor Neuron Diseases, Mice, 0302 clinical medicine, Neurobiology of Disease and Regeneration, lcsh:Science, Sortilin 1, Animal Management, 0303 health sciences, Multidisciplinary, Homozygote, Agriculture, Neurochemistry, Neurodegenerative Diseases, Frontotemporal lobar degeneration, Animal Models, Cell biology, DNA-Binding Proteins, Nucleic acids, Phenotype, Neurology, RNA splicing, Medicine, Genetic Engineering, Transgenic Animals, Research Article, Biotechnology, Genetically modified mouse, medicine.medical_specialty, Transgene, Dendritic Spines, Down-Regulation, Mice, Transgenic, Biology, Protein Chemistry, 03 medical and health sciences, Model Organisms, Downregulation and upregulation, mental disorders, medicine, Genetics, Animals, Humans, RNA, Messenger, Loss function, 030304 developmental biology, Injections, Intraventricular, Hemizygote, lcsh:R, Alternative splicing, Amyotrophic Lateral Sclerosis, nutritional and metabolic diseases, Proteins, medicine.disease, nervous system diseases, Alternative Splicing, Disease Models, Animal, Animals, Newborn, RNA processing, Synapses, RNA, lcsh:Q, Frontotemporal Lobar Degeneration, Molecular Neuroscience, 030217 neurology & neurosurgery, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dc174769fc6d356fdeb7aa689e3c58b
https://pubmed.ncbi.nlm.nih.gov/23922830

المؤلفون: Tania F. Gendron, Hiroki Sasaguri, Wing C. Lee, Shuyi Cai, Thomas R. Caulfield, Caroline Stetler, Ena C. Whitelaw, Ya Fei Xu, Yong Jie Zhang, Jaime Hubbard, Leonard Petrucelli

المصدر: Human Molecular Genetics

مصطلحات موضوعية: Models, Anatomic, Protein Folding, Protein Conformation, RNA Splicing, Inclusion bodies, 03 medical and health sciences, 0302 clinical medicine, Protein structure, Ubiquitin, mental disorders, Genetics, medicine, Humans, Protein Interaction Domains and Motifs, Molecular Biology, Genetics (clinical), 030304 developmental biology, Inclusion Bodies, 0303 health sciences, biology, Protein Stability, Amyotrophic Lateral Sclerosis, nutritional and metabolic diseases, General Medicine, Articles, medicine.disease, Cell biology, nervous system diseases, Folding (chemistry), DNA-Binding Proteins, Frontotemporal Dementia, RNA splicing, biology.protein, Protein folding, Protein Multimerization, 030217 neurology & neurosurgery, Function (biology), Frontotemporal dementia

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ede2bee0e05175983933e5848f90d6cf
https://pubmed.ncbi.nlm.nih.gov/23575225

المؤلفون: Dennis W. Dickson, Luc Pregent, Tania F. Gendron, Leonard Petrucelli, Mercedes Prudencio, Lillian M. Daughrity, Kevin B. Boylan, Rosa Rademakers, Peter O. Bauer, Caroline Stetler, Tushar Patel, Matt Baker, Veronique V. Belzil, Irene K. Yan

المصدر: Acta neuropathologica
Acta Neuropathologica

مصطلحات موضوعية: Clinical Neurology, Biology, Histone methylation, Pathology and Forensic Medicine, 03 medical and health sciences, Histone H3, Cellular and Molecular Neuroscience, 0302 clinical medicine, C9orf72, Epigenetics, 030304 developmental biology, 0303 health sciences, Original Paper, Epigenetic modification, Repeat expansion, Amyotrophic lateral sclerosis, Molecular biology, 3. Good health, C9orf72 Protein, Histone, DNA methylation, biology.protein, Neurology (clinical), Human medicine, Trinucleotide repeat expansion, Chromatin immunoprecipitation, 030217 neurology & neurosurgery, Frontotemporal dementia

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8bc0cbe584f7629b467c26dfc20ed4d