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1دورية أكاديمية
المؤلفون: Ya-Fei Xu, Mercedes Prudencio, Jaime M Hubbard, Jimei Tong, Ena C Whitelaw, Karen Jansen-West, Caroline Stetler, Xiangkun Cao, John Song, Yong-Jie Zhang
المصدر: PLoS ONE, Vol 8, Iss 7, p e69864 (2013)
وصف الملف: electronic resource
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المؤلفون: Mercedes Prudencio, Aishe Kurti, Jeannette N. Stankowski, Dennis W. Dickson, Linda Rousseau, Emilie A. Perkerson, Yong Jie Zhang, Tania F. Gendron, Ena C. Whitelaw, Dieter Edbauer, Peter O. Bauer, Karen Overstreet, Lillian M. Daughrity, Leonard Petrucelli, Pamela Desaro, Karen Jansen-West, Kevin F. Bieniek, John D. Fryer, Melissa E. Murray, Amelia Johnston, Rosa Rademakers, Monica Castanedes-Casey, Chris W. Lee, Hiroki Sasaguri, Caroline Stetler, Jeannie Chew, Kevin B. Boylan
المصدر: Science
مصطلحات موضوعية: Pathology, medicine.medical_specialty, Multidisciplinary, Neurodegeneration, Cerebellar Purkinje cell, Biology, medicine.disease, Astrogliosis, C9orf72 Protein, C9orf72, medicine, Amyotrophic lateral sclerosis, Trinucleotide repeat expansion, Engineering sciences. Technology, Frontotemporal dementia
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9340e0776496c05cc423327f356727d5
https://doi.org/10.1126/science.aaa9344 -
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المؤلفون: Michael DeTure, Mary D. Davis, Caroline Stetler, Leonard Petrucelli, Casey Cook, Dennis W. Dickson, Kristyn Scheffel, Matthew Jarpe, Judy Dunmore, Tania F. Gendron, Yari Carlomagno
المصدر: Human Molecular Genetics
مصطلحات موضوعية: Male, Tau protein, Amino Acid Motifs, tau Proteins, Biology, Histone Deacetylase 6, Hydroxamic Acids, Histone Deacetylases, 03 medical and health sciences, Mice, 0302 clinical medicine, Alzheimer Disease, Genetics, medicine, Animals, Humans, Phosphorylation, Molecular Biology, Genetics (clinical), 030304 developmental biology, Aged, Aged, 80 and over, 0303 health sciences, HEK 293 cells, Acetylation, General Medicine, Articles, HDAC6, medicine.disease, 3. Good health, Cell biology, Histone Deacetylase Inhibitors, Chronic traumatic encephalopathy, Disease Models, Animal, HEK293 Cells, Pyrimidines, Biochemistry, biology.protein, Female, Tauopathy, Alzheimer's disease, Protein Multimerization, 030217 neurology & neurosurgery, HeLa Cells
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1c19214d0366262286b0fc1b3361e35
http://europepmc.org/articles/PMC3857946 -
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المصدر: Brain Research. 1462:118-128
مصطلحات موضوعية: Inflammation, Disease, Biology, medicine.disease_cause, Article, Mice, Progranulins, Neurotrophic factors, mental disorders, medicine, Animals, Humans, Dementia, Nerve Growth Factors, Molecular Biology, Wound Healing, Mutation, General Neuroscience, Neurodegeneration, Cancer, Frontotemporal lobar degeneration, medicine.disease, Disease Models, Animal, Intercellular Signaling Peptides and Proteins, Neurology (clinical), Frontotemporal Lobar Degeneration, medicine.symptom, Neuroscience, Signal Transduction, Developmental Biology
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المؤلفون: Christian A. Ross, Mary D. Davis, Sherri M. Biendarra, Marka van Blitterswijk, Mercedes Prudencio, Ralph B. Perkerson, Amelia E Piazza-Johnston, Caroline Stetler, Ranjan Batra, Kevin F. Bieniek, Karen Overstreet, Rosa Rademakers, Kevin B. Boylan, Leonard Petrucelli, Hu Li, Matt Baker, Christopher D. Link, Luc Pregent, Michael DeTure, Melissa E. Murray, Tania F. Gendron, Pamela Desaro, Veronique V. Belzil, Wing C. Lee, Dennis W. Dickson
المصدر: Nature neuroscience
مصطلحات موضوعية: Adult, Polyadenylation, Biology, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, C9orf72, Cerebellum, parasitic diseases, medicine, Humans, Amyotrophic lateral sclerosis, Genetic Association Studies, 030304 developmental biology, Aged, Regulation of gene expression, Genetics, 0303 health sciences, C9orf72 Protein, Heterogeneous-Nuclear Ribonucleoprotein Group F-H, Sequence Analysis, RNA, General Neuroscience, Alternative splicing, Amyotrophic Lateral Sclerosis, C9orf72 Gene, RNA, Proteins, Middle Aged, medicine.disease, Frontal Lobe, Alternative Splicing, Gene Expression Regulation, Human medicine, Neuroscience, 030217 neurology & neurosurgery
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المؤلفون: Jeannie, Chew, Tania F, Gendron, Mercedes, Prudencio, Hiroki, Sasaguri, Yong-Jie, Zhang, Monica, Castanedes-Casey, Chris W, Lee, Karen, Jansen-West, Aishe, Kurti, Melissa E, Murray, Kevin F, Bieniek, Peter O, Bauer, Ena C, Whitelaw, Linda, Rousseau, Jeannette N, Stankowski, Caroline, Stetler, Lillian M, Daughrity, Emilie A, Perkerson, Pamela, Desaro, Amelia, Johnston, Karen, Overstreet, Dieter, Edbauer, Rosa, Rademakers, Kevin B, Boylan, Dennis W, Dickson, John D, Fryer, Leonard, Petrucelli
المصدر: Science / Science now 348(6239), 1151-1154 (2015). doi:10.1126/science.aaa9344
مصطلحات موضوعية: N-glycylalanine, genetics [DNA-Binding Proteins], metabolism [Purkinje Cells], Purkinje Cells, Mice, genetics [Antisocial Personality Disorder], Animals, Humans, pathology [Amyotrophic Lateral Sclerosis], genetics [Frontotemporal Dementia], RNA, Nuclear, Cerebral Cortex, C9orf72 Protein, metabolism [Cerebral Cortex], Amyotrophic Lateral Sclerosis, pathology [Antisocial Personality Disorder], metabolism [Dipeptides], Gene Transfer Techniques, Proteins, Antisocial Personality Disorder, Dipeptides, Dependovirus, genetics [Proteins], pathology [Purkinje Cells], DNA-Binding Proteins, genetics [Amyotrophic Lateral Sclerosis], Disease Models, Animal, HEK293 Cells, metabolism [RNA, Nuclear], Frontotemporal Dementia, ddc:320, pathology [Frontotemporal Dementia], pathology [Cerebral Cortex], glycylproline, C9orf72 protein, human
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6b5a07fe5be13274ebfc8ab2239f3e33
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المؤلفون: Peter O. Bauer, Yong Jie Zhang, Hiroki Sasaguri, Jeannie Chew, Karen Jansen-West, Mercedes Prudencio, Sandra Almeida, Tania F. Gendron, Thomas R. Caulfield, Leonard Petrucelli, William M. Tay, Ian R. A. Mackenzie, Fen-Biao Gao, Wing C. Lee, Caroline Stetler, Ni Cole A. Finch, Rosa Rademakers
المصدر: Human molecular genetics
Human Molecular Geneticsمصطلحات موضوعية: Pyridines, Induced Pluripotent Stem Cells, Haploinsufficiency, Biology, Endocytosis, Progranulins, Cell Line, Tumor, mental disorders, Genetics, Extracellular, medicine, Humans, Lymphocytes, Induced pluripotent stem cell, Molecular Biology, Genetics (clinical), HEK 293 cells, Signal transducing adaptor protein, Genetic Variation, Reproducibility of Results, General Medicine, Frontotemporal lobar degeneration, Articles, medicine.disease, 3. Good health, Cell biology, Adaptor Proteins, Vesicular Transport, Chemistry, HEK293 Cells, Frontotemporal Dementia, Immunology, Intercellular Signaling Peptides and Proteins, Human medicine, Frontotemporal dementia
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa35d7d2f1edf35d8622e7ad2d75882
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المؤلفون: Xiangkun Cao, Ena C. Whitelaw, Jimei Tong, Caroline Stetler, Yong Jie Zhang, Ya Fei Xu, Mercedes Prudencio, Karen Jansen-West, Jaime Hubbard, John Song
المصدر: PLoS ONE
PLoS ONE, Vol 8, Iss 7, p e69864 (2013)مصطلحات موضوعية: Pathology, Mouse, lcsh:Medicine, Biochemistry, Gene Splicing, Motor Neuron Diseases, Mice, 0302 clinical medicine, Neurobiology of Disease and Regeneration, lcsh:Science, Sortilin 1, Animal Management, 0303 health sciences, Multidisciplinary, Homozygote, Agriculture, Neurochemistry, Neurodegenerative Diseases, Frontotemporal lobar degeneration, Animal Models, Cell biology, DNA-Binding Proteins, Nucleic acids, Phenotype, Neurology, RNA splicing, Medicine, Genetic Engineering, Transgenic Animals, Research Article, Biotechnology, Genetically modified mouse, medicine.medical_specialty, Transgene, Dendritic Spines, Down-Regulation, Mice, Transgenic, Biology, Protein Chemistry, 03 medical and health sciences, Model Organisms, Downregulation and upregulation, mental disorders, medicine, Genetics, Animals, Humans, RNA, Messenger, Loss function, 030304 developmental biology, Injections, Intraventricular, Hemizygote, lcsh:R, Alternative splicing, Amyotrophic Lateral Sclerosis, nutritional and metabolic diseases, Proteins, medicine.disease, nervous system diseases, Alternative Splicing, Disease Models, Animal, Animals, Newborn, RNA processing, Synapses, RNA, lcsh:Q, Frontotemporal Lobar Degeneration, Molecular Neuroscience, 030217 neurology & neurosurgery, Neuroscience
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المؤلفون: Tania F. Gendron, Hiroki Sasaguri, Wing C. Lee, Shuyi Cai, Thomas R. Caulfield, Caroline Stetler, Ena C. Whitelaw, Ya Fei Xu, Yong Jie Zhang, Jaime Hubbard, Leonard Petrucelli
المصدر: Human Molecular Genetics
مصطلحات موضوعية: Models, Anatomic, Protein Folding, Protein Conformation, RNA Splicing, Inclusion bodies, 03 medical and health sciences, 0302 clinical medicine, Protein structure, Ubiquitin, mental disorders, Genetics, medicine, Humans, Protein Interaction Domains and Motifs, Molecular Biology, Genetics (clinical), 030304 developmental biology, Inclusion Bodies, 0303 health sciences, biology, Protein Stability, Amyotrophic Lateral Sclerosis, nutritional and metabolic diseases, General Medicine, Articles, medicine.disease, Cell biology, nervous system diseases, Folding (chemistry), DNA-Binding Proteins, Frontotemporal Dementia, RNA splicing, biology.protein, Protein folding, Protein Multimerization, 030217 neurology & neurosurgery, Function (biology), Frontotemporal dementia
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ede2bee0e05175983933e5848f90d6cf
https://pubmed.ncbi.nlm.nih.gov/23575225 -
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المؤلفون: Dennis W. Dickson, Luc Pregent, Tania F. Gendron, Leonard Petrucelli, Mercedes Prudencio, Lillian M. Daughrity, Kevin B. Boylan, Rosa Rademakers, Peter O. Bauer, Caroline Stetler, Tushar Patel, Matt Baker, Veronique V. Belzil, Irene K. Yan
المصدر: Acta neuropathologica
Acta Neuropathologicaمصطلحات موضوعية: Clinical Neurology, Biology, Histone methylation, Pathology and Forensic Medicine, 03 medical and health sciences, Histone H3, Cellular and Molecular Neuroscience, 0302 clinical medicine, C9orf72, Epigenetics, 030304 developmental biology, 0303 health sciences, Original Paper, Epigenetic modification, Repeat expansion, Amyotrophic lateral sclerosis, Molecular biology, 3. Good health, C9orf72 Protein, Histone, DNA methylation, biology.protein, Neurology (clinical), Human medicine, Trinucleotide repeat expansion, Chromatin immunoprecipitation, 030217 neurology & neurosurgery, Frontotemporal dementia