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1دورية أكاديمية
المؤلفون: Caron NS; Centre for Molecular Medicine and Therapeutics, Vancouver, British Columbia, Canada; BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada., Aly AE; Centre for Molecular Medicine and Therapeutics, Vancouver, British Columbia, Canada; BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada., Findlay Black H; Centre for Molecular Medicine and Therapeutics, Vancouver, British Columbia, Canada; BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada., Martin DDO; Centre for Molecular Medicine and Therapeutics, Vancouver, British Columbia, Canada; BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada; Department of Biology, University of Waterloo, Ontario, Canada., Schmidt ME; Centre for Molecular Medicine and Therapeutics, Vancouver, British Columbia, Canada; BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada; Department of Neuroscience, University of British Columbia, Vancouver, British Columbia, Canada., Ko S; Centre for Molecular Medicine and Therapeutics, Vancouver, British Columbia, Canada., Anderson C; Centre for Molecular Medicine and Therapeutics, Vancouver, British Columbia, Canada., Harvey EM; Centre for Molecular Medicine and Therapeutics, Vancouver, British Columbia, Canada., Casal LL; Centre for Molecular Medicine and Therapeutics, Vancouver, British Columbia, Canada., Anderson LM; Centre for Molecular Medicine and Therapeutics, Vancouver, British Columbia, Canada., Rahavi SMR; BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada; Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada., Reid GSD; BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada; Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada., Oda MN; Lipotope, Inc., Fairfield, CA, USA., Stanimirovic D; Human Health Therapeutics Research Centre, National Research Council Canada, Ottawa, Ontario, Canada., Abulrob A; Human Health Therapeutics Research Centre, National Research Council Canada, Ottawa, Ontario, Canada., McBride JL; Division of Neuroscience, Oregon National Primate Research Center, Beaverton, OR, USA; Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR, USA., Leavitt BR; Centre for Molecular Medicine and Therapeutics, Vancouver, British Columbia, Canada; BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada., Hayden MR; Centre for Molecular Medicine and Therapeutics, Vancouver, British Columbia, Canada; BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address: mrh@cmmt.ubc.ca.
المصدر: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2024 Mar; Vol. 367, pp. 27-44. Date of Electronic Publication: 2024 Jan 24.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8607908 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4995 (Electronic) Linking ISSN: 01683659 NLM ISO Abbreviation: J Control Release Subsets: MEDLINE
مواضيع طبية MeSH: Oligonucleotides, Antisense*/therapeutic use , Huntington Disease*/drug therapy , Huntington Disease*/genetics, Mice ; Animals ; Apolipoprotein A-I/genetics ; Oligonucleotides/therapeutic use ; Brain/metabolism ; Huntingtin Protein/genetics ; Huntingtin Protein/metabolism ; Huntingtin Protein/therapeutic use ; Disease Models, Animal
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2دورية أكاديمية
المؤلفون: Duarte F; Laboratory of Cellular and Molecular Neurotherapies, Department of Clinical Neurosciences (DNC).; Laboratory of Cellular and Molecular Neurotherapies (LCMN), Neuroscience Research Center (CRN); Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland., Vachey G; Laboratory of Cellular and Molecular Neurotherapies, Department of Clinical Neurosciences (DNC).; Laboratory of Cellular and Molecular Neurotherapies (LCMN), Neuroscience Research Center (CRN); Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland., Caron NS; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital and Research Institute, University of British Columbia, Vancouver, British Columbia, Canada., Sipion M; Laboratory of Cellular and Molecular Neurotherapies, Department of Clinical Neurosciences (DNC).; Laboratory of Cellular and Molecular Neurotherapies (LCMN), Neuroscience Research Center (CRN); Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland., Rey M; Laboratory of Cellular and Molecular Neurotherapies, Department of Clinical Neurosciences (DNC).; Laboratory of Cellular and Molecular Neurotherapies (LCMN), Neuroscience Research Center (CRN); Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland., Perrier AL; Université Paris-Saclay, CEA, CNRS, Laboratoire des Maladies Neurodégénératives: mécanismes, thérapies, imagerie, Fontenay-aux-Roses, France.; Université Paris-Saclay, CEA, Molecular Imaging Research Center, Fontenay-aux-Roses, France., Hayden MR; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital and Research Institute, University of British Columbia, Vancouver, British Columbia, Canada., Déglon N; Laboratory of Cellular and Molecular Neurotherapies, Department of Clinical Neurosciences (DNC).; Laboratory of Cellular and Molecular Neurotherapies (LCMN), Neuroscience Research Center (CRN); Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland.
المصدر: Human gene therapy [Hum Gene Ther] 2023 Sep; Vol. 34 (17-18), pp. 958-974.
نوع المنشور: Journal Article; Review; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: M.A. Liebert Country of Publication: United States NLM ID: 9008950 Publication Model: Print Cited Medium: Internet ISSN: 1557-7422 (Electronic) Linking ISSN: 10430342 NLM ISO Abbreviation: Hum Gene Ther Subsets: MEDLINE
مواضيع طبية MeSH: Central Nervous System Diseases* , Huntington Disease*/genetics , Huntington Disease*/therapy, Humans ; Animals ; Mice ; RNA, Guide, CRISPR-Cas Systems ; HEK293 Cells ; Exons/genetics ; Alleles ; Central Nervous System
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3دورية أكاديمية
المؤلفون: Aly AE; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, BC V5Z 4H4, Canada., Caron NS; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, BC V5Z 4H4, Canada., Black HF; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, BC V5Z 4H4, Canada., Schmidt ME; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, BC V5Z 4H4, Canada., Anderson C; Centre for Molecular Medicine and Therapeutics, Vancouver, BC V5Z 4H4, Canada., Ko S; Centre for Molecular Medicine and Therapeutics, Vancouver, BC V5Z 4H4, Canada., Baddeley HJE; Centre for Molecular Medicine and Therapeutics, Vancouver, BC V5Z 4H4, Canada., Anderson L; Centre for Molecular Medicine and Therapeutics, Vancouver, BC V5Z 4H4, Canada., Casal LL; Centre for Molecular Medicine and Therapeutics, Vancouver, BC V5Z 4H4, Canada., Rahavi RSM; Michael Cuccione Childhood Cancer Research Program, British Columbia Children's a Hospital Research Institute, Vancouver, BC V5Z 4H4, Canada., Martin DDO; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, BC V5Z 4H4, Canada; Department of Biology, University of Waterloo, Ontario, Canada., Hayden MR; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, BC V5Z 4H4, Canada. Electronic address: mrh@cmmt.ubc.ca.
المصدر: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2023 Aug; Vol. 360, pp. 913-927. Date of Electronic Publication: 2023 Jul 27.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8607908 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4995 (Electronic) Linking ISSN: 01683659 NLM ISO Abbreviation: J Control Release Subsets: MEDLINE
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4دورية أكاديمية
المؤلفون: Joachimiak P; Department of Medical Biotechnology, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14, 61-704, Poznan, Poland., Ciesiołka A; Department of Medical Biotechnology, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14, 61-704, Poznan, Poland., Kozłowska E; Department of Medical Biotechnology, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14, 61-704, Poznan, Poland., Świtoński PM; Department of Medical Biotechnology, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14, 61-704, Poznan, Poland., Figura G; Department of Medical Biotechnology, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14, 61-704, Poznan, Poland., Ciołak A; Department of Medical Biotechnology, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14, 61-704, Poznan, Poland., Adamek G; Department of Medical Biotechnology, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14, 61-704, Poznan, Poland., Surdyka M; Department of Molecular Neurobiology, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14, 61-704, Poznan, Poland., Kalinowska-Pośka Ż; Department of Molecular Neurobiology, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14, 61-704, Poznan, Poland., Figiel M; Department of Molecular Neurobiology, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14, 61-704, Poznan, Poland., Caron NS; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, BC, V5Z 4H4, Canada., Hayden MR; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, BC, V5Z 4H4, Canada., Fiszer A; Department of Medical Biotechnology, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14, 61-704, Poznan, Poland. agnieszka.fiszer@ibch.poznan.pl.
المصدر: BMC biology [BMC Biol] 2023 Feb 01; Vol. 21 (1), pp. 17. Date of Electronic Publication: 2023 Feb 01.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101190720 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-7007 (Electronic) Linking ISSN: 17417007 NLM ISO Abbreviation: BMC Biol Subsets: MEDLINE
مواضيع طبية MeSH: Trinucleotide Repeat Expansion*/genetics , Repressor Proteins*/genetics, Humans ; Mice ; Animals ; Alleles ; Ataxin-3/genetics ; Ataxin-3/metabolism ; Reproducibility of Results ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Huntingtin Protein/genetics
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5دورية أكاديمية
المؤلفون: Caron NS; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, BC V5Z 4H4, Canada., Haqqani AS; Human Health Therapeutics Research Centre, National Research Council of Canada, Ottawa, ON K1A 0R6, Canada., Sandhu A; BC Children's Hospital Research Institute, University of British Columbia, Vancouver, BC V5Z 4H4, Canada., Aly AE; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, BC V5Z 4H4, Canada., Findlay Black H; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, BC V5Z 4H4, Canada., Bone JN; BC Children's Hospital Research Institute, University of British Columbia, Vancouver, BC V5Z 4H4, Canada., McBride JL; Division of Neuroscience, Oregon National Primate Research Center, Beaverton, OR 97006, USA.; Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239, USA., Abulrob A; Human Health Therapeutics Research Centre, National Research Council of Canada, Ottawa, ON K1A 0R6, Canada., Stanimirovic D; Human Health Therapeutics Research Centre, National Research Council of Canada, Ottawa, ON K1A 0R6, Canada., Leavitt BR; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, BC V5Z 4H4, Canada., Hayden MR; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, BC V5Z 4H4, Canada.
المصدر: Brain communications [Brain Commun] 2022 Nov 25; Vol. 4 (6), pp. fcac309. Date of Electronic Publication: 2022 Nov 25 (Print Publication: 2022).
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 101755125 Publication Model: eCollection Cited Medium: Internet ISSN: 2632-1297 (Electronic) Linking ISSN: 26321297 NLM ISO Abbreviation: Brain Commun Subsets: PubMed not MEDLINE
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6دورية أكاديمية
المؤلفون: Caron NS; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, BC V5Z 4H4, Canada. Electronic address: ncaron@cmmt.ubc.ca., Banos R; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL 32827, USA. Electronic address: raul.banos@ucf.edu., Aly AE; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, BC V5Z 4H4, Canada. Electronic address: aealy@cmmt.ubc.ca., Xie Y; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL 32827, USA. Electronic address: yuanyun.xie@ucf.edu., Ko S; Centre for Molecular Medicine and Therapeutics, Vancouver, BC V5Z 4H4, Canada. Electronic address: yko@cmmt.ubc.ca., Potluri N; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL 32827, USA. Electronic address: nalini.potluri@ucf.edu., Anderson C; Centre for Molecular Medicine and Therapeutics, Vancouver, BC V5Z 4H4, Canada. Electronic address: canderson@cmmt.ubc.ca., Black HF; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, BC V5Z 4H4, Canada. Electronic address: hfindlayblack@cmmt.ubc.ca., Anderson LM; Centre for Molecular Medicine and Therapeutics, Vancouver, BC V5Z 4H4, Canada. Electronic address: landerson@cmmt.ubc.ca., Gordon B; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL 32827, USA. Electronic address: benjamin.gordon@ucf.edu., Southwell AL; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL 32827, USA. Electronic address: amber.southwell@ucf.edu., Hayden MR; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, BC V5Z 4H4, Canada. Electronic address: mrh@cmmt.ubc.ca.
المصدر: Neurobiology of disease [Neurobiol Dis] 2022 May; Vol. 166, pp. 105652. Date of Electronic Publication: 2022 Feb 07.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-953X (Electronic) Linking ISSN: 09699961 NLM ISO Abbreviation: Neurobiol Dis Subsets: MEDLINE
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7دورية أكاديمية
المؤلفون: Nath S; Department of Biochemistry and Biomedical Sciences, Michael G. DeGroote School of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada.; Department of Ophthalmology and Visual Sciences, McGill University, Montréal, QC, Canada., Caron NS; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada., May L; Division of Neurology, Department of Medicine and Department of Pediatrics, Michael G. DeGroote School of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada., Gluscencova OB; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.; Program in Developmental and Stem Cell Biology, Hospital for Sick Children, Peter Gilgan Centre for Research and Learning, Toronto, ON, Canada., Kolesar J; Vascular Medicine Institute, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Brady L; Genetic Counselling Program, Hamilton Health Sciences, Hamilton, ON, Canada. bradyla@hhsc.ca., Kaufman BA; Vascular Medicine Institute, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Boulianne GL; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.; Program in Developmental and Stem Cell Biology, Hospital for Sick Children, Peter Gilgan Centre for Research and Learning, Toronto, ON, Canada., Rodriguez AR; Division of Ophthalmology, Department of Surgery, Michael G. DeGroote School of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada., Tarnopolsky MA; Division of Neurology, Department of Medicine and Department of Pediatrics, Michael G. DeGroote School of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada., Truant R; Department of Biochemistry and Biomedical Sciences, Michael G. DeGroote School of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada. truantr@mcmaster.ca.
المصدر: Human genome variation [Hum Genome Var] 2022 Apr 14; Vol. 9 (1), pp. 10. Date of Electronic Publication: 2022 Apr 14.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101652445 Publication Model: Electronic Cited Medium: Print ISSN: 2054-345X (Print) Linking ISSN: 2054345X NLM ISO Abbreviation: Hum Genome Var Subsets: PubMed not MEDLINE
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8دورية أكاديمية
المؤلفون: Lemarié FL; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, Canada., Caron NS; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, Canada., Sanders SS; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, Canada; Department of Molecular and Cellular Biology, University of Guelph, Guelph, Canada., Schmidt ME; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, Canada., Nguyen YTN; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, Canada., Ko S; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, Canada., Xu X; Department of Neurology and Stroke Center, The First Affiliated Hospital, Jinan University, Guangzhou, China; Translational Laboratory in Genetic Medicine, Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Pouladi MA; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, Canada; Translational Laboratory in Genetic Medicine, Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Martin DDO; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, Canada; Department of Biology, University of Waterloo, Waterloo, Canada., Hayden MR; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, Canada. Electronic address: mrh@cmmt.ubc.ca.
المصدر: Neurobiology of disease [Neurobiol Dis] 2021 Oct; Vol. 158, pp. 105479. Date of Electronic Publication: 2021 Aug 12.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-953X (Electronic) Linking ISSN: 09699961 NLM ISO Abbreviation: Neurobiol Dis Subsets: MEDLINE
مواضيع طبية MeSH: Huntingtin Protein/*genetics , Huntingtin Protein/*toxicity , Lipoylation/*drug effects , Lipoylation/*genetics, Acyltransferases/genetics ; Adaptor Proteins, Signal Transducing/genetics ; Animals ; COS Cells ; Cell Line ; Chlorocebus aethiops ; Cysteine/chemistry ; Enzyme Inhibitors/pharmacology ; Enzyme Inhibitors/therapeutic use ; Female ; Humans ; Lymphocytes/drug effects ; Lymphocytes/metabolism ; Male ; Mice ; Mutation ; Nerve Tissue Proteins/genetics ; Neurons/drug effects ; Neurons/metabolism ; Rats
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9دورية أكاديمية
المؤلفون: Caron NS; Centre for Molecular Medicine and Therapeutics, British Columbia Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia V5Z 4H4, Canada., Banos R; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida 32828., Yanick C; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida 32828., Aly AE; Centre for Molecular Medicine and Therapeutics, British Columbia Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia V5Z 4H4, Canada., Byrne LM; UCL Huntington's Disease Centre, UCL Queen Square Institute of Neurology, University College London, London, WC1N 3BG, United Kingdom., Smith ED; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida 32828., Xie Y; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida 32828., Smith SEP; Seattle Children's Research Institute, Center for Integrative Brain Research, Seattle, Washington 98101., Potluri N; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida 32828., Findlay Black H; Centre for Molecular Medicine and Therapeutics, British Columbia Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia V5Z 4H4, Canada., Casal L; Centre for Molecular Medicine and Therapeutics, Vancouver, British Columbia V5Z 4H4, Canada., Ko S; Centre for Molecular Medicine and Therapeutics, Vancouver, British Columbia V5Z 4H4, Canada., Cheung D; Centre for Molecular Medicine and Therapeutics, Vancouver, British Columbia V5Z 4H4, Canada., Kim H; Department of Biological Sciences, KAIST, Daejeon, Korea, 34141., Seong IS; Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts 02114., Wild EJ; UCL Huntington's Disease Centre, UCL Queen Square Institute of Neurology, University College London, London, WC1N 3BG, United Kingdom., Song JJ; Department of Biological Sciences, KAIST, Daejeon, Korea, 34141., Hayden MR; Centre for Molecular Medicine and Therapeutics, British Columbia Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia V5Z 4H4, Canada amber.southwell@ucf.edu mrh@cmmt.ubc.ca., Southwell AL; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida 32828 amber.southwell@ucf.edu mrh@cmmt.ubc.ca.
المصدر: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2021 Jan 27; Vol. 41 (4), pp. 780-796. Date of Electronic Publication: 2020 Dec 11.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE
مواضيع طبية MeSH: Brain Chemistry*, Huntingtin Protein/*cerebrospinal fluid , Huntington Disease/*cerebrospinal fluid, Animals ; Astrocytes/metabolism ; Biomarkers/cerebrospinal fluid ; Female ; Glymphatic System/metabolism ; Humans ; Huntingtin Protein/genetics ; Huntington Disease/genetics ; Male ; Mice ; Mice, Transgenic ; Mutation ; Neurons/metabolism ; Trinucleotide Repeat Expansion
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10دورية أكاديمية
المؤلفون: Caron NS; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada., Anderson C; Centre for Molecular Medicine and Therapeutics, Vancouver, BC, Canada., Black HF; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada., Sanders SS; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada., Lemarié FL; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada., Doty CN; Centre for Molecular Medicine and Therapeutics, Vancouver, BC, Canada., Hayden MR; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada.
المصدر: Journal of Huntington's disease [J Huntingtons Dis] 2021; Vol. 10 (3), pp. 355-365.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: IOS Press Country of Publication: Netherlands NLM ID: 101589965 Publication Model: Print Cited Medium: Internet ISSN: 1879-6400 (Electronic) Linking ISSN: 18796397 NLM ISO Abbreviation: J Huntingtons Dis Subsets: MEDLINE
مواضيع طبية MeSH: Huntington Disease*/genetics, Alleles ; Animals ; Humans ; Huntingtin Protein/genetics ; Immunoblotting ; Mice