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1دورية أكاديمية
المؤلفون: Caryn Hampton, Raymond Rosa, Daphne Szeto, Gail Forrest, Barry Campbell, Richard Kennan, Shubing Wang, Chin-Hu Huang, Loise Gichuru, Xiaoli Ping, Xiaolan Shen, Kersten Small, Jeffrey Madwed, Joseph J Lynch
المصدر: SAGE Open Medicine, Vol 5 (2017)
مصطلحات موضوعية: Medicine (General), R5-920
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2050-3121
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2
المؤلفون: Xin Gu, Brande Thomas-Fowlkes, Dorothy Levorse, Harry R. Chobanian, Timothy Cutarelli, Alexander Pasternak, Adam B. Weinglass, Ian W. Davies, Martin Koehler, Michael Margulis, Fa-Xiang Ding, Joel B. Yudkovitz, Jinlong Jiang, Haifeng Tang, Lee-Yuh Pai, Barbara Pio, Shuzhi Dong, Mengwei Hu, Kathleen A. Sullivan, Jack Gibson, Thomas Bateman, Koppara Samuel, Xiaoyan Zhou, Caryn Hampton, Reynalda deJesus, Kevin Houle, Emma R. Parmee
المصدر: Journal of medicinal chemistry. 64(11)
مصطلحات موضوعية: Male, medicine.medical_treatment, Diuresis, Action Potentials, Blood Pressure, Pharmacology, 01 natural sciences, Piperazines, Natriuresis, Excretion, 03 medical and health sciences, Dogs, Rats, Inbred SHR, Drug Discovery, medicine, Potassium Channel Blockers, Animals, Humans, Dosing, Potassium Channels, Inwardly Rectifying, Diuretics, 030304 developmental biology, Benzofurans, 0303 health sciences, Chemistry, Furosemide, Haplorhini, medicine.disease, 0104 chemical sciences, Rats, 010404 medicinal & biomolecular chemistry, Heart failure, ROMK, Potassium, Molecular Medicine, Natriuretic Agents, Diuretic, medicine.drug, Half-Life
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3
المؤلفون: Haifeng Tang, Zack Zhiqiang Guo, Lee-Yuh Pai, Adam B. Weinglass, Xin Gu, Shuzhi Dong, Alexander Pasternak, Yang Yu, Kathleen A. Sullivan, Mengwei Hu, Kelsey VanGelder, Gloria J. Zingaro, Sophie Roy, Jessica Liu, Qinghong Fu, Birgit T. Priest, Michael Margulis, Brande Thomas-Fowlkes, Pierre Morissette, Robin E. Haimbach, Zhicai Wu, Juliann Ehrhart, Karen Owens, Caryn Hampton, Zhi-Cai Shi, Jessica Frie, Ron Ferguson, Shiyao Xu, Vincent Tong
المصدر: Bioorganic & Medicinal Chemistry Letters. 27:2559-2566
مصطلحات موضوعية: 0301 basic medicine, ERG1 Potassium Channel, Scaffold, Clinical Biochemistry, hERG, Pharmaceutical Science, Pharmacology, Biochemistry, Structure-Activity Relationship, 03 medical and health sciences, Dogs, 0302 clinical medicine, Thiadiazoles, In vivo, Rats, Inbred SHR, Drug Discovery, Potassium Channel Blockers, medicine, Animals, Structure–activity relationship, Spiro Compounds, Potassium Channels, Inwardly Rectifying, Molecular Biology, biology, Chemistry, Organic Chemistry, Potassium channel blocker, Rats, Disease Models, Animal, Pyrimidines, 030104 developmental biology, 030220 oncology & carcinogenesis, Hypertension, ROMK, biology.protein, Molecular Medicine, Pharmacophore, Half-Life, medicine.drug
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4
المؤلفون: Kersten M. Small, Caryn Hampton, Loise Gichuru, Joseph J. Lynch, Xiaoli Ping, Ray Rosa, Richard Kennan, Jeffrey B. Madwed, Xiaolan Shen, Barry R. Campbell
المصدر: Journal of Pharmacological and Toxicological Methods. 84:93-101
مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Diastole, Hemodynamics, 030204 cardiovascular system & hematology, Toxicology, Ventricular Function, Left, Constriction, Mice, Random Allocation, 03 medical and health sciences, 0302 clinical medicine, Predictive Value of Tests, Internal medicine, medicine, Animals, Heart Failure, Pharmacology, Pressure overload, Ejection fraction, Receiver operating characteristic, business.industry, medicine.disease, Mice, Inbred C57BL, Disease Models, Animal, Stenosis, 030104 developmental biology, Echocardiography, Heart failure, Cardiology, Hypertrophy, Left Ventricular, business
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5
المؤلفون: Lee-Yuh Pai, Aaron Corona, Harry R. Chobanian, John P. Felix, Matthew J. Clements, Karen Owens, Haifeng Tang, Brande Thomas-Fowlkes, Kathleen A. Sullivan, Alexander Pasternak, Caryn Hampton, Jessica Frie, Vincent Tong, Ron Ferguson, Jessica Liu, Birgit T. Priest, Barbara Pio, Yan Guo, Elizabeth Joshi, Nardos Teumelsan, Ling Xu, Martin Köhler, Joseph M. Metzger, Zach Guo, Kevin M. Maloney
المصدر: Bioorganic & Medicinal Chemistry Letters. 27:1109-1114
مصطلحات موضوعية: 0301 basic medicine, Stereochemistry, medicine.medical_treatment, Clinical Biochemistry, hERG, Pharmaceutical Science, Diuresis, Biochemistry, Natriuresis, Sulfone, 03 medical and health sciences, chemistry.chemical_compound, Heterocyclic Compounds, Rats, Inbred SHR, Drug Discovery, medicine, Animals, Moiety, Organic chemistry, Sulfones, Enzyme Inhibitors, Potassium Channels, Inwardly Rectifying, Diuretics, Molecular Biology, biology, Chemistry, Organic Chemistry, Rats, 030104 developmental biology, Drug Design, ROMK, biology.protein, Molecular Medicine, Diuretic, Selectivity
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6
المؤلفون: Shawn P. Walsh, Lee-Yuh Pai, Yuping Zhu, John P. Felix, Caryn Hampton, Xiaoyan Zhou, Melba Hernandez, Brande Thomas-Fowlkes, Richard M. Brochu, Nardos Teumelsan, Gregory J. Kaczorowski, Emma R. Parmee, Maria L. Garcia, Alexander Pasternak, Jinlong Jiang, Sookhee Ha, Sophie Roy, Kathleen A. Sullivan, Haifeng Tang, Lihu Yang, Karen Owens, Reynalda K. de Jesus, Xin Gu, Birgit T. Priest, Barbara Pio, Fa-Xiang Ding, Andrew M. Swensen, Magdalena Alonso-Galicia, Aurash Shahripour, Juliann Ehrhart, Timothy Bailey
المصدر: Bioorganic & Medicinal Chemistry Letters. 26:5695-5702
مصطلحات موضوعية: 0301 basic medicine, QTC PROLONGATION, Clinical Biochemistry, hERG, Pharmaceutical Science, Pharmacology, Biochemistry, Dog model, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, Dogs, 0302 clinical medicine, Transcriptional Regulator ERG, Pharmacokinetics, In vivo, Oxazines, Drug Discovery, Animals, Humans, Potassium Channels, Inwardly Rectifying, Molecular Biology, Heart Failure, biology, Chemistry, Organic Chemistry, Macaca mulatta, Small molecule, Diuresis, Piperazine, 030104 developmental biology, 030220 oncology & carcinogenesis, Hypertension, ROMK, biology.protein, Molecular Medicine
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7
المؤلفون: Michael J. Forrest, John P. Felix, Lee-Yuh Pai, Melba Hernandez, Yuping Zhu, Aaron Corona, Joseph M. Metzger, Gregory J. Kaczorowski, Nardos Teumelsan, Lihu Yang, Karen Owens, Timothy Bailey, Caryn Hampton, Vincent Tong, Alexander Pasternak, Brande Thomas-Fowlkes, Shawn P. Walsh, Emma R. Parmee, Haifeng Tang, Richard M. Brochu, Maria L. Garcia, Xiaoyan Zhou, Magdalena Alonso-Galicia, Sophie Roy, Birgit T. Priest, Andrew M. Swensen, Aurash Shahripour
المصدر: ACS Medicinal Chemistry Letters. 7:697-701
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Kidney, biology, Chemistry, Organic Chemistry, hERG, Diuresis, Nephron, Pharmacology, Biochemistry, Natriuresis, 03 medical and health sciences, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, Internal medicine, Drug Discovery, medicine, biology.protein, Loop of Henle, ROMK, Thiazide, medicine.drug
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8
المؤلفون: Lee-Yuh Pai, Yuping Zhu, Richard Visconti, Xiaoyan Zhou, John P. Felix, Melba Hernandez, Jing Chen, Michael Margulis, Nardos Teumelsan, Sophie Roy, Kathleen A. Sullivan, Jessica Liu, Joseph M. Metzger, Aaron Corona, Gregory J. Kaczorowski, Maria L. Garcia, Lihu Yang, Shawn P. Walsh, Birgit T. Priest, Alexander Pasternak, Caryn Hampton, Emma R. Parmee, Vincent Tong, Brande Thomas-Fowlkes, Haifeng Tang, Magdalena Alonso-Galicia, Kashmira Shah, Michael J. Forrest, Richard M. Brochu, Ross Bentley, Sookhee Ha, Karen Owens, Aurash Shahripour, Andrew M. Swensen, Jessica Frie, Adam B. Weinglass, Timothy Bailey
المصدر: ACS Medicinal Chemistry Letters. 6:747-752
مصطلحات موضوعية: Pharmacokinetics, Chemistry, Pharmacodynamics, Organic Chemistry, Drug Discovery, ROMK, Pharmacology, Biochemistry
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9
المؤلفون: Yan Yan, Richard M. Brochu, Maria L. Garcia, Lihu Yang, Sophie Roy, Gregory J. Kaczorowski, Reynald K. de Jesus, Birgit T. Priest, Xiaoyan Zhou, Lee-Yuh Pai, Shawn P. Walsh, Yuping Zhu, Karen Owens, Caryn Hampton, Timothy Bailey, Andrew M. Swensen, Brande Thomas-Fowlkes, Magdalena Alonso-Galicia, John P. Felix, Melba Hernandez, Alexander Pasternak, Haifeng Tang
المصدر: Bioorganic & Medicinal Chemistry Letters. 23:5829-5832
مصطلحات موضوعية: Natriuretic Agents, Isobenzofuran, Stereochemistry, Clinical Biochemistry, hERG, Tetrazoles, Pharmaceutical Science, Biochemistry, Rats, Sprague-Dawley, chemistry.chemical_compound, In vivo, Drug Discovery, Animals, Humans, Potassium Channels, Inwardly Rectifying, Molecular Biology, Benzofurans, biology, Chemistry, Organic Chemistry, Small molecule, Ether-A-Go-Go Potassium Channels, Diuresis, Rats, ROMK, biology.protein, Molecular Medicine
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10
المؤلفون: Haifeng Tang, Kashmira Shah, Maria L. Garcia, Alexander Pasternak, Magdalena Alonso-Galicia, Brande Thomas-Fowlkes, Cordelia Rasa, Joseph M. Metzger, Sophie Roy, Lee-Yuh Pai, Jessica Liu, Olga Price, Vince Tong, Birgit T. Priest, Gregory J. Kaczorowski, James D. Ormes, Charles Gill, Aaron Corona, John P. Felix, Jianying Xiao, Kathleen A. Sullivan, Karen Owens, Caryn Hampton, Xiaoyan Zhou, Martin Köhler
المصدر: The Journal of pharmacology and experimental therapeutics. 359(1)
مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_specialty, Diuresis, Tetrazoles, Blood Pressure, Pharmacology, Bartter syndrome, Piperazines, Natriuresis, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Dogs, Internal medicine, medicine, Potassium Channel Blockers, Animals, Humans, Potassium Channels, Inwardly Rectifying, Benzofurans, Aldosterone, Dose-Response Relationship, Drug, Chemistry, Biphenyl Compounds, Bartter Syndrome, Potassium channel blocker, Drug Synergism, medicine.disease, Rats, Bartter's syndrome, 030104 developmental biology, Endocrinology, HEK293 Cells, Hydrochlorothiazide, Phenotype, 030220 oncology & carcinogenesis, Kaliuresis, ROMK, Molecular Medicine, Benzimidazoles, Female, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6a55d5d0f3672edd7db9d025d76d0fd
https://pubmed.ncbi.nlm.nih.gov/27432892