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المؤلفون: Scott B. Snapper, Veit Hornung, Hans Clevers, Moritz M. Gaidt, Nadine Yazbeck, Fabian Hauck, Rima Hanna-Wakim, Katja Lammens, Philip Bufler, Yue Li, Aleixo M. Muise, Maryam Ghalandary, Birgitta E. Michels, Anna S. Lehle, Henner F. Farin, Raffaele Conca, Thomas Magg, Batia Weiss, Yanshan Liu, Sibylle Koletzko, Atar Lev, Neil Warner, Olaf Groß, Daniel Kotlarz, Amos J. Simon, Christoph Walz, Christoph Klein, Sebastian Hollizeck, Benjamin Marquardt, Raz Somech, Dror S. Shouval, Meino Rohlfs
المساهمون: Hubrecht Institute for Developmental Biology and Stem Cell Research
المصدر: Gastroenterology, 156(1), 275-278. W.B. Saunders Ltd
Gastroenterology, 156(1), 275. W.B. Saunders Ltdمصطلحات موضوعية: 0301 basic medicine, Heredity, Inflammasomes, Biopsy, Ulcerative/genetics, Apoptosis, Lymphocytes/immunology, Endoscopy, Gastrointestinal, Mice, 0302 clinical medicine, Lymphocytes, Age of Onset, Colitis, Ulcerative/genetics, Autoimmune Lymphoproliferative Syndrome/genetics, Mice, Knockout, Caspase 8, Gastroenterology, Inflammasome, Colitis, Acquired immune system, Intestines, Phenotype, 030211 gastroenterology & hepatology, Tumor necrosis factor alpha, Inflammation Mediators, medicine.symptom, medicine.drug, Intestines/immunology, Gastrointestinal, Inflammasomes/immunology, Caspase 8/genetics, Knockout, Necroptosis, Inflammation, 03 medical and health sciences, Germline mutation, Immune system, Immunity, medicine, Animals, Humans, Genetic Predisposition to Disease, Inflammation Mediators/immunology, Hepatology, business.industry, Autoimmune Lymphoproliferative Syndrome, Epithelial Cells/immunology, Epithelial Cells, Endoscopy, 030104 developmental biology, Mutation, Cancer research, Colitis, Ulcerative, business
وصف الملف: image/pdf; text/plain
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المساهمون: Chemical Biology, Biomedical Engineering
المصدر: ChemBioChem, 19(23), 2490-2494. Wiley-VCH Verlag
Chembiochemمصطلحات موضوعية: Bridged-Ring Compounds, Stereochemistry, Caspase 8/genetics, Dimer, Mutant, Supramolecular chemistry, protein assembly, 010402 general chemistry, 01 natural sciences, Biochemistry, Catalysis, supramolecular chemistry, Catalysis/drug effects, chemistry.chemical_compound, Enzyme Reactivators, Enzyme Reactivators/chemistry, Imidazoles/chemistry, Humans, Point Mutation, Bridged-Ring Compounds/chemistry, Protein Dimerization, Molecular Biology, Caspase 8, Full Paper, biology, 010405 organic chemistry, Organic Chemistry, Imidazoles, Substrate (chemistry), Active site, protein engineering, Protein engineering, Full Papers, Protein Multimerization/drug effects, 0104 chemical sciences, Monomer, caspases, chemistry, cucurbit[8]uril, biology.protein, Molecular Medicine, Protein Multimerization
وصف الملف: application/pdf
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المؤلفون: Dondelinger, Yves, Delanghe, Tom, Priem, Dario, Wynosky-Dolfi, Meghan A, Sorobetea, Daniel, Rojas-Rivera, Diego, Giansanti, Piero, Roelandt, Ria, Gropengiesser, Julia, Ruckdeschel, Klaus, Savvides, Savvas N, Heck, Albert J R, Vandenabeele, Peter, Brodsky, Igor E, Bertrand, Mathieu J M, Sub Biomol.Mass Spectrometry & Proteom., Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics
المساهمون: Sub Biomol.Mass Spectrometry & Proteom., Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics
المصدر: Nature Communications, 10(1). Nature Publishing Group
NATURE COMMUNICATIONS
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)مصطلحات موضوعية: 0301 basic medicine, NF-KAPPA-B, General Physics and Astronomy, Apoptosis, 02 engineering and technology, IκB kinase, environment and public health, ACTIVATION, PATHWAY, Mice, Models, OUTER PROTEIN-P, Serine, Medicine and Health Sciences, Phosphorylation, lcsh:Science, Caspase 8, Multidisciplinary, Chemistry, Kinase, NECROSIS, I-kappa B Kinase/metabolism, 021001 nanoscience & nanotechnology, Yersinia, 3. Good health, Cell biology, ddc, I-kappa B Kinase, Immunological, Receptor-Interacting Protein Serine-Threonine Kinases, 0210 nano-technology, Serine/chemistry, Programmed cell death, Yersinia Infections, Necroptosis, Science, Caspase 8/genetics, BETA, Receptor-Interacting Protein Serine-Threonine Kinases/chemistry, General Biochemistry, Genetics and Molecular Biology, Article, DOMAIN KINASE, Cell Line, 03 medical and health sciences, RIPK1, Animals, Kinase activity, NECROPTOSIS, Yersinia Infections/immunology, COMPLEX, Immunity, Models, Immunological, Biology and Life Sciences, General Chemistry, Immunity/physiology, enzymes and coenzymes (carbohydrates), 030104 developmental biology, lcsh:Q
وصف الملف: image/pdf; application/pdf
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المؤلفون: Janssens, A. C., Gonzalez-Zuloeta Ladd, A. M., Lopez-Leon, S., Ioannidis, J. P., Oostra, B. A., Khoury, M. J., van Duijn, C. M.
مصطلحات موضوعية: Gene Frequency, Genotype, Breast Neoplasms/*genetics/pathology, Risk Factors, Caspase 8/genetics, Odds Ratio, Humans, Female, Genetic Predisposition to Disease/*genetics, Polymorphism, Genetic, Polymorphism, Single Nucleotide
URL الوصول: https://explore.openaire.eu/search/publication?articleId=od_____10561::2fd9aeec2379eefbbf634814e884c1fa
http://olympias.lib.uoi.gr/jspui/handle/123456789/23907 -
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المؤلفون: R. Audo, Jacques Morel, Bernard Combe, B Coulet, Michael Hahne
المساهمون: Institut de Génétique Moléculaire de Montpellier (IGMM), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)
المصدر: Cell Death and Differentiation
Cell Death and Differentiation, Nature Publishing Group, 2009, 16 (9), pp.1227--37. ⟨10.1038/cdd.2009.38⟩مصطلحات موضوعية: MAPK/ERK pathway, Cyclin-Dependent Kinase Inhibitor p21, Small Interfering/metabolism Recombinant Proteins/pharmacology Signal Transduction Synovial Membrane/cytology TNF-Related Apoptosis-Inducing Ligand/*pharmacology p38 Mitogen-Activated Protein Kinases/metabolism, p38 mitogen-activated protein kinases, Rheumatoid/enzymology/metabolism Caspase 3/genetics/*metabolism Caspase 8/genetics/*metabolism Cell Proliferation Cells, Antineoplastic Agents, Apoptosis, Caspase 8, p38 Mitogen-Activated Protein Kinases, Arthritis, Rheumatoid, TNF-Related Apoptosis-Inducing Ligand, 03 medical and health sciences, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, Humans, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, RNA, Small Interfering, Extracellular Signal-Regulated MAP Kinases, Molecular Biology, Caspase, Cells, Cultured, 030304 developmental biology, Cell Proliferation, 0303 health sciences, biology, Caspase 3, Synovial Membrane, Cell Biology, Fibroblasts, Recombinant Proteins, 3. Good health, XIAP, Cultured Cyclin-Dependent Kinase Inhibitor p21/metabolism Cyclin-Dependent Kinase Inhibitor p27/metabolism Extracellular Signal-Regulated MAP Kinases/metabolism Fibroblasts/drug effects/enzymology/metabolism Humans Phosphatidylinositol 3-Kinases/metabolism RNA, Antineoplastic Agents/*pharmacology Apoptosis Arthritis, 030220 oncology & carcinogenesis, Cancer cell, Immunology, Cancer research, biology.protein, Tumor necrosis factor alpha, Cyclin-Dependent Kinase Inhibitor p27, Signal Transduction
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المؤلفون: Katia Balmas Bourloud, Aurélie Coulon, Nicole Gross, Margot Thome, Annick Mühlethaler-Mottet, Julie Liberman, Katya Nardou, Marjorie Flahaut
المصدر: Cell Death and Disease, vol. 2, pp. e125
Cell Death & Disease
Cell death & diseaseمصطلحات موضوعية: Cancer Research, Cell type, Amino Acid Motifs, Immunology, caspase-10, TRAIL, Caspase 8, caspase-8, Fas ligand, TNF-Related Apoptosis-Inducing Ligand, neuroblastoma, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Cell Line, Tumor, Humans, Gene silencing, Caspase 10, Caspase, 030304 developmental biology, 0303 health sciences, biology, Tumor Necrosis Factor-alpha, Apoptosis, Caspase 10/chemistry, Caspase 10/genetics, Caspase 8/genetics, Caspase 8/metabolism, Isoenzymes/genetics, Isoenzymes/metabolism, Neuroblastoma/enzymology, Neuroblastoma/genetics, Receptors, Death Domain/genetics, Receptors, Death Domain/metabolism, Receptors, TNF-Related Apoptosis-Inducing Ligand/metabolism, TNF-Related Apoptosis-Inducing Ligand/metabolism, Tumor Necrosis Factor-alpha/metabolism, apoptosis, Receptors, Death Domain, Cell Biology, Cell biology, Isoenzymes, Receptors, TNF-Related Apoptosis-Inducing Ligand, 030220 oncology & carcinogenesis, caspase-10, caspase-8, apoptosis, TRAIL, neuroblastoma, biology.protein, Original Article, Tumor necrosis factor alpha
وصف الملف: application/pdf
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المؤلفون: Benjamin, Demarco, James P, Grayczyk, Elisabet, Bjanes, Didier, Le Roy, Wulf, Tonnus, Charles-Antoine, Assenmacher, Enrico, Radaelli, Timothée, Fettrelet, Vanessa, Mack, Andreas, Linkermann, Thierry, Roger, Igor E, Brodsky, Kaiwen W, Chen, Petr, Broz
المصدر: Science advances, vol. 6, no. 47, pp. eabc3465
Science Advancesمصطلحات موضوعية: Caspase 8, Anti-Infective Agents, Tumor Necrosis Factor-alpha, fungi, Intracellular Signaling Peptides and Proteins, food and beverages, SciAdv r-articles, Cell Biology, Caspase 8/genetics, Intracellular Signaling Peptides and Proteins/genetics, Intracellular Signaling Peptides and Proteins/metabolism, Phosphate-Binding Proteins/genetics, Phosphate-Binding Proteins/metabolism, Tumor Necrosis Factor-alpha/metabolism, Tumor Necrosis Factor-alpha/pharmacology, Phosphate-Binding Proteins, Biochemistry, Research Articles, Research Article
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::42bf3c3bdb34166c43f87daf589aeb3b
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8مورد إلكتروني
المصدر: Gastroenterology vol.156 (2019) nr.1 p.275-278 [ISSN 0016-5085]
مصطلحات الفهرس: Age of Onset, Animals, Apoptosis, Autoimmune Lymphoproliferative Syndrome/genetics, Biopsy, Caspase 8/genetics, Colitis, Ulcerative/genetics, Endoscopy, Gastrointestinal, Epithelial Cells/immunology, Genetic Predisposition to Disease, Heredity, Humans, Inflammasomes/immunology, Inflammation Mediators/immunology, Intestines/immunology, Lymphocytes/immunology, Mice, Knockout, Mutation, Phenotype, Artikel, Article
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9مورد إلكتروني
المصدر: Gastroenterology vol.156 (2019) nr.1 p.275-278 [ISSN 0016-5085]
مصطلحات الفهرس: Age of Onset, Animals, Apoptosis, Autoimmune Lymphoproliferative Syndrome/genetics, Biopsy, Caspase 8/genetics, Colitis, Ulcerative/genetics, Endoscopy, Gastrointestinal, Epithelial Cells/immunology, Genetic Predisposition to Disease, Heredity, Humans, Inflammasomes/immunology, Inflammation Mediators/immunology, Intestines/immunology, Lymphocytes/immunology, Mice, Knockout, Mutation, Phenotype, Artikel, Article
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10مورد إلكتروني
المصدر: ChemBioChem vol.19 (2018) date: 2018-12-04 nr.23 p.2490-2494 [ISSN 1439-4227]
مصطلحات الفهرس: caspases, cucurbit[8]uril, protein assembly, protein engineering, supramolecular chemistry, Enzyme Reactivators/chemistry, Catalysis/drug effects, Imidazoles/chemistry, Protein Multimerization/drug effects, Humans, Bridged-Ring Compounds/chemistry, Point Mutation, Caspase 8/genetics, Tijdschriftartikel, Article
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