المؤلفون: Broce, Iris J, Sirkis, Daniel W, Nillo, Ryan M, Bonham, Luke W, Lee, Suzee E, Miller, Bruce L, Castruita, Patricia A, Sturm, Virginia E, Sugrue, Leo S, Desikan, Rahul S, Yokoyama, Jennifer S

مصطلحات موضوعية: Biomedical and Clinical Sciences, Neurosciences, Rare Diseases, ALS, Stem Cell Research, Dementia, Frontotemporal Dementia (FTD), Aging, Neurodegenerative, Genetics, Brain Disorders, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Acquired Cognitive Impairment, Alzheimer's Disease Related Dementias (ADRD), 2.1 Biological and endogenous factors, Underpinning research, 1.1 Normal biological development and functioning, Aetiology, Neurological, C9orf72, amyotrophic lateral sclerosis, frontotemporal dementia, imaging transcriptomics, gene networks, neurodegeneration, Psychology, Cognitive Sciences, Biological psychology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2dx5985q
https://escholarship.org/content/qt2dx5985q/qt2dx5985q.pdf

المؤلفون: Castruita, Patricia, Piña-Escudero, Stefanie, Rentería, Miguel, Yokoyama, Jennifer

المصدر: Current Genetic Medicine Reports. 10(3)

مصطلحات موضوعية: Environment, Frailty, Genetics, Healthy aging, Resilience

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/90n7b069

المؤلفون: Maor-Nof, Maya, Shipony, Zohar, Lopez-Gonzalez, Rodrigo, Nakayama, Lisa, Zhang, Yong-Jie, Couthouis, Julien, Blum, Jacob A, Castruita, Patricia A, Linares, Gabriel R, Ruan, Kai, Ramaswami, Gokul, Simon, David J, Nof, Aviv, Santana, Manuel, Han, Kyuho, Sinnott-Armstrong, Nasa, Bassik, Michael C, Geschwind, Daniel H, Tessier-Lavigne, Marc, Attardi, Laura D, Lloyd, Thomas E, Ichida, Justin K, Gao, Fen-Biao, Greenleaf, William J, Yokoyama, Jennifer S, Petrucelli, Leonard, Gitler, Aaron D

المصدر: Cell. 184(3)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Stem Cell Research, Brain Disorders, ALS, Genetics, Frontotemporal Dementia (FTD), Neurodegenerative, Acquired Cognitive Impairment, Rare Diseases, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Stem Cell Research - Induced Pluripotent Stem Cell - Human, Dementia, Stem Cell Research - Induced Pluripotent Stem Cell, Neurosciences, 1.1 Normal biological development and functioning, Underpinning research, Aetiology, 2.1 Biological and endogenous factors, Neurological, Animals, Apoptosis Regulatory Proteins, Axons, C9orf72 Protein, Cell Death, Cells, Cultured, Cerebral Cortex, Chromatin, DNA Damage, DNA Repeat Expansion, Disease Models, Animal, Drosophila, Mice, Inbred C57BL, Nerve Degeneration, Protein Stability, Transcription, Genetic, Tumor Suppressor Protein p53, Tumor Suppressor Proteins, Mice, ATAC-seq, C9orf72, TDP-43, amyotrophic lateral sclerosis, axonal degeneration, neurodegeneration, p53, puma, Medical and Health Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6cm8z9gp

المؤلفون: Broce, Iris J, Castruita, Patricia A, Yokoyama, Jennifer S

مصطلحات موضوعية: Biological Psychology, Biomedical and Clinical Sciences, Neurosciences, Psychology, Dementia, Acquired Cognitive Impairment, Rare Diseases, Frontotemporal Dementia (FTD), Neurodegenerative, Orphan Drug, Brain Disorders, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Alzheimer's Disease Related Dementias (ADRD), Genetics, ALS, 2.1 Biological and endogenous factors, Aetiology, Neurological, Good Health and Well Being, clinical trials, genomics, precision medicine, amyotrophic lateral sclerosis, frontotemporal dementia, Cognitive Sciences, Biological psychology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/8kj2b07d

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المؤلفون: Alegro, Maryana, Theofilas, Panagiotis, Nguy, Austin, Castruita, Patricia A, Seeley, William, Heinsen, Helmut, Ushizima, Daniela M, Grinberg, Lea T

مصطلحات موضوعية: Biomedical and Clinical Sciences, Neurosciences, Bioengineering, Alzheimer Disease, Brain, Cell Count, Fluorescent Antibody Technique, Humans, Image Processing, Computer-Assisted, Machine Learning, Microscopy, Fluorescence, Pattern Recognition, Automated, Reproducibility of Results, Dictionary learning, Sparse models, Image segmentation, Immunofluorescence, Postmortem human brain, Microscopy, Psychology, Cognitive Sciences, Neurology & Neurosurgery

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/8sx4j02b
https://escholarship.org/content/qt8sx4j02b/qt8sx4j02b.pdf

المؤلفون: Broce, Iris J., Sirkis, Daniel W., Nillo, Ryan M., Bonham, Luke W., Lee, Suzee E., Miller, Bruce L., Castruita, Patricia A., Sturm, Virginia E., Sugrue, Leo S., Desikan, Rahul S., Yokoyama, Jennifer S.

المصدر: Frontiers in Neuroscience; 2024, p1-15, 15p

مصطلحات موضوعية: BRAIN cortical thickness, GENE regulatory networks, MEDIUM spiny neurons, DNA repair, GENE expression, COAT proteins (Viruses), AUTOPHAGY, GENE ontology

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المؤلفون: Alegro M; Memory and Aging Center, University of California San Francisco, 675 Nelson Rising Lane, San Francisco, CA 94158, USA. Electronic address: maryana.alegro@ucsf.edu., Theofilas P; Memory and Aging Center, University of California San Francisco, 675 Nelson Rising Lane, San Francisco, CA 94158, USA. Electronic address: panos.theofilas@ucsf.edu., Nguy A; Memory and Aging Center, University of California San Francisco, 675 Nelson Rising Lane, San Francisco, CA 94158, USA. Electronic address: austin.nguy@ucsf.edu., Castruita PA; Memory and Aging Center, University of California San Francisco, 675 Nelson Rising Lane, San Francisco, CA 94158, USA. Electronic address: alejandra.castcap@gmail.com., Seeley W; Memory and Aging Center, University of California San Francisco, 675 Nelson Rising Lane, San Francisco, CA 94158, USA. Electronic address: bill.seeley@ucsf.edu., Heinsen H; Medical School of the University of São Paulo, Av. Reboucas 381, São Paulo, SP 05401-000, Brazil. Electronic address: heinsen@mail.uni-wuerzburg.de., Ushizima DM; Computational Research Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Rd, Berkeley, CA 94720, USA; Berkeley Institute for Data Science, University of California Berkeley, Berkeley, CA 94720, USA. Electronic address: dushizima@lbl.gov., Grinberg LT; Memory and Aging Center, University of California San Francisco, 675 Nelson Rising Lane, San Francisco, CA 94158, USA. Electronic address: lea.grinberg@ucsf.edu.

المصدر: Journal of neuroscience methods [J Neurosci Methods] 2017 Apr 15; Vol. 282, pp. 20-33. Date of Electronic Publication: 2017 Mar 04.

نوع المنشور: Evaluation Study; Journal Article

بيانات الدورية: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7905558 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-678X (Electronic) Linking ISSN: 01650270 NLM ISO Abbreviation: J Neurosci Methods Subsets: MEDLINE

مواضيع طبية MeSH: Machine Learning*, Brain/*cytology , Image Processing, Computer-Assisted/*methods , Microscopy, Fluorescence/*methods , Pattern Recognition, Automated/*methods, Alzheimer Disease/pathology ; Cell Count/methods ; Fluorescent Antibody Technique/methods ; Humans ; Reproducibility of Results