المؤلفون: Campion, SN., Potter, DM., Bowman, CJ., Catlin, NR., Davis, S., Millard, C., Nowland, WS., Stethem, CM., Hollingshead, BD., Radi, ZA., Coder, PS., Cappon, GD.

المصدر: In Reproductive Toxicology October 2022 113:35-41

المؤلفون: Allerton CMN; Pfizer Research & Development, Cambridge, Massachusetts 02139, United States., Arcari JT; Pfizer Research & Development, Groton, Connecticut 06340, United States., Aschenbrenner LM; Pfizer Research & Development, Groton, Connecticut 06340, United States., Avery M; Pfizer Research & Development, Groton, Connecticut 06340, United States., Bechle BM; Pfizer Research & Development, Groton, Connecticut 06340, United States., Behzadi MA; Pfizer Research & Development, Pearl River, New York 10965, United States., Boras B; Pfizer Research & Development, La Jolla, California 92121, United States., Buzon LM; Pfizer Research & Development, Groton, Connecticut 06340, United States., Cardin RD; Pfizer Research & Development, Pearl River, New York 10965, United States., Catlin NR; Pfizer Research & Development, Groton, Connecticut 06340, United States., Carlo AA; Pfizer Research & Development, Groton, Connecticut 06340, United States., Coffman KJ; Pfizer Research & Development, Groton, Connecticut 06340, United States., Dantonio A; Pfizer Research & Development, Groton, Connecticut 06340, United States., Di L; Pfizer Research & Development, Groton, Connecticut 06340, United States., Eng H; Pfizer Research & Development, Groton, Connecticut 06340, United States., Farley KA; Pfizer Research & Development, Groton, Connecticut 06340, United States., Ferre RA; Pfizer Research & Development, La Jolla, California 92121, United States., Gernhardt SS; Pfizer Research & Development, Groton, Connecticut 06340, United States., Gibson SA; Institute for Antiviral Research, Department of Animal, Dairy, and Veterinary Sciences, Utah State University, Logan, Utah 84322, United States., Greasley SE; Pfizer Research & Development, La Jolla, California 92121, United States., Greenfield SR; Pfizer Research & Development, Cambridge, Massachusetts 02139, United States., Hurst BL; Institute for Antiviral Research, Department of Animal, Dairy, and Veterinary Sciences, Utah State University, Logan, Utah 84322, United States., Kalgutkar AS; Pfizer Research & Development, Cambridge, Massachusetts 02139, United States., Kimoto E; Pfizer Research & Development, Groton, Connecticut 06340, United States., Lanyon LF; Pfizer Research & Development, Groton, Connecticut 06340, United States., Lovett GH; Pfizer Research & Development, Cambridge, Massachusetts 02139, United States., Lian Y; Pfizer Research & Development, Groton, Connecticut 06340, United States., Liu W; Pfizer Research & Development, La Jolla, California 92121, United States., Martínez Alsina LA; Pfizer Research & Development, Groton, Connecticut 06340, United States., Noell S; Pfizer Research & Development, Groton, Connecticut 06340, United States., Obach RS; Pfizer Research & Development, Groton, Connecticut 06340, United States., Owen DR; Pfizer Research & Development, Cambridge, Massachusetts 02139, United States., Patel NC; Pfizer Research & Development, Cambridge, Massachusetts 02139, United States., Rai DK; Pfizer Research & Development, Groton, Connecticut 06340, United States., Reese MR; Pfizer Research & Development, Groton, Connecticut 06340, United States., Rothan HA; Pfizer Research & Development, Pearl River, New York 10965, United States., Sakata S; Pfizer Research & Development, La Jolla, California 92121, United States., Sammons MF; Pfizer Research & Development, Cambridge, Massachusetts 02139, United States., Sathish JG; Pfizer Research & Development, Pearl River, New York 10965, United States., Sharma R; Pfizer Research & Development, Groton, Connecticut 06340, United States., Steppan CM; Pfizer Research & Development, Groton, Connecticut 06340, United States., Tuttle JB; Pfizer Research & Development, Cambridge, Massachusetts 02139, United States., Verhoest PR; Pfizer Research & Development, Cambridge, Massachusetts 02139, United States., Wei L; Pfizer Research & Development, Groton, Connecticut 06340, United States., Yang Q; Pfizer Research & Development, Cambridge, Massachusetts 02139, United States., Yurgelonis I; Pfizer Research & Development, Pearl River, New York 10965, United States., Zhu Y; Pfizer Research & Development, Pearl River, New York 10965, United States.

المصدر: Journal of medicinal chemistry [J Med Chem] 2024 Aug 22; Vol. 67 (16), pp. 13550-13571. Date of Electronic Publication: 2024 Apr 30.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19 Drug Treatment* , SARS-CoV-2*/drug effects , Antiviral Agents*/pharmacology , Antiviral Agents*/pharmacokinetics , Antiviral Agents*/therapeutic use , Antiviral Agents*/chemistry , Protease Inhibitors*/pharmacology , Protease Inhibitors*/pharmacokinetics , Protease Inhibitors*/therapeutic use , Protease Inhibitors*/chemistry, Humans ; Animals ; Mice ; Administration, Oral ; Coronavirus 3C Proteases/antagonists & inhibitors ; Coronavirus 3C Proteases/metabolism ; Rats ; COVID-19/virology

المؤلفون: Catlin NR; Drug Safety Research and Development, Pfizer Research & Development, Groton, CT, USA. Electronic address: natasha.catlin@pfizer.com., Cappon GD; Drug Safety Research and Development, Pfizer Research & Development, Groton, CT, USA; Current: ToxStrategies, Katy, TX, USA., Davenport SD; Drug Safety Research and Development, Pfizer Research & Development, Groton, CT, USA., Stethem CM; Drug Safety Research and Development, Pfizer Research & Development, Groton, CT, USA., Nowland WS; Drug Safety Research and Development, Pfizer Research & Development, Groton, CT, USA., Campion SN; Drug Safety Research and Development, Pfizer Research & Development, Groton, CT, USA., Bowman CJ; Drug Safety Research and Development, Pfizer Research & Development, Groton, CT, USA.

المصدر: Reproductive toxicology (Elmsford, N.Y.) [Reprod Toxicol] 2024 Aug 09; Vol. 129, pp. 108686. Date of Electronic Publication: 2024 Aug 09.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Pergamon In Cooperation With The Reproductive Toxicology Center Country of Publication: United States NLM ID: 8803591 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-1708 (Electronic) Linking ISSN: 08906238 NLM ISO Abbreviation: Reprod Toxicol Subsets: MEDLINE

المؤلفون: Federspiel JD; Drug Safety Research & Development, Pfizer, Inc, Andover, Massachusetts, USA., Catlin NR; Drug Safety Research & Development, Pfizer, Inc, Groton, Connecticut, USA., Nowland WS; Drug Safety Research & Development, Pfizer, Inc, Groton, Connecticut, USA., Stethem CM; Drug Safety Research & Development, Pfizer, Inc, Groton, Connecticut, USA., Mathialagan N; Drug Safety Research & Development, Pfizer, Inc, Groton, Connecticut, USA., Fernandez Ocaña M; Drug Safety Research & Development, Pfizer, Inc, Andover, Massachusetts, USA., Bowman CJ; Drug Safety Research & Development, Pfizer, Inc, Groton, Connecticut, USA. Electronic address: christopher.j.bowman@pfizer.com.

المصدر: Molecular & cellular proteomics : MCP [Mol Cell Proteomics] 2024 Jul; Vol. 23 (7), pp. 100797. Date of Electronic Publication: 2024 Jun 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 101125647 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-9484 (Electronic) Linking ISSN: 15359476 NLM ISO Abbreviation: Mol Cell Proteomics Subsets: MEDLINE

مواضيع طبية MeSH: Proteomics*/methods , Ubiquitin-Protein Ligases*/metabolism , Thalidomide*/analogs & derivatives , Thalidomide*/pharmacology , Proteolysis*/drug effects, Animals ; Rabbits ; Female ; Embryo, Mammalian/metabolism ; Embryo, Mammalian/drug effects ; Adaptor Proteins, Signal Transducing/metabolism ; Lenalidomide/pharmacology ; Pregnancy

المؤلفون: Bowman CJ; Pfizer Research & Development, Groton, Connecticut, USA., Campion SN; Pfizer Research & Development, Groton, Connecticut, USA., Catlin NR; Pfizer Research & Development, Groton, Connecticut, USA., Nowland WS; Pfizer Research & Development, Groton, Connecticut, USA., Stethem CM; Pfizer Research & Development, Groton, Connecticut, USA., Radi ZA; Pfizer Research & Development, Cambridge, Massachusetts, USA., Cappon GD; Pfizer Research & Development, Groton, Connecticut, USA.

المصدر: Birth defects research [Birth Defects Res] 2024 May; Vol. 116 (5), pp. e2345.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101701004 Publication Model: Print Cited Medium: Internet ISSN: 2472-1727 (Electronic) NLM ISO Abbreviation: Birth Defects Res Subsets: MEDLINE

مواضيع طبية MeSH: Fertility*/drug effects , Janus Kinase 1*/antagonists & inhibitors , Janus Kinase 1*/metabolism , Pyrimidines*/pharmacology , Sulfonamides*/pharmacology, Female ; Animals ; Pregnancy ; Rats ; Rats, Sprague-Dawley ; Embryo Implantation/drug effects ; Janus Kinase Inhibitors/pharmacology ; Pregnancy Rate

المؤلفون: Catlin NR; Drug Safety Research, Development, & Medical, Pfizer Worldwide Research & Development, Groton, Connecticut 06340, USA., Bowman CJ; Drug Safety Research, Development, & Medical, Pfizer Worldwide Research & Development, Groton, Connecticut 06340, USA., Campion SN; Drug Safety Research, Development, & Medical, Pfizer Worldwide Research & Development, Groton, Connecticut 06340, USA., Lewis EM; Charles River Laboratories, Inc., Safety Assessment, Horsham, Pennsylvania 19044, USA., Nowland WS; Drug Safety Research, Development, & Medical, Pfizer Worldwide Research & Development, Groton, Connecticut 06340, USA., Stethem C; Drug Safety Research, Development, & Medical, Pfizer Worldwide Research & Development, Groton, Connecticut 06340, USA., Cappon GD; Drug Safety Research, Development, & Medical, Pfizer Worldwide Research & Development, Groton, Connecticut 06340, USA.

المصدر: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2022 Sep 24; Vol. 189 (2), pp. 225-236.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print Cited Medium: Internet ISSN: 1096-0929 (Electronic) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Diacylglycerol O-Acyltransferase*/metabolism , Diacylglycerol O-Acyltransferase*/pharmacology , Reproduction*, Animals ; Female ; Fertility ; Pregnancy ; Rabbits ; Rats ; Rats, Sprague-Dawley ; Triglycerides

المؤلفون: Catlin NR; Pfizer Worldwide Research, Development & Medical, Groton, CT, 06340, USA. Electronic address: natasha.catlin@pfizer.com., Bowman CJ; Pfizer Worldwide Research, Development & Medical, Groton, CT, 06340, USA., Campion SN; Pfizer Worldwide Research, Development & Medical, Groton, CT, 06340, USA., Cheung JR; Pfizer Worldwide Research, Development & Medical, Groton, CT, 06340, USA., Nowland WS; Pfizer Worldwide Research, Development & Medical, Groton, CT, 06340, USA., Sathish JG; Pfizer Worldwide Research, Development & Medical, Pearl River, NY, 10965, USA., Stethem CM; Pfizer Worldwide Research, Development & Medical, Groton, CT, 06340, USA., Updyke L; Pfizer Worldwide Research, Development & Medical, Cambridge, MA, 02139, USA., Cappon GD; Pfizer Worldwide Research, Development & Medical, Groton, CT, 06340, USA.

المصدر: Reproductive toxicology (Elmsford, N.Y.) [Reprod Toxicol] 2022 Mar; Vol. 108, pp. 56-61. Date of Electronic Publication: 2022 Jan 31.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Pergamon In Cooperation With The Reproductive Toxicology Center Country of Publication: United States NLM ID: 8803591 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-1708 (Electronic) Linking ISSN: 08906238 NLM ISO Abbreviation: Reprod Toxicol Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19 Drug Treatment*, Antiviral Agents/*toxicity , Embryonic Development/*drug effects , Fertility/*drug effects , Lactams/*toxicity , Leucine/*toxicity , Nitriles/*toxicity , Proline/*toxicity , Ritonavir/*toxicity, Animals ; Drug Combinations ; Female ; Infertility/chemically induced ; Male ; Pregnancy ; Rabbits ; Rats ; Rats, Wistar

المؤلفون: Catlin NR; Drug Safety Research and Development, Pfizer Worldwide Research and Development, Groton, Connecticut, USA., Cappon GD; Drug Safety Research and Development, Pfizer Worldwide Research and Development, Groton, Connecticut, USA., Engel S; Drug Safety Research and Development, Pfizer Worldwide Research and Development, Groton, Connecticut, USA., Rohde C; Drug Safety Research and Development, Pfizer Worldwide Research and Development, Pearl River, New York, USA., Nowland WS; Drug Safety Research and Development, Pfizer Worldwide Research and Development, Groton, Connecticut, USA., Buitrago S; Vaccine Research and Development, Pfizer Worldwide Research and Development, Pearl River, New York, USA., Scully I; Vaccine Research and Development, Pfizer Worldwide Research and Development, Pearl River, New York, USA., Anderson AS; Vaccine Research and Development, Pfizer Worldwide Research and Development, Pearl River, New York, USA., Bowman CJ; Drug Safety Research and Development, Pfizer Worldwide Research and Development, Groton, Connecticut, USA.

المصدر: Birth defects research [Birth Defects Res] 2021 Nov 15; Vol. 113 (19), pp. 1343-1356. Date of Electronic Publication: 2021 Sep 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101701004 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2472-1727 (Electronic) NLM ISO Abbreviation: Birth Defects Res Subsets: MEDLINE

مواضيع طبية MeSH: Immunization* , Streptococcus agalactiae*, Animals ; Female ; Fertility ; Humans ; Polysaccharides ; Pregnancy ; Rabbits ; Rats ; Rats, Sprague-Dawley ; Vaccines, Conjugate/toxicity

المؤلفون: Bowman CJ; Drug Safety Research and Development, Pfizer Worldwide Research, Development & Medical, Groton, CT, USA. Electronic address: christopher.j.bowman@pfizer.com., Bouressam M; Charles River Laboratories France Safety Assessmsent SAS, Lyon, France., Campion SN; Drug Safety Research and Development, Pfizer Worldwide Research, Development & Medical, Groton, CT, USA., Cappon GD; Drug Safety Research and Development, Pfizer Worldwide Research, Development & Medical, Groton, CT, USA., Catlin NR; Drug Safety Research and Development, Pfizer Worldwide Research, Development & Medical, Groton, CT, USA., Cutler MW; Vaccine Research and Development, Pfizer Worldwide Research, Development & Medical, Pearl River, NY, USA., Diekmann J; Non-Clinical Safety, BioNTech SE, Mainz, Germany., Rohde CM; Drug Safety Research and Development, Pfizer Worldwide Research, Development & Medical, Pearl River, NY, USA., Sellers RS; Drug Safety Research and Development, Pfizer Worldwide Research, Development & Medical, Pearl River, NY, USA., Lindemann C; Non-Clinical Safety, BioNTech SE, Mainz, Germany.

المصدر: Reproductive toxicology (Elmsford, N.Y.) [Reprod Toxicol] 2021 Aug; Vol. 103, pp. 28-35. Date of Electronic Publication: 2021 May 28.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Pergamon In Cooperation With The Reproductive Toxicology Center Country of Publication: United States NLM ID: 8803591 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-1708 (Electronic) Linking ISSN: 08906238 NLM ISO Abbreviation: Reprod Toxicol Subsets: MEDLINE

مواضيع طبية MeSH: Fertility* , Fetal Development*, COVID-19 Vaccines/*toxicity, Animals ; Antibodies, Neutralizing/blood ; Antibodies, Viral/blood ; BNT162 Vaccine ; COVID-19 Vaccines/pharmacology ; Cesarean Section ; Female ; Lactation ; Pregnancy ; Rats ; Rats, Wistar

المؤلفون: Catlin NR; Drug Safety Research and Development, Pfizer Worldwide Research & Development, Groton, CT., Bowman CJ; Drug Safety Research and Development, Pfizer Worldwide Research & Development, Groton, CT., Campion SN; Drug Safety Research and Development, Pfizer Worldwide Research & Development, Groton, CT., Davenport SD; Drug Safety Research and Development, Pfizer Worldwide Research & Development, Groton, CT., Esler WP; Internal Medicine Research Unit, Pfizer Worldwide Research & Development, Cambridge, MA., Kumpf SW; Drug Safety Research and Development, Pfizer Worldwide Research & Development, Groton, CT., Lewis EM; Charles River Laboratories, Inc, Safety Assessment, Horsham, PA., Nowland WS; Drug Safety Research and Development, Pfizer Worldwide Research & Development, Groton, CT., Ross TT; Internal Medicine Research Unit, Pfizer Worldwide Research & Development, Cambridge, MA., Stedman DS; Drug Safety Research and Development, Pfizer Worldwide Research & Development, Groton, CT., Stethem C; Drug Safety Research and Development, Pfizer Worldwide Research & Development, Groton, CT., Cappon GD; Drug Safety Research and Development, Pfizer Worldwide Research & Development, Groton, CT.

المصدر: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2021 Jan 28; Vol. 179 (2), pp. 183-194.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print Cited Medium: Internet ISSN: 1096-0929 (Electronic) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Acetyl-CoA Carboxylase*/genetics , Acetyl-CoA Carboxylase*/metabolism , Diabetes Mellitus, Type 2*, Animals ; Lipogenesis ; Mice ; Rabbits ; Rats ; Rats, Sprague-Dawley ; Zebrafish/metabolism