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1
المؤلفون: Yue-Ting Wang, Estelle M Maes, Lance Heinle, Kenneth Ruterbories, Stella Doktor, Mary Larsen, Amanda Olson, Andrew Lee, Cecilia Van Handel, Qin C Ji, Kelly Desino, Gary J Jenkins
المصدر: Bioanalysis. 15:161-176
مصطلحات موضوعية: Medical Laboratory Technology, Clinical Biochemistry, General Medicine, General Pharmacology, Toxicology and Pharmaceutics, Analytical Chemistry
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2
المؤلفون: Eric A. Voight, John T. Randolph, Daniel A.J. Bow, James N Newton, Brice E Uno, Greszler Stephen N, David A. Degoey, DeAnne Stolarik, Kenneth M Gleason, Cecilia Van Handel
المصدر: Journal of medicinal chemistry. 63(19)
مصطلحات موضوعية: Drug, Benzimidazole, Pyrrolidines, media_common.quotation_subject, Prodrug, Viral Nonstructural Proteins, Combinatorial chemistry, Antiviral Agents, Dosage form, Pibrentasvir, chemistry.chemical_compound, Mice, Dogs, chemistry, Solubility, In vivo, Area Under Curve, Drug Discovery, Molecular Medicine, Moiety, Animals, Benzimidazoles, Prodrugs, media_common
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3
المؤلفون: Preethi Krishnan, Rodger F. Henry, Christopher C. Marvin, Tatyana Dekhtyar, Rolf Wagner, John T. Randolph, A. Chris Krueger, David A. Degoey, Vincent Peterkin, Michelle Irvin, Geoff T. Halvorsen, Jason P. Shanley, Heyman Howard R, Eric A. Voight, Robert A. Carr, Cecilia Van Handel, Tongmei Li, Brian S. Brown, Daniel A.J. Bow, Hui-Ju Chen, DeAnne Stolarik
المصدر: Bioorganicmedicinal chemistry. 28(1)
مصطلحات موضوعية: Sofosbuvir, Hepatitis C virus, Clinical Biochemistry, Pharmaceutical Science, Hepacivirus, Microbial Sensitivity Tests, Pharmacology, medicine.disease_cause, Virus Replication, 01 natural sciences, Biochemistry, Antiviral Agents, chemistry.chemical_compound, Structure-Activity Relationship, In vivo, Drug Discovery, medicine, Humans, Prodrugs, Molecular Biology, NS5B, Uridine, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Organic Chemistry, Phosphoramidate, Hepatitis C, Prodrug, medicine.disease, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Hepatocytes, Molecular Medicine, Nucleoside, medicine.drug
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4
المؤلفون: John T. Randolph, Vincent Peterkin, Robert A. Carr, David A. Degoey, Tongmei Li, Daniel A.J. Bow, Hui-Ju Chen, Preethi Krishnan, DeAnne Stolarik, Rolf Wagner, Cecilia Van Handel, Michelle Irvin, A. Chris Krueger, Heyman Howard R, Tatyana Dekhtyar
المصدر: Bioorganic & Medicinal Chemistry Letters. 30:126986
مصطلحات موضوعية: Aminoisobutyric Acids, Clinical Biochemistry, Pharmaceutical Science, Hepacivirus, Microbial Sensitivity Tests, Viral Nonstructural Proteins, Pharmacology, Virus Replication, Antiviral Agents, 01 natural sciences, Biochemistry, chemistry.chemical_compound, Dogs, Organophosphorus Compounds, Drug Discovery, medicine, Animals, Humans, Prodrugs, Enzyme Inhibitors, Molecular Biology, Polymerase, biology, medicine.diagnostic_test, 010405 organic chemistry, Chemistry, Organic Chemistry, Phosphoramidate, Metabolism, Prodrug, RNA-Dependent RNA Polymerase, Deoxyuridine, Uridine, In vitro, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Liver, Liver biopsy, Hepatocytes, biology.protein, Molecular Medicine, Nucleoside