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1دورية أكاديمية
المؤلفون: Fu, Dong-Jun, Zhang, Li, Song, Jian, Mao, Ruo-Wang, Zhao, Ruo-Han, Liu, Ying-Chao, Hou, Yu-Hui, Li, Jia-Huan, Yang, Jia-Jia, Jin, Cheng-Yun, Li, Ping, Zi, Xiao-Lin, Liu, Hong-Min, Zhang, Sai-Yang, Zhang, Yan-Bing
المصدر: European journal of medicinal chemistry. 127
مصطلحات موضوعية: Antineoplastic Agents: chemical synthesis, chemistry, pharmacology, Apoptosis: drug effects, Cell Line, Tumor, Cell Movement: drug effects, Cell Proliferation: drug effects, Chemistry Techniques, Synthetic, Dose-Response Relationship, Drug, Drug Design, Drug Screening Assays, Antitumor, Drug Synergism, G1 Phase Cell Cycle Checkpoints: drug effects, Humans, Isoflavones: chemical synthesis, chemistry, pharmacology, MAP Kinase Signaling System: drug effects, Structure-Activity Relationship, Thiocarbamates: chemistry, Wnt Signaling Pathway: drug effects
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/2jw7m037
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المؤلفون: Marina Ivanišević, Heidi Miedl, Ursula Weiss-Fuchs, Désirée Forstner, Gernot Desoye, Djelmis J, Julia Bandres-Meriz, Ursula Hiden, Denise Hoch, Alejandro Majali-Martinez, Martin Gauster
المصدر: International Journal of Molecular Sciences, Vol 22, Iss 10989, p 10989 (2021)
International Journal of Molecular Sciencesمصطلحات موضوعية: endocrine system diseases, Placenta, Cell Cycle Proteins, Cell Movement, Pregnancy, Trophoblasts / cytology, Mannitol, glucose, Biology (General), Spectroscopy, Placenta / metabolism, early pregnancy, diabetes, Communication, human trophoblasts, General Medicine, Cell cycle, Cell Movement / drug effects, Trophoblasts, Computer Science Applications, Chemistry, medicine.anatomical_structure, embryonic structures, Gestation, Female, Adult, QH301-705.5, Ki-67 Antigen / genetics, Down-Regulation, Cell Cycle Proteins / metabolism, Trophoblasts / drug effects, Biology, Down-Regulation / drug effects, Catalysis, Inorganic Chemistry, Andrology, Downregulation and upregulation, Diabetes Mellitus, Type 1 / pathology, In vivo, Diabetes mellitus, Mannitol / pharmacology, medicine, Humans, Physical and Theoretical Chemistry, Ki-67 Antigen / metabolism, QD1-999, Molecular Biology, Cell Proliferation, Type 1 diabetes, Organic Chemistry, Placentation / drug effects, nutritional and metabolic diseases, Trophoblast, Cell Cycle Checkpoints, medicine.disease, Placentation, Trophoblasts / metabolism, Glucose / pharmacology, Pregnancy Trimester, First, Diabetes Mellitus, Type 1, Ki-67 Antigen, Cell Proliferation / drug effects, Cell Cycle Checkpoints / drug effects
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1b45fcbea321d46b42ca47bb60f0114
https://doi.org/10.3390/ijms222010989 -
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المؤلفون: Patrícia M. A. Silva, Ana C. Henriques, Bruno Sarmento, Hassan Bousbaa
المساهمون: Instituto de Investigação e Inovação em Saúde
المصدر: Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)مصطلحات موضوعية: Molecular biology, Antineoplastic Agents / pharmacology, Apoptosis, Cell Cycle Proteins, chemistry.chemical_compound, Cancer, Mad2 Proteins / metabolism, Sulfonamides, Multidisciplinary, Navitoclax, Aniline Compounds, Cell Death, Nuclear Proteins / metabolism, Paclitaxel / pharmacology, Nuclear Proteins, siRNAs, Spindle checkpoint, Oncology, Cell Death / drug effects, Mad2 Proteins, Medicine, Spindle Apparatus / drug effects, Programmed cell death, Cell biology, Paclitaxel, Science, Mitosis, Cell Cycle Proteins / metabolism, Antineoplastic Agents, Spindle Apparatus, Apoptosis / drug effects, Article, Target validation, Aniline Compounds / pharmacology, Cell Line, Tumor, Mitosis / drug effects, Gene silencing, Humans, Sulfonamides / pharmacology, Adaptor Proteins, Signal Transducing, Cell Cycle Checkpoints, chemistry, Mitotic exit, A549 Cells, Spindle Apparatus / metabolism, Cancer cell, Cancer research, Adaptor Proteins, Signal Transducing / drug effects, Cell Cycle Checkpoints / drug effects
وصف الملف: application/pdf
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المؤلفون: Sophie Reffet, Stéphane Dalle, Lucien Marchand, Charles Thivolet, Nicole Fabien, Emmanuel Disse, Julien Vouillarmet, Christine Cugnet-Anceau
المساهمون: Centre hospitalier Saint-Joseph Saint-Luc, Cardiovasculaire, métabolisme, diabétologie et nutrition (CarMeN), Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Institut National de la Recherche Agronomique (INRA), Centre Hospitalier Lyon Sud [CHU - HCL] (CHLS), Hospices Civils de Lyon (HCL), Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hospices Civils de Lyon (HCL), Institut de biologie et chimie des protéines [Lyon] (IBCP), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)
المصدر: Acta diabetologica
Acta diabetologica, 2019, 56 (12), pp.1239--1245. ⟨10.1007/s00592-019-01402-w⟩مصطلحات موضوعية: Endocrinology, Diabetes and Metabolism, Fulminant, medicine.medical_treatment, [SDV]Life Sciences [q-bio], Type 2 diabetes, 030204 cardiovascular system & hematology, Bioinformatics, Anti-PD-L1, B7-H1 Antigen, Autoimmune diabetes, Alpha cell pancreatic function, 0302 clinical medicine, Endocrinology, Fulminant diabetes, CTLA-4 Antigen, Lipoatrophy, Autoimmune lipodystrophy, Autoimmune pancreatitis, Diabetes Mellitus, Lipoatrophic, Autoimmune generalised lipoatrophy, Type 1/chemically induced/complications/diagnosis/epidemiology, General Medicine, Anti-PD-1, 3. Good health, Programmed death ligand 1 (PD-L1), Immunotherapy, Autoimmune Diseases/chemically induced/epidemiology/etiology, 030209 endocrinology & metabolism, Context (language use), Type 2/*chemically induced/diagnosis/epidemiology/immunology, Autoimmune Diseases, 03 medical and health sciences, Diabetes mellitus, Internal Medicine, medicine, Diabetes Mellitus, Protein Kinase Inhibitors/*adverse effects/therapeutic use, Humans, Decompensation, Immunotherapy/*adverse effects, Protein Kinase Inhibitors, CTLA-4 Antigen/antagonists & inhibitors/immunology, Immune checkpoint inhibitors side effects, business.industry, Programmed cell death-1 (PD-1), Pancreas volume, Cell Cycle Checkpoints, medicine.disease, Cell Cycle Checkpoints/drug effects/immunology, Lipoatrophic/chemically induced/epidemiology/immunology, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Exocrine pancreatic function, Beta cell pancreatic function, business, B7-H1 Antigen/antagonists & inhibitors/immunology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30cf7580fcdfdce130547728c6f643f8
https://pubmed.ncbi.nlm.nih.gov/31423559 -
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المؤلفون: Fabio Gomes, Fiona H Blackhall, Kristopher K. Frese, Katie Baker, Martin Forster, Maximilian W Schenk, Alice Lallo, Victoria Foy, Caroline Dive
المصدر: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
Foy, V, Schenk, M, Baker, K, Gomes, F, Lallo, A, Frese, K, Forster, M, Dive, C & Blackhall, F 2017, ' Targeting DNA damage in SCLC ', Lung Cancer, vol. 114, 11, pp. 12-22 . https://doi.org/10.1016/j.lungcan.2017.10.006مصطلحات موضوعية: 0301 basic medicine, Genome instability, Cancer Research, Cell cycle checkpoint, Lung Neoplasms, DNA Repair, Protein Kinase Inhibitors/therapeutic use, Piperazines, Cell Proliferation/drug effects, Small Cell Lung Carcinoma/genetics, 0302 clinical medicine, Phthalazines/therapeutic use, Aurora Kinases, Molecular Targeted Therapy, Etoposide, Genetics, Rad51 Recombinase/antagonists & inhibitors, Manchester Cancer Research Centre, Cytotoxins, Azepines, Oncology, Cell Cycle Checkpoints/genetics, Heterocyclic Compounds, 4 or More Rings/therapeutic use, Rad51 Recombinase/therapeutic use, 030220 oncology & carcinogenesis, medicine.drug, Pulmonary and Respiratory Medicine, Benzimidazoles/therapeutic use, Lung Neoplasms/genetics, DNA damage, DNA repair, Context (language use), Poly(ADP-ribose) Polymerase Inhibitors, Heterocyclic Compounds, 4 or More Rings, Genomic Instability, 03 medical and health sciences, Cell Proliferation/genetics, medicine, Cytotoxins/therapeutic use, Humans, CHLC ONC, Lung cancer, Lung Neoplasms/drug therapy, Protein Kinase Inhibitors, Cell Proliferation, business.industry, ResearchInstitutes_Networks_Beacons/mcrc, Pyrimidines/therapeutic use, Small Cell Lung Carcinoma/drug therapy, Cell Cycle Checkpoints, Carbolines/therapeutic use, Cell Cycle Checkpoints/drug effects, Etoposide/therapeutic use, medicine.disease, Small Cell Lung Carcinoma, Piperazines/therapeutic use, respiratory tract diseases, 030104 developmental biology, Pyrimidines, DNA Damage/drug effects, Genomic Instability/drug effects, Cancer cell, Cancer research, Phthalazines, Benzimidazoles, Azepines/therapeutic use, Rad51 Recombinase, DNA Damage/genetics, Poly(ADP-ribose) Polymerase Inhibitors/therapeutic use, business, Aurora Kinases/therapeutic use, Genomic Instability/genetics, Molecular Targeted Therapy/methods, Carbolines, DNA Damage
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2d985075e4d708fa0a6f83fb0013005
https://hdl.handle.net/10400.17/2823 -
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المؤلفون: Christoph Schwärzler, Sylvain Lemeille, Wolf-Henning Boehncke, Hedwig Sutterlüty-Fall, Marylise Fernandez, Rastine Merat
المصدر: Cancer Medicine, Vol. 6, No 7 (2017) pp. 1652-1664
Cancer Medicineمصطلحات موضوعية: 0301 basic medicine, Cancer Research, Indoles, medicine.medical_treatment, Gene Expression, ddc:616.07, Targeted therapy, ELAV-Like Protein 1, Cell Proliferation/drug effects, single-cell mass cytometry, Melanoma/drug therapy/genetics/metabolism, Mice, ELAV-Like Protein 1/genetics, Transduction, Genetic, Gene expression, Molecular Targeted Therapy, Vemurafenib, Cancer Biology, ddc:616, Sulfonamides, Tumor, Cell Death, Indoles/pharmacology, Melanoma, Adaptive response, targeted therapy, Genetic Vectors/genetics, Oncology, Cell Cycle Checkpoints/drug effects/genetics, medicine.drug, BRAF inhibitor, Proto-Oncogene Proteins B-raf, cell heterogeneity, Sulfonamides/pharmacology, RNA‐binding protein HuR, Genetic Vectors, Short Report, Biology, Adenoviridae, Cell Line, Proto-Oncogene Proteins B-raf/antagonists & inhibitors/genetics/metabolism, 03 medical and health sciences, Protein Kinase Inhibitors/pharmacology/therapeutic use, Transduction, Antigen, Genetic, single‐cell mass cytometry, Cell Line, Tumor, medicine, melanoma, Animals, Humans, Radiology, Nuclear Medicine and imaging, Mass cytometry, Cell Death/drug effects/genetics, Adenoviridae/genetics, Protein Kinase Inhibitors, Cell Proliferation, Animal, Cell subpopulations, Cell Cycle Checkpoints, medicine.disease, Xenograft Model Antitumor Assays, Disease Models, Animal, 030104 developmental biology, Immunology, Disease Models, Cancer research, RNA-binding protein HuR
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مصطلحات موضوعية: Apoptosis/drug effects, Carcinoma, Neuroendocrine/*drug therapy/metabolism, Cell Cycle Checkpoints/drug effects, Cell Line, Tumor, Cell Movement/*drug effects, Cell Proliferation/*drug effects, Cell Survival/drug effects, Coumaric Acids/*pharmacology, Gene Expression Regulation, Neoplastic/drug effects, Humans, Neoplasm Proteins/*metabolism, RNA, Messenger/metabolism, Signal Transduction/drug effects, Thyroid Neoplasms/*drug therapy/metabolism, Up-Regulation/drug effects
URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______3566::5fc6a307bb0e8ffa21d70907daa8d070
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مصطلحات موضوعية: Antineoplastic Agents/*pharmacology, Antioxidants/*pharmacology, Apoptosis/*drug effects, Cell Division/drug effects, Cell Line, Tumor, Cell Movement/drug effects, Cell Proliferation/drug effects, Cell Survival/drug effects, G1 Phase Cell Cycle Checkpoints/*drug effects, Gene Expression Regulation, Neoplastic/drug effects, Humans, In Situ Nick-End Labeling, Iridoids/*pharmacology, Neoplasm Invasiveness/pathology, Neuroblastoma/*drug therapy/*pathology, Wound Healing/drug effects
URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______3566::f04f03205859d520275cd6d5dba8f56c
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المؤلفون: Ons, Zakraoui, Cezary, Marcinkiewicz, Zohra, Aloui, Houcemeddine, Othman, Renaud, Grépin, Meriam, Haoues, Makram, Essafi, Najet, Srairi-Abid, Ammar, Gasmi, Habib, Karoui, Gilles, Pagès, Khadija, Essafi-Benkhadir
المساهمون: Laboratoire d'Epidémiologie Moléculaire et de Pathologie Expérimentale Appliquée aux Maladies Infectieuses (LR11IPT04), Université de Tunis El Manar (UTM)-Institut Pasteur de Tunis, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Université de Tunis El Manar (UTM), Temple University [Philadelphia], Pennsylvania Commonwealth System of Higher Education (PCSHE), Laboratoire des Venins et Biomolécules Thérapeutiques - Laboratory of Venoms and Therapeutic Biomolecules (LR11IPT08), Institut Pasteur de Tunis, Centre Scientifique de Monaco (CSM), Laboratoire de Transmission, Contrôle et Immunobiologie des Infections - Laboratory of Transmission, Control and Immunobiology of Infection (LR11IPT02), Institut de Recherche sur le Cancer et le Vieillissement (IRCAN), Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA), This work was supported by the Tunisian Ministry of Higher Education and Scientific Research, the Institut Pasteur International Network (RIIP) and the University of Nice Sophia Antipolis, the French National Institute of Cancer (INCA) and the French Association for cancer research (ARC).
المصدر: Molecular Carcinogenesis
Molecular Carcinogenesis, Wiley, 2016, 56, pp.18-35. ⟨10.1002/mc.22470⟩مصطلحات موضوعية: Models, Molecular, Vascular Endothelial Growth Factor A, MESH: Vascular Endothelial Growth Factor A/genetics, MESH: Neovascularization, Pathologic/drug therapy, MESH: Colonic Neoplasms/drug therapy, MESH: Colonic Neoplasms/pathology, Apoptosis, MESH: MAP Kinase Signaling System/drug effects, MESH: Cell Proliferation/drug effects, Lebein, MESH: Colon/drug effects, MESH: Animals, MESH: Colon/metabolism, Neovascularization, Pathologic, MESH: Antineoplastic Agents/pharmacology, Integrin beta1, MESH: Chickens, MESH: Neovascularization, Pathologic/genetics, disintegrin, tumor growth, colon cancer, Colonic Neoplasms, MESH: Antineoplastic Agents/therapeutic use, MESH: Models, Molecular, MESH: Apoptosis/drug effects, MESH: Cell Line, Tumor, Colon, MAP Kinase Signaling System, MESH: Vascular Endothelial Growth Factor A/metabolism, Down-Regulation, Mice, Nude, Antineoplastic Agents, MESH: Viper Venoms/therapeutic use, [SDV.CAN]Life Sciences [q-bio]/Cancer, Viper Venoms, MESH: Cell Cycle Checkpoints/drug effects, MESH: Viper Venoms/pharmacology, Cell Line, Tumor, MESH: Down-Regulation/drug effects, MESH: Mice, Nude, Animals, Humans, MESH: Integrin beta1/metabolism, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Cell Proliferation, cellular effectors, MESH: Humans, Cell Cycle Checkpoints, MESH: Colonic Neoplasms/metabolism, MESH: Reactive Oxygen Species/metabolism, MESH: Colonic Neoplasms/genetics, MESH: Neovascularization, Pathologic/metabolism, MESH: Neovascularization, Pathologic/pathology, MESH: Colon/pathology, Reactive Oxygen Species, Chickens, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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المؤلفون: Hervé Sartelet, Anne-Laure Rougemont, Raouf Fetni, Monique Fabre, Stefan Michiels, Gilles Vassal, Mona Beaunoyer, Michel Duval, M. Castaing
المصدر: Human Pathology, Vol. 42, No 11 (2011) pp. 1727-39
مصطلحات موضوعية: Vascular Endothelial Growth Factor A, Morpholines, PTEN Phosphohydrolase/metabolism, Doxorubicin/pharmacology, ddc:616.07, Tropomyosin receptor kinase C, Receptor tyrosine kinase, Pathology and Forensic Medicine, Neuroblastoma, Thioredoxins, Proto-Oncogene Proteins c-akt/antagonists & inhibitors/metabolism, Growth factor receptor, Cell Line, Tumor, Thioredoxins/physiology, Humans, Everolimus, Epidermal growth factor receptor, Protein kinase B, PI3K/AKT/mTOR pathway, Sirolimus, biology, Akt/PKB signaling pathway, Vascular Endothelial Growth Factor A/metabolism, PTEN Phosphohydrolase, Infant, Cell Cycle Checkpoints/drug effects, Cell Cycle Checkpoints, Cell biology, Enzyme Activation, Sirolimus/analogs & derivatives/pharmacology, Chromones, Doxorubicin, biology.protein, Cancer research, Chromones/pharmacology, Morpholines/pharmacology, Phosphatidylinositol 3-Kinase, Thioredoxin, Neuroblastoma/physiopathology/secondary, Phosphatidylinositol 3-Kinase/metabolism, Proto-Oncogene Proteins c-akt
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