المؤلفون: Sarah Batson, Cesira de Chiara, Vita Majce, Adrian J. Lloyd, Stanislav Gobec, Dean Rea, Vilmos Fülöp, Christopher W. Thoroughgood, Katie J. Simmons, Christopher G. Dowson, Colin W. G. Fishwick, Luiz Pedro S. de Carvalho, David I. Roper

المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/66e59bce52674d29b83d6b33b62cc099

المؤلفون: João P. Pisco, Cesira de Chiara, Kamila J. Pacholarz, Acely Garza-Garcia, Roksana W. Ogrodowicz, Philip A. Walker, Perdita E. Barran, Stephen J. Smerdon, Luiz Pedro S. de Carvalho

المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/603702800eb7417086645e28e6a8150e

المؤلفون: Rajesh P. Menon, Daniel Soong, Cesira de Chiara, Mark Holt, John E. McCormick, Narayana Anilkumar, Annalisa Pastore

المصدر: PeerJ, Vol 2, p e323 (2014)

مصطلحات موضوعية: Foci, Misfolding diseases, FRET, Confocal microscopy, Spinocerebellar ataxia type 1, Medicine, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://peerj.com/articles/323.pdf; https://peerj.com/articles/323/; https://doaj.org/toc/2167-8359

URL الوصول: https://doaj.org/article/fe885deeb75747f499782483eef48fa5

المؤلفون: Cesira de Chiara, Rajesh P Menon, Geoff Kelly, Annalisa Pastore

المصدر: PLoS ONE, Vol 8, Iss 10, p e76456 (2013)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3796545?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/70b99a49e3d246ad94743878c840b809

المؤلفون: Cesira de Chiara, Rajesh P Menon, Molly Strom, Toby J Gibson, Annalisa Pastore

المصدر: PLoS ONE, Vol 4, Iss 12, p e8372 (2009)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC2791216?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/6ebdbab494c048fd930a008d42e4e261

المؤلفون: Cesira de Chiara, Gareth A. Prosser, Roksana Ogrodowicz, Luiz P. S. de Carvalho

المصدر: ACS Bio & Med Chem Au.

مصطلحات موضوعية: Drug Discovery, Pharmaceutical Science, Molecular Biology, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1c4268c64b56cac4038960a959c37010
https://doi.org/10.1021/acsbiomedchemau.2c00074

المؤلفون: Cesira de Chiara, Gareth A. Prosser, Geoff Kelly, Luiz Pedro S. de Carvalho, Acely Garza-Garcia, Miha Homšak, Edward W. Tate, Andrew Purkiss, Holly L. Douglas

المصدر: Nature chemical biology

مصطلحات موضوعية: Protein Conformation, D-cycloserine, Isomerase, Cofactor, Article, Mycobacterium tuberculosis, Ligases, 03 medical and health sciences, chemistry.chemical_compound, Bacterial Proteins, Alanine racemase, Oximes, Escherichia coli, Amino Acid Sequence, Molecular Biology, Pyridoxal, Antibiotics, Antitubercular, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, DNA ligase, Alanine, Binding Sites, biology, 030302 biochemistry & molecular biology, Alanine Racemase, Cell Biology, Isoxazoles, biology.organism_classification, Recombinant Proteins, 3. Good health, Enzyme, Biochemistry, chemistry, Cycloserine, biology.protein, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21487e657b1d8a0a7a29c11800f7d513
http://europepmc.org/articles/PMC7246083

المؤلفون: Peter D. Craggs, Robert A. Field, Martin Rejzek, Cesira de Chiara, Luiz Pedro S. de Carvalho, Robert J. Young, Argyrides Argyrou, Stephane Mouilleron

المصدر: Craggs, PD, Mouilleron, S, Rejzek, M, de, C C, Young, RJ, Field, RA, Argyrou, A & de, C LPS 2018, ' The Mechanism of Acetyl Transfer Catalyzed by Mycobacterium tuberculosis GlmU. ', Biochemistry . https://doi.org/10.1021/acs.biochem.8b00121

مصطلحات موضوعية: 0301 basic medicine, Conformational change, Stereochemistry, Coenzyme A, Magnesium Chloride, Biochemistry, Substrate Specificity, 03 medical and health sciences, chemistry.chemical_compound, Bacterial Proteins, Multienzyme Complexes, Glucosamine, Manchester Institute of Biotechnology, Transferase, Enzyme Inhibitors, Ternary complex, chemistry.chemical_classification, Uridine Diphosphate N-Acetylglucosamine, Molecular Structure, 030102 biochemistry & molecular biology, Mycobacterium tuberculosis, Hydrogen-Ion Concentration, ResearchInstitutes_Networks_Beacons/manchester_institute_of_biotechnology, 3. Good health, Kinetics, 030104 developmental biology, Enzyme, chemistry, Acetyltransferase, Biocatalysis, Peptidoglycan

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f70615fd15328b8dd6a7313ac3479d25
https://doi.org/10.1021/acs.biochem.8b00121

المؤلفون: Dean Rea, Christopher W. Thoroughgood, Luiz Pedro S. de Carvalho, S. Batson, Cesira de Chiara, Vita Majce, David I. Roper, Vilmos Fülöp, Colin W. G. Fishwick, Katie J. Simmons, Christopher G. Dowson, Stanislav Gobec, Adrian J. Lloyd

المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Science, D-cycloserine, General Physics and Astronomy, chemical and pharmacologic phenomena, General Biochemistry, Genetics and Molecular Biology, Bacterial cell structure, Article, 03 medical and health sciences, Alanine racemase, medicine, Escherichia coli, Peptide Synthases, Phosphorylation, lcsh:Science, Antibiotics, Antitubercular, chemistry.chemical_classification, DNA ligase, Multidisciplinary, 030102 biochemistry & molecular biology, Escherichia coli Proteins, Cycloserine, Alanine Racemase, hemic and immune systems, General Chemistry, 3. Good health, QR, carbohydrates (lipids), 030104 developmental biology, Enzyme, chemistry, Biochemistry, Mechanism of action, lcsh:Q, medicine.symptom, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb8c3d91c18a7a14bfd843d766186dd0
http://wrap.warwick.ac.uk/95976/1/WRAP-inhibition-D-Ala-D-Ala-ligase-phosphorylated-antibiotic-Roper-2017.pdf

المؤلفون: Annalisa Pastore, Cesira de Chiara

المساهمون: De Chiara, Cesira, Pastore, Annalisa

المصدر: Trends in Neurosciences

مصطلحات موضوعية: Protein Folding, Spinocerebellar Ataxia Type 1, Review, Protein aggregation, Bioinformatics, Heredodegenerative Disorder, Nervous System, misfolding diseases, Protein-protein interaction, Nuclear protein, Ataxin-1, Nuclear Protein, DNA Repeat Expansion, Medicine (all), General Neuroscience, Nuclear Proteins, Ataxins, Peptide, Spinocerebellar ataxia, Heredodegenerative Disorders, Nervous System, Protein folding, Human, congenital, hereditary, and neonatal diseases and abnormalities, Neuroscience(all), Ataxin 1, Nerve Tissue Proteins, protein–protein interactions, Computational biology, Biology, Protein Aggregation, Pathological, protein aggregation, Protein–protein interaction, Protein Aggregates, Pathological, medicine, Animals, Humans, Neuroscience (all), Animal, Protein Biochemistry, medicine.disease, Protein Aggregation, Misfolding disease, Drug Design, Nerve Tissue Protein, biology.protein, Protein Aggregate, Protein Multimerization, Peptides, polyglutamine, Polyglutamine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10e1b210b28ef15e8c9eb6846cdb9cb9
https://doi.org/10.1016/j.tins.2014.02.003