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1دورية أكاديمية
المؤلفون: Huanyu Z. Li, Ashley C. W. Pike, Irina Lotsaris, Gamma Chi, Jesper S. Hansen, Sarah C. Lee, Karin E. J. Rödström, Simon R. Bushell, David Speedman, Adam Evans, Dong Wang, Didi He, Leela Shrestha, Chady Nasrallah, Nicola A. Burgess-Brown, Robert J. Vandenberg, Timothy R. Dafforn, Elisabeth P. Carpenter, David B. Sauer
المصدر: Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2041-1723
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2دورية أكاديمية
المؤلفون: Mariam El Khatib, Que-Tien Tran, Chady Nasrallah, Julie Lopes, Jean-Michel Bolla, Michel Vivaudou, Jean-Marie Pagès, Jacques-Philippe Colletier
المصدر: PLoS ONE, Vol 12, Iss 3, p e0174213 (2017)
وصف الملف: electronic resource
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3دورية أكاديمية
المؤلفون: Wanling Song, Harsha Bajaj, Chady Nasrallah, Hualiang Jiang, Mathias Winterhalter, Jacques-Philippe Colletier, Yechun Xu
المصدر: PLoS Computational Biology, Vol 11, Iss 5, p e1004255 (2015)
مصطلحات موضوعية: Biology (General), QH301-705.5
وصف الملف: electronic resource
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المؤلفون: Huanyu Z. Li, Ashley C.W. Pike, Gamma Chi, Jesper S. Hansen, Sarah G. Lee, Karin E.J. Rödström, Simon R. Bushell, David Speedman, Adam Evans, Dong Wang, Didi He, Leela Shrestha, Chady Nasrallah, Nicola A. Burgess-Brown, Timothy R. Dafforn, Elisabeth P. Carpenter, David B. Sauer
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3dd0b3c1551d3725c4f410b48f6a6e46
https://doi.org/10.1101/2023.05.17.541173 -
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المؤلفون: François Hoh, Julie Kniazeff, Juan Lorenzo Catena, Cyril Goudet, Jean-Philippe Pin, Xavier Gómez-Santacana, Anaëlle Dumazer, Jean-Louis Banères, Ludovic Berto, Fanny Malhaire, Amadeu Llebaria, Robert B. Quast, Alice E. Berizzi, Giuseppe Cannone, Kutti R. Vinothkumar, Chia-Ying Huang, Chady Nasrallah, Guillaume Lebon, Julie Briot, Joan Font-Ingles, Karine Rottier
المساهمون: Institut de Génomique Fonctionnelle (IGF), Université de Montpellier (UM)-Université Montpellier 1 (UM1)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Montpellier 2 - Sciences et Techniques (UM2)-Centre National de la Recherche Scientifique (CNRS), MRC Laboratory of Molecular Biology [Cambridge, UK] (LMB), University of Cambridge [UK] (CAM)-Medical Research Council, Paul Scherrer Institute (PSI), Centre de Biochimie Structurale [Montpellier] (CBS), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut des Biomolécules Max Mousseron [Pôle Chimie Balard] (IBMM), Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Laboratory of Medicinal Chemistry, Institute for Advanced Chemistry of Catalonia (MCS (IQAC-CSIC)), Tata Institute for Fundamental Research (TIFR), Ministerio de Ciencia e Innovación (España), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Guerineau, Nathalie C., MRC, Lab Mol Biol, Cambridge, England, Partenaires INRAE, The Swiss Light Source (SLS) (SLS-PSI), Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Institut de Química Avançada de Catalunya (IQAC), Consejo Superior de Investigaciones Científicas [Spain] (CSIC), National Centre for Biological Sciences [TIFR] (NCBS)
المصدر: Cell Reports
Cell Reports, Elsevier Inc, 2021, 36 (9), pp.109648. ⟨10.1016/j.celrep.2021.109648⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cell Reports, 2021, 36 (9), pp.109648. ⟨10.1016/j.celrep.2021.109648⟩مصطلحات موضوعية: Models, Molecular, Allosteric modulators, [SDV]Life Sciences [q-bio], G-protein-coupled receptors, Signal transduction, Crystallography, X-Ray, photochromic ligands, Excitatory Amino Acid Agonists, Receptor, Cryo-EM, 0303 health sciences, Metabotropic glutamate receptor 5, Chemistry, Protein Stability, 030302 biochemistry & molecular biology, metabotropic glutamate receptor 5, Glutamate receptor, 3. Good health, [SDV.BBM.BP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biophysics, [SDV] Life Sciences [q-bio], allosteric modulators, Glutamate, signal transduction, Protein Binding, Agonist, animal structures, medicine.drug_class, Receptor, Metabotropic Glutamate 5, Allosteric regulation, glutamate, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Structure-Activity Relationship, medicine, [CHIM.CRIS]Chemical Sciences/Cristallography, Humans, Protein Interaction Domains and Motifs, [CHIM.CRIS] Chemical Sciences/Cristallography, [SDV.BC] Life Sciences [q-bio]/Cellular Biology, 030304 developmental biology, G protein-coupled receptor, X-ray crystallography, Cryoelectron Microscopy, Protein Subunits, HEK293 Cells, Metabotropic glutamate receptor, Photochromic ligands, Biophysics, cryo-EM, Excitatory Amino Acid Antagonists
وصف الملف: application/pdf
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المؤلفون: Karine Rottier, Chady Nasrallah, Vincent Compan, Romain Marcellin, Jean-Philippe Pin, Guillaume Lebon, Joan Font, Jean Louis Banères, Amadeu Llebaria
المساهمون: Institut de Génomique Fonctionnelle (IGF), Université de Montpellier (UM)-Université Montpellier 1 (UM1)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Montpellier 2 - Sciences et Techniques (UM2)-Centre National de la Recherche Scientifique (CNRS), Institut des Biomolécules Max Mousseron [Pôle Chimie Balard] (IBMM), Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Ministerio de Economía y Competitividad (España)
المصدر: Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2018, 8 (1), pp.4407. ⟨10.1038/s41598-018-22729-4⟩
Digital.CSIC. Repositorio Institucional del CSIC
instnameمصطلحات موضوعية: 0301 basic medicine, G protein, GTP-Binding Protein alpha Subunits, [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, lcsh:Medicine, Receptors, Metabotropic Glutamate, 03 medical and health sciences, 0302 clinical medicine, Heterotrimeric G protein, Receptors, Metabotropic Glutamate, lcsh:Science, G protein-coupled receptor, Multidisciplinary, biology, Chemistry, mGlu receptor, lcsh:R, Glutamate binding, 3. Good health, Cell biology, 030104 developmental biology, Metabotropic receptor, Gq alpha subunit, Schizophrenia, biology.protein, lcsh:Q, Signal transduction, 030217 neurology & neurosurgery
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المؤلفون: Agnese Baronina, Chady Nasrallah, George Hedger, Elisabeth P. Carpenter, Mariana Grieben, Jiye Shi, Qinrui Wang, Robin A. Corey, Prafulla Aryal, Ashley C. W. Pike, Mark S.P. Sansom
المصدر: Structure(London, England:1993)
مصطلحات موضوعية: Models, Molecular, endocrine system, TRPP Cation Channels, TRPML, Molecular Dynamics Simulation, TRPP, Article, Protein Structure, Secondary, phosphatidylinositol bisphosphate, lipids, 03 medical and health sciences, Transient receptor potential channel, Phosphatidylinositol Phosphates, Structural Biology, TRP channel, Sf9 Cells, Animals, Humans, Binding site, education, Molecular Biology, Ciliary membrane, Ion channel, 030304 developmental biology, 0303 health sciences, education.field_of_study, Binding Sites, Chemistry, Cryoelectron Microscopy, 030302 biochemistry & molecular biology, cholesterol, molecular dynamics, Transmembrane protein, 3. Good health, Polycystin 2, polycystin-2, Biophysics, lipids (amino acids, peptides, and proteins), Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c4897dab5028aa94cc5be15dcca5f89
https://doi.org/10.1016/j.str.2019.11.005 -
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المؤلفون: Mariam, El-Khatib, Chady, Nasrallah, Julie, Lopes, Que-Tien, Tran, Guillaume, Tetreau, Hind, Basbous, Daphna, Fenel, Benoit, Gallet, Mathilde, Lethier, Jean-Michel, Bolla, Jean-Marie, Pagès, Michel, Vivaudou, Martin, Weik, Mathias, Winterhalter, Jacques-Philippe, Colletier
المصدر: Proceedings of the National Academy of Sciences of the United States of America. 115(10)
مصطلحات موضوعية: PNAS Plus, Biofilms, bacteria, Porins, Providencia, Crystallography, X-Ray, Dimerization, Bacterial Outer Membrane Proteins
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::584fe982c4ec41b5636dc0d19a3aa9d6
https://pubmed.ncbi.nlm.nih.gov/29476011 -
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المؤلفون: Jean-Marie Pagès, Guillaume Tetreau, Julie Lopes, Michel Vivaudou, Que-Tien Tran, Mathilde Lethier, Mathias Winterhalter, Jean-Michel Bolla, Hind Basbous, Martin Weik, Chady Nasrallah, Mariam El-Khatib, Jacques-Philippe Colletier, Daphna Fenel, Benoit Gallet
المساهمون: Institut de biologie structurale (IBS - UMR 5075 ), Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Jacobs University [Bremen], Membranes et cibles thérapeutiques (MCT), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Recherche Biomédicale des Armées [Brétigny-sur-Orge] (IRBA), Institut de pharmacologie et de biologie structurale (IPBS), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS), We thank E. Kandiah, D. Cascio, M. R. Sawaya, I. Silman, and J. Zaccaï for critically reading the manuscript, C. Breyton and D. Levy for suggesting on-column delipidation of porins and sucrose gradient experiments, respectively, and A. Martel, A. Le Roy, A. Flayhan, A. Laganowsky, A. Davin-Regli, E. Moiseeva, M. Zhao, G. Schoehn, and T. Vernet for stimulating discussions. We are indebted to I. Snigireva for scanning electron micrographs and to J.-P. Kleman and F. Lacroix for technical support and advice during epifluorescence microscopy experiments. This work used the platforms of the Grenoble Instruct Center [Integrated Structural Biology Grenoble: Unité mixte de service 3518 CNRS–CEA–UGA–European Molecular Biology Laboratory (EMBL)], with support from the French Infrastructure for Integrated Structural Biology (Grant ANR-10-INSB-05-02) and the Grenoble Alliance for Integrated Structural Cell Biology (GRAL) (Grant ANR-10-LABX-49-01) within the Grenoble Partnership for Structural Biology. The electron microscopy facility is supported by the Rhône-Alpes Region, the Fondation de la Recherche Medicale, the Fonds Européen de Développement Régional, the CNRS, the CEA, the UGA, the EMBL, and the Groupement d’Intérêt Scientifique-Infrastrutures en Biologie, Santé et Agronomie. We are grateful to the ESRF for beam time under the long-term projects MX722, MX1464, and MX1583 (IBS beamtime allocation group). We acknowledge financial support from the CEA, the CNRS, the UGA, Agence Nationale de la Recherche Grant ANR-15-CE18-0005-02 (to J.-P.C.), GRAL Grant C7H-LXG11A20-COLLETIER (to J.-P.C.), Laboratory of Excellence 'Ion Channel Science and Therapeutics' Grant ANR-11-LABX-0015-01 (to M.V.), and Aix-Marseille University and the Service de Santé des Armées (J.-M.P.). M.E.-K. is supported by a joint CEA-GRAL doctoral fellowship (Grant C7H-LXG11A20-DYNAMOP)., ANR-10-INBS-0005,FRISBI,Infrastructure Française pour la Biologie Structurale Intégrée(2010), ANR-10-LABX-0049,GRAL,Grenoble Alliance for Integrated Structural Cell Biology(2010), ANR-11-LABX-0015,ICST,Canaux ioniques d'intérêt thérapeutique(2011), Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Recherche Biomédicale des Armées (IRBA), Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS), rosa, emmanuelle, Infrastructure Française pour la Biologie Structurale Intégrée - - FRISBI2010 - ANR-10-INBS-0005 - INBS - VALID, Grenoble Alliance for Integrated Structural Cell Biology - - GRAL2010 - ANR-10-LABX-0049 - LABX - VALID, Laboratoires d'excellence - Canaux ioniques d'intérêt thérapeutique - - ICST2011 - ANR-11-LABX-0015 - LABX - VALID
المصدر: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (10), pp.E2220-E2228. ⟨10.1073/pnas.1714582115⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2018, 115 (10), pp.E2220-E2228. ⟨10.1073/pnas.1714582115⟩مصطلحات موضوعية: 0301 basic medicine, porins, [SDV.BBM.BS] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], 030106 microbiology, Providencia, 03 medical and health sciences, Extracellular, Cell adhesion, Multidisciplinary, biology, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], Chemistry, Providencia stuartii, Biofilm, steric zippers, cell adhesion, biochemical phenomena, metabolism, and nutrition, biology.organism_classification, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, Transport protein, 030104 developmental biology, Porin, Biophysics, intercellular communication, bacteria, [SDV.MP.BAC] Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, biofilms, Bacterial outer membrane
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c92cbc093eafdb9a571707eef8f12bf
https://hal.science/hal-01894519/document -
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المؤلفون: Chady, Nasrallah, Karine, Rottier, Romain, Marcellin, Vincent, Compan, Joan, Font, Amadeu, Llebaria, Jean-Philippe, Pin, Jean-Louis, Banères, Guillaume, Lebon
المصدر: Scientific Reports
مصطلحات موضوعية: Models, Molecular, Glycosylation, Protein Conformation, Protein Stability, Receptor, Metabotropic Glutamate 5, Heterotrimeric GTP-Binding Proteins, Article, Cell Line, Structure-Activity Relationship, Solubility, Mutation, GTP-Binding Protein alpha Subunits, Gs, Animals, GTP-Binding Protein alpha Subunits, Gq-G11, Humans, Protein Interaction Domains and Motifs, Protein Multimerization, Protein Binding