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المؤلفون: Kevin A. Johnson, Jiri Aubrecht, Elizabeth M. Simpson, Mary E. P. Goad, Charles P. Lerner, Agnieszka K. Czopik, Robert H. Schiestl
المصدر: Drug and Chemical Toxicology. 34:433-439
مصطلحات موضوعية: Genetically modified mouse, Cell Survival, Health, Toxicology and Mutagenesis, Transgene, Drug Resistance, Mice, Transgenic, Biology, Toxicology, Median lethal dose, Lethal Dose 50, Mice, In vivo, Toxicity Tests, Acute, medicine, Animals, Transgenes, Promoter Regions, Genetic, Cells, Cultured, Pharmacology, Chemical Health and Safety, Kanamycin Kinase, Lethal dose, Public Health, Environmental and Occupational Health, Feeder Cells, Gene targeting, General Medicine, Neomycin, Fibroblasts, biochemical phenomena, metabolism, and nutrition, Molecular biology, In vitro, Mice, Inbred C57BL, Blotting, Southern, Gene Targeting, embryonic structures, Gentamicins, Plasmids, medicine.drug
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المؤلفون: Cheryl A. Hill, Charles P. Lerner, Ran Xiao, Jen M. Leszl, Juanliang Cai, David L. Huso, Fan Yang, Kai Yu, Jennifer H. Elisseeff, David M. Ornitz, Joan T. Richtsmeier, Yingli Wang, Baktiar O. Karim, Anthony J. Iacovelli, Ethylin Wang Jabs
المصدر: Development. 132:3537-3548
مصطلحات موضوعية: Mice, Transgenic, Apert syndrome, Biology, Polymorphism, Single Nucleotide, Bone and Bones, Craniosynostosis, Mice, medicine, Animals, Humans, Receptor, Fibroblast Growth Factor, Type 2, Molecular Biology, Bone Development, Fibroblast growth factor receptor 2, Cartilage, Receptor Protein-Tyrosine Kinases, Neural crest, Exons, Anatomy, Acrocephalosyndactylia, medicine.disease, Receptors, Fibroblast Growth Factor, Disease Models, Animal, Sagittal suture, Skull, medicine.anatomical_structure, Amino Acid Substitution, Neurocranium, Mutagenesis, Site-Directed, Developmental Biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f2dc48d30bf020459c2fa0f67969b84
https://doi.org/10.1242/dev.01914 -
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المؤلفون: Beverly Paigen, Xiaosong Wang, Christina Petros, Shelley A. Phelan, Kristina Forsman-Semb, Eric F. Taylor, Charles P. Lerner, Aaron C. Brown
المصدر: Journal of Biological Chemistry. 278:25179-25190
مصطلحات موضوعية: Biology, Protein oxidation, Biochemistry, Superoxide dismutase, Embryonic and Fetal Development, Mice, chemistry.chemical_compound, Paraquat, Glutaredoxin, Animals, Genetic Predisposition to Disease, Molecular Biology, chemistry.chemical_classification, Reactive oxygen species, Peroxiredoxins, Cell Biology, Glutathione, Molecular biology, Oxidative Stress, Peroxidases, chemistry, Catalase, Mutation, biology.protein, Peroxiredoxin, Peroxiredoxin VI
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b5d0fe25df992abc6d2a5070b8943b3
https://doi.org/10.1074/jbc.m302706200 -
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المؤلفون: Haidy Tadros, M. Chrétien, Charles P. Lerner, N Ishida, Nabil G. Seidah, Andrew Chen, M El-Alfy, Y Clermont, Claude Gagnon, Majambu Mbikay, Elizabeth M. Simpson, E De Lamirande
المصدر: Proceedings of the National Academy of Sciences. 94:6842-6846
مصطلحات موضوعية: Male, Proteases, Mutant, Biology, Andrology, Loss of heterozygosity, Mice, Testis, medicine, Animals, Subtilisins, Blastocyst, Allele, Recombination, Genetic, Multidisciplinary, Homozygote, Serine Endopeptidases, Embryogenesis, Biological Sciences, Proprotein convertase, Spermatozoa, Embryonic stem cell, Molecular biology, Mice, Mutant Strains, Fertility, medicine.anatomical_structure, Female, Proprotein Convertases
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13cf03eeae48f784f35396926d205902
https://doi.org/10.1073/pnas.94.13.6842 -
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المؤلفون: Craig A. Leach, Kevin A. Johnson, Thomas R. Ulrich, Elizabeth M. Simpson, Charles P. Lerner, Elizabeth R. Linnell, William C. Rafferty
المصدر: Mammalian Genome. 12:169-171
مصطلحات موضوعية: Male, Genetically modified mouse, Transgene, Drug Resistance, Mice, Transgenic, Biology, Cell Line, Mice, chemistry.chemical_compound, Genetics, Animals, Selection, Genetic, Selectable marker, Reporter gene, Stem Cells, Fibroblasts, Male pronucleus, Molecular biology, Mice, Inbred C57BL, Transgenesis, chemistry, Puromycin, Cell culture, Female, Plasmids
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المؤلفون: Elizabeth M. Simpson, Kevin A. Johnson, Connie L Mahaffey, Kathleen G. Banks, Charles P. Lerner, Roderick T. Bronson
المصدر: Genomics. 82(3)
مصطلحات موضوعية: Genetics, Epididymis, Male, Mice, Knockout, Aging, Retroelements, Retroposon, Mutagenesis (molecular biology technique), Biology, Y chromosome, DNA-Binding Proteins, Mice, Fertility, Essential gene, Knockout mouse, Gene Targeting, Testis, Gene family, Animals, Spermatogenesis, X chromosome
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المؤلفون: Charles P. Lerner, Kevin A. Johnson, Janet K. Bayleran, Ge Y. Fang, Bobbi-Jo Shirley, Elizabeth M. Simpson
المصدر: Genesis (New York, N.Y. : 2000). 33(2)
مصطلحات موضوعية: Genetics, Stem Cells, Gene targeting, Mice, Transgenic, Cell Biology, Biology, Y chromosome, X-inactivation, Germline, Cell Line, Mice, Inbred C57BL, Mice, Endocrinology, medicine.anatomical_structure, Chromosome (genetic algorithm), Gene Duplication, Y Chromosome, Gene duplication, Gene Targeting, medicine, Animals, Inbreeding, Gene, Germ cell
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المؤلفون: Kevin A. Johnson, Arlene H. Sharpe, Charles P. Lerner, Peter W. Laird, Elizabeth M. Simpson, Lena C. Di Lacio
مصطلحات موضوعية: Genetically modified mouse, Molecular Sequence Data, Drug Resistance, Mice, Transgenic, Biology, chemistry.chemical_compound, Mice, Genetics, medicine, Animals, Base sequence, Fibroblast, Cells, Cultured, Base Sequence, Stem Cells, Embryo, DNA, Fibroblasts, Embryonic stem cell, Molecular biology, Mice transgenic, Mice, Inbred C57BL, medicine.anatomical_structure, chemistry, Cinnamates, Stem cell, Hygromycin B
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba47ca650da344ef4bdad0091c7e075b
https://europepmc.org/articles/PMC306843/ -
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المؤلفون: Charles P. Lerner, Chen K. Chai
المصدر: Immunogenetics. 2:363-368
مصطلحات موضوعية: Genetics, medicine.anatomical_structure, Inbred strain, Lymphocyte, Immunology, Backcrossing, medicine, Allele, Biology, Mixed lymphocyte reaction, Human genetics