المؤلفون: McDaniel JM; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Morrissey RL; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Genetics and Epigenetics Graduate Program, The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences, Houston, Texas., Dibra D; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Patel LR; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Xiong S; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Zhang Y; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Texas Southern University, Houston, Texas., Chau GP; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Su X; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Qi Y; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas., El-Naggar AK; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Lozano G; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas.

المصدر: Cancer research communications [Cancer Res Commun] 2024 Aug 01; Vol. 4 (8), pp. 1991-2007.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9918281580506676 Publication Model: Print Cited Medium: Internet ISSN: 2767-9764 (Electronic) Linking ISSN: 27679764 NLM ISO Abbreviation: Cancer Res Commun Subsets: MEDLINE

مواضيع طبية MeSH: Mammary Neoplasms, Experimental*/genetics , Mammary Neoplasms, Experimental*/pathology , Mammary Neoplasms, Experimental*/metabolism , Transcriptome* , Tumor Suppressor Protein p53*/genetics , Tumor Suppressor Protein p53*/metabolism, Animals ; Female ; Humans ; Mice ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic ; Mammary Neoplasms, Animal/genetics ; Mammary Neoplasms, Animal/pathology ; Mammary Neoplasms, Animal/metabolism ; Mutation ; Mutation, Missense ; Triple Negative Breast Neoplasms/genetics ; Triple Negative Breast Neoplasms/pathology

المؤلفون: Dibra D; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Gagea M; Department of Veterinary Medicine & Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas., Qi Y; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Chau GP; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Su X; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Lozano G; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas.

المصدر: Cancer research communications [Cancer Res Commun] 2023 Dec 29; Vol. 3 (12), pp. 2640-2652.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9918281580506676 Publication Model: Print Cited Medium: Internet ISSN: 2767-9764 (Electronic) Linking ISSN: 27679764 NLM ISO Abbreviation: Cancer Res Commun Subsets: MEDLINE

مواضيع طبية MeSH: Non-alcoholic Fatty Liver Disease*/genetics , Carcinoma, Hepatocellular*/genetics , Liver Neoplasms*/genetics, Mice ; Animals ; Tumor Suppressor Protein p53/genetics ; Carcinogenesis/genetics ; Mutation ; Disease Models, Animal ; Obesity/complications

المؤلفون: Yu X; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030., Zhang Y; Department of Pharmaceutical Sciences, Joan M. Lafleur College of Pharmacy and Health Sciences, Texas Southern University, Houston, TX 77004., Xiong S; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030., McDaniel JM; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030., Sun C; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.; Genetics and Epigenetics Program, The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX 77030., Chau GP; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030., Gencel-Augusto J; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.; Genetics and Epigenetics Program, The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX 77030., Chachad D; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.; Genetics and Epigenetics Program, The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX 77030., Morrissey RL; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.; Genetics and Epigenetics Program, The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX 77030., Rao X; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030., Wang J; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030., Lozano G; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Nov 08; Vol. 119 (45), pp. e2210618119. Date of Electronic Publication: 2022 Nov 02.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Breast Neoplasms*/pathology , Phosphatidylinositol 3-Kinases*/genetics , Phosphatidylinositol 3-Kinases*/metabolism, Animals ; Female ; Humans ; Mice ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction/genetics ; TOR Serine-Threonine Kinases/genetics ; TOR Serine-Threonine Kinases/metabolism ; Tumor Suppressor Protein p53/metabolism

المؤلفون: Sun C; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030USA.; Genetics and Epigenetics Program, The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX 77030, USA., Estrella JS; Department of Anatomic Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Whitley EM; Department of Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Chau GP; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030USA., Lozano G; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030USA.; Genetics and Epigenetics Program, The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX 77030, USA., Wasylishen AR; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030USA.

المصدر: Disease models & mechanisms [Dis Model Mech] 2022 Aug 01; Vol. 15 (8). Date of Electronic Publication: 2022 Aug 26.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Company of Biologists Ltd Country of Publication: England NLM ID: 101483332 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1754-8411 (Electronic) Linking ISSN: 17548403 NLM ISO Abbreviation: Dis Model Mech Subsets: MEDLINE

مواضيع طبية MeSH: Islets of Langerhans*/pathology , Neuroendocrine Tumors*/genetics , Pancreatic Neoplasms*/genetics , Pancreatic Neoplasms*/pathology, Adaptor Proteins, Signal Transducing/genetics ; Adaptor Proteins, Signal Transducing/metabolism ; Animals ; Carcinogenesis ; Co-Repressor Proteins ; DNA Helicases ; Humans ; Mental Retardation, X-Linked ; Mice ; Molecular Chaperones ; Nuclear Proteins/genetics ; Nuclear Proteins/metabolism ; X-linked Nuclear Protein/genetics ; alpha-Thalassemia

SCR Disease Name: ATR-X syndrome

المؤلفون: Pant V; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Aryal NK; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Xiong S; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Chau GP; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Fowlkes NW; Department of Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas., Lozano G; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas.

المصدر: Cancer research [Cancer Res] 2022 Apr 01; Vol. 82 (7), pp. 1313-1320.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Fibroblasts*/metabolism , Proto-Oncogene Proteins c-mdm2*/genetics , Proto-Oncogene Proteins c-mdm2*/metabolism, Animals ; Mice ; Mutation ; Protein Binding ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Protein p53/metabolism ; Ubiquitin-Protein Ligases/metabolism

المؤلفون: Wasylishen AR; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Sun C; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; Genetics and Epigenetics Program, The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX 77030, USA., Moyer SM; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; Genetics and Epigenetics Program, The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX 77030, USA., Qi Y; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Chau GP; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Aryal NK; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; Genetics and Epigenetics Program, The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX 77030, USA., McAllister F; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Kim MP; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Barton MC; Genetics and Epigenetics Program, The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX 77030, USA.; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Estrella JS; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Su X; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Lozano G; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; Genetics and Epigenetics Program, The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX 77030, USA.

المصدر: Science advances [Sci Adv] 2020 Aug 05; Vol. 6 (32), pp. eaba8415. Date of Electronic Publication: 2020 Aug 05 (Print Publication: 2020).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: eCollection Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

مواضيع طبية MeSH: Endogenous Retroviruses*/genetics , Neuroendocrine Tumors*/genetics , Neuroendocrine Tumors*/metabolism , Neuroendocrine Tumors*/pathology , Pancreatic Neoplasms*/pathology, Animals ; Cell Plasticity ; Co-Repressor Proteins/genetics ; Mice ; Molecular Chaperones/genetics ; Molecular Chaperones/metabolism ; Nuclear Proteins/genetics ; Nuclear Proteins/metabolism ; X-linked Nuclear Protein/metabolism

المؤلفون: Wasylishen AR; Department of Genetics, University of Texas MD Anderson Cancer Center, Houston, TX 77030., Sun C; Department of Genetics, University of Texas MD Anderson Cancer Center, Houston, TX 77030.; Genetics and Epigenetics Program, The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX 77030., Chau GP; Department of Genetics, University of Texas MD Anderson Cancer Center, Houston, TX 77030., Qi Y; Department of Bioinformatics and Computational Biology, University of Texas MD Anderson Cancer Center, Houston, TX 77030., Su X; Department of Bioinformatics and Computational Biology, University of Texas MD Anderson Cancer Center, Houston, TX 77030., Kim MP; Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030., Estrella JS; Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, TX 77030., Lozano G; Department of Genetics, University of Texas MD Anderson Cancer Center, Houston, TX 77030; gglozano@mdanderson.org.; Genetics and Epigenetics Program, The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX 77030.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Mar 24; Vol. 117 (12), pp. 6622-6629. Date of Electronic Publication: 2020 Mar 10.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Homeostasis*, Carcinogenesis/*pathology , Inflammation/*pathology , Pancreas, Exocrine/*pathology , Pancreatic Neoplasms/*pathology , Pancreatitis/*pathology , Proto-Oncogene Proteins/*physiology, Animals ; Biomarkers/analysis ; Carcinogenesis/immunology ; Carcinogenesis/metabolism ; Carcinoma, Pancreatic Ductal/immunology ; Carcinoma, Pancreatic Ductal/metabolism ; Carcinoma, Pancreatic Ductal/pathology ; Cell Differentiation ; Female ; Gene Expression Regulation ; High-Throughput Nucleotide Sequencing ; Inflammation/immunology ; Inflammation/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mutation ; Pancreas, Exocrine/immunology ; Pancreas, Exocrine/metabolism ; Pancreatic Neoplasms/immunology ; Pancreatic Neoplasms/metabolism ; Pancreatitis/chemically induced ; Pancreatitis/immunology ; Pancreatitis/metabolism ; Proto-Oncogene Proteins c-jun/genetics ; Proto-Oncogene Proteins c-jun/metabolism ; Proto-Oncogene Proteins p21(ras)/genetics

المؤلفون: Wasylishen AR; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Estrella JS; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Pant V; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Chau GP; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Lozano G; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas. gglozano@mdanderson.org.

المصدر: Molecular cancer research : MCR [Mol Cancer Res] 2018 Oct; Vol. 16 (10), pp. 1523-1529. Date of Electronic Publication: 2018 Jun 14.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101150042 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-3125 (Electronic) Linking ISSN: 15417786 NLM ISO Abbreviation: Mol Cancer Res

مواضيع طبية MeSH: Carrier Proteins/*genetics , Intracellular Signaling Peptides and Proteins/*genetics , Neuroendocrine Tumors/*genetics , Nuclear Proteins/*genetics , Pancreatic Neoplasms/*genetics , Tumor Suppressor Protein p53/*genetics, Animals ; Apoptosis/genetics ; Co-Repressor Proteins ; Disease Models, Animal ; Histone Chaperones/genetics ; Histones/genetics ; Humans ; Mice ; Mice, Transgenic ; Molecular Chaperones ; Neuroendocrine Tumors/pathology ; Neuroendocrine Tumors/radiotherapy ; Pancreatic Neoplasms/pathology ; Pancreatic Neoplasms/radiotherapy ; Proto-Oncogene Proteins c-mdm2/genetics ; Radiation Tolerance/genetics ; Signal Transduction/radiation effects ; X-linked Nuclear Protein/genetics

المؤلفون: Iwakuma T; Department of Genetics, Louisiana State University Health Science Center, New Orleans, LA 70112, USA. tiwaku@lsuhsc.edu, Tochigi Y, Van Pelt CS, Caldwell LC, Terzian T, Parant JM, Chau GP, Koch JG, Eischen CM, Lozano G

المصدر: Oncogene [Oncogene] 2008 Mar 20; Vol. 27 (13), pp. 1813-20. Date of Electronic Publication: 2007 Oct 01.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE

مواضيع طبية MeSH: Bone Neoplasms/*pathology , Carrier Proteins/*physiology , Liver Neoplasms/*secondary , Osteosarcoma/*secondary, Animals ; Blotting, Southern ; Bone Neoplasms/metabolism ; Cell Movement ; Female ; Gene Silencing/physiology ; Liver Neoplasms/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Neoplasm Invasiveness ; Osteosarcoma/metabolism ; Phenotype ; Pregnancy ; Proto-Oncogene Proteins c-mdm2/metabolism ; RNA, Messenger/metabolism ; Reverse Transcriptase Polymerase Chain Reaction ; Tumor Suppressor Protein p53/metabolism

المؤلفون: Valentin-Vega YA; Department of Cancer Genetics, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA., Barboza JA, Chau GP, El-Naggar AK, Lozano G

المصدر: Human pathology [Hum Pathol] 2007 Oct; Vol. 38 (10), pp. 1553-62. Date of Electronic Publication: 2007 Jul 24.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: W B Saunders Country of Publication: United States NLM ID: 9421547 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0046-8177 (Print) Linking ISSN: 00468177 NLM ISO Abbreviation: Hum Pathol Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Squamous Cell/*metabolism , Head and Neck Neoplasms/*metabolism , Nuclear Proteins/*metabolism , Proto-Oncogene Proteins/*metabolism, Amino Acid Sequence ; Blotting, Western ; Carcinoma, Squamous Cell/genetics ; Cell Cycle Proteins ; DNA Mutational Analysis ; Gene Expression ; Head and Neck Neoplasms/genetics ; Humans ; Immunohistochemistry ; Molecular Sequence Data ; Mutation ; Nuclear Proteins/genetics ; Proto-Oncogene Proteins/genetics ; Proto-Oncogene Proteins c-mdm2/genetics ; Proto-Oncogene Proteins c-mdm2/metabolism ; Sequence Homology, Amino Acid ; Transfection ; Tumor Suppressor Protein p53/genetics