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1
المؤلفون: Anthony R. Harris, Susan M. Lotarski, Michael Aaron Brodney, Michael Popiolek, Catherine A. Thorn, Stephen Jenkinson, Che Wah Lee, Jennifer E. Davoren, Stefanus J. Steyn, Lei Zhang, Terrence Peter Kenakin, Betty Pettersen, Sarah Grimwood, Damien Webb, Michelle R. Garnsey, Simeon Ramsey, John T. Lazzaro, Steven Victor O'neil, Lisa Nottebaum, Jean-Philippe Fortin, Jeremy R. Edgerton
المصدر: Journal of Medicinal Chemistry. 60:6649-6663
مصطلحات موضوعية: 0301 basic medicine, Agonist, Allosteric modulator, medicine.drug_class, Chemistry, Allosteric regulation, Muscarinic acetylcholine receptor M1, Pharmacology, 03 medical and health sciences, 030104 developmental biology, Drug Discovery, Convulsion, medicine, Molecular Medicine, Cholinergic, Structure–activity relationship, medicine.symptom, Receptor
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2
المؤلفون: Christopher J. Helal, Eric P. Arnold, Tracey L. Boyden, Cheng Chang, Thomas A. Chappie, Kimberly F. Fennell, Michael D. Forman, Mihaly Hajos, John F. Harms, William E. Hoffman, John M. Humphrey, Zhijun Kang, Robin J. Kleiman, Bethany L. Kormos, Erik A. LaChapelle, Che-Wah Lee, Jiemin Lu, Noha Maklad, Laura McDowell, Scot Mente, Rebecca E. O’Connor, Jayvardhan Pandit, Mary Piotrowski, Anne W. Schmidt, Christopher J. Schmidt, Hirokazu Ueno, Patrick R. Verhoest, Edward X. Yang
المصدر: Journal of medicinal chemistry. 61(8)
مصطلحات موضوعية: Drug Discovery, Molecular Medicine
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3
المؤلفون: Jennifer E, Davoren, Michelle, Garnsey, Betty, Pettersen, Michael A, Brodney, Jeremy R, Edgerton, Jean-Philippe, Fortin, Sarah, Grimwood, Anthony R, Harris, Stephen, Jenkinson, Terry, Kenakin, John T, Lazzaro, Che-Wah, Lee, Susan M, Lotarski, Lisa, Nottebaum, Steven V, O'Neil, Michael, Popiolek, Simeon, Ramsey, Stefanus J, Steyn, Catherine A, Thorn, Lei, Zhang, Damien, Webb
المصدر: Journal of medicinal chemistry. 60(15)
مصطلحات موضوعية: Diarrhea, Male, Lactams, Vomiting, Scopolamine, Isoindoles, Structure-Activity Relationship, Dogs, Allosteric Regulation, Piperidines, Seizures, Thiadiazoles, Animals, Humans, Donepezil, Rats, Wistar, Oxazoles, Sulfonamides, Receptor, Muscarinic M1, Mice, Inbred C57BL, Amphetamine, Drug Design, Indans, Microsomes, Liver, Ataxia, Female
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4
المؤلفون: Mina C. Nakhla, John L. Wood, Che-Wah Lee
المصدر: ChemInform. 47
مصطلحات موضوعية: chemistry.chemical_classification, chemistry.chemical_compound, Malonate, chemistry, Ylide, Intramolecular force, Diazo, General Medicine, Ethyl ester, Medicinal chemistry, Decomposition, Catalysis
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5
المؤلفون: John L. Wood, Mina C. Nakhla, Che-Wah Lee
المصدر: Organic letters. 17(23)
مصطلحات موضوعية: chemistry.chemical_classification, Molecular Structure, Chemistry, Organic Chemistry, Esters, Stereoisomerism, Ethyl ester, Biochemistry, Medicinal chemistry, Decomposition, Catalysis, Malonates, chemistry.chemical_compound, Malonate, Ylide, Cyclization, Intramolecular force, Alkynes, Organic chemistry, Diazo, Rhodium, Physical and Theoretical Chemistry
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6
المؤلفون: Hermes Carrero, Che-Wah Lee, Albert J. Fry, Jianxin Gao, James F. Rusling
المصدر: Electrochimica Acta. 45:503-512
مصطلحات موضوعية: Nitrobenzene, chemistry.chemical_compound, chemistry, Bicyclic molecule, Azobenzene, Bromide, General Chemical Engineering, Aryl, Inorganic chemistry, Electrochemistry, Microemulsion, Benzal chloride, Toluene
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7
المؤلفون: Che-Wah Lee, et al. et al.
المصدر: ChemInform. 44
مصطلحات موضوعية: Stereospecificity, Aspartate protease, Chemistry, Stereochemistry, Late stage, Stereoselectivity, General Medicine, Pharmacophore
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8دورية أكاديمية
المؤلفون: Helal, Christopher J., Arnold, Eric, Boyden, Tracey, Cheng Chang, Chang, Cheng, Chappie, Thomas A., Fisher, Ethan, Hajos, Mihaly, Harms, John F., Hoffman, William E., Humphrey, John M., Pandit, Jayvardhan, Kang, Zhijun, Kleiman, Robin J., Kormos, Bethany L., Che-Wah Lee, Jiemin Lu, Maklad, Noha, McDowell, Laura, McGinnis, Dina
المصدر: Journal of Medicinal Chemistry; 2/8/2018, Vol. 61 Issue 3, p1001-1018, 18p
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9دورية أكاديمية
المؤلفون: Davoren, Jennifer E., Garnsey, Michelle, Pettersen, Betty, Brodney, Michael A., Edgerton, Jeremy R., Fortin, Jean-Philippe, Grimwood, Sarah, Harris, Anthony R., Jenkinson, Stephen, Kenakin, Terry, Lazzaro, John T., Che-Wah Lee, Lotarski, Susan M., Nottebaum, Lisa, O'Neil, Steven V., Popiolek, Michael, Ramsey, Simeon, Steyn, Stefanus J., Thorn, Catherine A., Lei Zhang
المصدر: Journal of Medicinal Chemistry; 8/10/2017, Vol. 60 Issue 15, p6649-6663, 15p
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10دورية أكاديمية
المؤلفون: Helal, Christopher J., Arnold, Eric P., Boyden, Tracey L., Cheng Chang, Chappie, Thomas A., Fennell, Kimberly F., Forman, Michael D., Hajos, Mihaly, Harms, John F., Hoffman, William E., Humphrey, John M., Kang, Zhijun, Kleiman, Robin J., Kormos, Bethany L., Che-Wah Lee, Jiemin Lu, Maklad, Noha, McDowell, Laura, Mente, Scot, O'Connor, Rebecca E.
المصدر: Journal of Medicinal Chemistry; Jul2017, Vol. 60 Issue 13, p5673-5698, 26p