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المؤلفون: Shanthakumar R. Tyavanagimatt, Stone Melialani A C L, Kristin A. Wineinger, Eric Stavale, Pietro Scaturro, Dennis E. Hruby, Christine Schneider, Douglas W. Grosenbach, Kara B. Cardwell, Chelsea M. Byrd, Robert Jordan, Jessica M. Page, Kevin F. Jones, Ralf Bartenschlager, Aklile Berhanu, Dongcheng Dai, Chris Harver
المصدر: PubMed Central
مصطلحات موضوعية: Models, Molecular, Viral Plaque Assay, viruses, Molecular Sequence Data, Viremia, Biology, Dengue virus, Virus Replication, medicine.disease_cause, Antiviral Agents, Cell Line, Dengue fever, Dengue, Inhibitory Concentration 50, Mice, 03 medical and health sciences, Dogs, Cricetinae, Chlorocebus aethiops, Thiadiazoles, Escherichia coli, medicine, Animals, Humans, Pharmacology (medical), Amino Acid Sequence, Gene, 030304 developmental biology, Pharmacology, 0303 health sciences, 030306 microbiology, virus diseases, Dengue Virus, Viral Load, biochemical phenomena, metabolism, and nutrition, medicine.disease, Virology, Recombinant Proteins, 3. Good health, Disease Models, Animal, Infectious Diseases, Viral replication, Capsid, Capsid Proteins, Heterocyclic Compounds, 3-Ring, Viral load
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::106293438e92a61421716293edf39a57
https://doi.org/10.1128/aac.01429-12 -
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المؤلفون: Inger K. Damon, Arthur J. Goff, Wendy Johnson, Tove' C. Bolken, John W. Huggins, Chelsea M. Byrd, Eric M. Mucker, Robert Jordan, Kevin L. Karem, Lisa E. Hensley, Nancy A. Twenhafel, Carly Wlazlowski, Dennis E. Hruby, Josh Shamblin, Tom Larsen, Jennifer Chapman
المصدر: Antimicrobial Agents and Chemotherapy. 53:2620-2625
مصطلحات موضوعية: Male, viruses, Isoindoles, Antiviral Agents, Virus, Monkeypox, medicine, Animals, Humans, Pharmacology (medical), Poxviridae, Orthopoxvirus, Smallpox virus, Pharmacology, biology, virus diseases, biology.organism_classification, medicine.disease, Virology, Macaca fascicularis, Infectious Diseases, Benzamides, Immunology, Monkeypox virus, Female, Variola virus, Viral load, Smallpox
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cac489cd0fdd955e7ff09d2a953b23f
https://doi.org/10.1128/aac.00021-09 -
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المؤلفون: Eugene Raush, Vladimir Tseitin, Ruben Abagyan, Vsevolod Katritch, Chelsea M. Byrd, Maxim Totrov, Robert Jordan, Dennis E. Hruby, Dongcheng Dai
المصدر: Journal of Computer-Aided Molecular Design
مصطلحات موضوعية: Models, Molecular, Virtual ligand screening, Binding pocket, Molecular Sequence Data, Drug Evaluation, Preclinical, Drug design, Vaccinia virus, Covalent docking, Cysteine Proteinase Inhibitors, Ligands, Ketone inhibitors, Antiviral Agents, Article, Substrate Specificity, VLS, Structure-Activity Relationship, User-Computer Interface, Drug Discovery, Structure–activity relationship, Computer Simulation, Poxviridae, Amino Acid Sequence, Homology modeling, Physical and Theoretical Chemistry, Binding site, Ubiquitins, Binding Sites, Sequence Homology, Amino Acid, biology, Active site, Ketones, biology.organism_classification, Small molecule, Computer Science Applications, Viral protease, Cysteine Endopeptidases, Biochemistry, Docking (molecular), Drug Design, biology.protein, Smallpox
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المؤلفون: Chelsea M. Byrd, Dennis E. Hruby
المصدر: Drug Development Research
مصطلحات موضوعية: Proteases, Protease, Drug discovery, medicine.drug_class, medicine.medical_treatment, proteinase inhibitors, Research Overview, Research Overviews, Biology, biology.organism_classification, Virology, vaccinia virus, antiviral drugs, I7L, Drug development, Viral replication, Viral life cycle, Drug Discovery, medicine, Orthopoxvirus, Antiviral drug
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المؤلفون: Dennis E. Hruby, Chelsea M. Byrd
المصدر: Microbe Magazine. 1:70-75
مصطلحات موضوعية: chemistry.chemical_classification, Viral nucleic acid, medicine.diagnostic_test, viruses, Proteolysis, biochemical phenomena, metabolism, and nutrition, Biology, Microbiology, Virology, Virus, Enzyme, chemistry, Capsid, Infected cell, medicine
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1fee3169a284ba2f803054eff56a519f
https://doi.org/10.1128/microbe.1.70.1 -
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المؤلفون: Chelsea M. Byrd, Dennis E. Hruby
المصدر: Reviews in Medical Virology
مصطلحات موضوعية: viruses, Proteolysis, Amino Acid Motifs, Reviews, Vaccinia virus, Review, Biology, Virus Replication, Genome, Virus, Viral Proteins, chemistry.chemical_compound, Virology, medicine, Humans, medicine.diagnostic_test, Intracellular parasite, Virion, Infectious Diseases, chemistry, Viral replication, Peptide Hydrolases, Vaccinia
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المؤلفون: Mohan Rao, Robert C. Andrews, Robert Rothlein, Tove' C. Bolken, Murty N. Arimilli, Adnan M. M. Mjalli, Tariq Andrea, Katrina L. Owens, Dennis E. Hruby, Chelsea M. Byrd
المصدر: Journal of Virology. 78:12147-12156
مصطلحات موضوعية: medicine.drug_class, viruses, Molecular Sequence Data, Immunology, Mutant, Orthopoxvirus, Virus Replication, Antiviral Agents, Microbiology, Virus, chemistry.chemical_compound, Virology, Drug Resistance, Viral, Vaccines and Antiviral Agents, medicine, Humans, Poxviridae, Amino Acid Sequence, biology, biology.organism_classification, chemistry, Chordopoxvirinae, Cell culture, Insect Science, Antiviral drug, Vaccinia, HeLa Cells
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::867200c4d3e5550ccf18313468507bbb
https://doi.org/10.1128/jvi.78.22.12147-12156.2004 -
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المؤلفون: Dennis E. Hruby, Tove' C. Bolken, Chelsea M. Byrd
المصدر: Journal of Virology. 76:8973-8976
مصطلحات موضوعية: viruses, Immunology, Replication, Vaccinia virus, Biology, Transfection, Microbiology, Virus, Cell Line, Gene product, chemistry.chemical_compound, Proteinase 3, Virology, Animals, Protein Precursors, Gene, Viral Core Proteins, Genetic Complementation Test, Core protein, Molecular biology, Cysteine Endopeptidases, chemistry, Insect Science, Mutagenesis, Site-Directed, Proteinase activity, Vaccinia, Cysteine
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a490834962881c354c9144b7c3cb38fb
https://doi.org/10.1128/jvi.76.17.8973-8976.2002 -
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المؤلفون: Zach Blackwood, Anthony T. Vella, Kevin F. Jones, Travis K. Warren, Jenny McDonald, David S. King, Chelsea M. Byrd, Tove' C. Bolken, Dennis E. Hruby
المصدر: Vaccine. 20:2197-2205
مصطلحات موضوعية: Interleukin 2, Streptococcus pyogenes, medicine.medical_treatment, Genetic Vectors, Gene Expression, Biology, medicine.disease_cause, Cell Line, Microbiology, law.invention, Interferon-gamma, Mice, Immune system, Antigen, law, Streptococcal Infections, medicine, Animals, Recombination, Genetic, Antigens, Bacterial, Mice, Inbred BALB C, General Veterinary, General Immunology and Microbiology, Streptococcal Vaccines, Vaccination, Public Health, Environmental and Occupational Health, Streptococcus gordonii, Streptococcus, biology.organism_classification, Bacterial vaccine, Infectious Diseases, Cytokine, Antigens, Surface, Recombinant DNA, Interleukin-2, Molecular Medicine, Carrier Proteins, Bacterial Outer Membrane Proteins, medicine.drug
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المؤلفون: Dennis E. Hruby, Douglas W. Grosenbach, Chelsea M. Byrd
المصدر: Current opinion in virology. 3(5)
مصطلحات موضوعية: medicine.medical_specialty, Biodefense, National security, business.industry, Public health, Virology, Antiviral Agents, Bioterrorism, United States, National Institute of Allergy and Infectious Diseases (U.S.), Virus Diseases, Communicable Disease Control, Medicine, Animals, Humans, Public Health, business, Intensive care medicine