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1دورية أكاديمية
المؤلفون: Yehuda Z Cohen, Allison L Butler, Katrina Millard, Maggi Witmer-Pack, Rebeka Levin, Cecilia Unson-O'Brien, Roshni Patel, Irina Shimeliovich, Julio C C Lorenzi, Jill Horowitz, Stephen R Walsh, Shu Lin, Joshua A Weiner, Anna Tse, Alicia Sato, Chelsey Bennett, Bryan Mayer, Kelly E Seaton, Nicole L Yates, Lindsey R Baden, Allan C deCamp, Margaret E Ackerman, Michael S Seaman, Georgia D Tomaras, Michel C Nussenzweig, Marina Caskey
المصدر: PLoS ONE, Vol 14, Iss 8, p e0219142 (2019)
وصف الملف: electronic resource
Relation: https://doaj.org/toc/1932-6203
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المؤلفون: Ramya Nityanandam, Sofia Lupo, Lori F. Maxfield, Georgia D. Tomaras, Alessandra Setaro, Joseph P. Nkolola, Rebecca Zash, Zhilin Chen, Stephen R. Walsh, Dan H. Barouch, Chelsey Bennett, Lisa Sunner, Tyler Cassidy, Kshitij Wagh, Charlotte-Paige Rolle, Frances Priddy, Erica N. Borducchi, Ana N. Monczor, Jinyan Liu, Roberto C. Arduino, Huub C. Gelderblom, Bryan T. Mayer, Diane G. Kanjilal, Abishek Chandrashekar, Elena E. Giorgi, Nicole L. Yates, Edwin DeJesus, Kathryn E. Stephenson, Alicia Sato, Jessica L Ansel, Michael S. Seaman, Joseph Sapiente, C Sabrina Tan, Alan S. Perelson, Bette T. Korber, Allan C. deCamp, Zijin Lin, Boris Julg, Peter Abbink, Lauren Peter
المصدر: Nature Medicine
مصطلحات موضوعية: Adult, CD4-Positive T-Lymphocytes, Male, Phases of clinical research, HIV Infections, HIV Envelope Protein gp120, Placebo, Antiviral Agents, Article, General Biochemistry, Genetics and Molecular Biology, Virus, Placebos, Young Adult, Double-Blind Method, Antiretroviral Therapy, Highly Active, Humans, Medicine, Adverse effect, Retrovirus, biology, business.industry, Antibody titer, General Medicine, Middle Aged, Viral Load, Peptide Fragments, Tolerability, Immunology, HIV-1, biology.protein, Female, Immunotherapy, Antibody, business, Viral load, Broadly Neutralizing Antibodies
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المؤلفون: Chelsey Bennett, Mcclure Megan J, Georgia D. Tomaras, Michael S. Seaman, Clark Rutilio H, Randal R. Ketchem, J. Alaina Floyd, Kelly E. Seaton, Christine C. Siska, Yan Brodsky, Jeremy M. Shaver, Bryan T. Mayer, Nicole L. Yates, Bruce A. Kerwin, Alison J. Gillespie
المصدر: Journal of Pharmaceutical Sciences
مصطلحات موضوعية: analytical biochemistry, HP-SEC, High performance size exclusion chromatography, Protein Conformation, Pharmaceutical Science, CDR, Complementary determining region, 02 engineering and technology, Protein aggregation, HIV Antibodies, 030226 pharmacology & pharmacy, Neutralization, Protein Structure, Secondary, high throughput technology(s), PK, Pharmacokinetic, chemistry.chemical_compound, HC, Heavy chain, Mice, 0302 clinical medicine, Protein structure, protein folding, antibody(s), Gdn-HCl, Guanidine hydrochloride, Chemistry, Protein Stability, fluorescence spectroscopy, 021001 nanoscience & nanotechnology, stabilization, bnAbs, broadly neutralizing antibodies, Monomer, PEG, Polyethylene glycol, DSF, Differential scanning fluorimetry, CDCA, Stability design by covariance analysis, HIV/AIDS, Protein folding, 0210 nano-technology, pharmacokinetics, COGs, Cost of goods, PBS, Phosphate buffered saline, HMW, High molecular weight, Article, physical stability, protein aggregation, 03 medical and health sciences, Residue (chemistry), LC, Light chain, developability, Molecule, Animals, Humans, protein structure, mAb, monoclonal antibody, biopharmaceutical characterization, stability, HEK293 Cells, Mutation, Biophysics, Salt bridge, Broadly Neutralizing Antibodies
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::752f2582d80bda3c1169fc5c9a92aaad
http://europepmc.org/articles/PMC6941225 -
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المؤلفون: B. H. Oakes, Thierry Calandra, Chelsey Bennett, Kathryn E. Foulds, Ralf Wagner, Matthieu Perreau, Mark Parrington, Annette Ives, J. McElrath, Konstantin V. Pugachev, Bertram L. Jacobs, Thierry Roger, Georgia D. Tomaras, Mariano Esteban, Guido Ferrari, Nicole L. Yates, David C. Montefiori, Harold Kleanthous, Mario Roederer, Bryan T. Mayer, Karen V. Kibler, Giuseppe Pantaleo, S. Ding, M. Vaine, Sanjay Phogat, Benedikt Asbach, Beatriz Perdiguero, Shing Fen Kao, Deborah T. Weiss, A. G. Spies, Gregory J. Mize, Jim Tartaglia, Raphael Gottardo, Maryann Giel-Moloney
المساهمون: Bill & Melinda Gates Foundation
المصدر: Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Scientific reports, vol. 9, no. 1, pp. 20005
Scientific Reports
Digital.CSIC. Repositorio Institucional del CSIC
instnameمصطلحات موضوعية: 0301 basic medicine, viruses, Genetic Vectors, Heterologous, lcsh:Medicine, HIV Infections, Cross Reactions, Biology, Article, Virus, law.invention, Mice, 03 medical and health sciences, 0302 clinical medicine, law, Chlorocebus aethiops, Animals, 030212 general & internal medicine, Vector (molecular biology), Neutralizing antibody, lcsh:Science, Vero Cells, AIDS Vaccines, Mice, Inbred BALB C, Vaccines, Synthetic, Multidisciplinary, Virulence, Molecular medicine, Molecular engineering, Flavivirus, Immunogenicity, lcsh:R, Defective Viruses, virus diseases, biology.organism_classification, Antibodies, Neutralizing, Macaca mulatta, Virology, Vaccination, 030104 developmental biology, Preclinical research, HIV-1, biology.protein, Recombinant DNA, Female, lcsh:Q
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c440ba3a669e2a4c5a0e11f58f180f82
http://hdl.handle.net/10261/241086 -
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المؤلفون: Maggi Witmer-Pack, Kelly E. Seaton, Stephen R. Walsh, Chelsey Bennett, Joshua A. Weiner, Julio C. C. Lorenzi, Irina Shimeliovich, Alicia Sato, Roshni Patel, Cecilia Unson-O’Brien, Nicole L. Yates, Allison L. Butler, Lindsey R. Baden, Jill Horowitz, Marina Caskey, Georgia D. Tomaras, Michel C. Nussenzweig, Yehuda Z. Cohen, Bryan T. Mayer, Margaret E. Ackerman, Allan C. deCamp, Michael S. Seaman, Rebeka Levin, Katrina G. Millard, Anna Tse, Shu Lin
المصدر: PLoS ONE, Vol 14, Iss 8, p e0219142 (2019)
PLoS ONEمصطلحات موضوعية: Male, RNA viruses, 0301 basic medicine, Physiology, Antibody Response, HIV Infections, HIV Antibodies, Pathology and Laboratory Medicine, Biochemistry, law.invention, Pre-exposure prophylaxis, 0302 clinical medicine, Immunodeficiency Viruses, Randomized controlled trial, law, Immune Physiology, HIV Seropositivity, Medicine and Health Sciences, Medicine, Public and Occupational Health, 030212 general & internal medicine, Enzyme-Linked Immunoassays, Immune Response, Immune System Proteins, Multidisciplinary, Pharmaceutics, Immunogenicity, Antibodies, Monoclonal, Healthy Volunteers, 3. Good health, Tolerability, Research Design, Medical Microbiology, Viral Pathogens, Viruses, Administration, Intravenous, Drug Therapy, Combination, Female, Pathogens, Research Article, Adult, medicine.medical_specialty, Drug Administration, Clinical Research Design, Science, Immunology, Antibodies, Monoclonal, Humanized, Research and Analysis Methods, Placebo, Microbiology, Antibodies, 03 medical and health sciences, Double-Blind Method, Drug Therapy, Pharmacokinetics, Internal medicine, Retroviruses, Humans, Immunoassays, Adverse effect, Microbial Pathogens, Pharmacology, Prophylaxis, business.industry, Lentivirus, Organisms, Biology and Life Sciences, Proteins, HIV, Placebo Effect, Clinical trial, 030104 developmental biology, HIV-1, Immunologic Techniques, Pre-Exposure Prophylaxis, Adverse Events, Preventive Medicine, business, Broadly Neutralizing Antibodies
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