المؤلفون: Carlos Sanjuan, Fernando Rodríguez de Fonseca, Francisco Javier Pavón, Rubén Tovar, Elena Baixeras, Juan Antonio Navarro, Cristina Rosell-Valle, Alfonso Gutiérrez-Adán, Juan Carlos Ledesma, Dina Medina-Vera, Juan Decara

المساهمون: Ministerio de Economía y Competitividad (España), Instituto de Salud Carlos III, Junta de Andalucía, Medina-Vera, D, Navarro, JA, Tovar, R, Rosell-Valle, C, Gutiérrez-Adán, Alfonso, Ledesma, JC, Sanjuan, C, Pavon, FJ, Baixeras, E, de Fonseca, FR, Decara, J, [Medina-Vera,D, Navarro,JA, Tovar,R, Rosell-Valle,C, Ledesma,JC¸ Pavón,FJ, Rodríguez de Fonseca,F, Decara,J] Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Universitario Regional de Málaga, UGC Salud Mental, Málaga, Spain. [Medina-Vera,D] Facultad de Ciencias, Universidad de Málaga, Málaga, Spain. [Medina-Vera,D, Tovar,R] Facultad de Medicina, Universidad de Málaga, Málaga, Spain. [Pavón,FJ] Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), UGC del Corazón, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Universitario Virgen de la Victoria, Universidad de Málaga, Málaga, Spain. [Gutiérrez-Adan,A] Departamento de Reproducción Animal, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria, Madrid, Spain. [Sanjuan,C] Euronutra S.L. Málaga, Spain. [Baixeras,E] Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Universidad de Málaga, Málaga, Spain., This work was supported by grants from the following institutions: Ministerio de Economía y Competitividad, Gobierno de España (Grant RTC-2016-4983-1), EU-ERDF-Instituto de Salud Carlos III (Grant PI19/01577), and Consejería de Economía, Conocimiento y Universidad, Junta de Andalucía (Grant P18-TP-5194), Proyecto de Investigación en Salud, Consejería de Salud y Familias (PI-0139-2018). D.M-V. (FI20/00227) holds a 'PFIS' predoctoral contract from the National System of Health, EU-ERDF-Instituto de Salud Carlos III., Medina-Vera, D [0000-0002-0342-1287], Navarro, JA [0000-0003-3089-0983], Tovar, R [0000-0002-4517-8932], Rosell-Valle, C [0000-0001-9545-0976], Gutierrez-Adan, A [0000-0001-9893-9179], Ledesma, JC [0000-0001-6372-2842], Sanjuan, C [0000-0003-3505-0481], Pavon, FJ [0000-0002-5256-8904], Baixeras, E [0000-0001-6955-2434], de Fonseca, FR [0000-0002-4516-5795], Decara, J [0000-0002-9868-015X]

المصدر: Nutrients, Vol 13, Iss 2268, p 2268 (2021)
Nutrients
Volume 13
Issue 7
Digital.CSIC. Repositorio Institucional del CSIC
instname

مصطلحات موضوعية: 0301 basic medicine, Blood Glucose, Male, medicine.medical_treatment, Phenomena and Processes::Physiological Phenomena::Pharmacological Phenomena::Drug Resistance::Insulin Resistance [Medical Subject Headings], Administration, Oral, 0302 clinical medicine, insulin resistance, Organisms::Eukaryota::Animals [Medical Subject Headings], Homeostasis, Insulin, TX341-641, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Rats::Rats, Wistar [Medical Subject Headings], hypothalamus, Insulin-Like Growth Factor I, Phosphorylation, D-Pinitol, Nutrition and Dietetics, biology, Chemistry, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Drug Therapy::Drug Administration Routes::Administration, Oral [Medical Subject Headings], Hypothalamus, PI3K/Akt pathway, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intercellular Signaling Peptides and Proteins::Somatomedins::Insulin-Like Growth Factor I [Medical Subject Headings], Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Phosphotransferases::Phosphotransferases (Alcohol Group Acceptor)::Phosphatidylinositol 3-Kinases::Phosphatidylinositol 3-Kinase [Medical Subject Headings], Signal Transduction, Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Peptide Hormones::Pancreatic Hormones::Proglucagon::Glucagon [Medical Subject Headings], medicine.medical_specialty, Resistencia a la insulina, Article, Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Enzyme Activation [Medical Subject Headings], 03 medical and health sciences, Ratas, Insulin resistance, Internal medicine, Proteínas proto-oncogénicas c-akt, medicine, Animals, Rats, Wistar, Protein kinase B, PI3K/AKT/mTOR pathway, Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Peptide Hormones::Pancreatic Hormones::Insulins [Medical Subject Headings], Chemicals and Drugs::Organic Chemicals::Alcohols::Sugar Alcohols::Inositol [Medical Subject Headings], Nutrition. Foods and food supply, Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Signal Transduction [Medical Subject Headings], Anatomy::Nervous System::Central Nervous System::Brain::Limbic System::Hypothalamus [Medical Subject Headings], medicine.disease, Glucagon, Enzyme Activation, Insulin receptor, 030104 developmental biology, Endocrinology, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Rats [Medical Subject Headings], inositol, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Neoplasm Proteins::Oncogene Proteins::Proto-Oncogene Proteins::Proto-Oncogene Proteins c-akt [Medical Subject Headings], biology.protein, Phenomena and Processes::Chemical Phenomena::Organic Chemistry Phenomena::Organic Chemistry Processes::Phosphorylation [Medical Subject Headings], Phosphatidylinositol 3-Kinase, Phenomena and Processes::Physiological Phenomena::Physiological Processes::Homeostasis [Medical Subject Headings], Proto-Oncogene Proteins c-akt, 030217 neurology & neurosurgery, Hipotálamo, Food Science, Hormone, Fosfatidilinositol 3-quinasas, Chemicals and Drugs::Carbohydrates::Monosaccharides::Hexoses::Glucose::Blood Glucose [Medical Subject Headings]

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a6f7208e0418bfddcd932e70b45de7a
https://hdl.handle.net/10668/18130

المؤلفون: Rodríguez-Hernández, María A., Cruz, Patricia de la, López-Grueso, M. José, Navarro-Villarán, Elena, Requejo-Aguilar, Raquel, Castejón Vega, Beatriz, Negrete, María, Gallego, Paloma, Vega-Ochoa, Álvaro, Victor, Víctor M., Cordero, Mario D., Campo, José A. del, Bárcena, J. Antonio, Padilla, Alicia C., Muntané, Jordi

المساهمون: [Rodríguez-Hernández,A, de la Cruz-Ojeda,P, Navarro-Villarán,E, Negrete,M, Vega-Ochoa,A, Muntané,J] Institute of Biomedicine of Seville (IBiS), IBiS/Hospital University 'Virgen del Rocío'/CSIC/University of Seville, Seville, Spain. [Rodríguez-Hernández,A, Victor,VM, Muntané,J] Centro de Investigación Biomédica en red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, Spain. [López-Grueso,MJ, Requejo-Aguilar,R, Bárcena,JA, Padilla,CA] Department of Biochemistry and Molecular Biology, University of Cordoba, Maimonides Biomedical Research Institute of Cordoba (IMIBIC), Cordoba, Spain. [Castejón-Vega,B, Cordero,MD] Research Laboratory, Oral Medicine Department, University of Seville, Seville, Spain. [Gallego,P, Del Campo,JA] Unit for the Clinical Management of Digestive Diseases, Hospital University 'Nuestra Señora de Valme', Sevilla, Spain. [Victor,VM] Service of Endocrinology and Nutrition, Hospital University 'Doctor Peset', Foundation for the Promotion of Health and Biomedical Research in the Valencian Region (FISABIO), Valencia, Spain. [Victor,VM] Department of Physiology, University of Valencia, Valencia, Spain. [Cordero,MD] Department of Physiology, Institute of Nutrition and Food Technology 'José Mataix', Biomedical Research Center (CIBM), University of Granada, Armilla, Spain. [Muntané,J] Department of General Surgery, Hospital University 'Virgen del Rocío'/IBiS/CSIC/University of Seville, Seville, Spain., This study was funded by Institute of Health Carlos III (ISCiii) (PI16/00090, PI19/00838 and PI19/01266), Spanish Ministry of Economy and Competitiveness (BFU2016-80006-P), Andalusian Ministry of Economy, Innovation, Science and Employment (BIO-216 and CTS-6264), Andalusian Ministry of Equality, Health and Social Policies (PI-0198-2016) and Valencian Ministry of Education, Culture and Sports (PROMETEO/2019/027). P de la C-O was supported by FPU predoctoral fellowship (FPU17/00026) from Spanish Ministry of Education, Culture and Sports. E N-V was supported by the the predoctoral i-PFIS IIS-enterprise contract in science and technologies in health (IFI18/00014) from ISCiii., Instituto de Salud Carlos III, Junta de Andalucía, Generalitat Valenciana, Red Temática de Investigación Cooperativa en Enfermedades Cardiovasculares (España), Centro de Investigación Biomédica en Red Enfermedades Hepáticas y Digestivas (España), European Commission, Ministerio de Economía y Competitividad (España)

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname

مصطلحات موضوعية: Cell death, Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Enzyme Inhibitors::Protein Kinase Inhibitors [Medical Subject Headings], PGC-1α, Autofagia, Phenomena and Processes::Cell Physiological Phenomena::Cellular Microenvironment::Tumor Microenvironment [Medical Subject Headings], Estrés del retículo endoplásmico, Diseases::Neoplasms [Medical Subject Headings], Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Intracellular Signaling Peptides and Proteins::Proto-Oncogene Proteins c-akt [Medical Subject Headings], Muerte celular, Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death::Apoptosis [Medical Subject Headings], Oxidación-reducción, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], Redox status, Autophagy, Endoplasmic reticulum stress, mTOR, Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death::Autophagy [Medical Subject Headings], Serina-treonina quinasas TOR, Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Phosphotransferases::Phosphotransferases (Alcohol Group Acceptor)::Phosphatidylinositol 3-Kinases::Phosphatidylinositol 3-Kinase [Medical Subject Headings], Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Mitochondria [Medical Subject Headings]

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b7b8f33c8aa2664f525930342df89417
https://hdl.handle.net/10668/3608

المؤلفون: Julieta Maymó, Antonio Pérez-Pérez, Manuel Fernández-Sánchez, José Luis Dueñas, Cecilia L. Varone, Víctor Sánchez-Margalet, Pilar Guadix

المساهمون: [Pérez-Pérez,A, Sánchez-Margalet,V] Department of Medical Biochemistry and Molecular Biology, School of Medicine, Virgen Macarena University Hospital, Seville, Spain. [Guadix,P, Dueñas,JL] Obstetrics and Gynecology Service, Virgen Macarena University Hospital, Seville, Spain. [Maymó,J, Varone,C] Department of Biological Chemistry, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina. [Fernández-Sánchez,M] IVI Seville, Seville, Spain.

مصطلحات موضوعية: Leptin, Placenta, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Clinical Biochemistry, Biochemistry, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], Endocrinology, Pregnancy, Insulin, PLACENTA, Phosphorylation, Diseases::Female Urogenital Diseases and Pregnancy Complications::Pregnancy Complications::Diabetes, Gestational [Medical Subject Headings], Phenomena and Processes::Reproductive and Urinary Physiological Phenomena::Reproductive Physiological Phenomena::Reproductive Physiological Processes::Reproduction::Pregnancy [Medical Subject Headings], Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Phosphotransferases::Phosphotransferases (Alcohol Group Acceptor)::Protein Kinases::Protein-Serine-Threonine Kinases::Mitogen-Activated Protein Kinases [Medical Subject Headings], Anatomy::Cells::Endocrine Cells::Trophoblasts [Medical Subject Headings], biology, Trofoblastos, digestive, oral, and skin physiology, SIGNAL TRANSDUCTION, Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Signal Transduction [Medical Subject Headings], General Medicine, Immunohistochemistry, INSULIN, GESTATIONAL DIABETES, medicine.anatomical_structure, embryonic structures, Receptors, Leptin, Female, Proteínas quinasas activadas por mitógenos, Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Phosphotransferases::Phosphotransferases (Alcohol Group Acceptor)::Phosphatidylinositol 3-Kinases::Phosphatidylinositol 3-Kinase [Medical Subject Headings], hormones, hormone substitutes, and hormone antagonists, CIENCIAS NATURALES Y EXACTAS, Signal Transduction, Adult, medicine.medical_specialty, Insulin Receptor Substrate Proteins, Otras Ciencias Biológicas, Down-Regulation, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, Adipokine::Receptors, Leptin [Medical Subject Headings], Models, Biological, Ciencias Biológicas, LEPTIN, Downregulation and upregulation, Internal medicine, medicine, Humans, Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Peptide Hormones::Adipokines::Leptin [Medical Subject Headings], Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Peptide Hormones::Pancreatic Hormones::Insulins [Medical Subject Headings], Leptin receptor, Dose-Response Relationship, Drug, Biochemistry (medical), Trophoblast, Receptor, Insulin, Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Phosphotransferases::Phosphotransferases (Alcohol Group Acceptor)::Protein Kinases::Protein-Tyrosine Kinases::Receptor Protein-Tyrosine Kinases::Receptor, Insulin [Medical Subject Headings], Diabetes, Gestational, Insulin receptor, Check Tags::Female [Medical Subject Headings], Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Phosphotransferases::Phosphotransferases (Alcohol Group Acceptor)::Protein Kinases::Protein-Tyrosine Kinases::Janus Kinases::Janus Kinase 2 [Medical Subject Headings], Case-Control Studies, biology.protein, Fosfatidilinositol 3-Quinasas

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2c60aad395b05e6ce785350711c1238
https://www.thieme-connect.de/DOI/DOI?10.1055/s-0035-1559722

المؤلفون: Moreno Nogueira, J A, Valero Arbizu, M, Pérez Temprano, R

المساهمون: [Moreno Nogueira,JA] Department of Oncology, Virgen del Rocio University Hospital. Royal Academy of Medicine, Seville, Spain. [Valero Arbizu,M] Department of Oncology, Infanta Luisa Hospital, Seville, Spain. [Pérez Temprano,R] Department of Medicine, Virgen Macarena University Hospital, Seville, Spain.

المصدر: ISRN Dermatology.

مصطلحات موضوعية: Recurrencia local de neoplasia, Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Recurrence [Medical Subject Headings], Article Subject, Diseases::Neoplasms::Neoplasms by Site::Skin Neoplasms [Medical Subject Headings], Proliferación de la célula, Ganglios linfáticos, Diseases::Neoplasms::Neoplastic Processes::Neoplasm Recurrence, Local [Medical Subject Headings], Diseases::Neoplasms::Neoplasms by Histologic Type::Neoplasms, Germ Cell and Embryonal::Neuroectodermal Tumors::Neuroendocrine Tumors::Melanoma [Medical Subject Headings], Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], Analytical, Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures, Operative::Lymph Node Excision [Medical Subject Headings], Interferón-alfa, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis [Medical Subject Headings], Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intercellular Signaling Peptides and Proteins::Cytokines::Interferons::Interferon Type I::Interferon-alpha [Medical Subject Headings], Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Growth Processes::Cell Proliferation [Medical Subject Headings], Melanoma, Anatomy::Tissues::Lymphoid Tissue::Lymph Nodes [Medical Subject Headings], Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Phosphotransferases::Phosphotransferases (Alcohol Group Acceptor)::Phosphatidylinositol 3-Kinases::Phosphatidylinositol 3-Kinase [Medical Subject Headings], neoplasms, Fosfatidilinositol 3-quinasas

وصف الملف: text/xhtml; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::bacd5f01f9dae782c2694d8cc3d4f1c4