-
1
المؤلفون: Ting Jen Cheng, David S. Goodsell, Chen Chen Kan
المصدر: Letters in Drug Design & Discovery. 2:364-371
مصطلحات موضوعية: chemistry.chemical_compound, Biochemistry, Chemistry, High-throughput screening, Drug Discovery, Pharmaceutical Science, Molecular Medicine, HIV Protease Inhibitor, Identification (biology), Sanguinarine, Molecular biology, Cell based
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::47aac718b2e1849859821aa79bca4f01
https://doi.org/10.2174/1570180054405811 -
2
المؤلفون: Ashraf Brik, Ting-Jen Cheng, Chi-Huey Wong, Chen-Chen Kan
المصدر: Antimicrobial Agents and Chemotherapy. 48:2437-2447
مصطلحات موضوعية: Proteases, Cost-Benefit Analysis, medicine.medical_treatment, Blotting, Western, Drug Evaluation, Preclinical, Biology, Antiviral Agents, Microbiology, Amprenavir, Escherichia coli, medicine, Virus maturation, Humans, HIV Protease Inhibitor, Pharmacology (medical), Protease inhibitor (pharmacology), Pharmacology, Protease, Dose-Response Relationship, Drug, Reverse Transcriptase Polymerase Chain Reaction, Reproducibility of Results, virus diseases, Galactosidase activity, HIV Protease Inhibitors, beta-Galactosidase, Amides, Virology, NS2-3 protease, Infectious Diseases, Mutagenesis, HIV-1, Plasmids, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::290c50f02214ac5ab6d77e281a1b883c
https://doi.org/10.1128/aac.48.7.2437-2447.2004 -
3
المؤلفون: Peter G. Rey, Thomas Poon, Ting-Jen Cheng, Chen-Chen Kan
المصدر: European Journal of Biochemistry. 269:3697-3704
مصطلحات موضوعية: chemistry.chemical_classification, Mutation, biology, Topoisomerase, Phosphodiesterase, medicine.disease_cause, Biochemistry, Molecular biology, law.invention, chemistry.chemical_compound, Enzyme, chemistry, law, biology.protein, medicine, Recombinant DNA, Enzyme kinetics, DNA, Camptothecin, medicine.drug
-
4
المؤلفون: Yali Deng, Patrick M O'Connor, Chen-Chen Kan, Pamela Myers, James Register, Luo Chun, Stephen Margosiak, Binh Nguyen, Kevin Ryan, Ping Chen, Karen Lundgren, Anna Tempczyk-Russell
المصدر: Cell. 100(6):681-692
مصطلحات موضوعية: Cyclin-dependent kinase 1, animal structures, Biochemistry, Genetics and Molecular Biology(all), genetic processes, Cyclin-dependent kinase 2, Cyclin-dependent kinase 3, Biology, environment and public health, General Biochemistry, Genetics and Molecular Biology, MAP2K7, Cell biology, enzymes and coenzymes (carbohydrates), Cyclin-dependent kinase complex, biology.protein, biological phenomena, cell phenomena, and immunity, Kinase activity, Casein kinase 2, Cyclin-dependent kinase 7
-
5
المؤلفون: Michele Ann Mctigue, Michael R Gehring, Chris Pinko, J. Ernest Villafranca, Chen-Chen Kan, Camran V Parast, Krzysztof Appelt, Richard E. Showalter, Barbara Mroczkowski, John A Wickersham, Anna Tempczyk-Russell
المصدر: Structure. 7:319-330
مصطلحات موضوعية: Models, Molecular, Protein Folding, Protein Conformation, Recombinant Fusion Proteins, Molecular Sequence Data, Neovascularization, Physiologic, Mitogen-activated protein kinase kinase, Crystallography, X-Ray, Protein Structure, Secondary, Receptor tyrosine kinase, Substrate Specificity, MAP2K7, angiogenesis, Structure-Activity Relationship, kinase insert domain, Adenosine Triphosphate, Structural Biology, Catalytic Domain, Humans, Receptors, Growth Factor, ASK1, Amino Acid Sequence, Kinase activity, Growth Substances, Molecular Biology, Binding Sites, Sequence Homology, Amino Acid, biology, MAP kinase kinase kinase, tyrosine kinase, Receptor Protein-Tyrosine Kinases, Protein-Tyrosine Kinases, Peptide Fragments, Cell biology, Kinetics, Receptors, Vascular Endothelial Growth Factor, Biochemistry, Multigene Family, Mutagenesis, Site-Directed, biology.protein, Cyclin-dependent kinase 9, X-ray structure, Sequence Alignment, signal transduction, Proto-oncogene tyrosine-protein kinase Src
-
6
المؤلفون: Chen-Chen Kan, Ko Suzuki, Keith Brew, Hideaki Nagase, Wen Hung, Michael R. Gehring
المصدر: bchm. 379:185-192
مصطلحات موضوعية: Matrix Metalloproteinase 3, Recombinant Fusion Proteins, Clinical Biochemistry, Gene Expression, Matrix metalloproteinase, medicine.disease_cause, Biochemistry, chemistry.chemical_compound, Escherichia coli, medicine, Humans, Protease Inhibitors, Protein precursor, Molecular Biology, Sequence Deletion, chemistry.chemical_classification, Enzyme Precursors, Metalloproteinase, Tissue Inhibitor of Metalloproteinase-1, Tissue inhibitor of metalloproteinase, Cell biology, Amino acid, Enzyme Activation, EGTA, chemistry
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aacf20d3a95914e7bad543dbc902b31
https://doi.org/10.1515/bchm.1998.379.2.185 -
7
المؤلفون: Tom K Huffaker, Leora S. Zalman, Susan L. Binford, Amy K. Patick, Christopher Pinko, Chen-Chen Kan
المصدر: Antiviral Research. 33:215-218
مصطلحات موضوعية: Human cytomegalovirus, Genes, Viral, viruses, medicine.medical_treatment, Cytomegalovirus, Drug resistance, Biology, medicine.disease_cause, Virus, Cell Line, Viral Proteins, Species Specificity, Virology, Endopeptidases, medicine, Humans, skin and connective tissue diseases, Gene, Pharmacology, chemistry.chemical_classification, Mutation, Binding Sites, Protease, Serine Endopeptidases, Nucleic acid sequence, medicine.disease, Amino acid, chemistry, Cytomegalovirus Infections, sense organs
-
8
المؤلفون: H. E. Van Wart, Christopher M. Holman, A. Welch, Michelle F. Browner, § Chen-Chen Kan, M. R. Gehring
المصدر: Archives of Biochemistry and Biophysics. 324:59-64
مصطلحات موضوعية: Protein Folding, Recombinant Fusion Proteins, Molecular Sequence Data, Biophysics, Peptide, CHO Cells, Biochemistry, Chromatography, Affinity, Enzyme activator, Affinity chromatography, Cricetinae, Escherichia coli, Animals, Humans, Amino Acid Sequence, Enzyme kinetics, Matrilysin, Molecular Biology, Peptide sequence, Fluorescent Dyes, chemistry.chemical_classification, Chromatography, Base Sequence, Chemistry, Hydrolysis, Chinese hamster ovary cell, Metalloendopeptidases, Substrate (chemistry), Enzyme Activation, Kinetics, Matrix Metalloproteinase 7, Crystallization, Oligopeptides
-
9
المؤلفون: Vanderpool Darin Louis, Jeanine C. Gutowski, Brad Condon, Christopher Pinko, Chen-Chen Kan, Stephen Margosiak
المصدر: Journal of Biological Chemistry. 270:23634-23640
مصطلحات موضوعية: Alanine, chemistry.chemical_classification, Protease, medicine.medical_treatment, Peptide, Cell Biology, Biology, Cleavage (embryo), medicine.disease_cause, Biochemistry, Molecular biology, law.invention, chemistry, law, medicine, Recombinant DNA, Enzyme kinetics, Protein precursor, Molecular Biology, Escherichia coli
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::dc2e0754445cc70738faa800343599b7
https://doi.org/10.1074/jbc.270.40.23634 -
10
المؤلفون: Stephen A. Margosiak, Michael R. Gehring, Brad Condon, Chen-Chen Kan
المصدر: Journal of Biological Chemistry. 270:22507-22513
مصطلحات موضوعية: animal structures, MMP1, Phenylalanine, Recombinant Fusion Proteins, Molecular Sequence Data, Biology, Cleavage (embryo), medicine.disease_cause, Biochemistry, Substrate Specificity, Cistron, Escherichia coli, medicine, Humans, Amino Acid Sequence, Collagenases, Ubiquitins, Molecular Biology, Binding Sites, Expression vector, Base Sequence, integumentary system, Valine, Cell Biology, Fibroblasts, Fusion protein, Molecular biology, Molecular Weight, Solubility, embryonic structures, Collagenase, Matrix Metalloproteinase 1, Linker, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::860aba942711fcd32d5c72f0bd1bd1a1
https://doi.org/10.1074/jbc.270.38.22507