المؤلفون: Cameron, DP, Grosser, J, Ladigan, S, Kuzin, V, Iliopoulou, E, Wiegard, A, Benredjem, H, Jackson, K, Liffers, ST, Lueong, S, Cheung, PF, Vangala, D, Pohl, M, Viebahn, R, Teschendorf, C, Wolters, H, Usta, S, Geng, KY, Kutter, C, Arsenian-Henriksson, M, Siveke, JT, Tannapfel, A, Schmiegel, W, Hahn, SA, Baranello, L

المصدر: Science advances. 9(41)

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:154027980

المؤلفون: Filippini, Dea, Christian, Neander, Delfino, Pietro, Cheung, Pf, Sabrina, D’Agosto, Fiorini, Elena, Lupo, Francesca, Fiorini, Claudia, Rusev, Borislav Chavdarov, DE SANCTIS, Francesco, Simbolo, Michele, Ugel, Stefano, Bronte, Vincenzo, Fassan, Matteo, Lawlor, Rita Teresa, Barbi, Stefano, Scarpa, Aldo, Jens, Siveke, Corbo, Vincenzo

مصطلحات موضوعية: microenvironment, macrophages, pancreatic cancer, MAP kinase, mouse, pancreatic cancer, MAP kinase, Settore MED/08 - Anatomia Patologica, microenvironment, mouse, macrophages

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______1943::8903be460097848f93a17ef4c6cb8d7f
http://hdl.handle.net/11562/995029

المؤلفون: Lu IN; Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Münster, Germany., Cheung PF; Spatiotemporal Tumor Heterogeneity, German Cancer Consortium (DKTK), Partner Site Essen, A Partnership Between German Cancer Research Center (DKFZ) and University Hospital Essen, Essen, Germany.; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, DKTK, Partner Site Essen, A Partnership Between German Cancer Research Center (DKFZ) and University Hospital Essen, Essen, Germany., Heming M; Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Münster, Germany., Thomas C; Institute of Neuropathology, University Hospital Münster, Münster, Germany., Giglio G; Spatiotemporal Tumor Heterogeneity, German Cancer Consortium (DKTK), Partner Site Essen, A Partnership Between German Cancer Research Center (DKFZ) and University Hospital Essen, Essen, Germany.; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, DKTK, Partner Site Essen, A Partnership Between German Cancer Research Center (DKFZ) and University Hospital Essen, Essen, Germany., Leo M; Department of Neurology and Center for Translational Neuro and Behavioral Science, University Hospital Essen, Essen, Germany., Erdemir M; Department of Neurology and Center for Translational Neuro and Behavioral Science, University Hospital Essen, Essen, Germany., Wirth T; Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Münster, Germany., König S; Core Unit Proteomics, Interdisciplinary Center for Clinical Research, University of Münster, Münster, Germany., Dambietz CA; Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Münster, Germany., Schroeter CB; Department of Neurology, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Nelke C; Department of Neurology, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Siveke JT; Spatiotemporal Tumor Heterogeneity, German Cancer Consortium (DKTK), Partner Site Essen, A Partnership Between German Cancer Research Center (DKFZ) and University Hospital Essen, Essen, Germany.; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, DKTK, Partner Site Essen, A Partnership Between German Cancer Research Center (DKFZ) and University Hospital Essen, Essen, Germany., Ruck T; Department of Neurology, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Klotz L; Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Münster, Germany., Haider C; Division of Neuropathology and Neurochemistry, Medical University of Vienna, Vienna, Austria.; Comprehensive Center for Clinical Neurosciences and Mental Health, Medical University of Vienna, Vienna, Austria., Höftberger R; Division of Neuropathology and Neurochemistry, Medical University of Vienna, Vienna, Austria.; Comprehensive Center for Clinical Neurosciences and Mental Health, Medical University of Vienna, Vienna, Austria., Kleinschnitz C; Department of Neurology and Center for Translational Neuro and Behavioral Science, University Hospital Essen, Essen, Germany., Wiendl H; Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Münster, Germany., Hagenacker T; Department of Neurology and Center for Translational Neuro and Behavioral Science, University Hospital Essen, Essen, Germany. tim.hagenacker@uk-essen.de., Meyer Zu Horste G; Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Münster, Germany. gerd.meyerzuhoerste@ukmuenster.de.

المصدر: Nature communications [Nat Commun] 2024 May 15; Vol. 15 (1), pp. 4120. Date of Electronic Publication: 2024 May 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Oligonucleotides* , Muscular Atrophy, Spinal*/drug therapy , Muscular Atrophy, Spinal*/pathology , Muscular Atrophy, Spinal*/genetics , Motor Neurons*/drug effects , Motor Neurons*/pathology , Motor Neurons*/metabolism , Killer Cells, Natural*/immunology , Killer Cells, Natural*/drug effects , Brain*/pathology , Brain*/drug effects, Humans ; Female ; Male ; Survival of Motor Neuron 2 Protein/genetics ; CD8-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/drug effects ; Survival of Motor Neuron 1 Protein/genetics ; Survival of Motor Neuron 1 Protein/metabolism ; Single-Cell Analysis ; Cytotoxicity, Immunologic/drug effects ; Infant ; Child, Preschool ; Child ; Transcriptome

المؤلفون: Huang D; Department of Chemical Pathology, The Chinese University of Hong Kong, Hong Kong, China., Liu X; Department of Dermatology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China., Gao X; Department of Chemical Pathology, The Chinese University of Hong Kong, Hong Kong, China.; Center of Clinical Laboratory Medicine, Zhongda Hospital, Southeast University, Nanjing, China., Choi CK; Department of Chemical Pathology, The Chinese University of Hong Kong, Hong Kong, China., Giglio G; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, partner site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany., Farah L; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, partner site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany., Leung TF; Department of Paediatrics, The Chinese University of Hong Kong, Hong Kong, China., Wong KC; Department of Chemical Pathology, The Chinese University of Hong Kong, Hong Kong, China., Kan LL; Institute of Chinese Medicine and State Key Laboratory of Research on Bioactivities and Clinical Applications of Medicinal Plants, The Chinese University of Hong Kong, Hong Kong, China., Chong JW; Department of Chemical Pathology, The Chinese University of Hong Kong, Hong Kong, China., Meng QJ; Welcome Centre for Cell Matrix Research, Division of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.; Centre for Biological Timing, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK., Liao J; Department of Chemical Pathology, The Chinese University of Hong Kong, Hong Kong, China., Cheung PF; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, partner site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany.; Spatiotemporal tumor heterogeneity, German Cancer Consortium (DKTK), A Partnership Between German Cancer Research Center (DKFZ) and University Hospital, Essen, Germany., Wong CK; Department of Chemical Pathology, The Chinese University of Hong Kong, Hong Kong, China.; Institute of Chinese Medicine and State Key Laboratory of Research on Bioactivities and Clinical Applications of Medicinal Plants, The Chinese University of Hong Kong, Hong Kong, China.

المصدر: Allergy [Allergy] 2024 May 10. Date of Electronic Publication: 2024 May 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: Denmark NLM ID: 7804028 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1398-9995 (Electronic) Linking ISSN: 01054538 NLM ISO Abbreviation: Allergy Subsets: MEDLINE

المؤلفون: Hamacher R; Department of Medical Oncology, West German Cancer Center, University Hospital Essen, Essen, Germany; rainer.hamacher@uk-essen.de.; German Cancer Consortium, Partner site University Hospital Essen, Essen, Germany., Pabst KM; German Cancer Consortium, Partner site University Hospital Essen, Essen, Germany.; Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, Essen, Germany., Cheung PF; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (Partner Site Essen) and German Cancer Research Center, Heidelberg, Germany., Heilig CE; Department of Translational Medical Oncology, National Center for Tumor Diseases, Heidelberg and German Cancer Research Center, Heidelberg, Germany.; German Cancer Consortium, Core Center Heidelberg, Heidelberg, Germany., Hüllein J; Computational Oncology, Molecular Precision Oncology Program, German Cancer Research Center and National Center for Tumor Diseases, Heidelberg, Germany., Liffers ST; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (Partner Site Essen) and German Cancer Research Center, Heidelberg, Germany., Borchert S; German Cancer Consortium, Partner site University Hospital Essen, Essen, Germany.; Institute of Pathology, West German Cancer Center, University Hospital Essen, Essen, Germany., Costa PF; German Cancer Consortium, Partner site University Hospital Essen, Essen, Germany.; Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, Essen, Germany., Schaarschmidt BM; German Cancer Consortium, Partner site University Hospital Essen, Essen, Germany.; Department of Diagnostic and Interventional Radiology and Neuroradiology, West German Cancer Center, University Hospital Essen, Essen, Germany., Kessler L; German Cancer Consortium, Partner site University Hospital Essen, Essen, Germany.; Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, Essen, Germany., Miera MA; Department of Medical Oncology, West German Cancer Center, University Hospital Essen, Essen, Germany.; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, Essen, Germany., Droste M; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (Partner Site Essen) and German Cancer Research Center, Heidelberg, Germany., Akbulut M; Department of Medical Oncology, West German Cancer Center, University Hospital Essen, Essen, Germany., Falkenhorst J; Department of Medical Oncology, West German Cancer Center, University Hospital Essen, Essen, Germany.; German Cancer Consortium, Partner site University Hospital Essen, Essen, Germany., Zarrad F; German Cancer Consortium, Partner site University Hospital Essen, Essen, Germany.; Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, Essen, Germany., Kostbade K; Department of Medical Oncology, West German Cancer Center, University Hospital Essen, Essen, Germany.; German Cancer Consortium, Partner site University Hospital Essen, Essen, Germany., Mavroeidi IA; Department of Medical Oncology, West German Cancer Center, University Hospital Essen, Essen, Germany.; German Cancer Consortium, Partner site University Hospital Essen, Essen, Germany., Glimm H; Department for Translational Medical Oncology, National Center for Tumor Diseases (NCT/UCC), Dresden, Germany.; German Cancer Research Center, Heidelberg, Germany.; Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany.; Translational Medical Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; German Cancer Consortium, Dresden, Germany; and., Umutlu L; German Cancer Consortium, Partner site University Hospital Essen, Essen, Germany.; Department of Diagnostic and Interventional Radiology and Neuroradiology, West German Cancer Center, University Hospital Essen, Essen, Germany., Schuler M; Department of Medical Oncology, West German Cancer Center, University Hospital Essen, Essen, Germany.; German Cancer Consortium, Partner site University Hospital Essen, Essen, Germany., Hübschmann D; German Cancer Consortium, Core Center Heidelberg, Heidelberg, Germany.; Computational Oncology, Molecular Precision Oncology Program, German Cancer Research Center and National Center for Tumor Diseases, Heidelberg, Germany.; Heidelberg Institute for Stem Cell Technology and Experimental Medicine, Heidelberg, Germany., Bauer S; Department of Medical Oncology, West German Cancer Center, University Hospital Essen, Essen, Germany.; German Cancer Consortium, Partner site University Hospital Essen, Essen, Germany., Fröhling S; Department of Translational Medical Oncology, National Center for Tumor Diseases, Heidelberg and German Cancer Research Center, Heidelberg, Germany.; German Cancer Consortium, Core Center Heidelberg, Heidelberg, Germany., Herrmann K; German Cancer Consortium, Partner site University Hospital Essen, Essen, Germany.; Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, Essen, Germany., Siveke JT; Department of Medical Oncology, West German Cancer Center, University Hospital Essen, Essen, Germany.; German Cancer Consortium, Partner site University Hospital Essen, Essen, Germany.; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (Partner Site Essen) and German Cancer Research Center, Heidelberg, Germany., Schildhaus HU; German Cancer Consortium, Partner site University Hospital Essen, Essen, Germany.; Institute of Pathology, West German Cancer Center, University Hospital Essen, Essen, Germany., Fendler WP; German Cancer Consortium, Partner site University Hospital Essen, Essen, Germany.; Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, Essen, Germany.

المصدر: Journal of nuclear medicine : official publication, Society of Nuclear Medicine [J Nucl Med] 2024 Feb 01; Vol. 65 (2), pp. 252-257. Date of Electronic Publication: 2024 Feb 01.

نوع المنشور: Observational Study; Journal Article

بيانات الدورية: Publisher: Society of Nuclear Medicine Country of Publication: United States NLM ID: 0217410 Publication Model: Electronic Cited Medium: Internet ISSN: 1535-5667 (Electronic) Linking ISSN: 01615505 NLM ISO Abbreviation: J Nucl Med Subsets: MEDLINE

مواضيع طبية MeSH: Solitary Fibrous Tumors* , Quinolines* , Membrane Proteins* , Endopeptidases*, Humans ; Fluorodeoxyglucose F18 ; Gallium Radioisotopes ; Positron-Emission Tomography ; RNA, Messenger ; Positron Emission Tomography Computed Tomography

المؤلفون: Hamacher R; Department of Medical Oncology, West German Cancer Center, University Hospital Essen, Hufelandstr. 55, Essen, 45122 Germany; German Cancer Consortium (DKTK), Partner Site University Hospital Essen, Hufelandstr. 55, Essen, 45122 Germany. Electronic address: rainer.hamacher@uk-essen.de., Lanzafame H; German Cancer Consortium (DKTK), Partner Site University Hospital Essen, Hufelandstr. 55, Essen, 45122 Germany; Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, Hufelandstr. 55, Essen, 45122 Germany., Mavroeidi IA; Department of Medical Oncology, West German Cancer Center, University Hospital Essen, Hufelandstr. 55, Essen, 45122 Germany; German Cancer Consortium (DKTK), Partner Site University Hospital Essen, Hufelandstr. 55, Essen, 45122 Germany., Pabst KM; German Cancer Consortium (DKTK), Partner Site University Hospital Essen, Hufelandstr. 55, Essen, 45122 Germany; Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, Hufelandstr. 55, Essen, 45122 Germany., Kessler L; German Cancer Consortium (DKTK), Partner Site University Hospital Essen, Hufelandstr. 55, Essen, 45122 Germany; Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, Hufelandstr. 55, Essen, 45122 Germany., Cheung PF; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, Hufelandstr. 55, Essen, 45122 Germany; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, Partner Site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany., Bauer S; Department of Medical Oncology, West German Cancer Center, University Hospital Essen, Hufelandstr. 55, Essen, 45122 Germany; German Cancer Consortium (DKTK), Partner Site University Hospital Essen, Hufelandstr. 55, Essen, 45122 Germany., Herrmann K; German Cancer Consortium (DKTK), Partner Site University Hospital Essen, Hufelandstr. 55, Essen, 45122 Germany; Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, Hufelandstr. 55, Essen, 45122 Germany., Schildhaus HU; German Cancer Consortium (DKTK), Partner Site University Hospital Essen, Hufelandstr. 55, Essen, 45122 Germany; Institute of Pathology, West German Cancer Center, University Hospital Essen, Hufelandstr. 55, Essen, 45122 Germany., Siveke JT; Department of Medical Oncology, West German Cancer Center, University Hospital Essen, Hufelandstr. 55, Essen, 45122 Germany; German Cancer Consortium (DKTK), Partner Site University Hospital Essen, Hufelandstr. 55, Essen, 45122 Germany; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, Hufelandstr. 55, Essen, 45122 Germany; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, Partner Site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany., Fendler WP; German Cancer Consortium (DKTK), Partner Site University Hospital Essen, Hufelandstr. 55, Essen, 45122 Germany; Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, Hufelandstr. 55, Essen, 45122 Germany.

المصدر: PET clinics [PET Clin] 2023 Jul; Vol. 18 (3), pp. 361-367. Date of Electronic Publication: 2023 Mar 28.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Saunders Country of Publication: United States NLM ID: 101260152 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-9809 (Electronic) Linking ISSN: 15568598 NLM ISO Abbreviation: PET Clin Subsets: MEDLINE

مواضيع طبية MeSH: Precision Medicine* , Sarcoma*/diagnostic imaging , Sarcoma*/radiotherapy, Humans ; Retrospective Studies ; Medical Oncology ; Fibroblasts ; Positron Emission Tomography Computed Tomography ; Gallium Radioisotopes

المؤلفون: Smeets EMM; Department of Medical Imaging, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands., Dorst DN; Department of Experimental Rheumatology, Radboud Institute for Molecular Life Sciences, 6525 GA Nijmegen, The Netherlands., Franssen GM; Department of Medical Imaging, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands., van Essen MS; Department of Medical Imaging, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands., Frielink C; Department of Medical Imaging, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands., Stommel MWJ; Department of Surgery, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands., Trajkovic-Arsic M; Bridge Institute of Experimental Tumour Therapy, West German Cancer Centre, University Hospital Essen, University of Duisburg-Essen, 47057 Essen, Germany.; Division of Solid Tumour Translational Oncology, German Cancer Consortium (DKTK Partner Site Essen) and German Cancer Research Centre, DKFZ, 69120 Heidelberg, Germany., Cheung PF; Bridge Institute of Experimental Tumour Therapy, West German Cancer Centre, University Hospital Essen, University of Duisburg-Essen, 47057 Essen, Germany.; Division of Solid Tumour Translational Oncology, German Cancer Consortium (DKTK Partner Site Essen) and German Cancer Research Centre, DKFZ, 69120 Heidelberg, Germany., Siveke JT; Bridge Institute of Experimental Tumour Therapy, West German Cancer Centre, University Hospital Essen, University of Duisburg-Essen, 47057 Essen, Germany.; Division of Solid Tumour Translational Oncology, German Cancer Consortium (DKTK Partner Site Essen) and German Cancer Research Centre, DKFZ, 69120 Heidelberg, Germany., Wilson I; ImaginAb, Inglewood, CA 90301, USA., Mascioni A; ImaginAb, Inglewood, CA 90301, USA., Aarntzen EHJG; Department of Medical Imaging, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands., van Lith SAM; Department of Medical Imaging, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.

المصدر: Cells [Cells] 2023 May 18; Vol. 12 (10). Date of Electronic Publication: 2023 May 18.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

مواضيع طبية MeSH: Cancer-Associated Fibroblasts*/metabolism , Pancreatic Neoplasms*/pathology , Photochemotherapy*, Animals ; Mice ; Serine Endopeptidases/metabolism ; Tissue Distribution ; Membrane Proteins/metabolism ; Fibroblasts/metabolism ; Pentetic Acid/metabolism

المؤلفون: Cheung PF; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, partner site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany., Yang J; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, partner site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany., Fang R; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, partner site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany., Borgers A; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, partner site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany., Krengel K; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, partner site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany., Stoffel A; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, partner site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany., Althoff K; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, partner site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany., Yip CW; Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China.; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Siu EHL; Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China., Ng LWC; Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China., Lang KS; Institute of Immunology, Medical Faculty, University of Duisburg-Essen, Essen, Germany., Cham LB; Institute of Immunology, Medical Faculty, University of Duisburg-Essen, Essen, Germany., Engel DR; Department of Immunodynamics, Institute of Experimental Immunology and Imaging, University Hospital Essen, Essen, Germany., Soun C; Department of Immunodynamics, Institute of Experimental Immunology and Imaging, University Hospital Essen, Essen, Germany., Cima I; DKFZ-Division Translational Neurooncology at the WTZ, German Cancer Consortium (DKTK partner site Essen/Düsseldorf), Essen, Germany., Scheffler B; DKFZ-Division Translational Neurooncology at the WTZ, German Cancer Consortium (DKTK partner site Essen/Düsseldorf), Essen, Germany., Striefler JK; Universitätsmedizin Charité Berlin, CONKO Study Group, Department of Medical Oncology, Haematology and Tumorimmunology, Berlin, Germany., Sinn M; Universitätsmedizin Charité Berlin, CONKO Study Group, Department of Medical Oncology, Haematology and Tumorimmunology, Berlin, Germany., Bahra M; Department of Surgical Oncology and Robotics, Krankenhaus Waldfriede, Berlin, Germany., Pelzer U; Medical Department, Division of Hematology, Oncology and Tumor Immunology, Charité University Hospital, Berlin, Germany., Oettle H; Praxis und Tagesklinik, Dresden, Germany., Markus P; Department of General, Visceral and Trauma Surgery, Elisabeth Hospital Essen, Essen, Germany., Smeets EMM; Department of Medical Imaging, Radboud university medical Center, Nijmegen, The Netherlands., Aarntzen EHJG; Department of Medical Imaging, Radboud university medical Center, Nijmegen, The Netherlands., Savvatakis K; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, partner site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany., Liffers ST; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, partner site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany., Lueong SS; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, partner site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany., Neander C; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, partner site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany., Bazarna A; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, partner site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany., Zhang X; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, partner site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany., Paschen A; Department of Dermatology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Crawford HC; Rogel Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI, USA.; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA., Chan AWH; Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China., Cheung ST; Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China. stcheung@surgery.cuhk.edu.hk.; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China. stcheung@surgery.cuhk.edu.hk., Siveke JT; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, Essen, Germany. j.siveke@dkfz.de.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, partner site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany. j.siveke@dkfz.de.

المصدر: Nature communications [Nat Commun] 2022 Jan 10; Vol. 13 (1), pp. 156. Date of Electronic Publication: 2022 Jan 10.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Adenocarcinoma/*genetics , Carcinoma, Pancreatic Ductal/*genetics , Histocompatibility Antigens Class I/*genetics , Pancreatic Neoplasms/*genetics , Progranulins/*genetics , Tumor Escape/*genetics, Adenocarcinoma/immunology ; Adenocarcinoma/mortality ; Adenocarcinoma/therapy ; Animals ; Antibodies, Neutralizing/pharmacology ; Antigens, Viral/genetics ; Antigens, Viral/immunology ; Autophagy/drug effects ; Autophagy/genetics ; Autophagy/immunology ; CD8-Positive T-Lymphocytes/drug effects ; CD8-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/pathology ; Carcinoma, Pancreatic Ductal/immunology ; Carcinoma, Pancreatic Ductal/mortality ; Carcinoma, Pancreatic Ductal/therapy ; Cell Line, Tumor ; Cell Movement/drug effects ; Cohort Studies ; Cytotoxicity, Immunologic ; Gene Expression ; Glycoproteins/genetics ; Glycoproteins/immunology ; Histocompatibility Antigens Class I/immunology ; Humans ; Lymphocytic choriomeningitis virus/genetics ; Lymphocytic choriomeningitis virus/immunology ; Mice ; Pancreatic Neoplasms/immunology ; Pancreatic Neoplasms/mortality ; Pancreatic Neoplasms/therapy ; Peptide Fragments/genetics ; Peptide Fragments/immunology ; Progranulins/antagonists & inhibitors ; Progranulins/immunology ; Proteolysis ; Survival Analysis ; Tumor Microenvironment/genetics ; Tumor Microenvironment/immunology ; Viral Proteins/genetics ; Viral Proteins/immunology ; Xenograft Model Antitumor Assays

المؤلفون: Rosery V; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.; Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Reis H; Institute of Pathology, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Savvatakis K; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK), Partner site University Hospital Essen, and German Cancer Research Center (DKFZ), Heidelberg, Germany., Kowall B; Center of Clinical Epidemiology, Institute for Medical Informatics, Biometry and Epidemiology, Medical Faculty, University Duisburg-Essen, Essen, Germany., Stuschke M; Department of Radiotherapy, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.; German Cancer Consortium (DKTK), Partner site University Hospital Essen, Essen, Germany., Paul A; German Cancer Consortium (DKTK), Partner site University Hospital Essen, Essen, Germany.; General, Visceral and Transplantation Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Dechêne A; Department of Gastroenterology and Hepatology, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.; Department of Internal Medicine 6, Paracelsus Medical University, Nürnberg, Germany., Yang J; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK), Partner site University Hospital Essen, and German Cancer Research Center (DKFZ), Heidelberg, Germany., Zhao B; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK), Partner site University Hospital Essen, and German Cancer Research Center (DKFZ), Heidelberg, Germany., Borgers A; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK), Partner site University Hospital Essen, and German Cancer Research Center (DKFZ), Heidelberg, Germany., Kasper S; Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.; German Cancer Consortium (DKTK), Partner site University Hospital Essen, Essen, Germany., Schuler M; Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.; German Cancer Consortium (DKTK), Partner site University Hospital Essen, Essen, Germany., Cheung PF; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK), Partner site University Hospital Essen, and German Cancer Research Center (DKFZ), Heidelberg, Germany., Siveke JT; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.; Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK), Partner site University Hospital Essen, and German Cancer Research Center (DKFZ), Heidelberg, Germany.; German Cancer Consortium (DKTK), Partner site University Hospital Essen, Essen, Germany.

المصدر: Endocrine-related cancer [Endocr Relat Cancer] 2021 Sep 02; Vol. 28 (10), pp. 683-693. Date of Electronic Publication: 2021 Sep 02.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BioScientifica Country of Publication: England NLM ID: 9436481 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-6821 (Electronic) Linking ISSN: 13510088 NLM ISO Abbreviation: Endocr Relat Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Intestinal Neoplasms*/pathology , Neuroendocrine Tumors*/pathology , Pancreatic Neoplasms*/pathology , Stomach Neoplasms*/pathology, B7-H1 Antigen/metabolism ; Humans ; Immunity ; Programmed Cell Death 1 Receptor/metabolism ; Retrospective Studies ; Tumor Microenvironment

المؤلفون: Zhang X; Institute for Developmental Cancer Therapeutics, West German Cancer Center, University Medicine Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, partner site University Hospital Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany., Zegar T; Institute for Developmental Cancer Therapeutics, West German Cancer Center, University Medicine Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, partner site University Hospital Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany., Weiser T; Structural Genomics Consortium, Buchmann Institute for Life Sciences, Goethe University Frankfurt, Frankfurt, Germany.; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Frankfurt, Germany.; German Cancer Network (DKTK), Frankfurt, Germany., Hamdan FH; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, Göttingen, Germany.; Gene Regulatory Mechanisms and Molecular Epigenetics Lab, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA., Berger BT; Structural Genomics Consortium, Buchmann Institute for Life Sciences, Goethe University Frankfurt, Frankfurt, Germany.; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Frankfurt, Germany., Lucas R; Structural Genomics Consortium, Buchmann Institute for Life Sciences, Goethe University Frankfurt, Frankfurt, Germany.; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Frankfurt, Germany.; German Cancer Network (DKTK), Frankfurt, Germany., Balourdas DI; Structural Genomics Consortium, Buchmann Institute for Life Sciences, Goethe University Frankfurt, Frankfurt, Germany.; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Frankfurt, Germany., Ladigan S; Department of Molecular Gastrointestinal Oncology, Ruhr-University Bochum, Bochum, Germany.; Department of Internal Medicine, Knappschaftskrankenhaus Bochum, Ruhr-University of Bochum, Bochum, Germany., Cheung PF; Institute for Developmental Cancer Therapeutics, West German Cancer Center, University Medicine Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, partner site University Hospital Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany., Liffers ST; Institute for Developmental Cancer Therapeutics, West German Cancer Center, University Medicine Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, partner site University Hospital Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany., Trajkovic-Arsic M; Institute for Developmental Cancer Therapeutics, West German Cancer Center, University Medicine Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, partner site University Hospital Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany., Scheffler B; DKFZ Division of Translational Neurooncology, West German Cancer Center, DKTK partner site University Hospital Essen, Essen, Germany., Joerger AC; Structural Genomics Consortium, Buchmann Institute for Life Sciences, Goethe University Frankfurt, Frankfurt, Germany.; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Frankfurt, Germany.; German Cancer Network (DKTK), Frankfurt, Germany., Hahn SA; Department of Molecular Gastrointestinal Oncology, Ruhr-University Bochum, Bochum, Germany., Johnsen SA; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, Göttingen, Germany.; Gene Regulatory Mechanisms and Molecular Epigenetics Lab, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA., Knapp S; Structural Genomics Consortium, Buchmann Institute for Life Sciences, Goethe University Frankfurt, Frankfurt, Germany.; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Frankfurt, Germany.; German Cancer Network (DKTK), Frankfurt, Germany., Siveke JT; Institute for Developmental Cancer Therapeutics, West German Cancer Center, University Medicine Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, partner site University Hospital Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany.

المصدر: International journal of cancer [Int J Cancer] 2020 Nov 15; Vol. 147 (10), pp. 2847-2861. Date of Electronic Publication: 2020 Jun 29.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0042124 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0215 (Electronic) Linking ISSN: 00207136 NLM ISO Abbreviation: Int J Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , Azepines/*chemistry , Carcinoma, Pancreatic Ductal/*genetics , Histone Deacetylase Inhibitors/*pharmacology , Pancreatic Neoplasms/*drug therapy , Pancreatic Neoplasms/*genetics , Proto-Oncogene Proteins c-fos/*genetics , Triazoles/*chemistry, Carcinoma, Pancreatic Ductal/drug therapy ; Carcinoma, Pancreatic Ductal/metabolism ; Cell Cycle Proteins/chemistry ; Cell Cycle Proteins/metabolism ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Deoxycytidine/analogs & derivatives ; Deoxycytidine/pharmacology ; Drug Synergism ; Epigenesis, Genetic/drug effects ; Gene Expression Regulation, Neoplastic/drug effects ; Histone Deacetylase 1/antagonists & inhibitors ; Humans ; Pancreatic Neoplasms/metabolism ; Protein Domains/drug effects ; Transcription Factors/chemistry ; Transcription Factors/metabolism ; Gemcitabine