-
1
المؤلفون: Chi B. Vu, Min Ding, Ericka L. Benson, Robert Kleemann, Martine C. Morrison, Rick B. Vega, Diana Y. Lee, Maisy Yeager, Michael R. Jirousek, Andrew J. Nichols, Guosheng Liang, Teake Kooistra, Michael Zimmer, Jill C. Milne, Dominic Picarella, Peter Y. Wielinga, Feng Liu, Jay D. Horton, Pradeep Bista
المصدر: Hepatology Communications
مصطلحات موضوعية: 0301 basic medicine, Apolipoprotein E, medicine.medical_specialty, Hepatology, PCSK9, Original Articles, 030204 cardiovascular system & hematology, Biology, medicine.disease, Lipoprotein particle, Sterol regulatory element-binding protein, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, Endocrinology, chemistry, Internal medicine, medicine, Cholesteryl ester, lipids (amino acids, peptides, and proteins), Original Article, Steatohepatitis, Steatosis, Lipoprotein
-
2
المؤلفون: Andrew J. Nichols, John F. Reilly, Mitchell E. Allen, David Brown, Chi B. Vu, Alexander H. Thomson, Diana Lee, Justin B. Perry, Pradeep Bista
المصدر: Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1859:e48-e49
مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Biochemistry, Bioenergetics, Biophysics, Cell Biology, Peroxide
-
3
المؤلفون: Amal Ting, Abby Sewell, Cecilia Pena-Rasgado, Dominic Picarella, Antonio E. Lacerda, Maisy Yeager, Chi B. Vu, Chandran Sachin, Pallavi Lonkar, Robert J. Bridges, A. Nichols, Curtis Bordwell, Feng Liu, Allison Wensley
المصدر: Journal of medicinal chemistry. 60(1)
مصطلحات موضوعية: 0301 basic medicine, Protein Folding, Cysteamine, Cystic Fibrosis Transmembrane Conductance Regulator, Ivacaftor, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Drug Discovery, medicine, Autophagy, chemistry.chemical_classification, biology, Lumacaftor, Fatty Acids, Fatty acid, Potentiator, Cystic fibrosis transmembrane conductance regulator, 030104 developmental biology, chemistry, Biochemistry, 030220 oncology & carcinogenesis, biology.protein, Molecular Medicine, medicine.drug, Conjugate
-
4
المؤلفون: Jill C. Milne, Angela Tornblom, Jean Bemis, Jeremy S. Disch, George P. Vlasuk, Peter Elliot, Amy V. Lynch, Robert B. Perni, Pui Yee Ng, James L. Ellis, Akanksha Gupta, Christopher Oalmann, Joseph J. Nunes, J. Joshua Smith, Kristina Kriksciukaite, Michael R. Jirousek, Marie Yeager, Vipin Suri, David P. Carney, Meghan Duncan, Jeffrey Song, Siva Lavu, Thomas V. Riera, Chi B. Vu
المصدر: Letters in Drug Design & Discovery. 10:793-797
مصطلحات موضوعية: Chemistry, Activator (genetics), Drug Discovery, Pharmaceutical Science, Molecular Medicine, Computational biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d0097b909e7a83a1c2a6561804d09532
https://doi.org/10.2174/15701808113100990021 -
5
المؤلفون: Andrew J. Nichols, Pallavi Lonkar, Jean Bemis, Michael R. Jirousek, Michael Zimmer, Diana Lee, Jill C. Milne, Adam Shoelson, Amal Ting, Dominic Picarella, Maisy Yeager, Ericka L. Benson, Feng Liu, Smith Jesse J, David Carney, Allison Wensley, Chi B. Vu, Richard Fahrner, P. Bista
المصدر: Journal of medicinal chemistry. 59(3)
مصطلحات موضوعية: 0301 basic medicine, ATP citrate lyase, Administration, Oral, Pharmacology, Niacin, Cell Line, Rats, Sprague-Dawley, 03 medical and health sciences, Hydrolysis, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Dogs, Drug Discovery, Animals, Humans, Tissue Distribution, chemistry.chemical_classification, Dose-Response Relationship, Drug, Molecular Structure, Anti-Inflammatory Agents, Non-Steroidal, Fatty Acids, NF-kappa B, Fatty acid, Hep G2 Cells, Sterol regulatory element-binding protein, Rats, 030104 developmental biology, chemistry, Biochemistry, Liver, Molecular Medicine, Sterol Regulatory Element Binding Protein 1, Sterol regulatory element-binding protein 2, Salicylic Acid, Salicylic acid, Sterol Regulatory Element Binding Protein 2
-
6
المؤلفون: David P. Carney, Amy V. Lynch, Robert B. Perni, Pui Yee Ng, Jeremy S. Disch, Roger Xie, Michael R. Jirousek, Jill C. Milne, J. Joshua Smith, Lei Jin, Andre Iffland, Joseph J. Nunes, Jean Bemis, Siva Lavu, Chi B. Vu
المصدر: Bioorganic & Medicinal Chemistry Letters. 19:2350-2353
مصطلحات موضوعية: endocrine system diseases, Pyridines, medicine.medical_treatment, Clinical Biochemistry, Pharmaceutical Science, Mice, Transgenic, Resveratrol, Biochemistry, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Insulin resistance, Sirtuin 1, Drug Discovery, medicine, Animals, Humans, Sirtuins, Oxazoles, Molecular Biology, chemistry.chemical_classification, Insulin, Organic Chemistry, food and beverages, Bridged Bicyclo Compounds, Heterocyclic, medicine.disease, Small molecule, Rats, Rats, Zucker, Enzyme Activation, Enzyme, chemistry, Molecular Medicine, Protein deacetylase, NAD+ kinase, Histone deacetylase, hormones, hormone substitutes, and hormone antagonists
-
7
المؤلفون: Karl D. Normington, Chi B. Vu, Jill C. Milne, Jeffrey Song, Angela Cote, Michael Hirsch, Nekeya Meade, Meghan Davis, David P. Carney, Michael R. Jirousek, Wendy Choy, Philip D. Lambert, David J. Gagne, Elden Lainez, Robert B. Perni
المصدر: Bioorganic & Medicinal Chemistry Letters. 19:1416-1420
مصطلحات موضوعية: Male, Enterocyte, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, Biochemistry, Microsomal triglyceride transfer protein, Rats, Sprague-Dawley, Mice, chemistry.chemical_compound, Oral administration, Cell Line, Tumor, Drug Discovery, medicine, Animals, Humans, Glucose homeostasis, Benzothiazoles, Obesity, Molecular Biology, biology, Chemistry, Drug discovery, Organic Chemistry, Rats, Bioavailability, Mice, Inbred C57BL, Enterocytes, medicine.anatomical_structure, Benzothiazole, Pharmacodynamics, biology.protein, Molecular Medicine, Carrier Proteins
-
8
المؤلفون: Philip D. Lambert, David J. Gagne, Joseph J. Nunes, Jerrold M. Olefsky, Jean Bemis, Chi B. Vu, Jill C. Milne, Amy V. Lynch, J. Joshua Smith, David P. Carney, Michael R. Jirousek, Robert B. Perni, Pui Yee Ng, Jeremy S. Disch, Simon Schenk, Siva Lavu
المصدر: Journal of Medicinal Chemistry. 52:1275-1283
مصطلحات موضوعية: medicine.drug_class, Stereochemistry, Enzyme Activators, Carboxamide, Chemical synthesis, Diabetes Mellitus, Experimental, Mice, Structure-Activity Relationship, Enzyme activator, chemistry.chemical_compound, Sirtuin 1, Quinoxalines, Amide, Drug Discovery, medicine, Animals, Hypoglycemic Agents, Structure–activity relationship, Thiazole, Bicyclic molecule, Imidazoles, Rats, Rats, Zucker, Thiazoles, Diabetes Mellitus, Type 2, chemistry, Molecular Medicine, NAD+ kinase
-
9
المؤلفون: Wendy Choy, Kristine Israelian, J. Joshua Smith, Simon Schenk, Siva Lavu, David P. Carney, Olivier Boss, Philip D. Lambert, Lei Jin, David J. Gagne, David A. Sinclair, Michael R. Jirousek, Andre Iffland, Amy V. Lynch, Jean Bemis, Roger Xie, Robert B. Perni, Pui Yee Ng, Hongying Yang, Jill C. Milne, Jeremy S. Disch, Chi B. Vu, Peter J. Elliott, Jerrold M. Olefsky, Christoph H. Westphal, Heidi Galonek, Oliver Medvedik, Joseph J. Nunes
المصدر: Nature. 450:712-716
مصطلحات موضوعية: Blood Glucose, Male, medicine.medical_specialty, medicine.medical_treatment, Calorie restriction, Adipose tissue, Resveratrol, Heterocyclic Compounds, 4 or More Rings, Article, Cell Line, Rats, Sprague-Dawley, Mice, chemistry.chemical_compound, SRT1720, Insulin resistance, Sirtuin 1, Catalytic Domain, Internal medicine, Stilbenes, medicine, Animals, Humans, Insulin, Sirtuins, Glucose homeostasis, Caloric Restriction, Multidisciplinary, biology, Acetylation, medicine.disease, Dietary Fats, Mitochondria, Rats, Rats, Zucker, Disease Models, Animal, Drosophila melanogaster, Endocrinology, Diabetes Mellitus, Type 2, chemistry, biology.protein, Allosteric Site, hormones, hormone substitutes, and hormone antagonists
-
10دورية أكاديمية
المؤلفون: Jill C. Milne, Philip D. Lambert, Simon Schenk, David P. Carney, Jesse J. Smith, David J. Gagne, Lei Jin, Olivier Boss, Robert B. Perni, Chi B. Vu, Jean E. Bemis, Roger Xie, Jeremy S. Disc
المصدر: Nature, Nature. 450(7170):712-716