المؤلفون: Fotsing JR; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States., Darmohusodo V; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States., Patron AP; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States., Ching BW; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States., Brady T; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States., Arellano M; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States., Chen Q; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States., Davis TJ; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States., Liu H; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States., Servant G; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States., Zhang L; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States., Williams M; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States., Saganich M; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States., Ditschun T; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States., Tachdjian C; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States., Karanewsky DS; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States.

المصدر: Journal of medicinal chemistry [J Med Chem] 2020 May 14; Vol. 63 (9), pp. 4957-4977. Date of Electronic Publication: 2020 Apr 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Hydantoins/*pharmacology , Pyrazoles/*pharmacology , Receptors, Cell Surface/*antagonists & inhibitors , Receptors, G-Protein-Coupled/*antagonists & inhibitors , Taste/*drug effects, Animals ; Coffee/chemistry ; Drug Discovery ; Drug Stability ; Humans ; Hydantoins/chemical synthesis ; Hydantoins/toxicity ; Molecular Structure ; Pyrazoles/chemical synthesis ; Pyrazoles/toxicity ; Rats ; Structure-Activity Relationship