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المؤلفون: Fan W; Gastroenterology and Hepatology, Stanford University, Stanford, CA, USA.; VA, Palo Alto, CA, USA., Adebowale K; Department of Chemical Engineering, Stanford University, Stanford, CA, USA.; Chemistry, Engineering and Medicine for Human Health (ChEM-H), Stanford University, Stanford, CA, USA., Váncza L; Gastroenterology and Hepatology, Stanford University, Stanford, CA, USA.; VA, Palo Alto, CA, USA., Li Y; Gastroenterology and Hepatology, Stanford University, Stanford, CA, USA.; VA, Palo Alto, CA, USA., Rabbi MF; Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, USA., Kunimoto K; Gastroenterology and Hepatology, Stanford University, Stanford, CA, USA.; VA, Palo Alto, CA, USA., Chen D; Gastroenterology and Hepatology, Stanford University, Stanford, CA, USA.; VA, Palo Alto, CA, USA., Mozes G; Gastroenterology and Hepatology, Stanford University, Stanford, CA, USA.; VA, Palo Alto, CA, USA., Chiu DK; Department of Pathology, Stanford University, Stanford, CA, USA.; Division of Immunology, Stanford University, Stanford, CA, USA., Li Y; Department of Automation, Tsinghua University, Beijing, China., Tao J; Pittsburgh Liver Research Center, University of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, PA, USA., Wei Y; Gastroenterology and Hepatology, Stanford University, Stanford, CA, USA.; VA, Palo Alto, CA, USA., Adeniji N; Gastroenterology and Hepatology, Stanford University, Stanford, CA, USA.; VA, Palo Alto, CA, USA., Brunsing RL; Department of Radiology, Stanford University, Stanford, CA, USA., Dhanasekaran R; Gastroenterology and Hepatology, Stanford University, Stanford, CA, USA.; VA, Palo Alto, CA, USA., Singhi A; Pittsburgh Liver Research Center, University of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, PA, USA., Geller D; Pittsburgh Liver Research Center, University of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, PA, USA., Lo SH; Department of Biochemistry and Molecular Medicine, University of California at Davis, Sacramento, CA, USA., Hodgson L; Department of Molecular Pharmacology, Albert Einstein College of Medicine, New York, NY, USA., Engleman EG; Department of Pathology, Stanford University, Stanford, CA, USA.; Division of Immunology, Stanford University, Stanford, CA, USA., Charville GW; Department of Pathology, Stanford University, Stanford, CA, USA., Charu V; Department of Pathology, Stanford University, Stanford, CA, USA.; Quantitative Sciences Unit, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Monga SP; Pittsburgh Liver Research Center, University of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, PA, USA., Kim T; Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, USA.; Faculty of Science and Technology, Keio University, Yokohama, Japan., Wells RG; Departments of Medicine and Bioengineering, University of Pennsylvania, Philadelphia, PA, USA., Chaudhuri O; Chemistry, Engineering and Medicine for Human Health (ChEM-H), Stanford University, Stanford, CA, USA.; Department of Mechanical Engineering, Stanford University, Stanford, CA, USA., Török NJ; Gastroenterology and Hepatology, Stanford University, Stanford, CA, USA. ntorok@stanford.edu.; VA, Palo Alto, CA, USA. ntorok@stanford.edu.

المصدر: Nature [Nature] 2024 Feb; Vol. 626 (7999), pp. 635-642. Date of Electronic Publication: 2024 Jan 31.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Hepatocellular*/complications , Carcinoma, Hepatocellular*/metabolism , Carcinoma, Hepatocellular*/pathology , Elasticity* , Extracellular Matrix*/metabolism , Liver Neoplasms*/complications , Liver Neoplasms*/metabolism , Liver Neoplasms*/pathology , Disease Progression* , Liver Cirrhosis*/complications , Liver Cirrhosis*/metabolism , Liver Cirrhosis*/pathology, Animals ; Humans ; beta Catenin/metabolism ; Cell Proliferation ; Collagen/chemistry ; Collagen/metabolism ; Computer Simulation ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/metabolism ; Glycation End Products, Advanced/metabolism ; Integrin beta1/metabolism ; Neoplasm Invasiveness ; Viscosity ; YAP-Signaling Proteins/metabolism

المؤلفون: Cheu JW; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.; Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong., Chiu DK; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong., Kwan KK; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.; Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong., Yang C; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong., Yuen VW; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.; Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong., Goh CC; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong., Chui NN; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong., Shen W; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.; Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong., Law CT; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong., Li Q; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong., Zhang MS; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.; Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong., Bao MH; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.; Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong., Wong BP; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong., Chan CY; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.; Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong., Liu CX; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong., Sit GF; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong., Ooi ZY; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong., Deng H; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong., Tse AP; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.; Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong., Ng IO; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong., Wong CC; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.; Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong.; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong.; Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Sun Yat-Sen University, Guangzhou, China 510120.; Shenzhen Hospital, The University of Hong Kong, Shenzhen, China.

المصدر: Science advances [Sci Adv] 2023 May 05; Vol. 9 (18), pp. eade5111. Date of Electronic Publication: 2023 May 05.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

مواضيع طبية MeSH: Liver Neoplasms*/pathology , Carcinoma, Hepatocellular*/genetics , Carcinoma, Hepatocellular*/pathology, Animals ; Mice ; Mice, Knockout ; Hypoxia/metabolism ; Adenosine/metabolism ; Cell Line, Tumor ; Tumor Microenvironment

المؤلفون: Chan CY; Department of Pathology , The University of Hong Kong , Hong Kong SAR , China.; Centre for Oncology and Immunology , Hong Kong Science Park , Hong Kong SAR , China., Yuen VW; Department of Pathology , The University of Hong Kong , Hong Kong SAR , China.; Centre for Oncology and Immunology , Hong Kong Science Park , Hong Kong SAR , China., Chiu DK; Department of Pathology , The University of Hong Kong , Hong Kong SAR , China., Goh CC; Department of Pathology , The University of Hong Kong , Hong Kong SAR , China., Thu KL; The Campbell Family Institute for Breast Cancer Research , Princess Margaret Cancer Centre , Toronto , Ontario , Canada., Cescon DW; The Campbell Family Institute for Breast Cancer Research , Princess Margaret Cancer Centre , Toronto , Ontario , Canada., Soria-Bretones I; The Campbell Family Institute for Breast Cancer Research , Princess Margaret Cancer Centre , Toronto , Ontario , Canada., Law CT; Department of Pathology , The University of Hong Kong , Hong Kong SAR , China., Cheu JW; Department of Pathology , The University of Hong Kong , Hong Kong SAR , China.; Centre for Oncology and Immunology , Hong Kong Science Park , Hong Kong SAR , China., Lee D; Department of Pathology , The University of Hong Kong , Hong Kong SAR , China.; Centre for Oncology and Immunology , Hong Kong Science Park , Hong Kong SAR , China., Tse AP; Department of Pathology , The University of Hong Kong , Hong Kong SAR , China.; Centre for Oncology and Immunology , Hong Kong Science Park , Hong Kong SAR , China., Tan KV; Department of Diagnostic Radiology , The University of Hong Kong , Hong Kong SAR , China., Zhang MS; Department of Pathology , The University of Hong Kong , Hong Kong SAR , China.; Centre for Oncology and Immunology , Hong Kong Science Park , Hong Kong SAR , China., Wong BP; Department of Pathology , The University of Hong Kong , Hong Kong SAR , China., Wong CM; Department of Pathology , The University of Hong Kong , Hong Kong SAR , China.; State Key Laboratory of Liver Research , The University of Hong Kong , Hong Kong SAR , China., Khong PL; Department of Diagnostic Radiology , The University of Hong Kong , Hong Kong SAR , China., Ng IO; Department of Pathology , The University of Hong Kong , Hong Kong SAR , China.; State Key Laboratory of Liver Research , The University of Hong Kong , Hong Kong SAR , China., Bray MR; The Campbell Family Institute for Breast Cancer Research , Princess Margaret Cancer Centre , Toronto , Ontario , Canada., Mak TW; Centre for Oncology and Immunology , Hong Kong Science Park , Hong Kong SAR , China.; The Campbell Family Institute for Breast Cancer Research , Princess Margaret Cancer Centre , Toronto , Ontario , Canada., Yau TC; State Key Laboratory of Liver Research , The University of Hong Kong , Hong Kong SAR , China.; Department of Medicine , The University of Hong Kong , Hong Kong SAR , China., Wong CC; Department of Pathology , The University of Hong Kong , Hong Kong SAR , China.; Centre for Oncology and Immunology , Hong Kong Science Park , Hong Kong SAR , China.; State Key Laboratory of Liver Research , The University of Hong Kong , Hong Kong SAR , China.; Guangdong-Hong Kong Joint Laboratory for RNA Medicine , Sun Yat-Sen University , Guangzhou , China.

المصدر: Hepatology (Baltimore, Md.) [Hepatology] 2023 Mar 01; Vol. 77 (3), pp. 729-744. Date of Electronic Publication: 2023 Feb 17.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 8302946 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-3350 (Electronic) Linking ISSN: 02709139 NLM ISO Abbreviation: Hepatology Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Hepatocellular*/pathology , Liver Neoplasms*/pathology, Animals ; Mice ; Aneuploidy ; Cell Cycle ; Cell Line, Tumor ; Protein Serine-Threonine Kinases/metabolism

المؤلفون: Linde IL; Program in Immunology, Stanford University, Stanford, CA 94305, USA; Department of Pathology, Stanford University, Stanford, CA 94305, USA., Prestwood TR; Department of Pathology, Stanford University, Stanford, CA 94305, USA., Qiu J; Department of Pathology, Stanford University, Stanford, CA 94305, USA., Pilarowski G; Department of Pathology, Stanford University, Stanford, CA 94305, USA., Linde MH; Program in Immunology, Stanford University, Stanford, CA 94305, USA., Zhang X; Department of Pathology, Stanford University, Stanford, CA 94305, USA., Shen L; Department of Pathology, Stanford University, Stanford, CA 94305, USA., Reticker-Flynn NE; Department of Pathology, Stanford University, Stanford, CA 94305, USA., Chiu DK; Department of Pathology, Stanford University, Stanford, CA 94305, USA., Sheu LY; Department of Pathology, Stanford University, Stanford, CA 94305, USA., Van Deursen S; Department of Pathology, Stanford University, Stanford, CA 94305, USA., Tolentino LL; Department of Pathology, Stanford University, Stanford, CA 94305, USA., Song WC; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Engleman EG; Program in Immunology, Stanford University, Stanford, CA 94305, USA; Department of Pathology, Stanford University, Stanford, CA 94305, USA. Electronic address: edengleman@stanford.edu.

المصدر: Cancer cell [Cancer Cell] 2023 Feb 13; Vol. 41 (2), pp. 356-372.e10. Date of Electronic Publication: 2023 Jan 26.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101130617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3686 (Electronic) Linking ISSN: 15356108 NLM ISO Abbreviation: Cancer Cell Subsets: MEDLINE

مواضيع طبية MeSH: Neoplasms*/drug therapy , Neoplasms*/metabolism , Antineoplastic Agents*, Mice ; Animals ; Humans ; Neutrophils ; Leukotriene B4/metabolism ; Leukotriene B4/pharmacology ; Tumor Necrosis Factor-alpha/metabolism

المؤلفون: Yuen VW; Department of Pathology; Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong SAR, China., Chiu DK; Department of Pathology., Law CT; Department of Pathology., Cheu JW; Department of Pathology; Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong SAR, China., Chan CY; Department of Pathology; Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong SAR, China., Wong BP; Department of Pathology; Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong SAR, China., Goh CC; Department of Pathology., Zhang MS; Department of Pathology; Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong SAR, China., Xue HD; Department of Pathology; Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong SAR, China., Tse AP; Department of Pathology; Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong SAR, China., Zhang Y; Department of Pathology; Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong SAR, China., Lau HY; Department of Pathology., Lee D; Department of Pathology; Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong SAR, China., Au-Yeung RKH; Department of Pathology; Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong SAR, China., Wong CM; Department of Pathology; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong., Wong CC; Department of Pathology; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong; Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong SAR, China. Electronic address: carmencl@pathology.hku.hk.

المصدر: Journal of hepatology [J Hepatol] 2023 Feb; Vol. 78 (2), pp. 376-389. Date of Electronic Publication: 2022 Nov 29.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8503886 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0641 (Electronic) Linking ISSN: 01688278 NLM ISO Abbreviation: J Hepatol Subsets: MEDLINE

مواضيع طبية MeSH: Liver Neoplasms*/drug therapy , Liver Neoplasms*/genetics , Liver Neoplasms*/metabolism , Carcinoma, Hepatocellular*/drug therapy , Carcinoma, Hepatocellular*/genetics , Carcinoma, Hepatocellular*/metabolism, Humans ; Mice ; Animals ; Immune Checkpoint Inhibitors/pharmacology ; Immune Checkpoint Inhibitors/therapeutic use ; Sorafenib/pharmacology ; Sorafenib/therapeutic use ; Kelch-Like ECH-Associated Protein 1/genetics ; Gene Editing ; CD8-Positive T-Lymphocytes ; NF-E2-Related Factor 2/genetics ; RNA/metabolism

المؤلفون: Chan CY; Department of Pathology, The University of Hong Kong, Pok Fu Lam, Hong Kong Island, Hong Kong.; Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong., Chiu DK; Department of Pathology, The University of Hong Kong, Pok Fu Lam, Hong Kong Island, Hong Kong., Yuen VW; Department of Pathology, The University of Hong Kong, Pok Fu Lam, Hong Kong Island, Hong Kong.; Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong., Law CT; Department of Pathology, The University of Hong Kong, Pok Fu Lam, Hong Kong Island, Hong Kong., Wong BP; Department of Pathology, The University of Hong Kong, Pok Fu Lam, Hong Kong Island, Hong Kong., Thu KL; The Campbell Family Institute for Breast Cancer Research, Princess Margaret Cancer Centre, Toronto, ON, Canada., Cescon DW; The Campbell Family Institute for Breast Cancer Research, Princess Margaret Cancer Centre, Toronto, ON, Canada., Soria-Bretones I; The Campbell Family Institute for Breast Cancer Research, Princess Margaret Cancer Centre, Toronto, ON, Canada., Cheu JW; Department of Pathology, The University of Hong Kong, Pok Fu Lam, Hong Kong Island, Hong Kong.; Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong., Lee D; Department of Pathology, The University of Hong Kong, Pok Fu Lam, Hong Kong Island, Hong Kong.; Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong., Tse AP; Department of Pathology, The University of Hong Kong, Pok Fu Lam, Hong Kong Island, Hong Kong.; Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong., Zhang MS; Department of Pathology, The University of Hong Kong, Pok Fu Lam, Hong Kong Island, Hong Kong.; Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong., Tan KV; Department of Diagnostic Radiology, The University of Hong Kong, Pok Fu Lam, Hong Kong Island, Hong Kong., Ng IO; Department of Pathology, The University of Hong Kong, Pok Fu Lam, Hong Kong Island, Hong Kong.; State Key Laboratory of Liver Research, The University of Hong Kong, Pok Fu Lam, Hong Kong Island, Hong Kong., Khong PL; Department of Diagnostic Radiology, The University of Hong Kong, Pok Fu Lam, Hong Kong Island, Hong Kong., Yau TC; Department of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong Island, Hong Kong.; State Key Laboratory of Liver Research, The University of Hong Kong, Pok Fu Lam, Hong Kong Island, Hong Kong., Bray MR; The Campbell Family Institute for Breast Cancer Research, Princess Margaret Cancer Centre, Toronto, ON, Canada., Mak TW; The Campbell Family Institute for Breast Cancer Research, Princess Margaret Cancer Centre, Toronto, ON, Canada.; Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong., Wong CC; Department of Pathology, The University of Hong Kong, Pok Fu Lam, Hong Kong Island, Hong Kong.; State Key Laboratory of Liver Research, The University of Hong Kong, Pok Fu Lam, Hong Kong Island, Hong Kong.; Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Aug 09; Vol. 119 (32), pp. e2119514119. Date of Electronic Publication: 2022 Aug 01.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Hepatocellular*/drug therapy , Carcinoma, Hepatocellular*/genetics , Liver Neoplasms*/drug therapy , Liver Neoplasms*/genetics , Protein Kinase Inhibitors*/therapeutic use , Pyrazoles*/therapeutic use , Pyrimidines*/therapeutic use, Animals ; CD4-Positive T-Lymphocytes/metabolism ; CD8-Positive T-Lymphocytes/metabolism ; Cell Cycle Proteins/metabolism ; Cell Line, Tumor ; Cell Proliferation ; Killer Cells, Natural/metabolism ; Mice ; Protein Serine-Threonine Kinases ; Protein-Tyrosine Kinases/metabolism

المؤلفون: Zhang MS; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China., Cui JD; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China., Lee D; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China., Yuen VW; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China., Chiu DK; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China., Goh CC; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China., Cheu JW; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China., Tse AP; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China., Bao MH; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China., Wong BPY; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China., Chen CY; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China., Wong CM; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China., Ng IO; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China., Wong CC; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China. carmencl@pathology.hku.hk.; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China. carmencl@pathology.hku.hk.

المصدر: Nature communications [Nat Commun] 2022 Feb 17; Vol. 13 (1), pp. 954. Date of Electronic Publication: 2022 Feb 17.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Hepatocellular/*immunology , Carrier Proteins/*genetics , Hypoxia-Inducible Factor 1, alpha Subunit/*metabolism , Liver Neoplasms/*immunology , Pinocytosis/*immunology , Tumor Hypoxia/*genetics, Animals ; Carcinoma, Hepatocellular/genetics ; Carcinoma, Hepatocellular/pathology ; Carrier Proteins/metabolism ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic/immunology ; Gene Knockdown Techniques ; Humans ; Hypoxia-Inducible Factor 1, alpha Subunit/antagonists & inhibitors ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Liver Neoplasms/genetics ; Liver Neoplasms/pathology ; Mice ; Mice, Knockout ; Pinocytosis/drug effects ; Pinocytosis/genetics ; Proof of Concept Study ; Tumor Hypoxia/immunology ; Xenograft Model Antitumor Assays

المؤلفون: Chui NN; Department of Pathology, The University of Hong Kong, Hong Kong., Cheu JW; Department of Pathology, The University of Hong Kong, Hong Kong., Yuen VW; Department of Pathology, The University of Hong Kong, Hong Kong., Chiu DK; Department of Pathology, The University of Hong Kong, Hong Kong., Goh CC; Department of Pathology, The University of Hong Kong, Hong Kong., Lee D; Department of Pathology, The University of Hong Kong, Hong Kong., Zhang MS; Department of Pathology, The University of Hong Kong, Hong Kong.; ShenZhen Hospital, The University of Hong Kong, Shenzhen, China., Ng IO; Department of Pathology, The University of Hong Kong, Hong Kong.; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong., Wong CC; Department of Pathology, The University of Hong Kong, Hong Kong.; ShenZhen Hospital, The University of Hong Kong, Shenzhen, China.; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong.

المصدر: Hepatology communications [Hepatol Commun] 2022 Jan; Vol. 6 (1), pp. 178-193. Date of Electronic Publication: 2021 Jul 21.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 101695860 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2471-254X (Electronic) Linking ISSN: 2471254X NLM ISO Abbreviation: Hepatol Commun Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Hepatocellular/*immunology , Cholangiocarcinoma/*immunology , Liver Neoplasms/*immunology , MARVEL Domain-Containing Proteins/*genetics , Programmed Cell Death 1 Receptor/*immunology, Animals ; Carcinoma, Hepatocellular/drug therapy ; Carcinoma, Hepatocellular/metabolism ; Cells, Cultured ; Cholangiocarcinoma/drug therapy ; Cholangiocarcinoma/metabolism ; Hepatocytes ; Humans ; Immune Checkpoint Inhibitors/therapeutic use ; Liver Neoplasms/drug therapy ; Liver Neoplasms/metabolism ; MARVEL Domain-Containing Proteins/antagonists & inhibitors ; Mice, Inbred C57BL ; Programmed Cell Death 1 Receptor/antagonists & inhibitors ; Up-Regulation ; Mice

المؤلفون: Zhang Y; Department of Oncology-Pathology, Bioclinicum, Karolinska Institutet, Stockholm 17164, Sweden., Zhang Y; Department of Oncology-Pathology, Bioclinicum, Karolinska Institutet, Stockholm 17164, Sweden., Kameishi S; Department of Oncology-Pathology, Bioclinicum, Karolinska Institutet, Stockholm 17164, Sweden., Barutello G; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Turin, Turin 10126, Italy., Zheng Y; Department of Oncology-Pathology, Bioclinicum, Karolinska Institutet, Stockholm 17164, Sweden., Tobin NP; Department of Oncology-Pathology, Bioclinicum, Karolinska Institutet, Stockholm 17164, Sweden., Nicosia J; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA., Hennig K; Laboratoire Interdisciplinaire de Physique, Université Joseph Fourier (Grenoble 1), Saint Martin d'Hères Cedex, 38402, France., Chiu DK; Department of Oncology-Pathology, Bioclinicum, Karolinska Institutet, Stockholm 17164, Sweden., Balland M; Laboratoire Interdisciplinaire de Physique, Université Joseph Fourier (Grenoble 1), Saint Martin d'Hères Cedex, 38402, France., Barker TH; Department of Biomedical Engineering, University of Virginia, Charlottesville, VA 22904, USA., Cavallo F; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Turin, Turin 10126, Italy., Holmgren L; Department of Oncology-Pathology, Bioclinicum, Karolinska Institutet, Stockholm 17164, Sweden. Electronic address: lars.holmgren@ki.se.

المصدر: Cell reports [Cell Rep] 2021 Aug 24; Vol. 36 (8), pp. 109616.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Cytoskeleton/*metabolism , Fibronectins/*metabolism , Integrins/*metabolism , Neovascularization, Physiologic/*physiology, Angiomotins/metabolism ; Animals ; Cell Membrane/metabolism ; Cell Movement/physiology ; Endothelium/metabolism ; Mice, Transgenic ; Plasma Substitutes/pharmacology ; Pseudopodia/metabolism