نتائج البحث - "Chloroquine/pharmacology"

1

دورية أكاديمية

Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells.

المصدر: The Journal of clinical investigation. 119(5)

مصطلحات موضوعية: Animals, Antineoplastic Agents: pharmacology, therapeutic use, Autophagy: drug effects, physiology, Benzamides, Calcium: metabolism, Cell Death: drug effects, physiology, Cell Line, Tumor, Chloroquine: pharmacology, therapeutic use, Endoplasmic Reticulum: drug effects, metabolism, Fusion Proteins, bcr-abl: antagonists & inhibitors, genetics, Gene Expression: drug effects, genetics, Humans, Leukemia, Myelogenous, Chronic, BCR-ABL Positive: drug therapy, metabolism, pathology, Macrolides: pharmacology, therapeutic use, Mice, Mice, Inbred C3H, Microtubule-Associated Proteins: metabolism, Neoplastic Stem Cells: cytology, drug effects, metabolism, Piperazines: pharmacology, therapeutic use, Protein Kinase Inhibitors: pharmacology, therapeutic use, Protein-Tyrosine Kinases: antagonists & inhibitors, Pyrimidines: pharmacology, therapeutic use, RNA Interference, Thiazoles: pharmacology, therapeutic use, Transcription Factor CHOP: genetics, Xenograft Model Antitumor Assays

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/1pw7d036

2

Chloroquine-susceptible and -resistant Plasmodium falciparum strains survive high chloroquine concentrations by becoming dormant but are eliminated by prolonged exposure

المؤلفون: Johan Ursing, Rasmus Johns, Berit Aydin-Schmidt, Carla Calçada, Poul-Erik Kofoed, Najia Karim Ghanchi, Maria Isabel Veiga, Lars Rombo

المصدر: Ursing, J, Johns, R, Aydin-Schmidt, B, Calçada, C, Kofoed, P E, Ghanchi, N K, Veiga, M I & Rombo, L 2022, ' Chloroquine-susceptible and-resistant Plasmodium falciparum strains survive high chloroquine concentrations by becoming dormant but are eliminated by prolonged exposure ', The Journal of antimicrobial chemotherapy, vol. 77, no. 4, pp. 1005-1011 . https://doi.org/10.1093/jac/dkac008

مصطلحات موضوعية: Pharmacology, Microbiology (medical), Infectious Medicine, Chloroquine/pharmacology, Malaria, Falciparum/drug therapy, Plasmodium falciparum, Drug Resistance, Chloroquine, Infektionsmedicin, Antimalarials, Infectious Diseases, Humans, Pharmacology (medical), Malaria, Falciparum, Antimalarials/pharmacology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99e3e28ca69bac9a45d17778c3994273
https://findresearcher.sdu.dk:8443/ws/files/201618245/Open_Access_Version.pdf

3

Inhibition of Autophagy Does Not Re-Sensitize Acute Myeloid Leukemia Cells Resistant to Cytarabine

المؤلفون: Edwin Bremer, Nienke Visser, Valerie R. Wiersma, Gerwin Huls, Harm Jan Lourens

المساهمون: Stem Cell Aging Leukemia and Lymphoma (SALL), Guided Treatment in Optimal Selected Cancer Patients (GUTS)

المصدر: International Journal of Molecular Sciences
Volume 22
Issue 5
International Journal of Molecular Sciences, 22(5):2337. MDPI AG
International Journal of Molecular Sciences, Vol 22, Iss 2337, p 2337 (2021)

مصطلحات موضوعية: 0301 basic medicine, Myeloid, Antimetabolites, Drug Resistance, Drug Resistance, Neoplasm/drug effects, lcsh:Chemistry, chloroquine, 0302 clinical medicine, AML, cytarabine, Neoplasm/drug effects, hemic and lymphatic diseases, Autophagy/drug effects, Tumor Cells, Cultured, Cytotoxic T cell, lcsh:QH301-705.5, Spectroscopy, Tumor, Chloroquine/pharmacology, Leukemia, Cultured, Myeloid leukemia, General Medicine, Cytarabine/pharmacology, Computer Science Applications, Tumor Cells, Leukemia, Myeloid, Acute, 030220 oncology & carcinogenesis, autophagy inhibitors, medicine.drug, Programmed cell death, Antimetabolites, Antineoplastic, autophagy, therapy resistance, Leukemia, Myeloid, Acute/drug therapy, Catalysis, Article, Cell Line, Inorganic Chemistry, 03 medical and health sciences, Antimetabolites, Antineoplastic/pharmacology, Cell Line, Tumor, medicine, Humans, Acute/drug therapy, Viability assay, Physical and Theoretical Chemistry, Molecular Biology, Antineoplastic/pharmacology, business.industry, Organic Chemistry, Autophagy, carbohydrates (lipids), 030104 developmental biology, lcsh:Biology (General), lcsh:QD1-999, Cell culture, Drug Resistance, Neoplasm, Cancer cell, Cancer research, Cytarabine, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a50bf3f6211005f78ea9b457a2abd2c
https://hdl.handle.net/11370/d64ada6f-7767-435f-af28-f4c0c8f01723

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4

A novel class of fast-acting antimalarial agents: Substituted 15-membered azalides

المصدر: British journal of pharmacology. 178(2)

مصطلحات موضوعية: 0301 basic medicine, Plasmodium falciparum, Drug resistance, Azalide, Pharmacology, Azithromycin, antimalarial, azalide, in vivo efficacy, macrolide, malaria, mode of action, pharmacokinetics, 03 medical and health sciences, Antimalarials, Mice, 0302 clinical medicine, Dogs, In vivo, Chloroquine, medicine, Animals, Antimalarial Agent, Chloroquine / therapeutic use, Mode of action, Antimalarials* / pharmacology, biology, Chemistry, Chloroquine / pharmacology, biology.organism_classification, Malaria* / drug therapy, Malaria, Rats, 030104 developmental biology, Azithromycin / therapeutic use, Antimalarials* / therapeutic use, 030217 neurology & neurosurgery, Azithromycin / pharmacology, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a230fcc3129988b988dd1906910df64
https://pubmed.ncbi.nlm.nih.gov/33085774

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5

Coupling the Antimalarial Cell Penetrating Peptide TP10 to Classical Antimalarial Drugs Primaquine and Chloroquine Produces Strongly Hemolytic Conjugates

المؤلفون: Jiri Gut, Nuno Vale, Fátima Nogueira, Luísa Aguiar, Philip J. Rosenthal, Paula Gomes, Xavier Fernàndez-Busquets, David Andreu, Elena Lantero, Arnau Biosca

المساهمون: Global Health and Tropical Medicine (GHTM), Instituto de Higiene e Medicina Tropical (IHMT), Vector borne diseases and pathogens (VBD), Instituto de Investigação e Inovação em Saúde

المصدر: Molecules
Volume 24
Issue 24
Recercat. Dipósit de la Recerca de Catalunya
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مصطلحات موضوعية: Plasmodium, Primaquine, Erythrocytes, Pharmaceutical Science, Peptide, Antimalarial, Cell-Penetrating Peptides, red blood cell, 01 natural sciences, Erythrocytes / parasitology, Analytical Chemistry, Chloroquine, Drug Discovery, Recombinant Fusion Proteins / chemistry, Flow cytometry, Antimalarials / chemistry, chemistry.chemical_classification, 0303 health sciences, Microscopy, antimalarial, Recombinant Fusion Proteins / pharmacology, Chemistry, Chloroquine / pharmacology, Primaquine / chemistry, Haemolysis, Hemolysis, Red blood cell, Infectious Diseases, Biochemistry, Chemistry (miscellaneous), microscopy, Molecular Medicine, Erythrocytes / metabolism, Intracellular, medicine.drug, Primaquine / pharmacology, primaquine, Recombinant Fusion Proteins, Plasmodium falciparum, Article, Chloroquine / chemistry, 03 medical and health sciences, Antimalarials, SDG 3 - Good Health and Well-being, erythrocyte fluorescence, medicine, Humans, Physical and Theoretical Chemistry, Aminoquinolines, Antimalarials / pharmacology, 030304 developmental biology, Cell penetrating peptide, 010405 organic chemistry, Cell-Penetrating Peptides/ pharmacology, flow cytometry, Organic Chemistry, Erythrocyte fluorescence, medicine.disease, 0104 chemical sciences, cell penetrating peptide, Cell-penetrating peptide, Cell-Penetrating Peptides / chemistry, Plasmodium falciparum / growth & development, hemolysis, Antimalarials / chemical synthesis

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ae9e043ec8e6faa1d496331b652f11c
https://pubmed.ncbi.nlm.nih.gov/31842498

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6

رسالة جامعية

Pharmacodynamic interactions of quinolines with other antimalarial compounds in vitro

المؤلفون: Mariga, Shelton Tendai

مصطلحات موضوعية: Antimalarials -- pharmacology, Drug interactions, Quinolines -- pharmacology, Amodiaquine -- pharmacology, Artemisinins -- pharmacology, Chloroquine -- pharmacology, Plasmodium falciparum -- drug effects

URL الوصول: http://diss.kib.ki.se/2005/91-7140-279-9/

Degree: Diss. (sammanfattning) Stockholm : Karolinska institutet, 2005

7

Biologically Active Acetylenic Amino Alcohol and N -Hydroxylated 1,2,3,4-Tetrahydro-β-carboline Constituents of the New Zealand Ascidian Pseudodistoma opacum

المؤلفون: Jiayi Wang, Michael J. Page, Siouxsie Wiles, Susanna T. S. Chan, A. Norrie Pearce, James P. Dalton, Alexis Valentin, Richard B. Taylor, Brent R. Copp, Marie-Lise Bourguet-Kondracki

المساهمون: University of Auckland [Auckland], National Institute of Water and Atmospheric Research [Auckland] (NIWA), Pharmacochimie et Biologie pour le Développement (PHARMA-DEV), Institut de Recherche pour le Développement (IRD)-Institut de Chimie de Toulouse (ICT-FR 2599), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Institut de Chimie du CNRS (INC)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Institut de Chimie du CNRS (INC), Molécules de Communication et Adaptation des Micro-organismes (MCAM), Muséum national d'Histoire naturelle (MNHN)-Centre National de la Recherche Scientifique (CNRS), University of Auckland, Institut de Recherche pour le Développement (IRD)-Institut de Chimie de Toulouse (ICT), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)

المصدر: Journal of Natural Products
Journal of Natural Products, American Chemical Society, 2015, 79 (3), pp.607-610. ⟨10.1021/acs.jnatprod.5b00770⟩
Journal of Natural Products, 2015, 79 (3), pp.607-610. ⟨10.1021/acs.jnatprod.5b00770⟩

مصطلحات موضوعية: 0301 basic medicine, Circular dichroism, Metabolite, [SDV]Life Sciences [q-bio], Bacterial / drug effects, Drug Resistance, Pharmaceutical Science, medicine.disease_cause, 01 natural sciences, Staphylococcus aureus / drug effects, Analytical Chemistry, chemistry.chemical_compound, Drug Discovery, Antimalarials / chemistry, biology, Molecular Structure, Escherichia coli / drug effects, Absolute configuration, Biological activity, Chloroquine, Chloroquine / pharmacology, Mycobacterium tuberculosis / drug effects, 3. Good health, Staphylococcus aureus, Alkynes, Molecular Medicine, Urochordata / chemistry, Carbolines / isolation & purification, Carbolines / pharmacology, Stereochemistry, Plasmodium falciparum, Alkynes / chemistry, Microbial Sensitivity Tests, 03 medical and health sciences, Antimalarials, Inhibitory Concentration 50, Drug Resistance, Bacterial, Plasmodium falciparum / drug effects, medicine, Escherichia coli, Antimalarials / isolation & purification, Animals, Urochordata, Antimalarials / pharmacology, IC50, Alkynes / isolation & purification, Pharmacology, 010405 organic chemistry, Organic Chemistry, Carbolines / chemistry, Mycobacterium tuberculosis, biology.organism_classification, 0104 chemical sciences, 030104 developmental biology, Complementary and alternative medicine, chemistry, Alkynes / pharmacology, Carbolines, New Zealand

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c56d014e49dd6ceaddc72db8f700a0d
https://hal-univ-tlse3.archives-ouvertes.fr/hal-03184421

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8

Rapid increase in resistance of Plasmodium falciparum to chloroquine-Fansidar in Uganda and the potential of amodiaquine-Fansidar as a better alternative.

المؤلفون: Sendagire, Hakim, Kaddumukasa, Mark, Ndagire, Dorothy, Aguttu, Clare, Nassejje, Maureen, Pettersson, Madeleine, Swedberg, Gote, Kironde, Fred

المصدر: Acta Trop. 95(3):172-82

وصف الملف: print

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-80334
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=16018959&dopt=Citation

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Efficacy of Three Different Regimens of Primaquine for the Prevention of Relapses of Plasmodium vivax Malaria in the Amazon Basin of Peru

المؤلفون: Paul C. F. Graf, César Cabezas, Sonia Gutierrez, Salomón Durand, Andres G. Lescano, Carlos Reyes Álvarez, Meddly L. Santolalla, Mariela Galvez, Nancy Arróspide, David J. Bacon

المصدر: The American Journal of Tropical Medicine and Hygiene

مصطلحات موضوعية: Male, Primaquine, Plasmodium vivax, Parasitemia, Gastroenterology, law.invention, Randomized controlled trial, law, Chloroquine, Recurrence, Peru, Antimalarials/pharmacology, Child, Chloroquine/pharmacology, Primaquine/pharmacology, biology, Articles, Middle Aged, Editorial, Infectious Diseases, Treatment Outcome, Malaria, Vivax/drug therapy/parasitology, Child, Preschool, Drug Therapy, Combination, Female, purl.org/pe-repo/ocde/ford#3.03.06 [https], Amazon basin, medicine.drug, Adult, medicine.medical_specialty, Adolescent, Drug Administration Schedule, Antimalarials, Virology, Internal medicine, medicine, Malaria, Vivax, Humans, Aged, business.industry, medicine.disease, biology.organism_classification, Surgery, Regimen, Plasmodium vivax/physiology, Parasitology, Plasmodium vivax Malaria, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b9ee33c9f35d56a6e726e016359793f
https://europepmc.org/articles/PMC4080559/

10

Simultaneous assessment of autophagy and apoptosis using multispectral imaging cytometry

المؤلفون: Matthew L. Albert, Claire De La Calle, Milena Hasan, Pierre-Emmanuel Joubert, Helen K. W. Law

المساهمون: Centre d'Immunologie Humaine (CIH), Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Supported by grants from ARC (equipment grant to the Centre d’Immunologie Humaine), the Canceropole, Région Ile de France (C.C.), the EURYI Award from the European Science Foundation and the Young Investigator Award from the European Research Council (M.L.A.)., Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM)

المصدر: Autophagy
Autophagy, 2011, 7 (9), pp.1045-51. ⟨10.4161/auto.7.9.16252⟩
Autophagy, Taylor & Francis, 2011, 7 (9), pp.1045-51. ⟨10.4161/auto.7.9.16252⟩

مصطلحات موضوعية: Time Factors, MESH: Fibroblasts/cytology, new methodology, MESH: Fibroblasts/metabolism, Apoptosis, multispectral imaging cytometry, Mutually exclusive events, MESH: Leukocytes, Mononuclear/drug effects, MESH: Apoptosis/radiation effects, Mice, MESH: Image Cytometry/methods, MESH: Animals, Image Cytometry, 0303 health sciences, MESH: Lysosomes/radiation effects, 030302 biochemistry & molecular biology, Chloroquine, Cell biology, Blot, MESH: Autophagy/radiation effects, [SDV.IMM]Life Sciences [q-bio]/Immunology, influenza, MESH: Lysosomes/drug effects, Microtubule-Associated Proteins, Signal Transduction, MESH: Leukocytes, Mononuclear/metabolism, Programmed cell death, MESH: Apoptosis/drug effects, Ultraviolet Rays, MESH: Leukocytes, Mononuclear/cytology, Multiple stress, Biology, Cellular level, 03 medical and health sciences, MESH: Signal Transduction/drug effects, Autophagy, Animals, Humans, MESH: Fibroblasts/radiation effects, MESH: Mice, Molecular Biology, MESH: Chloroquine/pharmacology, 030304 developmental biology, MESH: Humans, MESH: Signal Transduction/radiation effects, MESH: Autophagy/drug effects, MESH: Leukocytes, Mononuclear/radiation effects, MESH: Time Factors, Cell Biology, Fibroblasts, Embryo, Mammalian, MESH: Lysosomes/metabolism, MESH: Fibroblasts/drug effects, MESH: Microtubule-Associated Proteins/metabolism, Leukocytes, Mononuclear, MESH: Ultraviolet Rays, MESH: Embryo, Mammalian/cytology, Lysosomes, Cytometry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcb5c948bf240d6e2706673baef7cf9d
https://pubmed.ncbi.nlm.nih.gov/21606680

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