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المؤلفون: Xu Feng Zhang, Timothy M. Pawlik, Guillaume Martel, Feng Xue, Sorin Alexandrescu, Bas Groot Koerkamp, Luca Aldrighetti, Shishir K. Maithel, Hugo Marques, Yi Lv, Feng Shen, Jin He, Oliver Soubrane, Carlo Pulitano, Endo Itaru, George A. Poultsides, Todd W. Bauer
المساهمون: Zhang, X. -F., Xue, F., He, J., Alexandrescu, S., Marques, H. P., Aldrighetti, L., Maithel, S. K., Pulitano, C., Bauer, T. W., Shen, F., Poultsides, G. A., Soubrane, O., Martel, G., Koerkamp, B. G., Itaru, E., Lv, Y., Pawlik, T. M., Surgery
المصدر: HPB, 23(9), 1456-1466. John Wiley & Sons Inc.
مصطلحات موضوعية: medicine.medical_specialty, Lymph node metastasis, Stage ii, TNM staging system, Cholangiocarcinoma, Cholangiocarcinoma* / surgery, SDG 3 - Good Health and Well-being, Cholangiocarcinoma* / pathology, medicine, Humans, Stage (cooking), Bile Ducts, Intrahepatic / pathology, Intrahepatic Cholangiocarcinoma, Intrahepatic cholangiocarcinoma, AJCC staging system, Neoplasm Staging, Hepatology, business.industry, Gastroenterology, External validation, Cancer, Bile Duct Neoplasms* / pathology, medicine.disease, HCC CIR, Prognosis, Bile Duct Neoplasms* / surgery, Bile Ducts, Intrahepatic, Bile Duct Neoplasms, Radiology, business
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المؤلفون: Nielsen, Patricia Switten, Georgsen, Jeanette Bæhr, Vinding, Mads Sloth, Østergaard, Lasse Riis, Steiniche, Torben
المصدر: Nielsen, P S, Georgsen, J B, Vinding, M S, Østergaard, L R & Steiniche, T 2022, ' Automated annotation of digital H &E/SOX10 dual stains generates high-performing convolutional neural network for calculating tumor burden in H &E-stained cutaneous melanoma ', 34th European Congress of Pathology, Basel, Switzerland, 03/09/2022-07/09/2022 .
Nielsen, P S, Georgsen, J B, Vinding, M S, Østergaard, L R & Steiniche, T 2022, ' Automated annotation of digital H &E/SOX10 dual stains generates high-performing convolutional neural network for calculating tumour burden in H &E-stained cutaneous melanoma ', Virchows Archiv, vol. 481, no. S1, PS-03-019, pp. S80-S80 . https://doi.org/10.1007/s00428-022-03379-4مصطلحات موضوعية: Carcinoma in Situ/pathology, Lymphatic Metastasis/pathology, Cholangiocarcinoma/pathology, Humans, Bile Ducts, Intrahepatic/pathology, Klatskin Tumor/pathology, Bile Duct Neoplasms/pathology, Tumor Suppressor Protein p53/analysis
URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c4435ddcf13e90d1caeaf178c39ffb80
https://pure.au.dk/portal/da/publications/automated-annotation-of-digital-hesox10-dual-stains-generates-highperforming-convolutional-neural-network-for-calculating-tumor-burden-in-hestained-cutaneous-melanoma(15464730-32cc-46a3-864d-5c0b85dbed81).html -
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المصدر: Journal of Experimental & Clinical Cancer Research. 41(1)
مصطلحات موضوعية: B7-H1 Antigen/metabolism, PROGNOSTIC IMPACT, Cholangiocarcinoma/pathology, MICROENVIRONMENT, CD8-Positive T-Lymphocytes, DENDRITIC CELLS, Tumor-infiltrating lymphocytes (TIL), Cholangiocarcinoma, Tumor Microenvironment, Humans, INTRAHEPATIC CHOLANGIOCARCINOMA, Molecular pathogenesis, Lymphocytes, Tumor-Infiltrating, Bile Duct Neoplasms/pathology, Intrahepatic/metabolism, IMMUNOSUPPRESSION, T-LYMPHOCYTE, Prognosis, CANCER, Oncological prognosis, IMMUNE CELLS, Immunotherapy/methods, Systematic review, Bile Ducts, Immunotherapy, TERTIARY LYMPHOID STRUCTURES, RESPONSES
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المؤلفون: Sciarra, A., Park, Y.N., Sempoux, C.
المصدر: Human pathology, vol. 96, pp. 48-55
مصطلحات موضوعية: parasitic diseases, Biomarkers, Tumor/analysis, Biomarkers, Tumor/genetics, Biopsy, Carcinoma, Hepatocellular/chemistry, Carcinoma, Hepatocellular/genetics, Carcinoma, Hepatocellular/pathology, Carcinoma, Hepatocellular/therapy, Cholangiocarcinoma/chemistry, Cholangiocarcinoma/genetics, Cholangiocarcinoma/pathology, Cholangiocarcinoma/therapy, Humans, Immunohistochemistry, Liver Neoplasms/chemistry, Liver Neoplasms/genetics, Liver Neoplasms/pathology, Liver Neoplasms/therapy, Molecular Diagnostic Techniques, Neoplasms, Complex and Mixed/chemistry, Neoplasms, Complex and Mixed/genetics, Neoplasms, Complex and Mixed/pathology, Neoplasms, Complex and Mixed/therapy, Predictive Value of Tests, Prognosis, Cholangiocarcinoma, Cholangiolocarcinoma, Combined hepatocellular-cholangiocarcinoma, Hepatocellular carcinoma, Primary liver carcinoma
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______1900::f9ab3442d27d11d915d43fe84ce1ef32
https://serval.unil.ch/notice/serval:BIB_610E6C9C19DA -
5Trends in use of lymphadenectomy in surgery with curative intent for intrahepatic cholangiocarcinoma
المؤلفون: Yi Lv, Fabio Bagante, Eliza W. Beal, Matthew J. Weiss, Qinyu Chen, Feng Shen, Luca Aldrighetti, Carlo Pulitano, Alfredo Guglielmi, Timothy M. Pawlik, Endo Itaru, Guillaume Martel, Shishir K. Maithel, George A. Poultsides, Hugo Marques, Todd W. Bauer, Oliver Soubrane, Jeffery Chakedis, B. Groot Koerkamp, Irinel Popescu, X-F Zhang
المساهمون: Surgery, Zhang, Xf, Chakedis, J, Bagante, F, Chen, Q, Beal, Ew, Lv, Y, Weiss, M, Popescu, I, Marques, Hp, Aldrighetti, L, Maithel, Sk, Pulitano, C, Bauer, Tw, Shen, F, Poultsides, Ga, Soubrane, O, Martel, G, Koerkamp, Bg, Guglielmi, A, Itaru, E, Pawlik, Tm
المصدر: British Journal of Surgery, 105(7), 857-866. John Wiley & Sons Ltd.
مصطلحات موضوعية: Male, medicine.medical_specialty, Databases, Factual, medicine.medical_treatment, 030230 surgery, Cholangiocarcinoma, 03 medical and health sciences, 0302 clinical medicine, intrahepatic cholangiocarcinoma, Bile Duct Neoplasms / surgery, Humans, Hepatectomy, Medicine, Bile Duct Neoplasms / classification, Lymph node, Intrahepatic Cholangiocarcinoma, Aged, Neoplasm Staging, business.industry, Incidence (epidemiology), Middle Aged, HCC CIR, Lymph Node Excision / statistics & numerical data, Cholangiocarcinoma / classification, Bile Duct Neoplasms / pathology, Surgery, Dissection, medicine.anatomical_structure, Bile Duct Neoplasms, Cholangiocarcinoma / pathology, lymphadenectomy, Lymphatic Metastasis, 030220 oncology & carcinogenesis, Concomitant, Lymph Node Excision, Female, Lymphadenectomy, Cholangiocarcinoma / surgery, Lymph, business
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المؤلفون: Carlo Pulitano, Matthew J. Weiss, Olivier Soubrane, Timothy M. Pawlik, Katiuscha Merath, B. Groot Koerkamp, Luca Aldrighetti, Malcolm H. Squires, Sorin Alexandrescu, Shishir K. Maithel, Endo Itaru, Todd W. Bauer, George A. Poultsides, Hugo Marques, Alfredo Guglielmi, Feng Shen, Guillaume Martel, Fabio Bagante
المساهمون: Bagante, F, Merath, K, Squires, Mh, Weiss, M, Alexandrescu, S, Marques, Hp, Aldrighetti, L, Maithel, Sk, Pulitano, C, Bauer, Tw, Shen, F, Poultsides, Ga, Soubrane, O, Martel, G, Koerkamp, Bg, Guglielmi, A, Itaru, E, Pawlik, Tm, Surgery
المصدر: Journal of Gastrointestinal Surgery, 22(3), 477-485. Springer New York
مصطلحات موضوعية: Male, Survival, Patient risk, medicine.medical_treatment, Nomogram, Cholangiocarcinoma, 0302 clinical medicine, Bile Duct Neoplasms / mortality, Risk Factors, Recurrence, Bile Duct Neoplasms / surgery, Medicine, Intrahepatic Cholangiocarcinoma, Gastroenterology, Middle Aged, ICC, Surgery, Bile Duct Neoplasms / pathology, Lymphatic Metastasis, 030220 oncology & carcinogenesis, Cohort, Female, 030211 gastroenterology & hepatology, Radiology, medicine.medical_specialty, Nomograms, Risk Assessment, Cholangiocarcinoma / mortality, Disease-Free Survival, Resection, Recurrence risk, 03 medical and health sciences, Cholangiocarcinoma / pathology, Humans, Hepatectomy, Aged, business.industry, Proportional hazards model, Neoplasm Recurrence, Local, HCC CIR, Bile Duct Neoplasms, Cholangiocarcinoma / surgery, Neoplasm Grading, business
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المؤلفون: Irinel Popescu, Alfredo Guglielmi, Xu Feng Zhang, Shishir K. Maithel, Hugo Marques, Fabio Bagante, B. Groot Koerkamp, Matthew J. Weiss, George A. Poultsides, Oliver Soubrane, Eliza W. Beal, Luca Aldrighetti, Todd W. Bauer, Guillaume Martel, Dimitrios Moris, Timothy M. Pawlik, Endo Itaru, Jeffery Chakedis, Carlo Pulitano, Feng Shen
المساهمون: Zhang, Xf, Bagante, F, Chakedis, J, Moris, D, Beal, Ew, Weiss, M, Popescu, I, Marques, Hp, Aldrighetti, L, Maithel, Sk, Pulitano, C, Bauer, Tw, Shen, F, Poultsides, Ga, Soubrane, O, Martel, G, Koerkamp, Bg, Guglielmi, A, Itaru, E, Pawlik, Tm, Surgery
المصدر: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
Journal of Gastrointestinal Surgery, 21(11), 1841-1850. Springer New Yorkمصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Surgical margin, medicine.medical_treatment, Bile Duct Neoplasms/mortality, Cholangiocarcinoma/mortality, Cholangiocarcinoma/pathology, Outcomes, 030230 surgery, Bile Duct Neoplasms/surgery, Gastroenterology, Cholangiocarcinoma, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Bile Ducts, Intrahepatic/surgery, Internal medicine, medicine, Hepatectomy, Intrahepatic cholangiocarcinoma, Major, Minor, Humans, Bile Duct Neoplasms/pathology, Survival analysis, Intrahepatic Cholangiocarcinoma, Aged, Cholangiocarcinoma/surgery, Proportional hazards model, business.industry, Postoperative complication, Perioperative, Middle Aged, HCC CIR, Survival Analysis, Bile Ducts, Intrahepatic, Treatment Outcome, Bile Duct Neoplasms, 030220 oncology & carcinogenesis, Propensity score matching, Surgery, Female, business
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المؤلفون: Stefano La Rosa, Laurence de Leval, Benoit Gilbert, Christophe Caux, Christine Sempoux, Christine Ménétrier-Caux, Nermin Halkic, Amedeo Sciarra, Pedro Romero, Inês Monteiro
المساهمون: Lausanne University Hospital, Centre de Recherche en Cancérologie de Lyon (UNICANCER/CRCL), Centre Léon Bérard [Lyon]-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre Léon Bérard [Lyon], Université de Lausanne = University of Lausanne (UNIL), Manship, Brigitte
المصدر: Cancer immunology, immunotherapy, vol. 68, no. 3, pp. 467-478
Cancer Immunology, Immunotherapy
Cancer Immunology, Immunotherapy, 2019, 68 (3), pp.467-478. ⟨10.1007/s00262-018-2290-1⟩مصطلحات موضوعية: Cancer Research, Carcinoma, Hepatocellular, Epithelial-Mesenchymal Transition, Hepatocellular carcinoma, medicine.medical_treatment, [SDV]Life Sciences [q-bio], Immunology, GPI-Linked Proteins, Immune tolerance, CD73, Cholangiocarcinoma, Ecto-5′-nucleotidase, Immunohistochemistry, Pancreatic carcinoma, 03 medical and health sciences, 0302 clinical medicine, Cancer immunotherapy, medicine, Immunology and Allergy, Humans, Epithelial–mesenchymal transition, Biliary Tract, 5'-Nucleotidase, Pancreas, business.industry, Liver Neoplasms, medicine.disease, Prognosis, 3. Good health, Staining, [SDV] Life Sciences [q-bio], Pancreatic Neoplasms, medicine.anatomical_structure, Oncology, Bile Duct Neoplasms, Liver, Biliary tract, 5'-Nucleotidase/analysis, 5'-Nucleotidase/antagonists & inhibitors, Bile Duct Neoplasms/chemistry, Bile Duct Neoplasms/mortality, Bile Duct Neoplasms/pathology, Biliary Tract/chemistry, Carcinoma, Hepatocellular/chemistry, Carcinoma, Hepatocellular/mortality, Carcinoma, Hepatocellular/pathology, Carcinoma, Pancreatic Ductal/chemistry, Carcinoma, Pancreatic Ductal/mortality, Carcinoma, Pancreatic Ductal/pathology, Cholangiocarcinoma/chemistry, Cholangiocarcinoma/mortality, Cholangiocarcinoma/pathology, GPI-Linked Proteins/analysis, GPI-Linked Proteins/antagonists & inhibitors, Liver/chemistry, Liver Neoplasms/chemistry, Liver Neoplasms/mortality, Liver Neoplasms/pathology, Pancreas/chemistry, Pancreatic Neoplasms/chemistry, Pancreatic Neoplasms/mortality, Pancreatic Neoplasms/pathology, Cancer research, business, 030215 immunology, Carcinoma, Pancreatic Ductal
وصف الملف: application/pdf
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المؤلفون: Kota Sahara, Fabio Bagante, Olivier Soubrane, Matthew J. Weiss, Alfredo Guglielmi, Carlo Pulitano, Hugo Marques, Katiuscha Merath, Timothy M. Pawlik, B. Groot Koerkamp, Itaru Endo, Shishir K. Maithel, Ryusei Matsuyama, Luca Aldrighetti, Sorin Alexandrescu, George A. Poultsides, Todd W. Bauer, Guillaume Martel, Diamantis I. Tsilimigras, Feng Shen
المساهمون: Surgery, Sahara, K., Tsilimigras, D. I., Merath, K., Bagante, F., Guglielmi, A., Aldrighetti, L., Weiss, M., Bauer, T. W., Alexandrescu, S., Poultsides, G. A., Maithel, S. K., Marques, H. P., Martel, G., Pulitano, C., Shen, F., Soubrane, O., Koerkamp, B. G., Matsuyama, R., Endo, I., Pawlik, T. M.
المصدر: Annals of Surgical Oncology, 26(9), 2959-2968. Springer New York
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAPمصطلحات موضوعية: Male, medicine.medical_treatment, Midlle Aged, 030230 surgery, Gastroenterology, Intrahepatic cholangiocarcinoma, lymph node metastasis, Hepatectomy / mortality, Cholangiocarcinoma, 0302 clinical medicine, Carcinoembryonic antigen, Surgical oncology, Interquartile range, Bile Duct Neoplasms / surgery, Intrahepatic Cholangiocarcinoma, Intrahepatic cholangiocarcinoma, Lymph Nodes / pathology, biology, lymph node metastasis, Middle Aged, Prognosis, Survival Rate, medicine.anatomical_structure, Therapeutic Index, Oncology, Cholangiocarcinoma / pathology, 030220 oncology & carcinogenesis, Lymphatic Metastasis, Cohort, Female, medicine.medical_specialty, Bile Duct Neoplasms / secondary, 03 medical and health sciences, Internal medicine, medicine, Hepatectomy, Humans, Survival rate, Aged, Neoplasm Staging, business.industry, Hepatoduodenal ligament, HCC CIR, Lymph Node Excision / mortality, Bile Duct Neoplasms, biology.protein, Lymph Node Excision, Surgery, Lymphadenectomy, Cholangiocarcinoma / surgery, Lymph Nodes, business, Follow-Up Studies
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المؤلفون: Rishabh Chawla, Lisa Hoenicke, Nir Rozenblum, Jule Harbig, Johannes Zuber, Marco Seehawer, Gregory J. Dore, Hien Dang, Pierre-François Roux, Florian Heinzmann, Mihael Vucur, Thomas Longerich, Tom Luedde, Bence Sipos, Oliver Bischof, Tae-Won Kang, Xin Wei Wang, Lucas Robinson, Mathias Heikenwalder, Sabrina Klotz, Mareike Roth, Thorsten Buch, Luana D’Artista, Lars Zender
المساهمون: Universitätsklinikum Tübingen - University Hospital of Tübingen, Eberhard Karls Universität Tübingen = Eberhard Karls University of Tuebingen, Organisation Nucléaire et Oncogenèse / Nuclear Organization and Oncogenesis, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Equipe labellisée Ligue contre le Cancer, National Cancer Institute [Bethesda] (NCI-NIH), National Institutes of Health [Bethesda] (NIH), Universität Zürich [Zürich] = University of Zurich (UZH), Universitätsklinikum RWTH Aachen - University Hospital Aachen [Aachen, Germany] (UKA), RWTH Aachen University, Vienna Biocenter - VBC [Austria], University of Tübingen, Heidelberg University Hospital [Heidelberg], German Cancer Research Center - Deutsches Krebsforschungszentrum [Heidelberg] (DKFZ), German Cancer Consortium [Heidelberg] (DKTK), This work was supported by the ERC Consolidator Grant ‘CholangioConcept’ (to L.Z.), the German Research Foundation (DFG): grants FOR2314, SFB685, SFB/TR209 and the Gottfried Wilhelm Leibniz Program (to L.Z.). Further funding was provided by the German Ministry for Education and Research (BMBF) (e:Med/Multiscale HCC), the German Universities Excellence Initiative (third funding line: ‘future concept’), the German Center for Translational Cancer Research (DKTK), the German-Israeli Cooperation in Cancer Research (DKFZ-MOST) (to L.Z.) and the Intramural Research Program of the Centre for Cancer Research, National Cancer Institute, National Institutes of Health (to X.W.W.). The group of O.B. is supported by grants from ANR-BMFT, Fondation ARC pour la recherche sur le Cancer, INSERM, and the National Cancer Institute of the National Institutes of Health under Award Number R01CA136533. O.B. is a CNRS fellow., We thank E. Rist, P. Schiemann, C. Fellmeth, C.-J. Hsieh, D. Heide and J. Hetzer for technical help or assistance. We thank A. Weber for providing TLR2 and TLR4 knockout mice and W. S. Alexander and The Walter and Eliza Hall Institute of Medical Research for providing Mlklfl/fl mice. The Cas9n–p19Arf sgRNA vector was provided by W. Xue. We thank the c.ATG facility of Tuebingen University and CeGaT Tuebingen for exome sequencing and data analysis., Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Rheinisch-Westfälische Technische Hochschule Aachen University (RWTH), University of Zurich, Zender, Lars
المصدر: Nature
Nature, Nature Publishing Group, 2018, 562 (7725), pp.69-75. ⟨10.1038/s41586-018-0519-y⟩
Nature, 2018, 562 (7725), pp.69-75. ⟨10.1038/s41586-018-0519-y⟩مصطلحات موضوعية: 0301 basic medicine, MESH: Necrosis*/genetics, Cellular differentiation, MESH: Cell Lineage*/genetics, MESH: Carcinoma, Hepatocellular/pathology, MESH: Tumor Microenvironment, 10239 Institute of Laboratory Animal Science, MESH: Animals, Cancer epigenetics, MESH: Apoptosis*/genetics, MESH: Transcription Factors/metabolism, MESH: Proto-Oncogene Proteins c-akt/genetics, Multidisciplinary, MESH: Carcinoma, Hepatocellular/genetics, MESH: Cyclin-Dependent Kinase Inhibitor p16/deficiency, 3. Good health, MESH: Carcinogenesis/genetics, MESH: Cholangiocarcinoma/genetics, MESH: Mosaicism, MESH: T-Box Domain Proteins/genetics, Liver cancer, Cancer microenvironment, MESH: Cell Differentiation, Necroptosis, MESH: Cholangiocarcinoma/pathology, MESH: Liver Neoplasms/pathology, Context (language use), 610 Medicine & health, [SDV.CAN]Life Sciences [q-bio]/Cancer, Biology, MESH: DNA-Binding Proteins/metabolism, Article, 03 medical and health sciences, MESH: DNA Transposable Elements/genetics, MESH: Gene Expression Profiling, MESH: Hepatocytes/metabolism, medicine, MESH: Transcription Factors/genetics, MESH: Mice, MESH: Genes, myc, MESH: Liver Neoplasms/genetics, Tumor microenvironment, 1000 Multidisciplinary, MESH: DNA-Binding Proteins/genetics, MESH: Humans, Epigenome, medicine.disease, MESH: Male, digestive system diseases, MESH: Genes, ras, 030104 developmental biology, MESH: Hepatocytes/pathology, Cancer research, Hepatic stellate cell, 570 Life sciences, biology, MESH: Epigenesis, Genetic/genetics, MESH: Cytokines/metabolism, MESH: Disease Models, Animal, MESH: Female, MESH: T-Box Domain Proteins/metabolism
وصف الملف: Seehawer_2018_NATURE_Necroptosis_liver.pdf - application/pdf
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