نتائج البحث - "Chris Yun"

المصدر: Nature medicine 29(6), 1437-1447 (2023). doi:10.1038/s41591-023-02326-3
Mummery, C J, Börjesson-Hanson, A, Blackburn, D J, Vijverberg, E G B, de Deyn, P P, Ducharme, S, Jonsson, M, Schneider, A, Rinne, J O, Ludolph, A C, Bodenschatz, R, Kordasiewicz, H, Swayze, E E, Fitzsimmons, B, Mignon, L, Moore, K M, Yun, C, Baumann, T, Li, D, Norris, D A, Crean, R, Graham, D L, Huang, E, Ratti, E, Bennett, C F, Junge, C & Lane, R M 2023, ' Tau-targeting antisense oligonucleotide MAPTRx in mild Alzheimer’s disease : a phase 1b, randomized, placebo-controlled trial ', Nature Medicine, vol. 29, no. 6, pp. 1437-1447 . https://doi.org/10.1038/s41591-023-02326-3
Nature Medicine. Nature Publishing Group
Nature Medicine, 29, 1437-1447. Nature Publishing Group

مصطلحات موضوعية: General Medicine, ddc:610, General Biochemistry, Genetics and Molecular Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a4826e86379fe0686cd40f5d60108ba
https://doi.org/10.1038/s41591-023-02326-3

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6

دورية أكاديمية

Compensatory Upregulation of LPA2 and Activation of the PI3K-Akt Pathway Prevent LPA5-Dependent Loss of Intestinal Epithelial Cells in Intestinal Organoids

المؤلفون: Zhongxing Liang, C. Chris Yun

المصدر: Cells, Vol 11, Iss 14, p 2243 (2022)

مصطلحات موضوعية: lysophosphatidic acid, LPA5, intestine, epithelial cells, organoid, Cytology, QH573-671

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2073-4409/11/14/2243; https://doaj.org/toc/2073-4409

URL الوصول: https://doaj.org/article/1851ca7391134b908e0ba94e5ecaca55

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Nedd4-2–dependent Ubiquitination Potentiates the Inhibition of Human NHE3 by Cholera Toxin and Enteropathogenic Escherichia coli

المؤلفون: C. Chris Yun, Yiran Han, Songbai Lin, Peijian He, Kayte A. Jenkin

المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 3, Pp 695-716 (2022)
Cellular and Molecular Gastroenterology and Hepatology

مصطلحات موضوعية: NEDD4, RC799-869, CTX, cholera toxin, medicine.disease_cause, IEC, intestinal epithelial cell, Enteropathogenic Escherichia coli, Mice, EPEC, enteropathogenic E coli, PCR, polymerase chain reaction, Ubiquitin, Phosphorylation, Ub, ubiquitin, ANOVA, analysis of variance, Original Research, biology, Sodium-Hydrogen Exchanger 3, Chemistry, FSK, forskolin, Cholera toxin, Gastroenterology, Diseases of the digestive system. Gastroenterology, DUB, deubiquitinating enzyme, Ubiquitin ligase, Diarrhea, DRA, down-regulated in adenoma, NHE, Na+/H+ exchanger, Sodium Transporter, hNHE3, human NHE3, sh, short hairpin, medicine.symptom, Cholera Toxin, macromolecular substances, PKC, protein kinase C, medicine, Animals, Humans, CFTR, cystic fibrosis transmembrane conductance regulator, IF, immunofluorescence, Protein kinase A, HBSS, Hank’s balanced saline solution, Hepatology, Sodium, Ubiquitination, Wild type, ENaC, epithelial Na+ channel, WT, wild-type, Molecular biology, pHi, intracellular pH, biology.protein, Nedd4, neural precursor cell expressed, developmentally down-regulated 4, USP, ubiquitin-specific peptidase, PKA, protein kinase A, SD, standard deviation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01d39e72e4258b61df22d22d51d780ec
https://doi.org/10.1016/j.jcmgh.2021.11.006

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8

Control of Intestinal Epithelial Permeability by Lysophosphatidic Acid Receptor 5

المؤلفون: Mo Wang, C. Chris Yun, Yiran Han, Lei Dong, Peijian He

المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 1073-1092 (2021)

مصطلحات موضوعية: 0301 basic medicine, Male, Lipopolysaccharide, RC799-869, RT-PCR, reverse transcriptase polymerase chain reaction, IEC, intestinal epithelial cell, Cell membrane, chemistry.chemical_compound, Transactivation, Mice, 0302 clinical medicine, LPA5, FD-4, fluorescein isothiocyanate-labeled 4 kDa dextran, Lysophosphatidic acid, Intestinal Mucosa, Receptors, Lysophosphatidic Acid, Receptor, Original Research, ATX, autotaxin, IBD, inflammatory bowel disease, Dextran Sulfate, Gastroenterology, Diseases of the digestive system. Gastroenterology, GI, gastrointestinal, Colitis, Cell biology, LPA, medicine.anatomical_structure, TJ, tight junction, shRNA, short hairpin RNA, LPS, lipopolysaccharide, 030211 gastroenterology & hepatology, Signal transduction, JAMs, junctional adhesion molecules, Rac1, LPA, lysophosphatidic acid, LPA5, LPA receptor 5, Barrier, PBS, phosphate-buffered saline, RAC1, ROCK, RhoA-associated kinase, Permeability, TER, transepithelial electrical resistance, Cell Line, GEF, guanine nucleotide exchange factor, 03 medical and health sciences, Stat, signal transducers and activators of transcription, DSS, dextran sulfate sodium, medicine, Animals, Humans, IF, immunofluorescence, GPCR, G protein-coupled receptor, Intestinal permeability, Hepatology, Stat3, NHE3, Na+/H+ exchanger 3, medicine.disease, AJ, adherens junction, EGFR, epidermal growth factor receptor, Disease Models, Animal, 030104 developmental biology, chemistry, Caco-2 Cells, Lysophospholipids, SD, standard deviation