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1دورية أكاديمية
المؤلفون: Jamie D. Patient, Hadi Hajiali, Kate Harris, Bertil Abrahamsson, Christer Tannergren, Lisa J. White, Amir M. Ghaemmaghami, Philip M. Williams, Clive J. Roberts, Felicity R. A. J. Rose
المصدر: Frontiers in Pharmacology, Vol 10 (2019)
مصطلحات موضوعية: Caco-2 cell line, in vitro model, permeability, barrier integrity, electrospun scaffolds, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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المؤلفون: Christer Tannergren, Harshad Jadhav, Emma Eckernäs, Jonas Fagerberg, Patrick Augustijns, Erik Sjögren
المصدر: European Journal of Pharmaceutics and Biopharmaceutics. 186:144-159
مصطلحات موضوعية: Pharmaceutical Science, General Medicine, Biotechnology
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المؤلفون: Emma Eckernäs, Christer Tannergren
المصدر: Molecular Pharmaceutics
مصطلحات موضوعية: Absorption (pharmacology), PBPK, Physiologically based pharmacokinetic modelling, in silico prediction, Colon, Chemistry, Pharmaceutical, Administration, Oral, Biological Availability, Pharmaceutical Science, 02 engineering and technology, Pharmacology, Models, Biological, 030226 pharmacology & pharmacy, Article, Biopharmaceutics, 03 medical and health sciences, Dogs, 0302 clinical medicine, Suspensions, In vivo, Drug Discovery, Low permeability, Animals, Intestinal Mucosa, colon absorption, drug absorption, Chemistry, 021001 nanoscience & nanotechnology, Bioavailability, Solutions, PBBM, Intestinal Absorption, Solubility, Area Under Curve, Delayed-Action Preparations, Models, Animal, physiologically based biopharmaceutics modeling, Molecular Medicine, Drug product, 0210 nano-technology, Regional differences
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المؤلفون: Erik Sjögren, James Butler, Vidula Kolhatkar, Xavier Pepin, Lynne S. Taylor, Andrew Babiskin, Sandra Suarez-Sharp, Paul Seo, Jennifer B. Dressman, Christer Tannergren, André Dallmann, Xinyuan Zhang, Poonam Delvadia, Edmund Kostewicz, Yang Zhao, Amitava Mitra, Filippos Kesisoglou, Mirko Koziolek, Neil Parrott
المصدر: Journal of Pharmaceutical Sciences. 110:567-583
مصطلحات موضوعية: Research Report, Physiologically based pharmacokinetic modelling, Process management, Computer science, Best practice, media_common.quotation_subject, Administration, Oral, Pharmaceutical Science, 02 engineering and technology, Models, Biological, 030226 pharmacology & pharmacy, Session (web analytics), Biopharmaceutics, 03 medical and health sciences, 0302 clinical medicine, IVIVC, Drug Development, Quality (business), media_common, 021001 nanoscience & nanotechnology, Biopharmaceutical, Model parameter, Intestinal Absorption, Solubility, 0210 nano-technology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4d0f759414a16121ec56c04e1405fb4
https://doi.org/10.1016/j.xphs.2020.09.021 -
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المؤلفون: Alex Mattinson, David Lindley, Helena Engman, Manthena V.S. Varma, Anh-Thu Nguyen-Trung, Binfeng Xia, Xavier Pepin, Linette Ruston, Wei Zhu, Bill van Osdol, Celine Ollier, David Good, Jonathan Brown, Laurent Boulu, Talia Flanagan, Olivier Nicolas, Staffan Berg, Shanoo Budhdeo, Aarti Patel, Jan Bevernage, Handan He, Sweta Modi, Richard Barker, Claire Jackson, Christer Tannergren, Xiojun Ren, Stephane Beilles, J. Matthew Wood, Johanna Laru, Pierre Daublain, Sara Carlert, Louis Henrion, Jean-Flaubert Nguefack, Gunilla Hanisch, Eva Karlsson, Wen Lin, Shruthi Vaidhyanathan, Robert Carr, Fan Wu, Jin Zhang, Amais Ahmad, James M. Mullin, Sari Pappinen, Andrea Moir, Ke Szeto, Christine Xu, Claire Patterson, David B. Turner, Guillaume Louit, Yuya Wang, Tycho Heimbach, Richard Lloyd, Frans Franek, Masoud Jamei, Christophe Tistaert, Bertil Abrahamsson, Kerstin Julia Schäfer, Leon Aarons, Shriram M. Pathak, Adam S. Darwich, Suet Wong, Dónal Murphy, Amin Rostami-Hodjegan, Timo Korjamo, Helena Thörn, Kartrin Schmid, Michael B. Bolger, Johanna Tuunainen, Mai Anh Nguyen
المصدر: European Journal of Pharmaceutics and Biopharmaceutics. 156:50-63
مصطلحات موضوعية: Data Analysis, Physiologically based pharmacokinetic modelling, Databases, Factual, Administration, Oral, Pharmaceutical Science, 02 engineering and technology, Machine learning, computer.software_genre, Models, Biological, 030226 pharmacology & pharmacy, Biopharmaceutics, Pharmaceutical Sciences, 03 medical and health sciences, 0302 clinical medicine, Software, Pharmacokinetics, Humans, Clinical Trials as Topic, business.industry, Compound specific, General Medicine, Farmaceutiska vetenskaper, 021001 nanoscience & nanotechnology, Bioavailability, Intestinal Absorption, Pharmaceutical Preparations, Drug development, Performance indicator, Artificial intelligence, 0210 nano-technology, business, computer, Forecasting, Biotechnology
وصف الملف: application/pdf
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المؤلفون: David Dahlgren, Markus Sjöblom, Christer Tannergren, Anders Lundqvist, Hans Lennernäs, Karsten Peters, Erik Sjögren, Carl Roos
المصدر: European Journal of Pharmaceutics and Biopharmaceutics. 142:31-37
مصطلحات موضوعية: Male, Cell Membrane Permeability, Membrane permeability, Enalaprilat, Intestinal fluid transport, Pharmaceutical Science, Motility, 02 engineering and technology, Intestinal permeability, Pharmacology, 030226 pharmacology & pharmacy, Permeability, Pharmaceutical Sciences, 03 medical and health sciences, 0302 clinical medicine, In vivo, Parecoxib, medicine, Animals, Drug Dosage Calculations, Intestinal Mucosa, Rats, Wistar, Ion transporter, Chemistry, Intestinal physiology, Biological Transport, General Medicine, Farmaceutiska vetenskaper, 021001 nanoscience & nanotechnology, medicine.disease, Atenolol, Rats, 3. Good health, Perfusion, Jejunum, Intestinal Absorption, Pharmaceutical Preparations, Intestinal perfusion, 0210 nano-technology, Biotechnology, medicine.drug
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المؤلفون: Christer Tannergren, Anders Lundqvist, David Dahlgren, Markus Sjöblom, Hans Lennernäs, Erik Sjögren, Carl Roos
المصدر: European Journal of Pharmaceutics and Biopharmaceutics. 132:19-28
مصطلحات موضوعية: Male, Time Factors, Pharmaceutical Science, 02 engineering and technology, Mecamylamine, Pharmacology, 030226 pharmacology & pharmacy, Intestinal absorption, Excipients, Excretion, 03 medical and health sciences, 0302 clinical medicine, Bolus (medicine), Intestinal mucosa, In vivo, Intestine, Small, medicine, Animals, Intestinal Mucosa, Rats, Wistar, Chitosan, Intestinal permeability, Chemistry, Sodium Dodecyl Sulfate, Biological Transport, General Medicine, 021001 nanoscience & nanotechnology, medicine.disease, Rats, Perfusion, Intestinal Absorption, Pharmaceutical Preparations, 0210 nano-technology, Biotechnology, medicine.drug
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المؤلفون: Richard Lloyd, Leon Aarons, Mark McAllister, Amitava Mitra, Chester Costales, Timo Korjamo, Maria Hammarberg, Helena Thörn, Carole Shardlow, Jussi Malkki, Adam S. Darwich, Tycho Heimbach, Achiel Van Peer, James M. Mullin, Jennifer B. Dressman, Johanna Laru, Dónal Murphy, Handan He, Jian Lin, Irina Mishenzon, Ke X. Szeto, Mei Wong, Peter Langguth, Bertil Abrahamsson, Carolin Hoft, Fan Wu, Mohammed Yasin, Olivier Nicolas, Manthena V.S. Varma, Alison Margolskee, Christer Tannergren, Edmund Kostewicz, Yan Pang, Shriram M. Pathak, Johanna Tuunainen, Constanze Hilgendorf, Sari Pappinen, Viera Lukacova, Charles J. Rotter, Jan Bevernage, Sweta Modi, Sergej Ramusovic, Simone Hansmann, Mai Anh Nguyen, Amin Rostami-Hodjegan, Eva Huehn, Michael B. Bolger, Jonathan Brown, Loic Laplanche, Christine Xu, Eva Karlsson, Sara Carlert, Pernilla Johansson, Florent Mazuir, Jeike Biewenga, Xavier Pepin, Hans Lennernäs, Aleksandra Galetin
المصدر: Margolskee, A, Darwich, A, Aarons, L, Galetin, A, Rostami-Hochaghan, A, Carlert, S, Hammarberg, M, Hilgendorf, C, Johansson, P, Karlsson, E, Murphy, D, Tannergren, C, Thorn, H, Yasin, M, Mazuir, F, Nicolas, O, Ramusovic, S, Xu, C, Pathak, S, Korjamo, T, Laru, J, Malkki, J, Pappinen, S, Tuunainen, J, Dressman, J, Hansmann, S, Kostewicz, E, He, H, Heimbach, T, Wu, F, Hoft, C, Laplanche, L, Pang, Y, Bolger, M B, Huehn, E, Lukacova, V, Mullin, J M, Szeto, K X, Costales, C, Lin, J, McAllister, M, Modi, S, Rotter, C, Varma, M, Wong, M, Mitra, A, Bevernage, J, Biewenga, J, Van Peer, A, Lloyd, R, Shardlow, C, Langguth, P, Mishenzon, I, Nguyen, M A, Brown, J, Lennernas, H & Abrahamsson, B 2016, ' IMI – Oral Biopharmaceutics Tools project – Evaluation of Bottom-up PBPK Prediction Success Part 2: An Introduction to the Simulation Exercise and Overview of Results ', European Journal of Pharmaceutical Sciences . https://doi.org/10.1016/j.ejps.2016.10.036
مصطلحات موضوعية: Physiologically based pharmacokinetic modelling, Chemistry, Biopharmaceutics, Drug Evaluation, Preclinical, Area under the curve, Administration, Oral, Pharmaceutical Science, Models, Biological, 030226 pharmacology & pharmacy, Bioavailability, Clinical study, Toxicology, 03 medical and health sciences, 0302 clinical medicine, Intestinal Absorption, Pharmaceutical Preparations, Pharmacokinetics, Compounding, 030220 oncology & carcinogenesis, Statistics, Humans, Computer Simulation, Immediate release, Forecasting
وصف الملف: application/pdf
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المؤلفون: Franziska Graf, Wolfgang Mück, Dominique Swerts, Kerstin J. Frank, Dorina van der Mey, Joanne Bennett, Marta Venczel, Thomas Müller, Uwe Muenster, Hans Lennernäs, Florent Mazuir, Jan Bevernage, Mei Wong, Mark McAllister, Stéphane Beilles, Loic Laplanche, Alison Margolskee, Stefania Beato, Lieve Adriaenssen, Loeckie de Zwart, Jonas Angstenberger, Xavier Pepin, Anh-Thu Nguyen-Trung, Alexander Marker, Amin Rostami-Hodjegan, P. Zane, Céline Ollier, An Van Den Bergh, Adam S. Darwich, Shriram M. Pathak, Dónal Murphy, Markus Kolhmann, Pankaj Daga, Susanne Greschat-Schade, Michael B. Bolger, Achiel Van Peer, Christer Tannergren, Priscilla Brun, Mohammed Yasin, Bertil Abrahamsson, Sara Carlert, Richard Lloyd, Christophe Tistaert, Leon Aarons, Petra Loos, Xavier Boulenc, Pascale Vicat
المصدر: Margolskee, A, Darwich, A, Pepin, X, Pathak, S M, Bolger et al, M B, Aarons, L, Rostami-Hochaghan, A, Angstenberger, J, Graf, F, Laplanche, L, Muller, T, Carlert, S, Daga, P, Murphy, D, Tannergren, C, Yasin, M, Greschat-Schade, S, Muck, W, Muenster, U, van der Mey, D, Frank, K, Lloyd, R, Adriaenssen, L, Bevernage, J, De Zwart, L, Swerts, D, Tistaert, C, Van Den Bergh, A, Van Peer, A, Beato, S, Nguyen-Trung, A-T, Bennett, J, McAllister, M, Wong, M, Zane, P, Ollier, C, Vicat, P, Kolhmann, M, Marker, A, Brun, P, Mazuir, F, Beilles, S, Venczel, M, Boulenc, X, Loos, P, Lennernas, H & Abrahamsson, B 2016, ' IMI – oral biopharmaceutics tools project – evaluation of bottom-up PBPK prediction success part 1: Characterisation of the OrBiTo database of compounds ', European Journal of Pharmaceutical Sciences . https://doi.org/10.1016/j.ejps.2016.09.027
مصطلحات موضوعية: Physiologically based pharmacokinetic modelling, Databases, Factual, Drug Evaluation, Preclinical, Administration, Oral, Pharmaceutical Science, Pharmacology, computer.software_genre, Models, Biological, 030226 pharmacology & pharmacy, Intestinal absorption, Biopharmaceutics, 03 medical and health sciences, 0302 clinical medicine, Humans, Pharmaceutical sciences, Volume of distribution, Database, Chemistry, Biopharmaceutics Classification System, Bioavailability, Biopharmaceutical, Intestinal Absorption, Pharmaceutical Preparations, 030220 oncology & carcinogenesis, computer, Forecasting
وصف الملف: application/pdf
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المؤلفون: Christer Tannergren, Angela Ku, Britta Polentarutti, Lennart Lindfors, Kalle Sigfridsson, Sara Carlert, Eva Karlsson
المصدر: Journal of Pharmaceutical Sciences. 105:3314-3323
مصطلحات موضوعية: Male, Drug, media_common.quotation_subject, Administration, Oral, Pharmaceutical Science, 02 engineering and technology, 030226 pharmacology & pharmacy, Intestinal absorption, Biopharmaceutics, 03 medical and health sciences, Dogs, 0302 clinical medicine, Pharmacokinetics, In vivo, Animals, Humans, Solubility, Cannabinoid Receptor Antagonists, Dissolution, media_common, Supersaturation, Cross-Over Studies, Chromatography, Dose-Response Relationship, Drug, Chemistry, Hydrogen-Ion Concentration, 021001 nanoscience & nanotechnology, Bioavailability, Intestinal Absorption, Female, Salts, 0210 nano-technology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73fdeafc94671abfdc7ea352eaaf334a
https://doi.org/10.1016/j.xphs.2016.07.016
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