المؤلفون: Sarah M. Rothman, Keith Q. Tanis, Pallavi Gandhi, Vladislav Malkov, Jacob Marcus, Michelle Pearson, Richard Stevens, Jason Gilliland, Christopher Ware, Veeravan Mahadomrongkul, Elaine O’Loughlin, Gonzalo Zeballos, Roger Smith, Bonnie J. Howell, Joel Klappenbach, Matthew Kennedy, Christian Mirescu

المصدر: Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-15 (2018)

مصطلحات موضوعية: Alzheimer’s disease, Transcriptomics, Plaque, Microglia, Neuroinflammation, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s12974-018-1265-7; https://doaj.org/toc/1742-2094

URL الوصول: https://doaj.org/article/8e009419f5ab45f69aae66002d9935b3

المؤلفون: Kelley C. Larson, Frederick Gergits, Daria Tchessalova, Abigail Renoux, Matthew Figley, Richard Fisher, Spyros Papapetropoulos, Christian Mirescu

المصدر: Alzheimer's & Dementia. 18

مصطلحات موضوعية: Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Neurology (clinical), Geriatrics and Gerontology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::13187cc7053988fc0d01509c91104eed
https://doi.org/10.1002/alz.061595

المؤلفون: Adrienne E. D. Stormo, Farbod Shavarebi, Molly FitzGibbon, Elizabeth M. Earley, Hannah Ahrendt, Lotus S. Lum, Erik Verschueren, Danielle L. Swaney, Gaia Skibinski, Abinaya Ravisankar, Jeffrey van Haren, Emily J. Davis, Jeffrey R. Johnson, John Von Dollen, Carson Balen, Jacob Porath, Claudia Crosio, Christian Mirescu, Ciro Iaccarino, William T. Dauer, R. Jeremy Nichols, Torsten Wittmann, Timothy C. Cox, Steve Finkbeiner, Nevan J. Krogan, Scott A. Oakes, Annie Hiniker

المساهمون: Cell biology

المصدر: Journal of Cell Biology, 221(4):e202010065. Rockefeller University Press
The Journal of cell biology, vol 221, iss 4

مصطلحات موضوعية: Ubiquitin-Protein Ligases, Neurodegenerative, Protein Serine-Threonine Kinases, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Medical and Health Sciences, Microtubules, Interactome, Tripartite Motif Proteins, Ubiquitin, 2.1 Biological and endogenous factors, Humans, Aetiology, Phosphorylation, Kinase activity, Cytoskeleton, Parkinson's Disease, biology, Chemistry, Kinase, Neurosciences, Ubiquitination, Parkinson Disease, Cell Biology, Biological Sciences, Subcellular localization, LRRK2, Tripartite motif family, Brain Disorders, nervous system diseases, Ubiquitin ligase, Cell biology, rab GTP-Binding Proteins, Neurological, Mutation, biology.protein, Microtubule-Associated Proteins, Developmental Biology, Transcription Factors

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cd9cb26135056e993b76bc0057039aa
https://doi.org/10.1083/jcb.202010065

المؤلفون: Anna-Mari Karkkainen, Philip Manfre, Elaine O’Loughlin, Juha Kuosmanen, Gonzalo Zeballos Zeballos, Kimmo Lehtimäki, Binod Jacob, Takayuki Tsuchiya, Geoffrey B. Varty, Matthew E. Kennedy, Nicholas T Gatto, Thomas W. Rosahl, Sophia Bardehle, Christian Mirescu, Anjali McCullough

مصطلحات موضوعية: Toxin, Multiple sclerosis, Congenic, Biology, medicine.disease_cause, medicine.disease, Microgliosis, Phenotype, White matter, medicine.anatomical_structure, Inbred strain, In vivo, Immunology, medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::26d07f472de9c117ab0bb2ba15fbe88e
https://doi.org/10.1101/2020.12.17.423334

المؤلفون: Matthew E. Kennedy, Christian Mirescu, Sophia Bardehle, Sonal Singh, Alice Zhang, Belma Dogdas, Ilknur Icke

المصدر: Medical Imaging: Digital Pathology

مصطلحات موضوعية: Innate immune system, Microglia, Confocal, Disease, Biology, medicine.disease, Neuroprotection, law.invention, Immune system, medicine.anatomical_structure, Confocal microscopy, law, medicine, Dementia, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d4278fe493e72f4c22d620797771fa8d
https://doi.org/10.1117/12.2512452

المؤلفون: Pallavi Gandhi, Elaine O’Loughlin, Jacob Marcus, Veeravan Mahadomrongkul, Richard C. Stevens, Jason Da Gilliland, Christopher Ware, Bonnie J. Howell, Keith Q. Tanis, Gonzalo Zeballos Zeballos, Joel A. Klappenbach, Michelle Pearson, Sarah M. Rothman, Christian Mirescu, Matthew E. Kennedy, Roger Smith, Vladislav A. Malkov

المصدر: Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-15 (2018)

مصطلحات موضوعية: 0301 basic medicine, Pathology, Plaque, Amyloid, lcsh:RC346-429, Transcriptome, Amyloid beta-Protein Precursor, Mice, 0302 clinical medicine, Neuroinflammation, Correlation of Data, Plaque, Cerebral Cortex, Microglia, General Neuroscience, Microfilament Proteins, Age Factors, medicine.anatomical_structure, Neurology, Cytokines, Alzheimer’s disease, Genetically modified mouse, medicine.medical_specialty, Immunology, Mice, Transgenic, Laser Capture Microdissection, Neuropathology, Biology, 03 medical and health sciences, Cellular and Molecular Neuroscience, Immune system, Alzheimer Disease, medicine, Extracellular, Animals, Humans, RNA, Messenger, Transcriptomics, Gene, lcsh:Neurology. Diseases of the nervous system, Amyloid beta-Peptides, Research, Calcium-Binding Proteins, Disease Models, Animal, 030104 developmental biology, Gene Expression Regulation, Mutation, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2182d7e5163f1471b595d572292944f4
https://doi.org/10.1186/s12974-018-1265-7

المؤلفون: Joel M. Harris, Xiaoping Zhou, John A. Morrow, Sue-Ing Lin, Marco A. S. Baptista, John M. Sanders, Xiaoping Zhang, Hong Mei, Mark W. Embrey, Sylvie M. Sur, Duane E. DeMong, Ravi P. Nargund, Alan Hruza, Heather E. Tiscia, Matthew J. Fell, Zhizhang Yin, Gautam Agnihotri, Honglu Zhang, Thomas J. Greshock, Jack D. Scott, Yinghui Lin, Zhi-Cai Shi, John A. Mccauley, Sarah W. Li, Ronald K. Chang, Mark T. Bilodeau, Michael W. Miller, Reshma Kuvelkar, Andrew Stamford, Marc Poirier, Hong Liu, Megan K. Macala, Kallol Basu, Li Xiao, Lynn A. Hyde, Jonathan T. Kern, Xing Dai, Christian Mirescu, Paul L. Walsh, Matthew E. Kennedy, John J. Renger, Zhiyong Hu, John Columbus, Robert E. Drolet, Eric M. Parker

المصدر: Journal of medicinal chemistry. 60(7)

مصطلحات موضوعية: 0301 basic medicine, Male, Indazoles, Leucine-rich repeat, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, 03 medical and health sciences, 0302 clinical medicine, Drug Discovery, Animals, Humans, c-Raf, Kinase activity, Enzyme Inhibitors, Rats, Wistar, biology, Cyclin-dependent kinase 4, Kinase, Chemistry, Cyclin-dependent kinase 2, Brain, Parkinson Disease, LRRK2, nervous system diseases, Rats, Molecular Docking Simulation, 030104 developmental biology, Protein kinase domain, Biochemistry, biology.protein, Molecular Medicine, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d2ca3dd5156b7d725b7ec9d610b7b59
https://pubmed.ncbi.nlm.nih.gov/28245354

المؤلفون: Aaron R. Friedman, Anna C. Geraghty, Kereshmeh Taravosh-Lahn, Meng-Ko Tsai, Robert M. Sapolsky, Christian Mirescu, Andrea Nicholas, Theo D. Palmer, Daniela Kaufer, David Covarrubias, Darlene D. Francis, David E Pleasure, Amrita Krishnamurthy, Alana T. Wong, Sundari Chetty, Danna Krupik, Elizabeth D. Kirby, Fuzheng Guo

المصدر: Molecular psychiatry

مصطلحات موضوعية: Male, Restraint, Physical, Population, Hippocampus, Mice, Transgenic, Hippocampal formation, Biology, Article, Nestin, Rats, Sprague-Dawley, 03 medical and health sciences, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Receptors, Glucocorticoid, 0302 clinical medicine, Glucocorticoid receptor, Neural Stem Cells, Corticosterone, Animals, RNA, Messenger, education, Glucocorticoids, Molecular Biology, Cells, Cultured, Cell Proliferation, 030304 developmental biology, Neurons, 0303 health sciences, education.field_of_study, Dentate gyrus, Neurogenesis, Cell Differentiation, Neural stem cell, 3. Good health, Disease Models, Animal, Oligodendroglia, Psychiatry and Mental health, nervous system, chemistry, Neuroscience, Stress, Psychological, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49ffb1d334048973018de90816058476
https://doi.org/10.1038/mp.2013.190

المؤلفون: Michelle D. Smith, Eric M. Parker, Lynn A. Hyde, Kallol Basu, Hong Mei, J. Michael Ellis, Frederique M. Poulet, Matthew E. Kennedy, Michael W. Miller, Xiaoping Zhou, Duane E. DeMong, Boonlert Cheewatrakoolpong, John A. Morrow, Yinghui Lin, Matthew J. Fell, Zhizhang Yin, Jack D. Scott, Carrie G. Markgraf, Christian Mirescu

المصدر: The Journal of pharmacology and experimental therapeutics. 355(3)

مصطلحات موضوعية: Male, Indazoles, Pharmacology, Biology, Protein Serine-Threonine Kinases, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Binding, Competitive, Cell Line, Dephosphorylation, Antiparkinson Agents, Mice, In vivo, Animals, Humans, Kinase activity, Phosphorylation, Receptor, Lung, Protein Kinase Inhibitors, Brain Chemistry, Cerebral Cortex, Behavior, Animal, Dose-Response Relationship, Drug, Kinase, Ligand binding assay, Brain, Parkinson Disease, LRRK2, nervous system diseases, Mice, Inbred C57BL, Pyrimidines, Alveolar Epithelial Cells, Mutation, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2ca92ba39cf6f27ca83cb5f2fa840e4
https://pubmed.ncbi.nlm.nih.gov/26407721

المؤلفون: Jennifer D. Peters, Liron Noiman, Elizabeth Gould, Christian Mirescu

المصدر: Proceedings of the National Academy of Sciences. 103:19170-19175

مصطلحات موضوعية: Male, Aging, medicine.medical_specialty, Hippocampus, Rats, Sprague-Dawley, chemistry.chemical_compound, Corticosterone, Internal medicine, medicine, Animals, Effects of sleep deprivation on cognitive performance, Glucocorticoids, Cell Proliferation, Multidisciplinary, business.industry, Neurogenesis, Biological Sciences, Sleep in non-human animals, Rats, Sleep deprivation, medicine.anatomical_structure, Endocrinology, chemistry, Sleep Deprivation, Neuron, medicine.symptom, business, Glucocorticoid, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd2439059e9d34f783459e620745e362
https://doi.org/10.1073/pnas.0608644103