المؤلفون: Jagan Mohan, Christine Girard Blanc, Satish Moparthi, Charlotte Nugues, Sowmya Rama, Stéphane Vassilopoulos, Thomas Wollert

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2422eaa9fb16f3dad7b65c604e8ac0c8
https://doi.org/10.21203/rs.3.rs-1269772/v1

المؤلفون: Christine Girard-Blanc, Marc Baaden, Christèle Huon, Marc Delarue, Gustavo Moraga-Cid, Stéphane Petres, Samuel Murail, Antoine Taly, Laurie Malherbe, Pierre-Jean Corringer, Ludovic Sauguet

المساهمون: Récepteurs Canaux - Channel Receptors, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Dynamique Structurale des Macromolécules (DSM), Dynamique structurale des Macromolécules / Structural Dynamics of Macromolecules, Production de Protéines Recombinantes et d'Anticorps (Plate-Forme), Institut Pasteur [Paris] (IP), Laboratoire de biochimie théorique [Paris] (LBT (UPR_9080)), Institut de biologie physico-chimique (IBPC (FR_550)), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), We acknowledge financial support from the Fondation de la Recherche Médicale (G.M.-C.), the Direction des Applications de la Recherche et des Relations Industrielles (Institut Pasteur), the Agence Nationale de la Recherche ('Nicochimera'), the 'Initiative d’Excellence' (Grant 'Dynamics of Energy Transducing Membranes: Biogenesis and SupraMolecular Organization,' ANR-11-LABX-0011 to S.M., A.T., and M.B.), and the Fondation Pierre-Gilles de Gennes pour la Recherche (S.M.)., ANR-11-LABX-0011,DYNAMO,Dynamique des membranes transductrices d'énergie : biogénèse et organisation supramoléculaire.(2011), ANR-10-BLAN-1534,Nico_chimera,Caracterisation structurale complete des formes ouverte et fermee d'un canal ionique de la famille des recepteurs cys-loop et mecanisme moleculaire de la transition(2010), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris], Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut de biologie physico-chimique (IBPC (FR_550)), Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris], Université Paris Diderot - Paris 7 (UPD7)-Institut de biologie physico-chimique (IBPC), Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), ANR-11-LABX-0011/11-LABX-0011,DYNAMO,Dynamique des membranes transductrices d'énergie : biogénèse et organisation supramoléculaire.(2011)

المصدر: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2015, 112 (9), pp.2865-70. ⟨10.1073/pnas.1417864112⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2015, 112 (9), pp.2865-70. ⟨10.1073/pnas.1417864112⟩

مصطلحات موضوعية: Multidisciplinary, biology, Allosteric regulation, Mutant, GLIC, Biological Sciences, Crystallography, X-Ray, Transmembrane protein, Protein Structure, Tertiary, Structure-Activity Relationship, Transmembrane domain, Drosophila melanogaster, Receptors, Glycine, Allosteric Regulation, Allosteric enzyme, Biochemistry, biology.protein, Biophysics, Animals, Humans, [CHIM]Chemical Sciences, Glycine receptor, Ion channel

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37064df3db1b8f5da60311c739c3f95f
https://doi.org/10.1073/pnas.1417864112

المؤلفون: David Giganti, Anthony Bouillon, Lina Tawk, Fabienne Robert, Mariano Martinez, Elodie Crublet, Patrick Weber, Christine Girard-Blanc, Stéphane Petres, Ahmed Haouz, Jean-François Hernandez

المصدر: Nature, Nature Communications. 5(1):1-11

الإتاحة: https://ideas.repec.org/a/nat/natcom/v5y2014i1d10.1038_ncomms5833.html

المؤلفون: Louis Renault, Christine Girard-Blanc, Célia Deville, François Bontems, Naïma Nhiri, Stéphane Petres, Carine van Heijenoort, Nadine Assrir, Eric Jacquet

المساهمون: Institut de Chimie des Substances Naturelles (ICSN), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Production de Protéines Recombinantes et d'Anticorps (Plate-Forme), Institut Pasteur [Paris] (IP), Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut de Chimie des Substances Naturelles ( ICSN ), Centre National de la Recherche Scientifique ( CNRS ), Institut Pasteur [Paris], Institut de Biologie Intégrative de la Cellule ( I2BC ), Université Paris-Saclay-Centre National de la Recherche Scientifique ( CNRS ) -Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Sud - Paris 11 ( UP11 )

المصدر: FEBS Letters
FEBS Letters, 2016, 590 (20), pp.3690-3699. ⟨10.1002/1873-3468.12423⟩
FEBS Letters, Wiley, 2016, 590 (20), pp.3690-3699. 〈10.1002/1873-3468.12423〉
FEBS Letters, Wiley, 2016, 590 (20), pp.3690-3699. ⟨10.1002/1873-3468.12423⟩

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, β-thymosin/WH2 domains, Protein Conformation, [SDV]Life Sciences [q-bio], Mutant, Biophysics, macromolecular substances, Biology, Crystallography, X-Ray, Biochemistry, Local structure, 03 medical and health sciences, NMR spectroscopy, Structural Biology, Genetics, Animals, Actin-binding protein, dynamic interaction, Molecular Biology, Actin, [ SDV ] Life Sciences [q-bio], Sequence Homology, Amino Acid, Thymosin, Actin remodeling, Cell Biology, Actin cytoskeleton remodeling, Actins, Cell biology, 030104 developmental biology, Mutation, biology.protein, Rabbits, actin, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf65c6918945399e579982338eacea5d
https://pubmed.ncbi.nlm.nih.gov/27680677

المؤلفون: Christine Girard-Blanc, Steven K. H. Foung, Wenyan Wang, Adam Zuiani, Patrick Lau, Michael S. Diamond, Thomas Krey, Zhen-Yong Keck, Félix A. Rey

المساهمون: Stanford School of Medicine [Stanford], Stanford Medicine, Stanford University-Stanford University, Protéopole, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Washington University School of Medicine in St. Louis, Washington University in Saint Louis (WUSTL), Virologie Structurale - Structural Virology, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Journal of Virology
Journal of Virology, American Society for Microbiology, 2016, 90 (6), pp.3112-3122. ⟨10.1128/JVI.02458-15⟩
Journal of Virology, 2016, 90 (6), pp.3112-3122. ⟨10.1128/JVI.02458-15⟩

مصطلحات موضوعية: MESH: Epitopes, B-Lymphocyte, 0301 basic medicine, [SDV.BIO]Life Sciences [q-bio]/Biotechnology, Hepacivirus, medicine.disease_cause, Epitope, MESH: Antibodies, Monoclonal, MESH: Antibodies, Neutralizing, [SPI]Engineering Sciences [physics], Mice, Viral Envelope Proteins, MESH: Animals, MESH: Hepacivirus, virus diseases, Antibodies, Monoclonal, Primary and secondary antibodies, 3. Good health, Epitopes, B-Lymphocyte, Antibody, Protein Binding, medicine.drug_class, Viral protein, Immunology, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Biology, Monoclonal antibody, Microbiology, 03 medical and health sciences, Antigen, Virology, medicine, MESH: Protein Binding, Animals, MESH: Mice, MESH: Epitope Mapping, 030102 biochemistry & molecular biology, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, Hepatitis C Antibodies, Antibodies, Neutralizing, digestive system diseases, Hypervariable region, MESH: Hepatitis C Antibodies, 030104 developmental biology, Epitope mapping, MESH: Viral Envelope Proteins, Insect Science, biology.protein, Pathogenesis and Immunity, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, Epitope Mapping

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::046817d998aa9b0614de3674d8e7e7f2
https://pubmed.ncbi.nlm.nih.gov/26739044

المؤلفون: James E. Voss, Marie-Christine Vaney, Stéphane Duquerroy, Clemens Vonrhein, Christine Girard-Blanc, Elodie Crublet, Andrew Thompson, Gérard Bricogne, Félix A. Rey

المصدر: Nature, Nature. 468(7324):709-712

الإتاحة: https://ideas.repec.org/a/nat/nature/v468y2010i7324d10.1038_nature09555.html

المؤلفون: Stéphane Duquerroy, Christine Girard-Blanc, William Shepard, Wiyada Wongwiwat, Giovanna Barba-Spaeth, Stéphane Petres, Félix A. Rey, Pablo Guardado-Calvo, Ahmed Haouz, Juthathip Mongkolsapaya, M. Erika Navarro Sanchez, Carlos M. Kikuti, Wanwisa Dejnirattisai, Philippe Dussart, Fernando Arenzana-Seisdedos, Alexander Rouvinski, Marie-Christine Vaney, Philippe Desprès, Gavin R. Screaton

المساهمون: Virologie Structurale - Structural Virology, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud - Paris 11 (UP11), Imperial College London, Protéopole, Synchrotron SOLEIL (SSOLEIL), Centre National de la Recherche Scientifique (CNRS), Interactions Moléculaires Flavivirus-Hôtes, Institut Pasteur [Paris] (IP), Pathogénie Virale - Viral Pathogenesis, Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur de la Guyane, Réseau International des Instituts Pasteur (RIIP), Mahidol University [Bangkok], his work was made possible by a Pediatrics Dengue Vaccine Initiative grant to F.A.R., allowing the set up of a production facility of recombinant DENV sE. The co-crystallization with the bnAbs was done with European Union funding (DenFree consortium) to F.A.R. and G.R.S./J.M. F.A.R. acknowledges support from Insitut Pasteur, from the French Government’s ‘Investissements d’Avenir’ program: Laboratoire d’Excellence ‘Integrative Biology of Emerging Infectious Diseases’ (grant number ANR-10-LABX-62-IBEID) and the CNRS. G.S.R. and J.M. were supported by the Medical Research Council, UK, the Wellcome Trust, UK, the National Institute for Health Research Biomedical Research Centre, Funding Scheme. G.R.S. is a Wellcome Trust Senior investigator. We thank staffs at beam lines PROXIMA-1 and PROXIMA-2 at the SOLEIL synchrotron (St Aubin, France) and ID23-2 and ID29 at the European Synchrotron Radiation Facility (Grenoble, France)., ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), Tortosa, Pablo, Integrative Biology of Emerging Infectious Diseases - - IBEID2010 - ANR-10-LABX-0062 - LABX - VALID, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris], Pathogénie Virale, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Medical Research Council (MRC), Wellcome Trust, Commission of the European Communities, Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur [Paris]

المصدر: Nature
Nature, 2015, 520 (7545), pp.109-113. ⟨10.1038/nature14130⟩
Nature, Nature Publishing Group, 2015, 520 (7545), pp.109-113. ⟨10.1038/nature14130⟩

مصطلحات موضوعية: Serotype, MECHANISM, Models, Molecular, MONOCLONAL-ANTIBODY, FAB FRAGMENTS, Protein Conformation, viruses, DROSOPHILA S2 CELLS, Dengue virus, medicine.disease_cause, Antibodies, Viral, Crystallography, X-Ray, Epitope, Dengue fever, Epitopes, FUSION, Viral Envelope Proteins, Virus maturation, [SDV.MP.VIR] Life Sciences [q-bio]/Microbiology and Parasitology/Virology, 0303 health sciences, Multidisciplinary, REFINEMENT, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], BORNE ENCEPHALITIS-VIRUS, ENVELOPE GLYCOPROTEIN, 3. Good health, Multidisciplinary Sciences, Flavivirus, IMMATURE FLAVIVIRUS PARTICLES, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, Science & Technology - Other Topics, [SDV.IMM]Life Sciences [q-bio]/Immunology, [SDV.IMM] Life Sciences [q-bio]/Immunology, General Science & Technology, [SDV.BBM.BS] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], Molecular Sequence Data, Biology, Cross Reactions, Virus, MATURATION, 03 medical and health sciences, Species Specificity, MD Multidisciplinary, medicine, Humans, Antibody-dependent enhancement, 030304 developmental biology, Science & Technology, 030306 microbiology, Dengue Virus, medicine.disease, biology.organism_classification, Virology, Antibodies, Neutralizing, Solubility, Mutation, Protein Multimerization

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5f06fe9efb369c5ae3956d902a14629
https://hal.science/hal-01148962/document

المؤلفون: Mariano A. Martinez, David Giganti, Lina Tawk, Patrick Weber, Jean-François Hernandez, Christine Girard-Blanc, Odile Mercereau-Puijalon, Pedro M. Alzari, Jean-Christophe Barale, Ahmed Haouz, Stéphane Petres, Fabienne Robert, Anthony Bouillon, Elodie Crublet

المساهمون: Microbiologie structurale - Structural Microbiology (Microb. Struc. (UMR_3528 / U-Pasteur_5)), Institut Pasteur [Paris] (IP)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Immunologie moléculaire des parasites, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Protéopole, Institut des Biomolécules Max Mousseron [Pôle Chimie Balard] (IBMM), Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris]-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Bioinformatique structurale, UMS, Institut de biologie structurale (IBS - UMR 5075), Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes (UGA)-Centre National de la Recherche Scientifique (CNRS), Chemistry, Food Chemsitry, University of Hamburg, Production de Protéines Recombinantes et d'Anticorps (Plate-Forme), Institut Pasteur [Paris], Cristallogenèse et Diffraction des Rayons X (Plate-forme/PF6), Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris], Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM)-Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)

المصدر: Nature Communications
Nature Communications, 2014, 5 (1), ⟨10.1038/ncomms5833⟩
Nature Communications, Nature Publishing Group, 2014, 5 (1), ⟨10.1038/ncomms5833⟩

مصطلحات موضوعية: Plasmodium berghei, Molecular Sequence Data, Plasmodium vivax, Protozoan Proteins, Regulator, General Physics and Astronomy, General Biochemistry, Genetics and Molecular Biology, Subtilase, law.invention, Antimalarials, law, parasitic diseases, Malaria, Vivax, Humans, Parasite hosting, [SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology, Amino Acid Sequence, Molecular Targeted Therapy, Subtilisins, ComputingMilieux_MISCELLANEOUS, Crystallography, Multidisciplinary, biology, General Chemistry, biology.organism_classification, Protein Structure, Tertiary, 3. Good health, Cell biology, Biochemistry, Structural biology, Recombinant DNA, Protein quaternary structure

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab647c25d70610285872f7cb7825a5a3
https://hal.science/hal-02378692

المؤلفون: Félix A. Rey, Thomas Krey, Julia Chamot-Rooke, Christian Malosse, Célia Deville, Christine Girard-Blanc, Pablo Guardado-Calvo, Eric Guittet, François Bontems, Ieva Vasiliauskaite, Scott A. Jeffers, Stéphane Petres, Christina Sizun, Annalisa Meola, Carine van Heijenoort

المساهمون: Virologie Structurale, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Institut de Chimie des Substances Naturelles (ICSN), Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), Production de Protéines Recombinantes et d'Anticorps (Plate-Forme), Institut Pasteur [Paris], Spectrométrie de Masse structurale et protéomique, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris] (IP)

المصدر: Journal of Structural Biology
Journal of Structural Biology, Elsevier, 2014, 188 (1), pp.71-78. ⟨10.1016/j.jsb.2014.08.002⟩
Journal of Structural Biology, 2014, 188 (1), pp.71-78. ⟨10.1016/j.jsb.2014.08.002⟩

مصطلحات موضوعية: NMR structural studies of eukaryotic proteins, Mutant, Sf9, Spodoptera, (15)N-labeling of proteins produced in Sf9 and S2 insect cells, Viral Matrix Proteins, Structural Biology, Sf9 Cells, Animals, Humans, [CHIM]Chemical Sciences, Amino Acids, Actin, chemistry.chemical_classification, Nitrogen Radioisotopes, biology, Schneider 2 cells, [CHIM.ORGA]Chemical Sciences/Organic chemistry, Gene Expression Profiling, Viral glycoprotein domain characterization, Nuclear magnetic resonance spectroscopy, biology.organism_classification, Magnetic Resonance Imaging, Yeast, Amino acid, Non-polymerizable actin mutant, Biochemistry, chemistry, Protein Biosynthesis, Drosophila, Cellular and viral membrane fusion proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61c35b59588d92465841fd7af2ae02cf
https://hal.archives-ouvertes.fr/hal-01077147

المؤلفون: Odile Mercereau-Puijalon, Christine Girard-Blanc, Elodie Crublet, David Giganti, Didier Menard, Christophe Benedet, Michael Nilges, Anthony Bouillon, Jean-Christophe Barale, Olivier Gorgette, Stéphane Petres, Benoit Witkowski, Véronique Stoven

المساهمون: Immunologie moléculaire des parasites, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Bioinformatique structurale - Structural Bioinformatics, Institut Pasteur du Cambodge, Réseau International des Instituts Pasteur (RIIP), Production de Protéines Recombinantes et d'Anticorps (Plate-Forme), Institut Pasteur [Paris] (IP), Cancer et génome: Bioinformatique, biostatistiques et épidémiologie d'un système complexe, Mines Paris - PSL (École nationale supérieure des mines de Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut Curie [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre de Bioinformatique (CBIO), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL), This work was supported in part by the 'Fond De ́die ́: Combattre les Maladies Parasitaires' from Sanofi-Aventis and the French Ministry of Research and a grant from the Institut Carnot-Pasteur Maladies Infectieuses., Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris], MINES ParisTech - École nationale supérieure des mines de Paris

المصدر: Journal of Biological Chemistry
Journal of Biological Chemistry, 2013, 288, pp.18561-73. ⟨10.1074/jbc.M113.456764⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2013, 288, pp.18561-73. ⟨10.1074/jbc.M113.456764⟩

مصطلحات موضوعية: Models, Molecular, MESH: Merozoites, Erythrocytes, Plasmodium berghei, MESH: Sequence Homology, Amino Acid, medicine.medical_treatment, Plasmodium vivax, Protease Inhibitor, MESH: Serine Proteases, Protozoan Proteins, MESH: Amino Acid Sequence, Biochemistry, Substrate Specificity, MESH: Dose-Response Relationship, Drug, Mice, MESH: Protein Structure, Tertiary, Structural Biology, Sf9 Cells, MESH: Sf9 Cells, MESH: Animals, MESH: Protozoan Proteins, 0303 health sciences, Molecular Structure, biology, MESH: Kinetics, MESH: Erythrocytes, Egress, [SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], 3. Good health, MESH: Plasmodium vivax, Female, Serine Proteinase Inhibitors, MESH: Biocatalysis, MESH: Models, Molecular, medicine.drug, MESH: Serine Proteinase Inhibitors, In silico, Molecular Sequence Data, MESH: Malaria, MESH: Molecular Structure, Antimalarials, 03 medical and health sciences, stomatognathic system, parasitic diseases, medicine, Animals, MESH: Plasmodium berghei, Amino Acid Sequence, Drug Target, Molecular Biology, MESH: Mice, 030304 developmental biology, Virtual screening, Binding Sites, Protease, MESH: Molecular Sequence Data, Dose-Response Relationship, Drug, Sequence Homology, Amino Acid, Merozoites, 030306 microbiology, Subtilisin, Computational Biology, Plasmodium falciparum, Cell Biology, biology.organism_classification, MESH: Antimalarials, Protease inhibitor (biology), Protein Structure, Tertiary, Malaria, Kinetics, Virtual Screening, MESH: Binding Sites, Biocatalysis, Parasitology, MESH: Substrate Specificity, Serine Proteases, MESH: Female

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c80039312579028fdd99d5c3a837ec7a
https://hal-pasteur.archives-ouvertes.fr/pasteur-01457905/document