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المؤلفون: R. Ursula Kammlott, Deborah Carol Reuter, Teresa Alejandra Trejo-Martin, Leyi Gong, Christophe Michoud, Andreas Kuglstatter, Patricia Tran, David Michael Goldstein, Yun-Chou Tan, Parcharee Tivitmahaisoon, Linghao Niu, Shao-Yong Wu, Sue Jin, Paul Weller, Gary Hsieh, Karin Ann Stein, Humberto Bartolome Arzeno, James Patrick Dunn, Ada Shao, Wylie Solang Palmer, J. Heather Hogg, Johannes C. Hermann, Kung-ching Chang, Bindu Goyal, Alam Jahangir, Cheryl Janson, Tania Silva, Christine Lukacs, Paul J. Wagner, Muzaffar Alam
المصدر: Bioorganic & Medicinal Chemistry Letters. 23:1486-1492
مصطلحات موضوعية: Models, Molecular, Pyrimidine, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, Crystallography, X-Ray, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Drug Discovery, Animals, Humans, Structure–activity relationship, Protein Kinase Inhibitors, Molecular Biology, Benzotriazole, biology, Kinase, Organic Chemistry, Cyclin-dependent kinase 2, c-jun, JNK Mitogen-Activated Protein Kinases, Triazoles, Rats, Bioavailability, Pyrimidines, chemistry, Drug Design, biology.protein, Molecular Medicine
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المؤلفون: Jin-Jun Liu, Christophe Michoud, Feng Chi, Yang Wen, Qing Xiang, Nam T. Le, Shaoqing Chen, Nicole Jackson, Jian Ping Lou, Li Chen, Chunlin Zhao, Achyutharao Sidduri, Louis Portland, Lyubomir T. Vassilev, Fred Konzelmann, Yingsi Chen, Christian Tovar
المصدر: Bioorganic & Medicinal Chemistry Letters. 17:2134-2138
مصطلحات موضوعية: Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, Biochemistry, Chemical synthesis, Structure-Activity Relationship, Cyclin-dependent kinase, Cell Line, Tumor, CDC2 Protein Kinase, Drug Discovery, Humans, Structure–activity relationship, Protein kinase A, Protein Kinase Inhibitors, Molecular Biology, Cyclin-dependent kinase 1, biology, Chemistry, Kinase, Organic Chemistry, Thiazoles, biology.protein, Molecular Medicine, Drug Screening Assays, Antitumor, Signal transduction
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المؤلفون: Cheryl Janson, Martin Weisel, Barry Goggin, Liang Weiling, Adrian J. Fretland, Robert Francis Kester, Christine Lukacs, Edmund Lee, Jennifer Lo, J. Heather Hogg, Xiaochun Han, Kyoungja Hong, Stacy Remiszewski, Shirley Li, Ann Polonskaia, John Anthony Moliterni, Kang Le, Lin Gao, Nam T. Le, Christophe Michoud, A. Schutt, Shahid Tannu, Andrew F. Donnell, Shaoqing Chen, Louis J. Lombardo, Steven Gregory Mischke, Mark T. Dvorozniak, Yan Lou, Christine Tardell, Kenneth Carey Rupert, Doug Aguilar, Dave S. Solis
المصدر: Journal of medicinal chemistry. 56(20)
مصطلحات موضوعية: Models, Molecular, Cell Survival, Ubiquitin-Protein Ligases, Blotting, Western, Mice, Nude, Apoptosis, X-Linked Inhibitor of Apoptosis Protein, Inhibitor of apoptosis, Crystallography, X-Ray, Inhibitor of Apoptosis Proteins, Mice, Heterocyclic Compounds, Cell Line, Tumor, Drug Discovery, Animals, Humans, Caspase, Caspase-9, Caspase 7, Benzodiazepinones, Alanine, biology, Molecular Structure, Chemistry, Caspase 3, Xenograft Model Antitumor Assays, In vitro, Cell biology, XIAP, Protein Structure, Tertiary, Models, Chemical, Cell culture, Cancer cell, biology.protein, Molecular Medicine, Female
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المؤلفون: Kang Le, Christophe Michoud, Robert T. Taylor, Christine Lukacs, Andrew D. Schutt, Lin Gao, Anthony Specian, Kenneth Carey Rupert, Stacy Remiszewski, Ann Polonskaia, Douglas Aguilar, Barry Goggin, John Anthony Moliterni, J. Heather Hogg, Liang Weiling, Xiaochun Han, Cheryl Janson, Louis J. Lombardo, Martin Weisel, Adrian J. Fretland, Steven Gregory Mischke, Norman Kong, Shirley Li, Robert Francis Kester, Andrew F. Donnell, Kyoungja Hong, Dave S. Solis, Karl Frank, Yan Lou
المصدر: Journal of medicinal chemistry. 56(20)
مصطلحات موضوعية: Models, Molecular, Cell Survival, Ubiquitin-Protein Ligases, Blotting, Western, Regulator, Mice, Nude, Apoptosis, X-Linked Inhibitor of Apoptosis Protein, Inhibitor of apoptosis, Crystallography, X-Ray, Inhibitor of Apoptosis Proteins, Mice, In vivo, Heterocyclic Compounds, Cell Line, Tumor, Drug Discovery, Animals, Humans, Caspase, Caspase 7, Alanine, biology, Molecular Structure, Chemistry, Caspase 3, Antibodies, Monoclonal, Xenograft Model Antitumor Assays, Cell biology, XIAP, Protein Structure, Tertiary, Rats, Oxazepines, Models, Chemical, Cell culture, Cancer cell, biology.protein, Molecular Medicine, Female
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المؤلفون: Robert Crowther, Darin L Steele, Pete William Dunten, Jeffrey A. Engler, Christophe Michoud, J.J. Birktoft, L. Jack Windsor, R. Ursula Kammlott, Ossama El-Kabbani
المصدر: Protein Engineering, Design and Selection. 13:397-405
مصطلحات موضوعية: Models, Molecular, Proteolysis, Bioengineering, Matrix Metalloproteinase Inhibitors, Matrix metalloproteinase, Crystallography, X-Ray, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, medicine, Aminobiphenyl Compounds, Humans, Enzyme Inhibitors, Sodium dodecyl sulfate, Molecular Biology, Polyacrylamide gel electrophoresis, Binding Sites, Tissue Inhibitor of Metalloproteinase-1, biology, medicine.diagnostic_test, Active site, Glutamic acid, Trypsin, Molecular biology, Protein Structure, Tertiary, Enzyme Activation, Glutamine, Amino Acid Substitution, chemistry, Mutagenesis, Site-Directed, biology.protein, Gelatin, Electrophoresis, Polyacrylamide Gel, Matrix Metalloproteinase 3, HeLa Cells, Protein Binding, Biotechnology, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fce5ad94935a6e1f6e46a997f667e002
https://doi.org/10.1093/protein/13.6.397 -
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المؤلفون: Surendra P. Singh, Claire Dufour, Christophe Michoud, Viresh H. Rawal
المصدر: The Journal of Organic Chemistry. 58:7718-7727
مصطلحات موضوعية: chemistry.chemical_compound, Bicyclic molecule, Chemistry, Hydride, Radical, Organic Chemistry, Free-radical reaction, Organic chemistry, Radical initiator, Tributyltin hydride, Alkylation, Selectivity
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المؤلفون: Christophe Michoud, Robert F. Monestel, Viresh H. Rawal
المصدر: ChemInform. 24
مصطلحات موضوعية: biology, Chemistry, Organic chemistry, Dehydrotubifoline, Strychnos, General Medicine, biology.organism_classification
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المؤلفون: Viresh H. Rawal, Christophe Michoud
المصدر: ChemInform. 23
مصطلحات موضوعية: chemistry.chemical_compound, chemistry, biology, Heck reaction, Intramolecular force, Strychnos, General Medicine, Nonane, biology.organism_classification, Medicinal chemistry, Unit (ring theory)
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المؤلفون: Claire Dufour, Surendra P. Singh, Christophe Michoud, Viresh H. Rawal
المصدر: ChemInform. 23
مصطلحات موضوعية: Chemistry, Radical, Organic chemistry, General Medicine
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المؤلفون: Christophe Michoud, Viresh H. Rawal
المصدر: ChemInform. 25
مصطلحات موضوعية: Olefin fiber, Carbamate, Chemistry, Heck reaction, Intramolecular force, medicine.medical_treatment, medicine, chemistry.chemical_element, Chelation, General Medicine, Photochemistry, Medicinal chemistry, Palladium
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