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1دورية أكاديمية
المؤلفون: Tracy-Shi Zhang Fang, Yu Sun, Andrew C. Pearce, Simona Eleuteri, Mark Kemp, Christopher A. Luckhurst, Rachel Williams, Ross Mills, Sarah Almond, Laura Burzynski, Nóra M. Márkus, Christopher J. Lelliott, Natasha A. Karp, David J. Adams, Stephen P. Jackson, Jin-Feng Zhao, Ian G. Ganley, Paul W. Thompson, Gabriel Balmus, David K. Simon
المصدر: Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2041-1723
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2
المؤلفون: Tammy Ladduwahetty, Matthew R. Lee, Michel C. Maillard, Roger Cachope, Daniel Todd, Michael Barnes, Vahri Beaumont, Alka Chauhan, Caroline Gallati, Alan F. Haughan, Georg Kempf, Christopher A. Luckhurst, Kim Matthews, George McAllister, Philip Mitchell, Hiral Patel, Mark Rose, Elizabeth Saville-Stones, Stefan Steinbacher, Andrew J. Stott, Emma Thatcher, Jason Tierney, Liudvikas Urbonas, Ignacio Munoz-Sanjuan, Celia Dominguez
المصدر: Journal of medicinal chemistry. 65(14)
مصطلحات موضوعية: Disease Models, Animal, Huntingtin Protein, Mice, rho-Associated Kinases, Huntington Disease, Drug Discovery, Molecular Medicine, Animals, Brain, Protein Kinase Inhibitors
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3
المؤلفون: James Westcott, Christopher A. Luckhurst, Grahame McKenzie, Danish Memon, Li-Chiung Lin, Sinead Knight, Elizabeth J. Blaikley, Martin Pearce, Hannah R. Warren, Eleanor Parker, Graeme Milligan, Stuart W. Hughes, Tom McCarthy
المصدر: Cancer Research. 83:454-454
مصطلحات موضوعية: Cancer Research, Oncology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9746540fba97b4b14b9644ec6c5f83e9
https://doi.org/10.1158/1538-7445.am2023-454 -
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المؤلفون: Elizabeth Anne Saville-Stones, Alexander H. Borchers, David Allcock, Wesley Blackaby, Gillian Creighton-Gutteridge, Andrew J. Stott, Ignacio Munoz-Sanjuan, Julie Vann, Rebecca E. Jarvis, Dawn Yates, Celia Dominguez, Amanda Van de Poël, Vahri Beaumont, Michel Maillard, Scott Pollack, Rachel Williams, Christopher A. Luckhurst, Huw D. Vater, Omar Aziz, Alan Findlay Haughan, George McAllister, Kim L. Matthews, Perla Breccia
المصدر: ACS Med Chem Lett
مصطلحات موضوعية: Trifluoromethyl, 010405 organic chemistry, Organic Chemistry, Oxadiazole, Computational biology, medicine.disease, 01 natural sciences, Biochemistry, Class (biology), 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry.chemical_compound, Huntington's disease, chemistry, Drug Discovery, medicine
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المؤلفون: Christopher A. Luckhurst, Omar Aziz, Vahri Beaumont, Roland W. Bürli, Perla Breccia, Michel C. Maillard, Alan F. Haughan, Marieke Lamers, Phil Leonard, Kim L. Matthews, Gilles Raphy, Andrew J. Stott, Ignacio Munoz-Sanjuan, Beth Thomas, Michael Wall, Grant Wishart, Dawn Yates, Celia Dominguez
المصدر: Bioorganicmedicinal chemistry letters. 29(1)
مصطلحات موضوعية: Dose-Response Relationship, Drug, Molecular Structure, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Hydroxamic Acids, Biochemistry, Histone Deacetylases, Histone Deacetylase Inhibitors, Mice, Structure-Activity Relationship, Drug Discovery, Molecular Medicine, Animals, Humans, Molecular Biology
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المؤلفون: Elizabeth Kinchin, Lilian Alcaraz, Aaron Rigby, Haydn Beaton, Matt Soars, Rebecca Denton, Keith Bowers, Ash Bahl, David Donald, John Collington, Cathy MacDonald, Rob Riley, Peter J. H. Webborn, Christopher A. Luckhurst, Brian Springthorpe, Mark Furber
المصدر: Bioorganic & Medicinal Chemistry Letters. 22:7702-7706
مصطلحات موضوعية: medicine.drug_class, Drug discovery, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, hemic and immune systems, Pharmacology, Receptor antagonist, Biochemistry, Small molecule, In vitro, chemistry.chemical_compound, chemistry, immune system diseases, Drug Discovery, medicine, Molecular Medicine, Structure–activity relationship, Potency, Receptor, Molecular Biology, Lead compound
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المؤلفون: Aaron Rigby, Peter J. H. Webborn, Rob Riley, John Collington, Mark Furber, Brian Springthorpe, Matt Soars, Ash Bahl, Cathy MacDonald, Keith Bowers, Elizabeth Kinchin, Lilian Alcaraz, Rebecca Denton, Haydn Beaton, David Donald, Christopher A. Luckhurst
المصدر: Bioorganic & Medicinal Chemistry Letters. 22:7707-7710
مصطلحات موضوعية: Liver chemistry, medicine.drug_class, Drug discovery, Chemistry, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Dual inhibitor, Pharmaceutical Science, Receptor antagonist, Biochemistry, Liver metabolism, In vivo, Drug Discovery, medicine, Molecular Medicine, Structure–activity relationship, Tissue distribution, Molecular Biology
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المؤلفون: Celia Dominguez, Marieke Lamers, Samantha J. Hughes, Rebecca E. Jarvis, Grant Wishart, Helen L. Birch, Roland Bürli, Omar Aziz, Scott Pollack, Dawn Yates, Perla Breccia, Christopher A. Luckhurst, Philip Leonard, Andrew J. Stott, George McAllister, Kim L. Matthews, Elizabeth Anne Saville-Stones
مصطلحات موضوعية: 0301 basic medicine, Hydroxamic acid, Cyclopropanation, Organic Chemistry, Pharmacology, Biochemistry, Cyclopropane, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, chemistry, Drug Discovery, Hydrolase, Histone deacetylase, Penetrant (biochemical)
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2917976f54e5700b574a852afba864e3
https://europepmc.org/articles/PMC4716601/ -
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المصدر: Tetrahedron Letters. 48:8878-8882
مصطلحات موضوعية: In situ, endocrine system, Chemistry, Organic Chemistry, Drug Discovery, technology, industry, and agriculture, nutritional and metabolic diseases, food and beverages, Organic chemistry, Biochemistry, hormones, hormone substitutes, and hormone antagonists, Curtius rearrangement
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المؤلفون: Rupert P. Austin, Karl Edman, Hitesh J. Sanganee, Raj Beri, Peter Cage, Christopher A. Luckhurst, Jason Breed, Ian Millichip, Victor I. C. Oreffo, Bob Thong, Antonio Mete, Kamaldeep K. Chohan, Steve T. Harper, Alan V. Wallace, Elizabeth Kinchin, Lisa Wissler, Judit E. Debreczeni, Andrew Mather, Anna-Karin Tidén, Mark Furber, Rhonan Ford, Ray Hutchinson, Simon Barber, Philip Gardiner, Linda Stein
المصدر: Journal of medicinal chemistry. 57(6)
مصطلحات موضوعية: Models, Molecular, Chemistry, Molecular Conformation, Highly selective, Molecular conformation, Cathepsin C, Recombinant Proteins, Substrate Specificity, Structure-Activity Relationship, Spectrometry, Fluorescence, Biochemistry, X-Ray Diffraction, In vivo, Drug Discovery, Molecular Medicine, Structure–activity relationship, Substrate specificity, Humans, Indicators and Reagents, Protease Inhibitors