المؤلفون: Daniel J Fazakerley, Rima Chaudhuri, Pengyi Yang, Ghassan J Maghzal, Kristen C Thomas, James R Krycer, Sean J Humphrey, Benjamin L Parker, Kelsey H Fisher-Wellman, Christopher C Meoli, Nolan J Hoffman, Ciana Diskin, James G Burchfield, Mark J Cowley, Warren Kaplan, Zora Modrusan, Ganesh Kolumam, Jean YH Yang, Daniel L Chen, Dorit Samocha-Bonet, Jerry R Greenfield, Kyle L Hoehn, Roland Stocker, David E James

المصدر: eLife, Vol 7 (2018)

مصطلحات موضوعية: Insulin resistance, Mitochondria, Oxidants, Coenzyme Q, Insulin, Ubiquinone, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/32111; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/8a5796fc74b24c25b9c3c989e6b15e61

المؤلفون: Christopher C. Meoli, James G. Burchfield, Sheyda Naghiloo, Matthew J. Prior, Daniel J. Fazakerley, Benjamin L. Parker, Jacqueline Stöckli, Rima Chaudhuri, David E. James, Beverley A. Murrow, Geoffrey D. Holman, James R. Krycer, Kristen C. Thomas, Francoise Koumanov

المساهمون: Fazakerley, Daniel [0000-0001-8241-2903], Apollo - University of Cambridge Repository

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: Male, Proteomics, medicine.medical_specialty, insulin, Glucose uptake, medicine.medical_treatment, Peroxisome proliferator-activated receptor, adipocyte, Biochemistry, 03 medical and health sciences, Mice, 0302 clinical medicine, Insulin resistance, Internal medicine, Insulin receptor substrate, insulin resistance, 3T3-L1 Cells, medicine, Adipocytes, tumor suppressor candidate 5 (TUSC5), Animals, glucose transporter type 4 (GLUT4), Rats, Wistar, Molecular Biology, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Glucose Transporter Type 4, biology, Insulin, membrane trafficking, Tumor Suppressor Proteins, Glucose transporter, Cell Biology, medicine.disease, Rats, Insulin receptor, Endocrinology, chemistry, biology.protein, 030217 neurology & neurosurgery, GLUT4

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4279b46ef8cebac018eec3bec47ba458
http://europepmc.org/articles/PMC4583025

المؤلفون: P. Tess Whitworth, Ee Cheng Khor, Kyle L. Hoehn, Xiuquan Ma, James Cantley, Belinda Yau, Christopher C. Meoli, James G. Burchfield, Natalie K.Y. Wee, Jacqueline Stöckli, James R. Krycer, Shi-Xlong Tan, Annabel Y. Minard, Paul A. Baldock, Nolan J. Hoffman, Daniel J. Fazakerley, Marin E. Nelson, Trevor J. Biden, Gregory J. Cooney, Amanda L. Wright, Ronaldo F. Enriquez, Melkam A. Kebede, Kristen C. Thomas, David E. James, Bryce Vissel

مصطلحات موضوعية: 0301 basic medicine, Male, Sucrose, obesity, Time Factors, muscle, medicine.medical_treatment, Adipose tissue, Biochemistry, deposition, Mice, Hyperinsulinemia, Glucose homeostasis, Western diet, glucose, diabetes, Leptin, neurodegeneration, secretion, nutrition, medicine.medical_specialty, Biochemistry & Molecular Biology, insulin, glucose metabolism, Carbohydrate metabolism, leptin, diseases, 03 medical and health sciences, Insulin resistance, Metabolic Diseases, Diabetes mellitus, Internal medicine, medicine, Dietary Carbohydrates, Animals, Bone, deterioration, Molecular Biology, business.industry, Insulin, beta cell(B-cell), Telomere Homeostasis, Cell Biology, medicine.disease, Dietary Fats, 030104 developmental biology, Endocrinology, business, metabolism, medical problems

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c71f02bc8840d707632c2abc83e61c6c
https://acuresearchbank.acu.edu.au/item/8qx48/high-dietary-fat-and-sucrose-results-in-an-extensive-and-time-dependent-deterioration-in-health-of-multiple-physiological-systems-in-mice

المؤلفون: Kyle L. Hoehn, Jerry R. Greenfield, Warren Kaplan, Ganesh Kolumam, James G. Burchfield, David E. James, Nolan J. Hoffman, Daniel L. T Chen, Jean Yh Yang, Ciana Diskin, Kelsey H. Fisher-Wellman, Sean J. Humphrey, Ghassan J. Maghzal, Kristen C. Thomas, Benjamin L. Parker, James R. Krycer, Zora Modrusan, Rima Chaudhuri, Roland Stocker, Daniel J. Fazakerley, Pengyi Yang, Dorit Samocha-Bonet, Christopher C. Meoli, Mark J. Cowley

المساهمون: Fazakerley, Daniel J [0000-0001-8241-2903], James, David E [0000-0001-5946-5257], Apollo - University of Cambridge Repository

المصدر: eLife, Vol 7 (2018)
eLife

مصطلحات موضوعية: 0301 basic medicine, Mitochondrial Diseases, Mouse, Ubiquinone, medicine.medical_treatment, Respiratory chain, Adipose tissue, Mitochondrion, Mice, chemistry.chemical_compound, Adipocytes, Insulin, Glucose homeostasis, Biology (General), Muscle Weakness, Chemistry, Superoxide, Muscles, General Neuroscience, human biology, food and beverages, General Medicine, Oxidants, Mitochondria, 3. Good health, Adipose Tissue, Medicine, Research Article, Human, medicine.medical_specialty, QH301-705.5, Science, Sensitivity and Specificity, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Insulin resistance, Internal medicine, medicine, Animals, Humans, Human Biology and Medicine, General Immunology and Microbiology, Coenzyme Q, Cell Biology, medicine.disease, 030104 developmental biology, Endocrinology, Coenzyme Q – cytochrome c reductase, Ataxia

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3f4f9362349b13b51a6a6ef1d39528a
https://acuresearchbank.acu.edu.au/item/8q630/mitochondrial-coq-deficiency-is-a-common-driver-of-mitochondrial-oxidants-and-insulin-resistance

المؤلفون: Daniel J Fazakerley, Rima Chaudhuri, Pengyi Yang, Ghassan J Maghzal, Kristen C Thomas, James R Krycer, Sean J Humphrey, Benjamin L Parker, Kelsey H Fisher-Wellman, Christopher C Meoli, Nolan J Hoffman, Ciana Diskin, James G Burchfield, Mark J Cowley, Warren Kaplan, Zora Modrusan, Ganesh Kolumam, Jean YH Yang, Daniel L Chen, Dorit Samocha-Bonet, Jerry R Greenfield, Kyle L Hoehn, Roland Stocker, David E James

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::dd9dfd56169a522c67aa9961c46fd768
https://doi.org/10.7554/elife.32111.032

المؤلفون: Salvatore P. Mangiafico, Kari Wong, Olga Ilkayeva, Nolan J. Hoffman, Daniel J. Fazakerley, Jacqueline Stöckli, Chrysovalantou E. Xirouchaki, Chieh Hsin Yang, Gregory J. Cooney, Xiao Yi Zeng, Christopher C. Meoli, Kristen C. Thomas, Sofianos Andrikopoulos, David E. James, Kelsey H. Fisher-Wellman, Rima Chaudhuri, Deborah M. Muoio

المصدر: The Journal of biological chemistry. 292(47)

مصطلحات موضوعية: 0301 basic medicine, Male, Metabolite, 030209 endocrinology & metabolism, Mice, Inbred Strains, Biology, Carbohydrate metabolism, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Metabolomics, Insulin resistance, Inbred strain, Polymorphism (computer science), Metabolome, medicine, Animals, Molecular Biology, Genetics, Computational Biology, Cell Biology, medicine.disease, Phenotype, Diet, 030104 developmental biology, Metabolism, chemistry, Insulin Resistance

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7282bb338fb7edbe784f51aca86ef46
https://pubmed.ncbi.nlm.nih.gov/28982973

المؤلفون: James G. Burchfield, Sofianos Andrikopoulos, Lindsay E. Wu, David E. James, David G. Le Couteur, Chrysovalantou E. Xirouchaki, Myung Jin Kang, Elizabeth E. Powter, Ganesh Kolumam, Daniel J. Fazakerley, Salvatore P. Mangiafico, Nicholas van Bruggen, Mashani Mohamad, Victoria C. Cogger, Jacqueline Stöckli, Himani Pant, A. Stefanie Mikolaizak, Jennifer R. Gamble, Gregory J. Cooney, Christopher C. Meoli

المصدر: Diabetes. 63:2656-2667

مصطلحات موضوعية: Male, Vascular Endothelial Growth Factor A, medicine.medical_specialty, Angiogenesis, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Adipose tissue, Carbohydrate metabolism, Antibodies, Mice, chemistry.chemical_compound, Insulin resistance, Internal medicine, Genetic model, Internal Medicine, medicine, Animals, Homeostasis, Insulin, Obesity, Adiposity, biology, medicine.disease, Animal Feed, Dietary Fats, Vascular endothelial growth factor, Insulin receptor, Glucose, Endocrinology, Liver, chemistry, Immunoglobulin G, biology.protein, Insulin Resistance, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8a4fe262a0b7f82595c74d6506b05b4
https://doi.org/10.2337/db13-1665

المؤلفون: Alexander J. Groffen, James G. Burchfield, James Cantley, Himani Pant, P.T. Whitworth, David E. James, Jia Li, Christopher C. Meoli, Rima Chaudhuri, Jacqueline Stöckli, Matthijs Verhage

المساهمون: Functional Genomics, Neuroscience Campus Amsterdam - Brain Mechanisms in Health & Disease, Human genetics, NCA - Brain mechanisms in health and disease

المصدر: Li, J, Cantley, J, Burchfield, J G, Meoli, C C, Stöckli, J, Whitworth, P T, Pant, H, Chaudhuri, R, Groffen, A J A, Verhage, M & James, D E 2014, ' DOC2 isoforms play dual roles in insulin secretion and insulin-stimulated glucose uptake ', Diabetologia, vol. 57, no. 10, pp. 2173-2182 . https://doi.org/10.1007/s00125-014-3312-y
Diabetologia, 57(10), 2173-2182. Springer Verlag

مصطلحات موضوعية: Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Glucose uptake, medicine.medical_treatment, Nerve Tissue Proteins, Exocytosis, Mice, SDG 3 - Good Health and Well-being, Internal medicine, Insulin Secretion, Adipocytes, Internal Medicine, medicine, Animals, Insulin, Glucose homeostasis, Mice, Knockout, biology, Calcium-Binding Proteins, Biological Transport, Intracellular vesicle, Insulin receptor, Glucose, Endocrinology, biology.protein, Beta cell, GLUT4

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afeea4570fd87190623f5093f2b0195d
https://doi.org/10.1007/s00125-014-3312-y

المؤلفون: Gordon J. King, Shu-Hong Hu, Andrew E. Whitten, Jagath Reddy Junutula, Jacqueline Stöckli, Christopher C. Meoli, David E. James, Russell Jarrott, Brit Winnen, Jennifer L. Martin, Wilko Duprez

المصدر: Journal of Biological Chemistry. 287:40996-41006

مصطلحات موضوعية: Surface Properties, Molecular Sequence Data, Static Electricity, Calorimetry, Biology, Crystallography, X-Ray, Phosphatidylinositols, Biochemistry, GTP Phosphohydrolases, Protein–protein interaction, Protein structure, Protein Interaction Mapping, Humans, Scattering, Radiation, Small GTPase, Amino Acid Sequence, Cloning, Molecular, Molecular Biology, Adaptor Proteins, Signal Transducing, Monomeric GTP-Binding Proteins, Cell Nucleus, Binding Sites, Sequence Homology, Amino Acid, X-Rays, Cell Membrane, Signal transducing adaptor protein, Isothermal titration calorimetry, Cell Biology, Protein Structure, Tertiary, Pleckstrin homology domain, Kinetics, rab GTP-Binding Proteins, Membrane curvature, Protein Structure and Folding, Solvents, Biophysics, Rab, Crystallization, Dimerization, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eb9b1618c07c2918e8170a5ace3e9cd
https://doi.org/10.1074/jbc.m112.349803

المؤلفون: Yvonne Ng, Adelle C.F. Coster, Shi-Xiong Tan, Christopher C. Meoli, Himani Pant, Daniel J. Fazakerley, Jacqueline Stöckli, David E. James, Jia Li, Kelsey H. Fisher-Wellman

مصطلحات موضوعية: medicine.medical_specialty, Glucose uptake, medicine.medical_treatment, Adipose Tissue, White, Diet, High-Fat, Biochemistry, chemistry.chemical_compound, Mice, Insulin resistance, Internal medicine, Adipocyte, 3T3-L1 Cells, medicine, Adipocytes, Animals, Insulin, RNA, Small Interfering, Molecular Biology, Protein kinase B, PI3K/AKT/mTOR pathway, biology, Biological Transport, Cell Biology, medicine.disease, Enzyme Activation, Insulin receptor, Endocrinology, Glucose, chemistry, Gene Knockdown Techniques, biology.protein, Insulin Resistance, Proto-Oncogene Proteins c-akt, GLUT4, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b3f58f782eb5dbfdd36190fbf2b1a3
https://europepmc.org/articles/PMC4416839/