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المؤلفون: Iacovos N Michaelides, Christopher D. Stubbs, Puneet Khurana, Kun Song, Kevin J. Embrey, R. Ian Storer, Christopher R. Phillips, Gavin W. Collie, Ian L. Dale, Arjan Snijder, Louise Barlind, Ulf Börjesson
المصدر: ACS Medicinal Chemistry Letters
مصطلحات موضوعية: C-Met, kinase, Chemistry, Kinase, Stereochemistry, Organic Chemistry, small molecule inhibitor, Biochemical Activity, Note, Chemical basis, P-loop, Biochemistry, Cell activity, chemistry.chemical_compound, Drug Discovery, c-MET, X-ray crystallography
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المؤلفون: Alice R Eddershaw, Karl Syson, Paul R. J. Davey, Gregory Hamm, Christopher D. Stubbs, Paul Clarkson, Elizabeth Underwood, Lucy V Edwardes
المصدر: Biochemistry. 59:4775-4786
مصطلحات موضوعية: Models, Molecular, Protein-Arginine N-Methyltransferases, Methyltransferase, Arginine, In Vitro Techniques, Biochemistry, Mass Spectrometry, Substrate Specificity, 03 medical and health sciences, Protein structure, Catalytic Domain, Humans, Protein Interaction Domains and Motifs, Amino Acid Sequence, Enzyme Inhibitors, Protein Structure, Quaternary, Ternary complex, Adaptor Proteins, Signal Transducing, 0303 health sciences, Chemistry, Protein arginine methyltransferase 5, 030302 biochemistry & molecular biology, Deuterium Exchange Measurement, Recombinant Proteins, Kinetics, Biophysics, Hydrogen–deuterium exchange, Steady state (chemistry)
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المؤلفون: J. Mark Skehel, Ian L. Dale, Mark S. B. McAlister, Christopher D. Stubbs, Francesca Malvezzi, Jon P. DeGnore, Thomas A. Jowitt, Xieyang Guo, Andrew J. Bannister, Gianluca Degliesposti
المساهمون: Skehel, J Mark [0000-0002-2432-0901], Bannister, Andrew J [0000-0002-6312-4436], McAlister, Mark S [0000-0003-3986-1767], Apollo - University of Cambridge Repository, Bannister, Andrew [0000-0002-6312-4436]
المصدر: Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Communications Biologyمصطلحات موضوعية: 82/29, Conformational change, BRD4, QH301-705.5, Biophysics, Medicine (miscellaneous), Cell Cycle Proteins, Article, Supramolecular assembly, General Biochemistry, Genetics and Molecular Biology, 14/33, Transcription (biology), 631/57/2272/2276, Humans, Biology (General), Phosphorylation, Casein Kinase II, 82/83, 631/57, 82/16, Chemistry, 82/58, Chromatin, Bromodomain, Cell biology, Structural biology, Gene Expression Regulation, 9, Casein kinase 2, General Agricultural and Biological Sciences, 631/535, Transcription Factors
وصف الملف: application/pdf; text/xml; application/zip
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed0831170bd5bba64f873b650d080de1
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المؤلفون: Carlos Sanchez-Cano, Sébastien Perrier, Joji Tanaka, Daniel W. Lester, Pratik Gurnani, Christopher D. Stubbs, Thomas Floyd
المصدر: Polymer Chemistry. 11:1230-1236
مصطلحات موضوعية: chemistry.chemical_classification, Molar mass, Polymers and Plastics, Organic Chemistry, Bioengineering, Nanotechnology, 02 engineering and technology, Polymer, Raft, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, Biochemistry, 0104 chemical sciences, chemistry.chemical_compound, Monomer, Polymerization, chemistry, Drug delivery, 0210 nano-technology, Throughput (business), Macromolecule
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::cf25899b68c4647b42057f2793bb2460
https://doi.org/10.1039/c9py01521c -
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المؤلفون: Cheryl M. Koh, Christopher D. Stubbs, Puneet Khurana, Gavin W. Collie, Ian L. Dale, Alice R Eddershaw, Joseph Shaw, Fredrik Mauritzson, Tony Cheung, Arjan Snijder, Edward J. Hennessy, Christopher R. Phillips, Louise Barlind, Daniel O'Neill, Ana J. Narvaez
المصدر: ACS Medicinal Chemistry Letters
مصطلحات موضوعية: Letter, cMET, kinase, Mutant, medicine.disease_cause, 01 natural sciences, Biochemistry, Receptor tyrosine kinase, Drug Discovery, medicine, Transferase, X-ray crystallography, Mutation, drug resistance, biology, 010405 organic chemistry, Kinase, Chemistry, Organic Chemistry, small molecule inhibitor, Small molecule, First generation, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Savolitinib, Cancer research, biology.protein
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المؤلفون: Gabriele C. Sosso, Christopher D. Stubbs, Thomas R. Congdon, Matthew I. Gibson, Fabienne Bachtiger
المصدر: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)مصطلحات موضوعية: TP, Computational chemistry, Materials science, Science, Chemical physics, General Physics and Astronomy, 02 engineering and technology, 010402 general chemistry, urologic and male genital diseases, 01 natural sciences, General Biochemistry, Genetics and Molecular Biology, Article, Molecular dynamics, QD, cardiovascular diseases, QC, Multidisciplinary, integumentary system, urogenital system, fungi, General Chemistry, 021001 nanoscience & nanotechnology, QP, female genital diseases and pregnancy complications, 0104 chemical sciences, Atomistic models, 0210 nano-technology, Effective volume
وصف الملف: application/pdf
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المؤلفون: Matthew I. Gibson, Trisha L. Bailey, Christopher D. Stubbs, Ruben M F Tomás, Lucienne Otten, Kathryn Murray
المصدر: Biomacromolecules
مصطلحات موضوعية: Lung Neoplasms, Polymers and Plastics, Cryoprotectant, Cell Survival, Cell, Bioengineering, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, Article, Cryopreservation, Biomaterials, Cell membrane, chemistry.chemical_compound, Cryoprotective Agents, Tumor Cells, Cultured, Materials Chemistry, medicine, Humans, Dimethyl Sulfoxide, QD, chemistry.chemical_classification, Dimethyl sulfoxide, QH, Cell Membrane, Maleates, Polymer, 021001 nanoscience & nanotechnology, QP, 0104 chemical sciences, Solvent, medicine.anatomical_structure, Membrane, chemistry, Biophysics, Polyethylenes, 0210 nano-technology
وصف الملف: application/pdf
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المؤلفون: Joseph Shaw, Christopher D. Stubbs
المصدر: Protein-Ligand Interactions ISBN: 9781071611968
مصطلحات موضوعية: 0301 basic medicine, Thermal shift assay, Chemistry, A protein, 02 engineering and technology, 021001 nanoscience & nanotechnology, Fluorescence spectroscopy, Cellular protein, law.invention, 03 medical and health sciences, 030104 developmental biology, law, Thermal, Biophysics, Recombinant DNA, Thermal stability, 0210 nano-technology, Intracellular
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::36370344693318bb17e6b40d483f3431
https://doi.org/10.1007/978-1-0716-1197-5_8 -
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المؤلفون: Matthew I. Gibson, Daniel W. Lester, Thomas R. Congdon, Jessica Davis, Christopher D. Stubbs, Sarah-Jane Richards
المصدر: Macromolecules
مصطلحات موضوعية: chemistry.chemical_classification, Materials science, Polymers and Plastics, Tertiary amine, Organic Chemistry, Dispersity, Chain transfer, 02 engineering and technology, Polymer, 010402 general chemistry, 021001 nanoscience & nanotechnology, Ascorbic acid, 01 natural sciences, Combinatorial chemistry, Article, 0104 chemical sciences, Inorganic Chemistry, Photopolymer, chemistry, Polymerization, Materials Chemistry, QD, 0210 nano-technology, Deoxygenation
وصف الملف: application/pdf
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المؤلفون: Marianne Schimpl, Nicola Lawson, Carly I. Dix, Edmond Wong, Craig Barker, Liam Hutchinson, Eileen McCall, Jill Walker, Paul Scorer, Christopher D. Stubbs, Emma DeVries, James K. Hunt, Gareth H. Williams
المصدر: Modern Pathology
مصطلحات موضوعية: 0301 basic medicine, Pathology, medicine.medical_specialty, Glycosylation, Cancer immunotherapy, Plasma protein binding, Predictive markers, Epitope, Article, Antibodies, B7-H1 Antigen, Pathology and Forensic Medicine, law.invention, 03 medical and health sciences, 0302 clinical medicine, Antineoplastic Agents, Immunological, law, Antibody Specificity, Predictive Value of Tests, Neoplasms, medicine, Humans, Binding site, Immune Checkpoint Inhibitors, biology, Chemistry, Reproducibility of Results, Correction, Molecular biology, Immunohistochemistry, Blot, 030104 developmental biology, Epitope mapping, 030220 oncology & carcinogenesis, Mutation, biology.protein, Recombinant DNA, Binding Sites, Antibody, Antibody, Epitope Mapping, Protein Binding