المؤلفون: Anja Charlotte Lundgren Mortensen, Diana Spiegelberg, Christopher John Brown, David Philip Lane, Marika Nestor

المصدر: Frontiers in Oncology, Vol 9 (2019)

مصطلحات موضوعية: p53, wild-type p53, radiosensitization, external beam radiation therapy (EBRT), PM2, spheroid apoptosis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fonc.2019.00923/full; https://doaj.org/toc/2234-943X

URL الوصول: https://doaj.org/article/625d8ae824cf4fb8841b5f0c06ec12c1

المؤلفون: Wei Mei Guo, Kiat Whye Kong, Christopher John Brown, Soo Tng Quah, Hui Ling Yeo, Shawn Hoon, Yiqi Seow

المصدر: Molecular Therapy: Nucleic Acids, Vol 3, Iss C (2014)

مصطلحات موضوعية: Aptamer, eIF4e, SELEX, proliferation, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2162253116303560; https://doaj.org/toc/2162-2531

URL الوصول: https://doaj.org/article/ab266facd68b4c91ac904f9c7717649b

المؤلفون: Michael Prime, Samantha Green, Celia Dominguez, Edith Monteagudo, Malcolm Taylor, Akihiro Takano, Longbin Liu, Adrian Kotey, Wayne Thomas, Zhisheng Jia, Anthony P Dickie, Catherine Greenaway, Samuel Coe, Miklós Tóth, John Wityak, Vinod Khetarpal, Sergio Menta, Simone Esposito, Katarina Vanräs, Andreas Ebneth, John E. Mangette, Ian Wigginton, Todd Herbst, Peter Johnson, Sabine Schaertl, Vladimir Stepanov, Jonathan Bard, Sebastien Galan, Elise Gadouleau, Randall Davis, Christopher John Brown, Frank Herrmann, Richard W Marston, Darshan Gunvant Vaidya, Laura Orsatti, Xuemei Chen, Martina Nibbio, Manuela Heßmann, Joanne Sproston, Matthew R Mills, Ignacio Munoz-Sanjuan, Daniel Clark-Frew, Derek Alexander Weddell, Ladislav Mrzljak, Christoph Scheich, Xinjie Gai, Christer Halldin, Sangram Nag, Lee Matthew, Patricia Miranda-Azpiazu, Paul Giles, Thomas Krulle, Alexander Kiselyov, Marie Svedberg, Sarah Hayes

المصدر: Journal of medicinal chemistry. 63(15)

مصطلحات موضوعية: Male, Huntingtin, Imaging biomarker, Mutant, Protein aggregation, medicine.disease_cause, Ligands, 01 natural sciences, Protein Aggregation, Pathological, Madin Darby Canine Kidney Cells, Rats, Sprague-Dawley, 03 medical and health sciences, Mice, Dogs, Drug Discovery, medicine, Animals, Humans, 030304 developmental biology, 0303 health sciences, Mutation, Huntingtin Protein, medicine.diagnostic_test, Chemistry, Ligand (biochemistry), 0104 chemical sciences, Cell biology, Mice, Inbred C57BL, 010404 medicinal & biomolecular chemistry, Disease Models, Animal, Huntington Disease, Positron emission tomography, Positron-Emission Tomography, Molecular Medicine, Female, Efflux, Radiopharmaceuticals, Peptides

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44bbb7331f2e0517d6d294883abdcc6f
https://pubmed.ncbi.nlm.nih.gov/32662649

المؤلفون: Leticia Toledo-Sherman, Catherine M. O'Connell, Christopher John Yarnold, Michael Prime, Suganathan Selvaratnam, Ignacio Munoz-Sanjuan, Ladislav Mrzljak, Arash Rassoulpour, Kimberly L Matthews, Patricia Wheelan, Laura Reed, Wolfgang Reindl, Alan Beresford, Estelle Hamelin-Flegg, Derek Alexander Weddell, William L. Mitchell, Dawn Yates, Maria Beconi, Weslyn Ward Friley, Christopher John Brown, Christin Winkler, Stephen Martin Courtney, Valerie Kempf, John Wityak, Naomi Went, Celia Dominguez, Isabell Cardaun, Kendall D. Powell, Ulrike Dijkman, Peter Johnson, Frederick Arthur Brookfield, Dirk Winkler, De Aguiar Pena Paula C, Kathy Lyons

المصدر: Journal of medicinal chemistry. 58(3)

مصطلحات موضوعية: Models, Molecular, Kynurenine pathway, Pyrimidine, CHO Cells, Pharmacology, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Cricetulus, Kynurenine 3-Monooxygenase, In vivo, Drug Discovery, Animals, Humans, Enzyme Inhibitors, Kynurenine, ADME, Cell Proliferation, chemistry.chemical_classification, Dose-Response Relationship, Drug, Molecular Structure, Monooxygenase, Rats, Enzyme, Huntington Disease, Pyrimidines, chemistry, Biochemistry, Molecular Medicine, Lead compound

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::699f24106f0a18d2d3d4ac5e1d3ff8ca
https://pubmed.ncbi.nlm.nih.gov/25590515

المؤلفون: Christopher John Brown, Lee Hui Jun, Deepa Srinivasan, David P. Lane, David Coomber, Chandra S. Verma

المصدر: Cell Cycle. 7:608-610

مصطلحات موضوعية: Models, Molecular, Phosphopeptides, Static Electricity, Mutant, Fluorescence Polarization, Peptide, Biology, Crystallography, X-Ray, medicine.disease_cause, Structure-Activity Relationship, medicine, Phosphorylation, neoplasms, Molecular Biology, chemistry.chemical_classification, Mutation, Proto-Oncogene Proteins c-mdm2, Cell Biology, Electrostatics, Fluorescence, enzymes and coenzymes (carbohydrates), Biochemistry, chemistry, biology.protein, Mdm2, Tumor Suppressor Protein p53, Protein Binding, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fed92e9389684f40ea945ff4d4ec5a50
https://doi.org/10.4161/cc.7.5.5488

المؤلفون: Christopher John Brown, Mohamed Ahmed Mashaal, Tom Fuller, Robert Paterson

المصدر: Day 1 Mon, September 30, 2013.

مصطلحات موضوعية: Petroleum engineering, Field (physics), Drilling, Casing, Geology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2f704f332d6986fdb3edeac46aa98b29
https://doi.org/10.2118/166170-ms

المؤلفون: David P, Lane, Christopher John, Brown, Chandra, Verma, Chit Fang, Cheok

المصدر: Discovery medicine. 12(63)

مصطلحات موضوعية: Neoplasms, Animals, Humans, Tumor Suppressor Protein p53, Models, Biological

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::50302161e29f26f16f40d100fac60059
https://pubmed.ncbi.nlm.nih.gov/21878188