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1دورية أكاديمية
المؤلفون: Yunhao Tan, Kenta Mosallanejad, Qingxiu Zhang, Stephen O’Brien, Meghan Clements, Stuart Perper, Sarah Wilson, Sudiksha Chaulagain, Jing Wang, Mary Abdalla, Helen Al-Saidi, Danyal Butt, Anca Clabbers, Kwasi Ofori, Beth Dillon, Bohdan Harvey, John Memmott, Christopher Negron, David Winarta, Catherine Tan, Amlan Biswas, Feng Dong, Vanessa Morales-Tirado, Xiaoqing Lu, Gurminder Singh, Michael White, Shanna Ashley, Heather Knight, Susan Westmoreland, Lucy Phillips, Tracy Carr, Lauren Reinke-Breen, Rajeeva Singh, Jianwen Xu, Kan Wu, Lisa Rinaldi, Brian Stoll, Yupeng David He, Lisa Hazelwood, Jozsef Karman, Andrew McCluskey, William Stine, Ivan Correia, Stephen Gauld, Marc C. Levesque, Geertruida Veldman, Cedric Hubeau, Timothy Radstake, Ramkrishna Sadhukhan, Edda Fiebiger
المصدر: Frontiers in Immunology, Vol 15 (2024)
مصطلحات موضوعية: IL11, fibrosis, drug target, STAT3, ERK, stromal cell, Immunologic diseases. Allergy, RC581-607
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: Christopher Negron, Joyce Fang, Michael J. McPherson, W. Blaine Stine, Andrew J. McCluskey
المصدر: mAbs, Vol 14, Iss 1 (2022)
مصطلحات موضوعية: Developability, drug discovery, machine learning, repertoire antibodies, therapeutic antibodies, Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607
وصف الملف: electronic resource
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3دورية أكاديمية
المؤلفون: Davide Tavella, David R Ouellette, Raffaella Garofalo, Kai Zhu, Jianwen Xu, Eliud O Oloo, Christopher Negron, Peter M Ihnat
المصدر: PLoS ONE, Vol 17, Iss 12, p e0279689 (2022)
وصف الملف: electronic resource
Relation: https://doaj.org/toc/1932-6203
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4دورية أكاديمية
المؤلفون: Christopher Negron, David A Pearlman, Guillermo Del Angel
المصدر: PLoS ONE, Vol 14, Iss 3, p e0214015 (2019)
وصف الملف: electronic resource
Relation: https://doaj.org/toc/1932-6203
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المؤلفون: Xin Yu, Christopher Negron, Lili Huang, Geertruida Veldman
المصدر: Antibody Therapeutics.
مصطلحات موضوعية: Immunology, Immunology and Allergy
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f5bc114bc29de29b44cf849c8118d34b
https://doi.org/10.1093/abt/tbad011 -
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المؤلفون: Christopher Negron, Wenting Ma, Alexey Teplyakov, Winnie Chan, Sandeep Somani, Thomas J. Malia, Lauren E. Boucher, Gary L. Gilliland, Jinquan Luo, Galina Obmolova, Steven Jacobs
المصدر: Proteins: Structure, Function, and Bioinformatics. 90:270-281
مصطلحات موضوعية: Hot Temperature, Protein Stability, Chemistry, Fibronectin Type III Domain, Protein domain, Beta sheet, Thermoanaerobacter, Cooperativity, Calorimetry, Molecular Dynamics Simulation, Sodium Chloride, Biochemistry, Free energy perturbation, Crystallography, Molecular dynamics, Differential scanning calorimetry, Bacterial Proteins, Protein Domains, Structural Biology, Salt bridge, Molecular Biology
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7
المؤلفون: Anthony J. Clark, Richard A. Friesner, Mengzhen Sun, Robert Abel, Lingle Wang, Christopher Negron, Kevin Hauser
المصدر: Journal of Molecular Biology
مصطلحات موضوعية: Databases, Factual, Entropy, HIV Antibodies, HIV Envelope Protein gp120, Molecular Dynamics Simulation, Ligands, Article, Biophysical Phenomena, Accessible surface area, Free energy perturbation, FEP, free energy perturbation, 03 medical and health sciences, 0302 clinical medicine, Protein structure, RMSE, root mean square error, Structural Biology, Drug Discovery, Side chain, antibodies, Protein Interaction Domains and Motifs, free energy perturbation, Molecular Biology, bNAb, broadly neutralizing antibody, SKEMPI, Structural database of Kinetics and Energetics of Mutant Protein Interactions, 030304 developmental biology, 0303 health sciences, Sequence, Chemistry, MM, molecular mechanics, fSASA, fractional solvent accessible surface area, Computational Biology, Proteins, Charge (physics), Hydrogen Bonding, Protein engineering, Small molecule, MD, molecular dynamics, Antibodies, Neutralizing, protein-protein binding, Mutation, mm-GB/SA, molecular mechanics generalized Born surface area, Biological system, 030217 neurology & neurosurgery, Protein Binding
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المؤلفون: Guillermo del Angel, Christopher Negron, Etienne Mornet, John Reynders, Thomas Steinbrecher
المصدر: Human Mutation
مصطلحات موضوعية: In silico, Mutation, Missense, rare disease, Computational biology, Gene mutation, Biology, medicine.disease_cause, algorithms, 03 medical and health sciences, tissue‐nonspecific alkaline phosphatase, hypophosphatasia, Genetics, medicine, Missense mutation, Humans, Genetics (clinical), Research Articles, 030304 developmental biology, 0303 health sciences, Mutation, 030305 genetics & heredity, Hypophosphatasia, ALPL, medicine.disease, Alkaline Phosphatase, Phenotype, Protein Structure, Tertiary, Alkaline phosphatase, variant effect prediction, genetic data bases
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9
المؤلفون: David A. Pearlman, Guillermo del Angel, Christopher Negron
المصدر: PLoS ONE
PLoS ONE, Vol 14, Iss 3, p e0214015 (2019)مصطلحات موضوعية: Future studies, medicine.disease_cause, Biochemistry, Database and Informatics Methods, 0302 clinical medicine, Databases, Genetic, Enzyme Stability, Missense mutation, Amino Acids, 0303 health sciences, Protein function, Mutation, Multidisciplinary, Crystallography, Drug discovery, Organic Compounds, Physics, Condensed Matter Physics, Chemistry, Deletion Mutation, Physical Sciences, Crystal Structure, Medicine, Basic Amino Acids, Sequence Analysis, Research Article, Substitution Mutation, Missense Mutation, Bioinformatics, Science, Mutation, Missense, Computational biology, Arginine, Research and Analysis Methods, beta-Lactamases, 03 medical and health sciences, Bacterial Proteins, medicine, Genetics, Solid State Physics, Sulfur Containing Amino Acids, Humans, Cysteine, Gene, 030304 developmental biology, Point mutation, Lysine, Organic Chemistry, Chemical Compounds, Biology and Life Sciences, Proteins, Genes, Bacterial, Sequence Alignment, 030217 neurology & neurosurgery, Function (biology)
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10
المؤلفون: Christopher Negron, Soumya S. Ray, John D. Chodera, Kevin Hauser, Robert Abel, Lingle Wang, Steven K. Albanese, Thomas Steinbrecher
المصدر: Communications Biology, Vol 1, Iss 1, Pp 1-14 (2018)
مصطلحات موضوعية: 0301 basic medicine, Drug, media_common.quotation_subject, Medicine (miscellaneous), General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, 0302 clinical medicine, medicine, Potency, Missense mutation, lcsh:QH301-705.5, 030304 developmental biology, media_common, 0303 health sciences, ABL, Chemistry, Kinase, Point mutation, Cancer, medicine.disease, 3. Good health, 030104 developmental biology, lcsh:Biology (General), 030220 oncology & carcinogenesis, Cancer research, A kinase, General Agricultural and Biological Sciences, Chronic myelogenous leukemia
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f45ebfb6d0c45605e7ffcc04b146321
https://doi.org/10.1101/239012