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1دورية أكاديمية
المؤلفون: Holly Koblish, Yun-Long Li, Niu Shin, Leslie Hall, Qian Wang, Kathy Wang, Maryanne Covington, Cindy Marando, Kevin Bowman, Jason Boer, Krista Burke, Richard Wynn, Alex Margulis, Gary W Reuther, Que T Lambert, Valerie Dostalik Roman, Ke Zhang, Hao Feng, Chu-Biao Xue, Sharon Diamond, Greg Hollis, Swamy Yeleswaram, Wenqing Yao, Reid Huber, Kris Vaddi, Peggy Scherle
المصدر: PLoS ONE, Vol 13, Iss 6, p e0199108 (2018)
وصف الملف: electronic resource
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المؤلفون: Phillip C.C. Liu, Peggy Scherle, Gregory Hollis, Reid Huber, Andrew P. Combs, Wenqing Yao, Chu-Biao Xue, Swamy Yeleswaram, Bruce Ruggeri, Richard Wynn, Maryanne Covington, Yanlong Li, Xin He, Christine Gardiner, Pramod Thekkat, Valerie Dostalik, Patricia Feldman, Darlise DiMatteo, Padmaja Polam, Nikoo Falahatpisheh, Robert Collins, Jun Li, Xuesong Mike Liu, Huiqing Liu, Ravi Jalluri, Margaret Favata, Paul Waeltz, Nina Zolotarjova, Alla Volgina, Xiaoming Wen, Mark Rupar, Sharon Diamond, Thomas Maduskuie, Richard Sparks, Timothy C. Burn, Matthew C. Stubbs
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a9cd1caeb5c5e06cfd8b05f86b576b1
https://doi.org/10.1158/1078-0432.22475952 -
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المؤلفون: Phillip C.C. Liu, Peggy Scherle, Gregory Hollis, Reid Huber, Andrew P. Combs, Wenqing Yao, Chu-Biao Xue, Swamy Yeleswaram, Bruce Ruggeri, Richard Wynn, Maryanne Covington, Yanlong Li, Xin He, Christine Gardiner, Pramod Thekkat, Valerie Dostalik, Patricia Feldman, Darlise DiMatteo, Padmaja Polam, Nikoo Falahatpisheh, Robert Collins, Jun Li, Xuesong Mike Liu, Huiqing Liu, Ravi Jalluri, Margaret Favata, Paul Waeltz, Nina Zolotarjova, Alla Volgina, Xiaoming Wen, Mark Rupar, Sharon Diamond, Thomas Maduskuie, Richard Sparks, Timothy C. Burn, Matthew C. Stubbs
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67622e0fbfefceb9ea9cf87738b999fe
https://doi.org/10.1158/1078-0432.c.6529230.v1 -
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المؤلفون: Reid Huber, Maryanne Covington, Xin He, Paul Waeltz, Valerie Dostalik, Yanlong Li, Nina Zolotarjova, Chu-Biao Xue, Matthew C. Stubbs, Jun Li, Huiqing Liu, Peggy Scherle, Timothy Burn, Sharon Diamond, Thomas Maduskuie, Wenqing Yao, Padmaja Polam, Richard B. Sparks, Christine Gardiner, Xuesong Mike Liu, Robert Collins, Nikoo Falahatpisheh, Andrew P. Combs, Phillip Liu, Margaret Favata, Gregory Hollis, Richard Wynn, Swamy Yeleswaram, Bruce Ruggeri, Alla Volgina, Ravi Kumar Jalluri, Pramod Thekkat, Darlise DiMatteo, Patricia Feldman, Mark Rupar, Xiaoming Wen
المصدر: Clinical Cancer Research. 25:300-311
مصطلحات موضوعية: STAT3 Transcription Factor, 0301 basic medicine, Cancer Research, BRD4, Cell Cycle Proteins, Fibroblast growth factor, Proto-Oncogene Proteins c-myc, BET inhibitor, Mice, 03 medical and health sciences, 0302 clinical medicine, In vivo, Cell Line, Tumor, Animals, Humans, Receptor, Fibroblast Growth Factor, Type 3, Organic Chemicals, STAT3, Receptor, Cell Proliferation, Janus Kinases, biology, Chemistry, Proteins, Histone-Lysine N-Methyltransferase, Receptors, Interleukin-6, Bromodomain, Gene Expression Regulation, Neoplastic, Repressor Proteins, 030104 developmental biology, Oncology, Fibroblast growth factor receptor, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Heterografts, Multiple Myeloma, Protein Binding, Signal Transduction, Transcription Factors
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd0f9e6b013bb2a593a4e013aa8feee1
https://doi.org/10.1158/1078-0432.ccr-18-0098 -
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المؤلفون: Swamy Yeleswaram, Thomas Maduskuie, Brian Wayland, Hao Feng, Patricia Feldman, Niu Shin, Yanlong Li, Chu-Biao Xue, Peggy Scherle, Song Mei, Kathy Wang, Maryanne Covington, Wenqing Yao, Padmaja Polam, Richard B. Sparks, Wenyu Zhu, Xin He, Sharon Diamond, Eddy W. Yue, Chunhong He, Brian Metcalf, Holly Koblish, Ke Zhang, Nikoo Falahatpisheh, Brent Douty, Leslie Hall, Yu Li, Andrew P. Combs, Joseph Glenn, Kamna Katiyar, Yun-Long Li
المصدر: ACS Med Chem Lett
مصطلحات موضوعية: Purine, Phosphoinositide 3-kinase, biology, 010405 organic chemistry, Organic Chemistry, Pharmacology, 01 natural sciences, Biochemistry, Duvelisib, Pyrazolopyrimidine, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry.chemical_compound, chemistry, Pharmacokinetics, In vivo, Drug Discovery, biology.protein, Idelalisib, ADME
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المؤلفون: Sharon Diamond, Taisheng Huang, Karen Gallagher, Jun Li, Brittany Fay, Monika Scuron, Michael Peel, Robert C. Newton, Niu Shin, Ashish Juvekar, Peggy Scherle, Xin He, Julian Oliver, Robert Collins, Chu-Biao Xue, Krista Burke, Yan Zhang, Paul Smith, Wenqing Yao, Maryanne Covington, Margaret Favata, Sarala Sarah
المصدر: European Journal of Pharmacology. 885:173505
مصطلحات موضوعية: STAT3 Transcription Factor, 0301 basic medicine, T-Lymphocytes, Primary Cell Culture, Graft vs Host Disease, Arthritis, Disease, Pharmacology, Inflammatory bowel disease, Pathogenesis, Mice, 03 medical and health sciences, 0302 clinical medicine, JAK1 Inhibitor, medicine, Animals, Humans, Lymphocytes, Colitis, STAT3, Chemokine CCL2, Inflammation, Mice, Inbred BALB C, Dose-Response Relationship, Drug, biology, business.industry, Janus Kinase 1, Inflammatory Bowel Diseases, medicine.disease, Arthritis, Experimental, Rats, STAT Transcription Factors, 030104 developmental biology, Rats, Inbred Lew, biology.protein, Azetidines, Isonicotinic Acids, business, Janus kinase, 030217 neurology & neurosurgery, Signal Transduction
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المؤلفون: Brian Metcalf, Sharon Diamond, Taisheng Huang, Lixin Shao, Swamy Yeleswaram, D. Joseph Rogier, Greg Hollis, Michael Xia, Ke Zhang, Ganfeng Cao, Nancy Contel, Lingquan Kong, Peggy Scherle, Maryanne Covington, Tom Emm, Robert Hughes, Joseph Glenn, Robert C. Newton, Kris Vaddi, Changsheng Zheng, Lou Storace, Chu-Biao Xue, Rajan Anand, Hao Feng, Meloni David, Anlai Wang, Mei Li, Philip A. Morton, Robinson Darius J, Qi Han, Rajesh V. Devraj, Yingxin Zhang
المصدر: ACS Medicinal Chemistry Letters. 2:913-918
مصطلحات موضوعية: CCR2, biology, business.industry, Organic Chemistry, High selectivity, hERG, Antagonist, Pharmacology, Biochemistry, In vitro, Bioavailability, In vivo, Drug Discovery, Ccr2 antagonist, biology.protein, Medicine, business
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المؤلفون: Brian Metcalf, Reid Huber, Wenqing Yao, Taisheng Huang, Peggy Scherle, Bruce Ruggeri, Matthew C. Stubbs, Chu-Biao Xue, Xiaoming Wen
المصدر: Cancer Research. 78:2938-2938
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, biology, business.industry, JAK-STAT signaling pathway, Cancer, medicine.disease, respiratory tract diseases, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Oncology, 030220 oncology & carcinogenesis, medicine, Cancer research, biology.protein, Osimertinib, Erlotinib, Epidermal growth factor receptor, Lung cancer, business, Protein kinase B, medicine.drug, EGFR inhibitors
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5b81610e89409924fcd340023e1c04a1
https://doi.org/10.1158/1538-7445.am2018-2938 -
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المؤلفون: Jun Li, Richard Wynn, Jennifer J. Harris, Yanlong Li, Patricia Feldman, Xiaozhao Wang, Holly Koblish, Yvonne Lo, Jonathan Rios-Doria, Ke Liu, Peggy Scherle, Xuesong M. Liu, Chu-Biao Xue, Maryanne B. Covington, Zhenhai Gao, Kerri Lasky, Min Ye, Wenqing Yao, Chunhong He, Margaret F. Favata, Christina Stevens, Robert Landman, Yu Li, Yun-Long Li, Hui Wang, Yaoyu Chen
المصدر: Cancer Research. 78:3759-3759
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Innate immune system, biology, Kinase, Chemistry, T cell, Transfection, Receptor tyrosine kinase, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Immune system, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, medicine, biology.protein, Cancer research, Kinase activity, TYRO3
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f7a779462e4043aa923c9c872ec3cff1
https://doi.org/10.1158/1538-7445.am2018-3759 -
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المؤلفون: Que T. Lambert, Kevin Bowman, Jason Boer, Gary W. Reuther, Valerie Roman, Peggy Scherle, Reid Huber, Krista Burke, Leslie Hall, Chu-Biao Xue, Kris Vaddi, Niu Shin, Yun-Long Li, Sharon Diamond, Alex Margulis, Qian Wang, Maryanne Covington, Greg Hollis, Swamy Yeleswaram, Holly Koblish, Hao Feng, Wenqing Yao, Cindy A. Marando, Richard Wynn, Ke Zhang, Kathy Wang
المصدر: PLoS ONE, Vol 13, Iss 6, p e0199108 (2018)
PLoS ONEمصطلحات موضوعية: Kinase Inhibitors, Cancer Treatment, lcsh:Medicine, Apoptosis, Biochemistry, Hematologic Cancers and Related Disorders, Mice, 0302 clinical medicine, Cell Signaling, hemic and lymphatic diseases, Medicine and Health Sciences, Protein phosphorylation, Enzyme Inhibitors, Post-Translational Modification, Phosphorylation, lcsh:Science, Multidisciplinary, Chemistry, Kinase, Cytarabine, Myeloid leukemia, Hematology, Isozymes, Enzymes, Leukemia, Myeloid, Acute, Leukemia, Oncology, Proto-Oncogene Proteins c-bcl-2, Hematologic Neoplasms, 030220 oncology & carcinogenesis, Network Analysis, Research Article, Signal Transduction, Computer and Information Sciences, Signal Inhibition, PIM1, Antineoplastic Agents, 03 medical and health sciences, Proto-Oncogene Proteins c-pim-1, Cell Line, Tumor, medicine, Animals, Humans, Protein Kinase Inhibitors, Protein kinase B, PI3K/AKT/mTOR pathway, Cell Proliferation, Dose-Response Relationship, Drug, lcsh:R, Biology and Life Sciences, Proteins, Cancers and Neoplasms, Cell Biology, medicine.disease, Signaling Networks, Enzymology, Cancer research, lcsh:Q, 030215 immunology