المؤلفون: Andrews LP; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Butler SC; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Cui J; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Cillo AR; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Cardello C; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Liu C; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Brunazzi EA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Baessler A; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Xie B; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Kunning SR; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Ngiow SF; Institute for Immunology and Immune Health, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Huang YJ; Institute for Immunology and Immune Health, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Manne S; Institute for Immunology and Immune Health, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Sharpe AH; Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Delgoffe GM; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Wherry EJ; Institute for Immunology and Immune Health, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Kirkwood JM; Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Bruno TC; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Workman CJ; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Vignali DAA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA. Electronic address: dvignali@pitt.edu.

المصدر: Cell [Cell] 2024 Aug 08; Vol. 187 (16), pp. 4355-4372.e22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

مواضيع طبية MeSH: Lymphocyte Activation Gene 3 Protein* , Programmed Cell Death 1 Receptor*/metabolism , CD8-Positive T-Lymphocytes*/immunology , CD8-Positive T-Lymphocytes*/metabolism , Interferon-gamma*/metabolism , Mice, Inbred C57BL* , Antigens, CD*/metabolism, Animals ; Mice ; Autocrine Communication ; Humans ; Melanoma/immunology ; Melanoma/drug therapy ; Female ; Cell Line, Tumor ; Melanoma, Experimental/immunology ; T-Cell Exhaustion

المؤلفون: Cillo AR; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA. Electronic address: arc85@pitt.edu., Cardello C; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Shan F; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Integrative Systems Biology (ISB) Graduate Program, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Karapetyan L; Department of Medicine, Division of Hematology/Oncology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Kunning S; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Sander C; Department of Medicine, Division of Hematology/Oncology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Rush E; Department of Medicine, Division of Hematology/Oncology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Karunamurthy A; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Massa RC; Department of Medicine, Division of Hematology/Oncology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Rohatgi A; Department of Medicine, Division of Hematology/Oncology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Workman CJ; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Kirkwood JM; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Department of Medicine, Division of Hematology/Oncology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA. Electronic address: kirkwoodjm@upmc.edu., Bruno TC; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA. Electronic address: tbruno@pitt.edu., Vignali DAA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA. Electronic address: dvignali@pitt.edu.

المصدر: Cell [Cell] 2024 Aug 08; Vol. 187 (16), pp. 4373-4388.e15.

نوع المنشور: Clinical Trial, Phase II; Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

مواضيع طبية MeSH: CD8-Positive T-Lymphocytes*/immunology , CD8-Positive T-Lymphocytes*/metabolism , Lymphocyte Activation Gene 3 Protein*/antagonists & inhibitors , Melanoma*/immunology , Melanoma*/drug therapy , Melanoma*/genetics , Programmed Cell Death 1 Receptor*/antagonists & inhibitors, Humans ; Antigens, CD/metabolism ; Antigens, CD/genetics ; Basic-Leucine Zipper Transcription Factors/metabolism ; Basic-Leucine Zipper Transcription Factors/genetics ; Cell Differentiation ; Cytotoxicity, Immunologic ; High Mobility Group Proteins ; Immune Checkpoint Inhibitors/therapeutic use ; Immune Checkpoint Inhibitors/pharmacology ; Nivolumab/therapeutic use ; Nivolumab/pharmacology ; Positive Regulatory Domain I-Binding Factor 1/metabolism ; Positive Regulatory Domain I-Binding Factor 1/genetics ; Signal Transduction

المؤلفون: Daley JD, Mukherjee E, Tufino AC, Bailey N, Bhaskar S, Periyapatna N, MacFawn I, Kunning S, Hinck C, Bruno T, Olson AC, McAllister-Lucas LM, Hinck AP, Cooper K, Bao R, Cillo AR, Bailey KM

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2024 May 10. Date of Electronic Publication: 2024 May 10.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Rao A, Zhang X, Cillo AR, Sussman JH, Sandlesh P, Tarbay AC, Mallela AN, Cardello C, Krueger K, Xu J, Li A, Xu J, Patterson J, Akca E, Angione A, Jaman E, Kim WJ, Allen J, Venketeswaran A, Zinn PO, Parise R, Beumer J, Duensing A, Holland EC, Ferris R, Bagley SJ, Bruno TC, Vignali DAA, Agnihotri S, Amankulor NM

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2024 Apr 13. Date of Electronic Publication: 2024 Apr 13.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Shan F; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Integrative Systems Biology Program, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Cillo AR; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Cardello C; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Yuan DY; Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Kunning SR; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Cui J; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Lampenfeld C; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Williams AM; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., McDonough AP; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Pennathur A; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Department of Cardiothoracic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Luketich JD; Department of Cardiothoracic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Kirkwood JM; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Department of Medicine, Division of Hematology/Oncology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Ferris RL; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Bruno TC; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Workman CJ; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Benos PV; Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Department of Epidemiology, University of Florida, Gainesville, FL, USA., Vignali DAA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.

المصدر: Science immunology [Sci Immunol] 2023 Sep 15; Vol. 8 (87), pp. eadf6717. Date of Electronic Publication: 2023 Sep 15.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101688624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2470-9468 (Electronic) Linking ISSN: 24709468 NLM ISO Abbreviation: Sci Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Basic-Leucine Zipper Transcription Factors*/genetics , Gene Regulatory Networks* , Head and Neck Neoplasms*/genetics, Humans ; Autoimmune Diseases ; Squamous Cell Carcinoma of Head and Neck/genetics ; T-Lymphocytes, Regulatory

المؤلفون: Onkar S; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Graduate Program in Microbiology and Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Cui J; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Zou J; Department of Biostatistics, University of Pittsburgh, Pittsburgh, PA, USA., Cardello C; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Cillo AR; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Uddin MR; Computational Biology Department, Carnegie Mellon University, Pittsburgh, PA, USA.; Joint Carnegie Mellon University-University of Pittsburgh PhD Program in Computational Biology, Pittsburgh, PA, USA., Sagan A; Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA, USA.; UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Joy M; UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; NSABP Foundation, Pittsburgh, PA, USA., Osmanbeyoglu HU; Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA., Pogue-Geile KL; NSABP Foundation, Pittsburgh, PA, USA., McAuliffe PF; Section of Breast Surgery, Division of Surgical Oncology, Department of Surgery, University of Pittsburgh College of Medicine, Magee Women's Hospital of UPMC, Pittsburgh, PA, USA.; Women's Cancer Research Center, UPMC Hillman Cancer Center, Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, PA, USA., Lucas PC; UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; NSABP Foundation, Pittsburgh, PA, USA.; Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA.; Cancer Biology Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Tseng GC; Department of Biostatistics, University of Pittsburgh, Pittsburgh, PA, USA., Lee AV; Women's Cancer Research Center, UPMC Hillman Cancer Center, Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, PA, USA.; Cancer Biology Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, USA., Bruno TC; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Oesterreich S; Women's Cancer Research Center, UPMC Hillman Cancer Center, Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, PA, USA. oesterreichs@upmc.edu.; Cancer Biology Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA. oesterreichs@upmc.edu.; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, USA. oesterreichs@upmc.edu., Vignali DAA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. dvignali@pitt.edu.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA. dvignali@pitt.edu.; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA. dvignali@pitt.edu.

المصدر: Nature cancer [Nat Cancer] 2023 Apr; Vol. 4 (4), pp. 582.

نوع المنشور: Published Erratum

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101761119 Publication Model: Print Cited Medium: Internet ISSN: 2662-1347 (Electronic) Linking ISSN: 26621347 NLM ISO Abbreviation: Nat Cancer Subsets: PubMed not MEDLINE; MEDLINE

المؤلفون: Onkar S; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Graduate Program in Microbiology and Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Cui J; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Zou J; Department of Biostatistics, University of Pittsburgh, Pittsburgh, PA, USA., Cardello C; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Cillo AR; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Uddin MR; Computational Biology Department, Carnegie Mellon University, Pittsburgh, PA, USA.; Joint Carnegie Mellon University-University of Pittsburgh PhD Program in Computational Biology, Pittsburgh, PA, USA., Sagan A; Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA, USA.; UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Joy M; UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; NSABP Foundation, Pittsburgh, PA, USA., Osmanbeyoglu HU; Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA., Pogue-Geile KL; NSABP Foundation, Pittsburgh, PA, USA., McAuliffe PF; Section of Breast Surgery, Division of Surgical Oncology, Department of Surgery, University of Pittsburgh College of Medicine, Magee Women's Hospital of UPMC, Pittsburgh, PA, USA.; Women's Cancer Research Center, UPMC Hillman Cancer Center, Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, PA, USA., Lucas PC; UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; NSABP Foundation, Pittsburgh, PA, USA.; Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA.; Cancer Biology Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Tseng GC; Department of Biostatistics, University of Pittsburgh, Pittsburgh, PA, USA., Lee AV; Women's Cancer Research Center, UPMC Hillman Cancer Center, Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, PA, USA.; Cancer Biology Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, USA., Bruno TC; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Oesterreich S; Women's Cancer Research Center, UPMC Hillman Cancer Center, Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, PA, USA. oesterreichs@upmc.edu.; Cancer Biology Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA. oesterreichs@upmc.edu.; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, USA. oesterreichs@upmc.edu., Vignali DAA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. dvignali@pitt.edu.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA. dvignali@pitt.edu.; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA. dvignali@pitt.edu.

المصدر: Nature cancer [Nat Cancer] 2023 Apr; Vol. 4 (4), pp. 516-534. Date of Electronic Publication: 2023 Mar 16.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101761119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-1347 (Electronic) Linking ISSN: 26621347 NLM ISO Abbreviation: Nat Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Lobular*/drug therapy , Breast Neoplasms*/drug therapy , Carcinoma, Ductal, Breast*/drug therapy, Female ; Humans ; Treatment Outcome ; Disease-Free Survival ; Tumor Microenvironment

المؤلفون: Andrews LP; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania., Cillo AR; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania., Karapetyan L; Division of Hematology and Oncology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Kirkwood JM; Division of Hematology and Oncology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania., Workman CJ; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania., Vignali DAA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania.; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania.

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2022 Dec 01; Vol. 28 (23), pp. 5030-5039.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Melanoma*/drug therapy , Melanoma*/genetics , Programmed Cell Death 1 Receptor*, Humans ; Antigens, CD/metabolism ; CD8-Positive T-Lymphocytes ; Immunotherapy/methods ; Clinical Trials, Phase III as Topic

المؤلفون: Cillo AR; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania., Mukherjee E; Department of Pediatrics, Division of Pediatric Hematology and Oncology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Bailey NG; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Onkar S; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania.; Program in Microbiology and Immunology, Pittsburgh, Pennsylvania., Daley J; Department of Pediatrics, Division of Pediatric Hematology and Oncology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Salgado C; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Li X; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.; School of Medicine, Tsinghua University, Beijing, China., Liu D; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.; School of Medicine, Tsinghua University, Beijing, China., Ranganathan S; Division of Pathology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Burgess M; Department of Medicine, Division of Hematology/Oncology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Sembrat J; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania., Weiss K; Department of Orthopedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Watters R; Department of Orthopedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Bruno TC; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania.; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania., Vignali DAA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania.; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania., Bailey KM; Department of Pediatrics, Division of Pediatric Hematology and Oncology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania.

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2022 Nov 14; Vol. 28 (22), pp. 4968-4982.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Sarcoma, Ewing*/pathology , Osteosarcoma*/drug therapy , Bone Neoplasms*/pathology , Sarcoma*, Adolescent ; Humans ; Neoplasm Recurrence, Local ; Cell Communication

المؤلفون: Wang W; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA., Wu S; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA., Cen Z; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA; School of Medicine, Tsinghua University, Beijing, China., Zhang Y; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA., Chen Y; Center for Pharmacogenetics, Department of Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy, Pittsburgh, PA 15261, USA., Huang Y; Center for Pharmacogenetics, Department of Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy, Pittsburgh, PA 15261, USA., Cillo AR; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA., Prokopec JS; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA., Quarato G; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Vignali DAA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, 5115 Center Avenue, Pittsburgh, PA 15213, USA., Stewart-Ornstein J; Department of Computational and Systems Biology, Hillman Cancer Center and University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA., Li S; Center for Pharmacogenetics, Department of Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy, Pittsburgh, PA 15261, USA., Lu B; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, 5115 Center Avenue, Pittsburgh, PA 15213, USA. Electronic address: binfeng@pitt.edu., Gong YN; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, 5115 Center Avenue, Pittsburgh, PA 15213, USA. Electronic address: yngong@pitt.edu.

المصدر: Cell reports [Cell Rep] 2022 Nov 01; Vol. 41 (5), pp. 111582.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Phosphatidylserines*/metabolism , Neoplasms*/therapy , Neoplasms*/metabolism, Humans ; Phospholipids/metabolism ; Cell Membrane/metabolism ; Apoptosis/physiology ; Immunotherapy