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المؤلفون: Arthur Bergman, Kristin Chidsey, Aditi R. Saxena, Ryan M. Esquejo, Donal Gorman, Albert M. Kim, David A. Griffith, Clare Buckeridge
المصدر: Nature Medicine. 27:1079-1087
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, business.industry, General Medicine, Type 2 diabetes, Placebo, medicine.disease, General Biochemistry, Genetics and Molecular Biology, law.invention, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Blood pressure, Tolerability, Randomized controlled trial, law, 030220 oncology & carcinogenesis, Diabetes mellitus, Internal medicine, Medicine, Adverse effect, business, Glycemic
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المؤلفون: David A. Griffith, David J. Edmonds, Jean-Philippe Fortin, Amit S. Kalgutkar, J. Brent Kuzmiski, Paula M. Loria, Aditi R. Saxena, Scott W. Bagley, Clare Buckeridge, John M. Curto, David R. Derksen, João M. Dias, Matthew C. Griffor, Seungil Han, V. Margaret Jackson, Margaret S. Landis, Daniel Lettiere, Chris Limberakis, Yuhang Liu, Alan M. Mathiowetz, Jayesh C. Patel, David W. Piotrowski, David A. Price, Roger B. Ruggeri, David A. Tess
المصدر: Journal of medicinal chemistry. 65(12)
مصطلحات موضوعية: Drug Discovery, Molecular Medicine, Animals, Humans, Hypoglycemic Agents, Peptides, Glucagon-Like Peptide-1 Receptor
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المؤلفون: Jeffrey Crawford, Roberto A. Calle, Susie M. Collins, Yan Weng, Shannon L. Lubaczewski, Clare Buckeridge, Ellen Q. Wang, Magdalena A. Harrington, Anil Tarachandani, Michelle I. Rossulek, James H. Revkin
المصدر: Cancer Research. 83:CT108-CT108
مصطلحات موضوعية: Cancer Research, Oncology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c7627f3e336a7d3fba4a14a9268c117c
https://doi.org/10.1158/1538-7445.am2023-ct108 -
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المؤلفون: David A. Beebe, Gregg D. Cappon, Michelle Clasquin, Marc K. Hellerstein, Norimitsu Shirai, William J. Reagan, Zhongyuan Sun, Katherine Hales, Gabriele E. Sonnenberg, Jeffrey A. Pfefferkorn, Theodore J. Schmahai, Nicholas B. Vera, Marcy Matthews, Trenton T. Ross, Clare Buckeridge, Enida Ziso Qejvanaj, Kenneth L. Kelly, Shoh Asano, Santos Carvajal-Gonzalez, William P. Esler, Paul A. Amor, Kelvin W. Li, Arthur Bergman
المصدر: Nature Metabolism. 2:1163-1178
مصطلحات موضوعية: Blood Platelets, Endocrinology, Diabetes and Metabolism, Gene Expression, Pharmacology, Biology, Dogs, Double-Blind Method, Megakaryocyte, Physiology (medical), Internal Medicine, medicine, Animals, Humans, Platelet, Enzyme Inhibitors, Dose-Response Relationship, Drug, Platelet Count, Lipogenesis, Lipid metabolism, Cell Biology, Metabolism, Lipid Metabolism, Rats, Pyruvate carboxylase, Macaca fascicularis, Dose–response relationship, medicine.anatomical_structure, Diabetes Mellitus, Type 2, Megakaryocytes, Ex vivo, Acetyl-CoA Carboxylase
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المؤلفون: Aditi R, Saxena, Donal N, Gorman, Ryan M, Esquejo, Arthur, Bergman, Kristin, Chidsey, Clare, Buckeridge, David A, Griffith, Albert M, Kim
المصدر: Nature medicine. 27(6)
مصطلحات موضوعية: Blood Glucose, Male, Mice, Diabetes Mellitus, Type 2, Body Weight, Animals, Humans, Hypoglycemic Agents, Female, Obesity, Middle Aged, Glucagon-Like Peptide-1 Receptor, Metformin
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المؤلفون: J. Brent Kuzmiski, João M. Dias, Seungil Han, Chris Limberakis, David Price, David J. Edmonds, John M. Curto, Amit S. Kalgutkar, Daniel J. Lettiere, David A. Tess, Clare Buckeridge, Matthew C. Griffor, David R. Derksen, Alan M. Mathiowetz, Roger B. Ruggeri, Paula M. Loria, Aditi R. Saxena, Scott W. Bagley, Yuhang Liu, Margaret S. Landis, David W. Piotrowski, V. Margaret Jackson, David A. Griffith, Jean-Phillipe Fortin
مصطلحات موضوعية: chemistry.chemical_classification, Agonist, Chemistry, medicine.drug_class, Insulin, medicine.medical_treatment, Endogeny, Peptide, Pharmacology, Small molecule, Glucagon-like peptide-1, Oral administration, medicine, Receptor
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::064b771366df377937229b83ffb7a9bf
https://doi.org/10.1101/2020.09.29.319483 -
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المؤلفون: Donal Gorman, Clare Buckeridge, Kristin Chidsey, Aditi R. Saxena, Arthur Bergman, Albert M. Kim
المصدر: Diabetes. 69
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, business.industry, Nausea, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, Placebo, Metformin, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Pharmacokinetics, Tolerability, Internal medicine, Internal Medicine, medicine, Vomiting, Dosing, medicine.symptom, business, Adverse effect, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0f605db53db10d89045aa5f55a3312b3
https://doi.org/10.2337/db20-353-or -
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المؤلفون: Jeffrey A. Pfefferkorn, Matthew Gorgoglione, Scott M. Turner, Clare Buckeridge, Nicholas B. Vera, Marc K. Hellerstein, Annette M. Silvia, Gabriele E. Sonnenberg, Santos Carvajal-Gonzalez, Kathleen Biddle, Paul A. Amor, Raja K Sivamani, Lauren A Hassoun, David A. Griffith, Carine Beysen, Steven M. Watkins, Timothy P. Rolph, Julie Purkal, Mark Fitch, Gregory J. Tesz, William P. Esler, Frank J. Geoly, Suzana S. Bosanac
المصدر: Science translational medicine. 11(492)
مصطلحات موضوعية: 0301 basic medicine, Sebaceous gland, Adult, Male, medicine.medical_specialty, Adolescent, Swine, Human skin, 03 medical and health sciences, chemistry.chemical_compound, Squalene, Sebaceous Glands, Young Adult, 0302 clinical medicine, Internal medicine, Cricetinae, Acne Vulgaris, medicine, Animals, Humans, Enzyme Inhibitors, Rats, Wistar, Acne, Cells, Cultured, Triglycerides, integumentary system, Triglyceride, Cholesterol, Lipogenesis, Acetyl-CoA carboxylase, General Medicine, Middle Aged, medicine.disease, Malonyl Coenzyme A, Sebum, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, chemistry, 030220 oncology & carcinogenesis, Swine, Miniature, Female, Acetyl-CoA Carboxylase
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed755d8f32090787a27b2b7eaeec5c2b
https://pubmed.ncbi.nlm.nih.gov/31092695 -
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المؤلفون: Ping He, Clare Buckeridge, Ekaterina Tankisheva, Martin M. Bednar, Robert Alexander, Christine Alvey, Ruolun Qiu, Danny Chen, Richann Liu, Anne-Marie Wills
المصدر: Alzheimer's & Dementia. 13
مصطلحات موضوعية: 0301 basic medicine, Epidemiology, Health Policy, Safety tolerability, Pharmacology, medicine.disease, 03 medical and health sciences, Psychiatry and Mental health, Cellular and Molecular Neuroscience, 030104 developmental biology, 0302 clinical medicine, Developmental Neuroscience, Tolerability, Pharmacokinetics, Diabetes mellitus, Pharmacodynamics, medicine, Neurology (clinical), Geriatrics and Gerontology, 030217 neurology & neurosurgery