نتائج البحث - "Clare L Killick-Cole"

المصدر: The Journal of Pathology
Haynes, H R, Scott, H L, Killick-Cole, C L, Shaw, G, Brend, T, Hares, K M, Redondo, J, Kemp, K C, Ballesteros, L S, Herman, A, Cordero-Llana, O, Singleton, W G, Mills, F, Batstone, T, Bulstrode, H, Kauppinen, R A, Wurdak, H, Uney, J B, Short, S C, Wilkins, A & Kurian, K M 2019, ' shRNA-mediated PPARα knockdown in human glioma stem cells reduces in vitro proliferation and inhibits orthotopic xenograft tumour growth ', Journal of Pathology, vol. 247, no. 4, pp. 422-434 . https://doi.org/10.1002/path.5201

مصطلحات موضوعية: 0301 basic medicine, endocrine system, glioma stem cell, Transplantation, Heterologous, Down-Regulation, Mice, SCID, Biology, Brain and Behaviour, PPARα, Pathology and Forensic Medicine, Small hairpin RNA, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, SOX2, shRNA, Mice, Inbred NOD, Glioma, medicine, Biomarkers, Tumor, Tumor Cells, Cultured, Animals, Humans, PPAR alpha, RNA, Small Interfering, Gene knockdown, Original Paper, Brain Neoplasms, Lentivirus, medicine.disease, Original Papers, Neural stem cell, Transplantation, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Cell Transformation, Neoplastic, Phenotype, 030220 oncology & carcinogenesis, Gene Knockdown Techniques, embryonic structures, Cancer research, Neoplastic Stem Cells, Female, Stem cell, Glioblastoma, Signal Transduction

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URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e39bf5d26efe7fd0d11f188b4b54bded
http://europepmc.org/articles/PMC6462812

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SCIDOT-36. PREDICTIVE CED INFUSION VOLUMES FOR SURGICAL PLANNING AND INFUSION REGIME STRATEGIES

المؤلفون: David Johnson, Steven S Gill, Paul Skinner, Owen Lewis, Clare L Killick-Cole, Max Woolley, Alison Bienemann

المصدر: Neuro Oncol

مصطلحات موضوعية: Cancer Research, Neurologic Oncology, business.industry, Blood–brain barrier, Surgical planning, medicine.anatomical_structure, Oncology, Infusion Procedure, Anesthesia, Abstracts from the 3rd Sno-Scidot Joint Conference on Therapeutic Delivery to the CNS, Tissue damage, Medicine, In vitro study, Neurology (clinical), business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b9263642428afa83120204b00698026
https://europepmc.org/articles/PMC6846196/

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The transcription factor PPARα is overexpressed and is associated with a favourable prognosis in IDH-wildtype primary glioblastoma

المؤلفون: Krishnakumar Garadi, Clare L Killick-Cole, Alastair Wilkins, Juliana Redondo, Paul D. White, Harry R Haynes, Sam Guglani, Kelly M Hares, Kathreena M Kurian, Kevin C Kemp, William G B Singleton, Jonathan R Stevens

المصدر: Histopathology. 70:1030-1043

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b4375b68b222c536f8de2a3519bb163
https://doi.org/10.1111/his.13142

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Combined use of CDK4/6 and mTOR inhibitors induce synergistic growth arrest of diffuse intrinsic pontine glioma cells via mutual downregulation of mTORC1 activity

المؤلفون: Neil U Barua, Lisa J. Boulter, Steven S Gill, Daniel J. Asby, Alison Bienemann, Claire Asby, Marcella J Wyatt, Clare L Killick-Cole, William G B Singleton

المصدر: Asby, D, Killick-Cole, C, Boulter, L, Singleton, W, Asby, C, Wyatt, M, Barua, N, Bienemann, A & Gill, S 2018, ' Combined use of CDK4/6 and mTOR inhibitors induce synergistic growth arrest of diffuse intrinsic pontine glioma cells via mutual downregulation of mTORC1 activity ', Cancer Management and Research, vol. 10, pp. 3483-3500 . https://doi.org/10.2147/CMAR.S167095

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URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fdb65448a5314dd7979fcf12de3c849
https://www.dovepress.com/combined-use-of-cdk46-and-mtor-inhibitors-induce-synergistic-growth-ar-peer-reviewed-article-CMAR

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SCIDOT-35. A NOVEL MODEL FOR THE OPTIMIZATION OF DRUG-DEVICE COMBINATIONS FOR THE TREATMENT OF BRAIN TUMORS

المؤلفون: Owen Lewis, Clare L Killick-Cole, Steven S Gill, Max Woolley, Alison Bienemann, David Johnson, Patrick Moore, Paul Skinner, Julia Fletcher

المصدر: Neuro Oncol

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e67596c2ff2edda99e4d33486402b64
https://doi.org/10.1093/neuonc/noz175.1171

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Evaluation of the quality of RNA extracted from archival FFPE glioblastoma and epilepsy surgical samples for gene expression assays

المؤلفون: Juliana Redondo, Karwan A. Moutasim, Clare L Killick-Cole, Kathreena M Kurian, Kevin C Kemp, Alastair Wilkins, Harry R Haynes, Kelly M Hares, Claire Faulkner

المصدر: Haynes, H R, Killick-Cole, C L, Hares, K M, Redondo, J, Kemp, K C, Moutasim, K A, Faulkner, C, Wilkins, A & Kurian, K M 2018, ' Evaluation of the quality of RNA extracted from archival FFPE glioblastoma and epilepsy surgical samples for gene expression assays ', Journal of Clinical Pathology, vol. 71, no. 8, pp. 695-701 . https://doi.org/10.1136/jclinpath-2017-204969

مصطلحات موضوعية: 0301 basic medicine, Quality Control, Time Factors, Tissue Fixation, RNA Stability, RNA integrity number, Biology, Pathology and Forensic Medicine, 03 medical and health sciences, Fixatives, 0302 clinical medicine, molecular pathology, Predictive Value of Tests, Reference genes, Formaldehyde, Gene expression, Humans, RNA, Neoplasm, Fragmentation (cell biology), Paraffin Embedding, Molecular pathology, Brain Neoplasms, brain tumours, Gene Expression Profiling, RNA, Reproducibility of Results, General Medicine, Molecular biology, 030104 developmental biology, PCR, Epilepsy, Temporal Lobe, 030220 oncology & carcinogenesis, Case-Control Studies, Nucleic acid, RNA extraction, Glioblastoma