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المؤلفون: Martin Pass, Donald Ogilvie, Richard Luke, Rebecca Watson, Clare Lane, James Yates, Ken Page, Christine C. Chresta, Sabina Cosulich, Darren Cross, Sally-Ann Ricketts, Juliana Maynard, Qunsheng Ji, Beirong Gao, Jing Li, Jingchuan Zhang, De-Hua Yu, Claire Crafter, Phillippa Dudley, Hannah Greenwood, Barry R. Davies
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db9ea91e81a67f3f040a1bb9626f1a13
https://doi.org/10.1158/1535-7163.22498635 -
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المؤلفون: Martin Pass, Donald Ogilvie, Richard Luke, Rebecca Watson, Clare Lane, James Yates, Ken Page, Christine C. Chresta, Sabina Cosulich, Darren Cross, Sally-Ann Ricketts, Juliana Maynard, Qunsheng Ji, Beirong Gao, Jing Li, Jingchuan Zhang, De-Hua Yu, Claire Crafter, Phillippa Dudley, Hannah Greenwood, Barry R. Davies
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26adbc826f9cc85329a52ca84cf29cd2
https://doi.org/10.1158/1535-7163.22498644.v1 -
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المؤلفون: Martin Pass, Donald Ogilvie, Richard Luke, Rebecca Watson, Clare Lane, James Yates, Ken Page, Christine C. Chresta, Sabina Cosulich, Darren Cross, Sally-Ann Ricketts, Juliana Maynard, Qunsheng Ji, Beirong Gao, Jing Li, Jingchuan Zhang, De-Hua Yu, Claire Crafter, Phillippa Dudley, Hannah Greenwood, Barry R. Davies
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58aca16ca8976daf5767839bc44394ac
https://doi.org/10.1158/1535-7163.22498647 -
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المؤلفون: Martin Pass, Donald Ogilvie, Richard Luke, Rebecca Watson, Clare Lane, James Yates, Ken Page, Christine C. Chresta, Sabina Cosulich, Darren Cross, Sally-Ann Ricketts, Juliana Maynard, Qunsheng Ji, Beirong Gao, Jing Li, Jingchuan Zhang, De-Hua Yu, Claire Crafter, Phillippa Dudley, Hannah Greenwood, Barry R. Davies
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f3112b5ae732cb14b1fb9210be4bf92
https://doi.org/10.1158/1535-7163.22498638.v1 -
5
المؤلفون: Martin Pass, Donald Ogilvie, Richard Luke, Rebecca Watson, Clare Lane, James Yates, Ken Page, Christine C. Chresta, Sabina Cosulich, Darren Cross, Sally-Ann Ricketts, Juliana Maynard, Qunsheng Ji, Beirong Gao, Jing Li, Jingchuan Zhang, De-Hua Yu, Claire Crafter, Phillippa Dudley, Hannah Greenwood, Barry R. Davies
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59eda9af138e0854ae982cf0930bd6d1
https://doi.org/10.1158/1535-7163.22498641 -
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المؤلفون: Martin Pass, Donald Ogilvie, Richard Luke, Rebecca Watson, Clare Lane, James Yates, Ken Page, Christine C. Chresta, Sabina Cosulich, Darren Cross, Sally-Ann Ricketts, Juliana Maynard, Qunsheng Ji, Beirong Gao, Jing Li, Jingchuan Zhang, De-Hua Yu, Claire Crafter, Phillippa Dudley, Hannah Greenwood, Barry R. Davies
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0694b929ca9bbf6674a0e14b9be57b20
https://doi.org/10.1158/1535-7163.22498650.v1 -
7
المؤلفون: Martin Pass, Donald Ogilvie, Richard Luke, Rebecca Watson, Clare Lane, James Yates, Ken Page, Christine C. Chresta, Sabina Cosulich, Darren Cross, Sally-Ann Ricketts, Juliana Maynard, Qunsheng Ji, Beirong Gao, Jing Li, Jingchuan Zhang, De-Hua Yu, Claire Crafter, Phillippa Dudley, Hannah Greenwood, Barry R. Davies
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48cc27e4c5c098c582d92d81ddb5859a
https://doi.org/10.1158/1535-7163.c.6535935 -
8
المؤلفون: Clare Lane, Nicola Colclough, Les A. Dakin, M. Raymond V. Finlay, Claudio Chuaqui, Mark J. Anderton, Christopher G. Chorley, Matthew Grist, Darren Cross, Richard A. Ward, Michael J. Waring, Teresa Klinowska, Jonathon P. Orme, Cath Eberlein, Judit E. Debreczeni, Scott W. Martin, Matthew R. Box, Peter D. Smith, Susan Ashton, Paul A. Bethel, Fengjiang Wang, Sam Butterworth, George B. Hill
المصدر: Journal of Medicinal Chemistry. 56:7025-7048
مصطلحات موضوعية: Models, Molecular, biology, Chemistry, Mutant, ErbB Receptors, Structure-Activity Relationship, Gefitinib, Biochemistry, Mutation, Drug Discovery, medicine, biology.protein, Molecular Medicine, Structure–activity relationship, Erlotinib, Epidermal growth factor receptor, Binding site, Tyrosine kinase, medicine.drug, Cysteine
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المؤلفون: Morris Jeffrey James, Gordon S. Currie, Jason Grant Kettle, Claire Crafter, Clare Lane, Ken Page, Peter Ballard, Linette Ruston, Hannah Dry, Martin Pass, Andrew G. Leach, Ryan Greenwood, Matt Addie, Judit E. Debreczeni, Johnson Paul David, Barry R. Davies, Gillian M. Lamont, Donald J. Ogilvie, David Buttar, Philippa Dudley, Richard W. A. Luke, Stuart E. Pearson
المصدر: Journal of Medicinal Chemistry. 56:2059-2073
مصطلحات موضوعية: Models, Molecular, medicine.drug_class, hERG, Administration, Oral, Carboxamide, Pharmacology, Inhibitory Concentration 50, Structure-Activity Relationship, In vivo, Cell Line, Tumor, Drug Discovery, medicine, Humans, Structure–activity relationship, Pyrroles, Protein Kinase Inhibitors, Protein kinase B, biology, Chemistry, Kinase, Xenograft Model Antitumor Assays, Pyrimidines, Biochemistry, biology.protein, Molecular Medicine, Phosphorylation, Female, Proto-Oncogene Proteins c-akt, Drug metabolism
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المؤلفون: Hannah Greenwood, Jingchuan Zhang, Jing Li, Rebecca Watson, Juliana Maynard, James W.T. Yates, Claire Crafter, Beirong Gao, Sally-Ann Ricketts, Darren Cross, Martin Pass, Clare Lane, Christine M. Chresta, Barry R. Davies, Sabina Cosulich, Ken M Page, Philippa Dudley, Qunsheng Ji, Richard W. A. Luke, De-Hua Yu, Donald J. Ogilvie
المصدر: Molecular Cancer Therapeutics. 11:873-887
مصطلحات موضوعية: Male, Cancer Research, Mice, Nude, Breast Neoplasms, Mice, SCID, Pharmacology, Lapatinib, Mice, chemistry.chemical_compound, Trastuzumab, Cell Line, Tumor, medicine, Animals, Humans, Potency, PTEN, Pyrroles, Protein kinase B, Cell Proliferation, biology, Akt inhibitor AZD5363, Prostatic Neoplasms, Xenograft Model Antitumor Assays, Pyrimidines, Oncology, chemistry, Docetaxel, biology.protein, Female, Growth inhibition, Proto-Oncogene Proteins c-akt, Signal Transduction, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e98875526525d3b19c1c9f1c3c90aab9
https://doi.org/10.1158/1535-7163.mct-11-0824-t