المؤلفون: Bastard, Paul, Zhang, Qian, Cobat, Aurélie, Jouanguy, Emmanuelle, Zhang, Shen-Ying, Abel, Laurent, Casanova, Jean-Laurent

المصدر: Comptes Rendus Biologies, Vol 344, Iss 1, Pp 19-25 (2021)

مصطلحات موضوعية: Life-threatening COVID-19, Pneumonia, Type I interferons, Inborn errors of immunity, Autoantibodies, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://comptes-rendus.academie-sciences.fr/biologies/articles/10.5802/crbiol.36/; https://doaj.org/toc/1768-3238

URL الوصول: https://doaj.org/article/54139b44ecd4477da8f5660c9a09e8f0

المؤلفون: Chan, Yi-Hao, Lundberg, Vanja, Le Pen, Jérémie, Yuan, Jiayi, Lee, Danyel, Pinci, Francesca, Volpi, Stefano, Nakajima, Koji, Bondet, Vincent, Åkesson, Sanna, Khobrekar, Noopur, Bodansky, Aaron, Du, Likun, Melander, Tina, Mariaggi, Alice-Andrée, Seeleuthner, Yoann, Saleh, Tariq, Chakravarty, Debanjana, Marits, Per, Dobbs, Kerry, Vonlanthen, Sofie, Hennings, Viktoria, Thörn, Karolina, Rinchai, Darawan, Bizien, Lucy, Chaldebas, Matthieu, Sobh, Ali, Özçelik, Tayfun, Keles, Sevgi, AlKhater, Suzan, Prando, Carolina, Meyts, Isabelle, Wilson, Michael, Rosain, Jérémie, Jouanguy, Emmanuelle, Aubart, Mélodie, Abel, Laurent, Mogensen, Trine, Pan-Hammarström, Qiang, Gao, Daxing, Duffy, Darragh, Cobat, Aurélie, Berg, Stefan, Notarangelo, Luigi, Harschnitz, Oliver, Rice, Charles, Studer, Lorenz, Casanova, Jean-Laurent, Ekwall, Olov, Zhang, Shen-Ying

المصدر: Journal of Experimental Medicine. 221(9)

مصطلحات موضوعية: Humans, Male, SARS-CoV-2, COVID-19, Brain Stem, Adolescent, Neurons, Encephalitis, Viral, Fibroblasts, Rhombencephalon

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/3j5022c2
https://escholarship.org/content/qt3j5022c2/qt3j5022c2.pdf

المؤلفون: Chan, Yi-Hao^{Aff1, IDs4158602407745x_cor1}, Liu, Zhiyong, Bastard, Paul^{Aff1, Aff2, Aff3, Aff4}, Khobrekar, Noopur, Hutchison, Kennen M., Yamazaki, Yasuhiro, Fan, Qing, Matuozzo, Daniela^{Aff2, Aff4}, Harschnitz, Oliver^{Aff5, Aff8}, Kerrouche, Nacim, Nakajima, Koji^{Aff1, Aff2, Aff4}, Amin, Param, Yatim, Ahmad, Rinchai, Darawan, Chen, Jie, Zhang, Peng, Ciceri, Gabriele, Chen, Jia, Dobbs, Kerry, Belkaya, Serkan^{Aff1, Aff9}, Lee, Danyel^{Aff1, Aff2, Aff4}, Gervais, Adrian^{Aff1, Aff2, Aff4}, Aydın, Kürşad, Kartal, Ayse, Hasek, Mary L., Zhao, Shuxiang, Reino, Eduardo Garcia, Lee, Yoon Seung, Seeleuthner, Yoann^{Aff2, Aff4}, Chaldebas, Matthieu, Bailey, Rasheed, Vanhulle, Catherine, Lorenzo, Lazaro^{Aff2, Aff4}, Boucherit, Soraya^{Aff2, Aff4}, Rozenberg, Flore, Marr, Nico, Mogensen, Trine H.^{Aff15, Aff16, Aff17}, Aubart, Mélodie^{Aff2, Aff4, Aff18}, Cobat, Aurélie^{Aff1, Aff2, Aff4}, Dulac, Olivier, Emiroglu, Melike, Paludan, Søren R.^{Aff15, Aff17, Aff21}, Abel, Laurent^{Aff1, Aff2, Aff4}, Notarangelo, Luigi, Longnecker, Richard, Smith, Greg, Studer, Lorenz, Casanova, Jean-Laurent^{Aff1, Aff2, Aff3, Aff4, Aff22, IDs4158602407745x_cor48}, Zhang, Shen-Ying^{Aff1, Aff2, Aff4, IDs4158602407745x_cor49}

المصدر: Nature: International weekly journal of science. 632(8024):390-400

المؤلفون: Yu, David, Miller, Corey, Feng, Yi, Guichard, Audrey, Béziat, Vivien, Bustamante, Jacinta, Pan-Hammarström, Qiang, Zhang, Yu, Rosen, Lindsey, Holland, Steve, Bosticardo, Marita, Kenney, Heather, Castagnoli, Riccardo, Slade, Charlotte, Boztuğ, Kaan, Mahlaoui, Nizar, Latour, Sylvain, Abraham, Roshini, Lougaris, Vassilios, Hauck, Fabian, Sediva, Anna, Atschekzei, Faranaz, Sogkas, Georgios, Poli, M, Slatter, Mary, Palterer, Boaz, Keller, Michael, Pinzon-Charry, Alberto, Sullivan, Anna, Droney, Luke, Suan, Daniel, Wong, Melanie, Kane, Alisa, Hu, Hannah, Ma, Cindy, Grombiříková, Hana, Ciznar, Peter, Dalal, Ilan, Aladjidi, Nathalie, Hie, Miguel, Lazaro, Estibaliz, Franco, Jose, Keles, Sevgi, Malphettes, Marion, Pasquet, Marlene, Maccari, Maria, Meinhardt, Andrea, Ikinciogullari, Aydan, Shahrooei, Mohammad, Celmeli, Fatih, Frosk, Patrick, Goodnow, Christopher, Gray, Paul, Belot, Alexandre, Kuehn, Hye, Rosenzweig, Sergio, Miyara, Makoto, Licciardi, Francesco, Servettaz, Amélie, Barlogis, Vincent, Le Guenno, Guillaume, Herrmann, Vera-Maria, Kuijpers, Taco, Ducoux, Grégoire, Sarrot-Reynauld, Françoise, Schuetz, Catharina, Cunningham-Rundles, Charlotte, Rieux-Laucat, Frédéric, Tangye, Stuart, Sobacchi, Cristina, Doffinger, Rainer, Warnatz, Klaus, Grimbacher, Bodo, Fieschi, Claire, Berteloot, Laureline, Bryant, Vanessa, Trouillet Assant, Sophie, Su, Helen, Neven, Benedicte, Abel, Laurent, Zhang, Qian, Boisson, Bertrand, Cobat, Aurélie, Jouanguy, Emmanuelle, Kampe, Olle, Bastard, Paul, Roifman, Chaim, Landegren, Nils, Notarangelo, Luigi, Le Voyer, Tom, Parent, Audrey, Liu, Xian, Cederholm, Axel, Gervais, Adrian, Rosain, Jérémie, Nguyen, Tina, Perez Lorenzo, Malena, Rackaityte, Elze, Rinchai, Darawan, Zhang, Peng

المصدر: Nature. 623(7988)

مصطلحات موضوعية: Humans, Autoantibodies, COVID-19, Gain of Function Mutation, Genetic Predisposition to Disease, Heterozygote, I-kappa B Proteins, Interferon Type I, Loss of Function Mutation, NF-kappa B, NF-kappa B p52 Subunit, Pneumonia, Viral, Thymus Gland, Thyroid Epithelial Cells

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6w33j3wh

المؤلفون: Matuozzo, Daniela^{Aff1, Aff2}, Talouarn, Estelle^{Aff1, Aff2}, Marchal, Astrid^{Aff1, Aff2}, Zhang, Peng, Manry, Jeremy^{Aff1, Aff2}, Seeleuthner, Yoann^{Aff1, Aff2}, Zhang, Yu, Bolze, Alexandre, Chaldebas, Matthieu, Milisavljevic, Baptiste, Gervais, Adrian^{Aff1, Aff2}, Bastard, Paul^{Aff1, Aff2, Aff3}, Asano, Takaki, Bizien, Lucy^{Aff1, Aff2}, Barzaghi, Federica, Abolhassani, Hassan^{Aff7, Aff8}, Tayoun, Ahmad Abou^{Aff9, Aff10}, Aiuti, Alessandro^{Aff11, Aff12}, Darazam, Ilad Alavi^{Aff13, Aff14}, Allende, Luis M., Alonso-Arias, Rebeca, Arias, Andrés Augusto^{Aff3, Aff17, Aff18}, Aytekin, Gokhan, Bergman, Peter^{Aff20, Aff21}, Bondesan, Simone, Bryceson, Yenan T., Bustos, Ingrid G., Cabrera-Marante, Oscar, Carcel, Sheila, Carrera, Paola, Casari, Giorgio^{Aff27, Aff28}, Chaïbi, Khalil^{Aff29, Aff30}, Colobran, Roger^{Aff31, Aff32, Aff33}, Condino-Neto, Antonio, Covill, Laura E., Delmonte, Ottavia M., Zein, Loubna El, Flores, Carlos^{Aff36, Aff37, Aff38, Aff39}, Gregersen, Peter K., Gut, Marta, Haerynck, Filomeen, Halwani, Rabih, Hancerli, Selda, Hammarström, Lennart, Hatipoğlu, Nevin, Karbuz, Adem, Keles, Sevgi, Kyheng, Christèle, Leon-Lopez, Rafael, Franco, Jose Luis, Mansouri, Davood^{Aff50, Aff51, Aff52}, Martinez-Picado, Javier^{Aff53, Aff54, Aff55, Aff56, Aff57}, Akcan, Ozge Metin, Migeotte, Isabelle, Morange, Pierre-Emmanuel^{Aff59, Aff60}, Morelle, Guillaume, Martin-Nalda, Andrea^{Aff31, Aff61, Aff62}, Novelli, Giuseppe^{Aff63, Aff64}, Novelli, Antonio, Ozcelik, Tayfun, Palabiyik, Figen, Pan-Hammarström, Qiang, de Diego, Rebeca Pérez, Planas-Serra, Laura^{Aff68, Aff69}, Pleguezuelo, Daniel E., Prando, Carolina, Pujol, Aurora^{Aff56, Aff68, Aff69}, Reyes, Luis Felipe, Rivière, Jacques G.^{Aff31, Aff61, Aff62}, Rodriguez-Gallego, Carlos^{Aff72, Aff73}, Rojas, Julian, Rovere-Querini, Patrizia^{Aff12, Aff74}, Schlüter, Agatha^{Aff68, Aff69}, Shahrooei, Mohammad^{Aff75, Aff76}, Sobh, Ali, Soler-Palacin, Pere^{Aff31, Aff61, Aff62}, Tandjaoui-Lambiotte, Yacine, Tipu, Imran, Tresoldi, Cristina, Troya, Jesus, van de Beek, Diederik, Zatz, Mayana, Zawadzki, Pawel^{Aff84, Aff85}, Al-Muhsen, Saleh Zaid, Alosaimi, Mohammed Faraj, Alsohime, Fahad M., Baris-Feldman, Hagit^{Aff87, Aff88}, Butte, Manish J., Constantinescu, Stefan N.^{Aff90, Aff91, Aff92, Aff93}, Cooper, Megan A., Dalgard, Clifton L.^{Aff95, Aff96}, Fellay, Jacques^{Aff97, Aff98, Aff99}, Heath, James R., Lau, Yu-Lung, Lifton, Richard P.^{Aff102, Aff103, Aff104}, Maniatis, Tom^{Aff105, Aff106}, Mogensen, Trine H.^{Aff107, Aff108}, von Bernuth, Horst, Lermine, Alban, Vidaud, Michel, Boland, Anne, Deleuze, Jean-François, Nussbaum, Robert, Kahn-Kirby, Amanda, Mentre, France, Tubiana, Sarah, Gorochov, Guy, Tubach, Florence, Hausfater, Pierre^{Aff117, Aff118}, Meyts, Isabelle, Zhang, Shen-Ying^{Aff1, Aff2, Aff3}, Puel, Anne^{Aff1, Aff2, Aff3}, Notarangelo, Luigi D., Boisson-Dupuis, Stephanie^{Aff1, Aff2, Aff3}, Su, Helen C., Boisson, Bertrand^{Aff1, Aff2, Aff3}, Jouanguy, Emmanuelle^{Aff1, Aff2, Aff3}, Casanova, Jean-Laurent^{Aff1, Aff2, Aff3, Aff121, IDs13073023012780_cor126}, Zhang, Qian^{Aff1, Aff2, Aff3}, Abel, Laurent^{Aff1, Aff2, Aff3}, Cobat, Aurélie^{Aff1, Aff2, Aff3, IDs13073023012780_cor129}

المصدر: Genome Medicine. 16(1)

المؤلفون: Fava, Vinicius, Orlova, Marianna, Cobat, Aurélie, Alcaïs, Alexandre, Mira, Marcelo, Schurr, Erwin

المصدر: Memórias do Instituto Oswaldo Cruz. December 2012 107(1)

مصطلحات موضوعية: reversal reaction, type-1 leprosy reaction, erythema nodosum leprosum, type-2 leprosy reaction, host genetic background, leprosy

وصف الملف: text/html

URL الوصول: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762012000900020

المؤلفون: García-García, Ana, Pérez de Diego, Rebeca, Flores, Carlos, Rinchai, Darawan, Solé-Violán, Jordi, Deyà-Martínez, Àngela, García-Solis, Blanca, Lorenzo-Salazar, José, Hernández-Brito, Elisa, Lanz, Anna-Lisa, Moens, Leen, Bucciol, Giorgia, Almuqamam, Mohamed, Domachowske, Joseph, Colino, Elena, Santos-Perez, Juan, Marco, Francisco, Pignata, Claudio, Bousfiha, Aziz, Turvey, Stuart, Bauer, Stefanie, Haerynck, Filomeen, Ocejo-Vinyals, Javier, Lendinez, Francisco, Prader, Seraina, Naumann-Bartsch, Nora, Pachlopnik Schmid, Jana, Biggs, Catherine, Hildebrand, Kyla, Dreesman, Alexandra, Cárdenes, Miguel, Ailal, Fatima, Benhsaien, Ibtihal, Giardino, Giuliana, Molina-Fuentes, Agueda, Fortuny, Claudia, Madhavarapu, Swetha, Conway, Daniel, Prando, Carolina, Schidlowski, Laire, Martínez de Saavedra Álvarez, María, Alfaro, Rafael, Rodríguez de Castro, Felipe, Meyts, Isabelle, Hauck, Fabian, Puel, Anne, Bastard, Paul, Boisson, Bertrand, Jouanguy, Emmanuelle, Abel, Laurent, Cobat, Aurélie, Zhang, Qian, Casanova, Jean-Laurent, Alsina, Laia, Rodríguez-Gallego, Carlos

المصدر: Journal of Experimental Medicine. 220(5)

مصطلحات موضوعية: Child, Humans, Adaptor Proteins, Signal Transducing, COVID-19, Myeloid Differentiation Factor 88, SARS-CoV-2, Toll-Like Receptor 7

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0tw8q4qs
https://escholarship.org/content/qt0tw8q4qs/qt0tw8q4qs.pdf

المؤلفون: Le Voyer, Tom^{Aff1, Aff2, IDs4158602306717x_cor1}, Parent, Audrey V., Liu, Xian, Cederholm, Axel, Gervais, Adrian^{Aff1, Aff2}, Rosain, Jérémie^{Aff1, Aff2, Aff5}, Nguyen, Tina^{Aff6, Aff7}, Perez Lorenzo, Malena^{Aff1, Aff2}, Rackaityte, Elze, Rinchai, Darawan, Zhang, Peng, Bizien, Lucy^{Aff1, Aff2}, Hancioglu, Gonca, Ghillani-Dalbin, Pascale, Charuel, Jean-Luc, Philippot, Quentin^{Aff1, Aff2}, Gueye, Mame Sokhna^{Aff1, Aff2}, Maglorius Renkilaraj, Majistor Raj Luxman^{Aff1, Aff2}, Ogishi, Masato, Soudée, Camille^{Aff1, Aff2}, Migaud, Mélanie^{Aff1, Aff2}, Rozenberg, Flore, Momenilandi, Mana^{Aff1, Aff2}, Riller, Quentin, Imberti, Luisa, Delmonte, Ottavia M., Müller, Gabriele^{Aff16, Aff17}, Keller, Baerbel^{Aff17, Aff18}, Orrego, Julio, Franco Gallego, William Alexander, Rubin, Tamar, Emiroglu, Melike, Parvaneh, Nima, Eriksson, Daniel^{Aff23, Aff24, Aff25}, Aranda-Guillen, Maribel, Berrios, David I., Vong, Linda^{Aff26, Aff27}, Katelaris, Constance H., Mustillo, Peter, Raedler, Johannes, Bohlen, Jonathan^{Aff1, Aff2}, Bengi Celik, Jale, Astudillo, Camila^{Aff32, Aff33}, Winter, Sarah, McLean, Catriona, Guffroy, Aurélien, DeRisi, Joseph L.^{Aff8, Aff37}, Yu, David, Miller, Corey, Feng, Yi, Guichard, Audrey, Béziat, Vivien^{Aff1, Aff2, Aff9}, Bustamante, Jacinta^{Aff1, Aff2, Aff5, Aff9}, Pan-Hammarström, Qiang^{Aff39, Aff40}, Zhang, Yu^{Aff15, Aff41}, Rosen, Lindsey B., Holland, Steve M., Bosticardo, Marita, Kenney, Heather, Castagnoli, Riccardo^{Aff42, Aff43}, Slade, Charlotte A.^{Aff44, Aff45, Aff46}, Boztuğ, Kaan^{Aff47, Aff48, Aff49, Aff50}, Mahlaoui, Nizar^{Aff51, Aff52}, Latour, Sylvain, Abraham, Roshini S., Lougaris, Vassilios, Hauck, Fabian, Sediva, Anna, Atschekzei, Faranaz, Sogkas, Georgios, Poli, M. Cecilia^{Aff32, Aff33}, Slatter, Mary A., Palterer, Boaz, Keller, Michael D., Pinzon-Charry, Alberto^{Aff60, Aff61}, Sullivan, Anna^{Aff60, Aff61}, Droney, Luke^{Aff60, Aff61}, Suan, Daniel^{Aff60, Aff62}, Wong, Melanie^{Aff60, Aff62, Aff63}, Kane, Alisa^{Aff7, Aff60, Aff64, Aff65}, Hu, Hannah^{Aff60, Aff64, Aff65}, Ma, Cindy^{Aff6, Aff7, Aff60}, Grombiříková, Hana, Ciznar, Peter, Dalal, Ilan, Aladjidi, Nathalie, Hie, Miguel, Lazaro, Estibaliz, Franco, Jose, Keles, Sevgi, Malphettes, Marion, Pasquet, Marlene, Maccari, Maria Elena^{Aff16, Aff75}, Meinhardt, Andrea, Ikinciogullari, Aydan, Shahrooei, Mohammad^{Aff78, Aff79}, Celmeli, Fatih, Frosk, Patrick, Goodnow, Christopher C.^{Aff6, Aff7, Aff60}, Gray, Paul E.^{Aff60, Aff82}, Belot, Alexandre^{Aff83, Aff84, Aff85}, Kuehn, Hye Sun, Rosenzweig, Sergio D., Miyara, Makoto^{Aff11, Aff87}, Licciardi, Francesco, Servettaz, Amélie^{Aff89, Aff90}, Barlogis, Vincent, Le Guenno, Guillaume, Herrmann, Vera-Maria, Kuijpers, Taco, Ducoux, Grégoire, Sarrot-Reynauld, Françoise, Schuetz, Catharina, Cunningham-Rundles, Charlotte, Rieux-Laucat, Frédéric, Tangye, Stuart G.^{Aff6, Aff7, Aff60}, Sobacchi, Cristina^{Aff99, Aff100}, Doffinger, Rainer, Warnatz, Klaus^{Aff17, Aff18}, Grimbacher, Bodo^{Aff16, Aff17}, Fieschi, Claire^{Aff73, Aff102}, Berteloot, Laureline, Bryant, Vanessa L.^{Aff44, Aff45, Aff46}, Trouillet Assant, Sophie^{Aff38, Aff104}, Su, Helen^{Aff15, Aff41}, Neven, Benedicte, Abel, Laurent^{Aff1, Aff2, Aff9}, Zhang, Qian^{Aff1, Aff2, Aff9}, Boisson, Bertrand^{Aff1, Aff2, Aff9}, Cobat, Aurélie^{Aff1, Aff2, Aff9}, Jouanguy, Emmanuelle^{Aff1, Aff2, Aff9}, Kampe, Olle, Bastard, Paul^{Aff1, Aff2, Aff9, Aff52}, Roifman, Chaim M.^{Aff26, Aff27}, Landegren, Nils^{Aff4, Aff25}, Notarangelo, Luigi D., Anderson, Mark S.^{Aff3, Aff106}, Casanova, Jean-Laurent^{Aff1, Aff2, Aff9, Aff107, Aff108, IDs4158602306717x_cor140}, Puel, Anne^{Aff1, Aff2, Aff9, IDs4158602306717x_cor141}

المصدر: Nature: International weekly journal of science. 623(7988):803-813

المؤلفون: Mousavi Khorshidi, Mohadese Sadat, Seeleuthner, Yoann^{Aff2, Aff3}, Chavoshzadeh, Zahra, Behfar, Maryam^{Aff5, Aff6}, Hamidieh, Amir Ali^{Aff5, Aff6}, Alimadadi, Hosein, Sherkat, Roya, Momen, Tooba, Behniafard, Nasrin^{Aff10, Aff11}, Eskandarzadeh, Shabnam, Mansouri, Mahboubeh, Behnam, Mahdiyeh^{Aff13, Aff14}, Mahdavi, Mohadese, Heydarazad Zadeh, Maryam, Shokri, Mehdi, Alizadeh, Fatemeh, Movahedi, Mahshid, Momenilandi, Mana^{Aff2, Aff3}, Keramatipour, Mohammad, Casanova, Jean-Laurent^{Aff2, Aff3, Aff17}, Cobat, Aurélie^{Aff2, Aff3, Aff17}, Abel, Laurent^{Aff2, Aff3, Aff17}, Shahrooei, Mohammad^{Aff14, Aff18}, Parvaneh, Nima^{Aff1, Aff19, IDs1087502301562z_cor24}

المصدر: Journal of Clinical Immunology: International Journal of Inborn Errors of Immunity and Related Diseases. 43(8):1941-1952

المؤلفون: Philippot, Quentin^{Aff1, Aff2, IDs10875023015129_cor1}, Fekkar, Arnaud^{Aff1, Aff2, Aff3}, Gervais, Adrian^{Aff1, Aff2}, Le Voyer, Tom^{Aff1, Aff2}, Boers, Leonoor S., Conil, Clément^{Aff1, Aff2}, Bizien, Lucy^{Aff1, Aff2}, de Brabander, Justin, Duitman, Jan Willem^{Aff6, Aff7, Aff8}, Romano, Alessia^{Aff1, Aff2}, Rosain, Jérémie^{Aff1, Aff2}, Blaize, Marion, Migaud, Mélanie^{Aff1, Aff2}, Jeljeli, Maxime^{Aff9, Aff10}, Hammadi, Boualem, Desmons, Aurore, Marchal, Astrid^{Aff1, Aff2}, Mayaux, Julien^{Aff13, Aff14}, Zhang, Qian^{Aff1, Aff2, Aff15}, Jouanguy, Emmanuelle^{Aff1, Aff2, Aff15}, Borie, Raphael^{Aff16, Aff17}, Crestani, Bruno^{Aff16, Aff17}, Luyt, Charles Edouard^{Aff18, Aff19}, Adle-Biassette, Homa^{Aff20, Aff21}, Sene, Damien^{Aff22, Aff23}, Megarbane, Bruno^{Aff24, Aff25}, Cobat, Aurélie^{Aff1, Aff2, Aff15}, Bastard, Paul^{Aff1, Aff2, Aff15, Aff26}, Bos, Lieuwe D. J., Casanova, Jean-Laurent^{Aff1, Aff2, Aff15, Aff27, Aff28}, Puel, Anne^{Aff1, Aff2, Aff15}

المصدر: Journal of Clinical Immunology: International Journal of Inborn Errors of Immunity and Related Diseases. 43(6):1093-1103