المؤلفون: Maroeska J. Burggraaf, Alexander Speer, Aniek S. Meijers, Roy Ummels, Astrid M. van der Sar, Konstantin V. Korotkov, Wilbert Bitter, Coenraad Kuijl

المصدر: mBio, Vol 10, Iss 5 (2019)

مصطلحات موضوعية: aspartic protease, Mycobacterium, PE proteins, PE_PGRS, type VII secretion, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2150-7511

URL الوصول: https://doaj.org/article/471da19eeb16404ebd6a78080b66c8b0

المؤلفون: Jagath R. Junutula, Paul Polakis, Richard H. Scheller, Mark S. Dennis, Deepak Sampath, Jo-Anne Hongo, Helga Raab, Katherine R. Kozak, Aimee Fourie-O'Donohue, Ron Firestein, Robert Piskol, Eric Cheng, Mary Ann T. Go, Kirsten A. Poon, Fiona Zhong, Rachana Ohri, Coenraad Kuijl, Dongwei Li, Melissa M. Schutten, Meredith Hazen, Yvonne Chen, Lisa M. Crocker, Sunil Bhakta

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6ebbf88322d045b6d0c4b08c2c22021d
https://doi.org/10.1158/1535-7163.c.6537960.v1

المؤلفون: Jagath R. Junutula, Paul Polakis, Richard H. Scheller, Mark S. Dennis, Deepak Sampath, Jo-Anne Hongo, Helga Raab, Katherine R. Kozak, Aimee Fourie-O'Donohue, Ron Firestein, Robert Piskol, Eric Cheng, Mary Ann T. Go, Kirsten A. Poon, Fiona Zhong, Rachana Ohri, Coenraad Kuijl, Dongwei Li, Melissa M. Schutten, Meredith Hazen, Yvonne Chen, Lisa M. Crocker, Sunil Bhakta

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::100a6557ca8c0f2a229a1ced8e41d71e
https://doi.org/10.1158/1535-7163.22505118

المؤلفون: B. Izquierdo Lafuente, Alexander Speer, Roy Ummels, Wilbert Bitter, Coenraad Kuijl

المساهمون: VU University medical center, Medical Microbiology and Infection Prevention, AII - Infectious diseases, Molecular Microbiology, AIMMS

المصدر: Izquierdo Lafuente, B, Ummels, R, Kuijl, C, Bitter, W & Speer, A 2021, ' Mycobacterium tuberculosis toxin cpnt is an esx-5 substrate and requires three type vii secretion systems for intracellular secretion ', mBio, vol. 12, no. 2, e02983-20, pp. 1-16 . https://doi.org/10.1128/mBio.02983-20
mBio
mBio, 12(2):e02983-20, 1-16. American Society for Microbiology
mBio, Vol 12, Iss 2 (2021)

مصطلحات موضوعية: Virulence Factors, Bacterial Toxins, Mutant, Exotoxins, Microbiology, Host-Microbe Biology, Mycobacterium, Mycobacterium tuberculosis, Mice, Secretion systems, Bacterial Proteins, SDG 3 - Good Health and Well-being, Virology, Animals, Secretion, Cloning, Molecular, Pathogen, Secretory Pathway, biology, Chemistry, Effector, biology.organism_classification, QR1-502, RAW 264.7 Cells, Secretory protein, Type VII Secretion Systems, Mycobacterium marinum, Protein secretion, Intracellular, Bacterial Outer Membrane Proteins, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f97c2e9f345cfdb90b8d18db4dfd1569
https://doi.org/10.1128/mbio.02983-20

المؤلفون: Tom van Duivenvoorde, Lieve E. H. van der Donk, Louis S. Ates, Coenraad Kuijl, Jeroen W. J. van Heijst, Teunis B. H. Geijtenbeek, Marieke S. ten Brink, Jet van der Spek

مصطلحات موضوعية: Gene knockdown, Expression vector, In vivo, Promoter, Vector (molecular biology), Computational biology, Biology, Gene, In vitro, Insert (molecular biology)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::23b9999aab2e204b19234e0e9693155b
https://doi.org/10.1101/2021.01.08.425881

المؤلفون: Sergey Nejentsev, Aniek S. Meijers, Wilbert Bitter, J.J. Maaskant, Ran Troost, Coenraad Kuijl, Roy Ummels, Alexander Speer

المساهمون: Molecular Microbiology, AIMMS, Medical Microbiology and Infection Prevention, Molecular cell biology and Immunology, AII - Infectious diseases

المصدر: Tuberculosis, 124:101983. Churchill Livingstone
Meijers, A S, Troost, R, Ummels, R, Maaskant, J, Speer, A, Nejentsev, S, Bitter, W & Kuijl, C P 2020, ' Efficient genome editing in pathogenic mycobacteria using Streptococcus thermophilus CRISPR1-Cas9 ', Tuberculosis, vol. 124, 101983 . https://doi.org/10.1016/j.tube.2020.101983
Tuberculosis (Edinb)
Tuberculosis

مصطلحات موضوعية: 0301 basic medicine, Microbiology (medical), CRISPR-Cas9 system, Streptococcus thermophilus, 030106 microbiology, Immunology, Antitubercular Agents, Computational biology, medicine.disease_cause, Microbiology, Article, Mycobacterium tuberculosis, 03 medical and health sciences, Bacterial Proteins, INDEL Mutation, Genome editing, SDG 3 - Good Health and Well-being, CRISPR-Associated Protein 9, Drug Resistance, Bacterial, Isoniazid, medicine, CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, Mycobacterium marinum, Gene Editing, CRISPR interference, biology, Cas9, food and beverages, Gene Expression Regulation, Bacterial, Catalase, biology.organism_classification, 3. Good health, Indels, 030104 developmental biology, Infectious Diseases, Streptococcus pyogenes, CRISPR-Cas Systems, Gene Deletion, RNA, Guide, Kinetoplastida

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::674197def8b545024fb44356a834dde0
https://hdl.handle.net/1871.1/9838c9f5-a93a-4847-9414-ecb41492eed6

المؤلفون: James Lee, Benjamin L. Parker, Jacqueline Stöckli, David E. James, Eric Torres, Jean-Philippe Stephan, Jagath Reddy Junutula, Sophie Trefely, James R. Krycer, Coenraad Kuijl, Kenneth Jung, Poh Sim Khoo, Rima Chaudhuri, Daniel J. Fazakerley, Ghazal Sultani

المصدر: Journal of Biological Chemistry. 290:25834-25846

مصطلحات موضوعية: MAPK/ERK pathway, medicine.medical_specialty, Phosphofructokinase-2, Biology, Biochemistry, IGF-1 Signaling Pathway, Mice, 3T3-L1 Cells, Internal medicine, medicine, Animals, Humans, Insulin, Kinome, Insulin-Like Growth Factor I, RNA, Small Interfering, Molecular Biology, Protein kinase B, PI3K/AKT/mTOR pathway, Glucose Transporter Type 4, Kinase, Cell Biology, Cell biology, Glucose, Endocrinology, Phosphorylation, Signal transduction, Protein Kinases, HeLa Cells, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a346fdf7d2e97ad2bc200e56875a221b
https://doi.org/10.1074/jbc.m115.658815

المؤلفون: Sunil Bhakta, Lisa M. Crocker, Yvonne Chen, Meredith Hazen, Melissa M. Schutten, Dongwei Li, Coenraad Kuijl, Rachana Ohri, Fiona Zhong, Kirsten A. Poon, Mary Ann T. Go, Eric Cheng, Robert Piskol, Ron Firestein, Aimee Fourie-O'Donohue, Katherine R. Kozak, Helga Raab, Jo-Anne Hongo, Deepak Sampath, Mark S. Dennis, Richard H. Scheller, Paul Polakis, Jagath R. Junutula

المصدر: Molecular Cancer Therapeutics. 18:2182-2182

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9399149762155a1ed94b79a7dc92fdb
https://doi.org/10.1158/1535-7163.mct-19-0749

المؤلفون: Ron Firestein, Yvonne Chen, Rachana Ohri, Richard H. Scheller, Helga Raab, Katherine R. Kozak, Paul Polakis, Coenraad Kuijl, Dongwei Li, Meredith Hazen, Lisa Crocker, Robert Piskol, Mark S. Dennis, Jagath Reddy Junutula, Eric Cheng, Deepak Sampath, Kirsten Achilles Poon, Aimee Fourie-O'Donohue, Sunil Bhakta, Fiona Zhong, Melissa Schutten, Mary Ann T. Go, Jo-Anne Hongo

المساهمون: Medical Microbiology and Infection Prevention

المصدر: Bhakta, S, Crocker, L M, Chen, Y, Hazen, M, Schutten, M M, Li, D, Kuijl, C, Ohri, R, Zhong, F, Poon, K A, Go, M A T, Cheng, E, Piskol, R, Firestein, R, Fourie-O'Donohue, A, Kozak, K R, Raab, H, Hongo, J-A, Sampath, D, Dennis, M S, Scheller, R H, Polakis, P & Junutula, J R 2018, ' An anti-gdnf family receptor alpha 1 (gfra1 antibody–drug conjugate for the treatment of hormone receptor–positive breast cancer ', Molecular Cancer Therapeutics, vol. 17, no. 3, pp. 638-649 . https://doi.org/10.1158/1535-7163.MCT-17-0813
Molecular Cancer Therapeutics, 17(3), 638-649. American Association for Cancer Research Inc.

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Antibody-drug conjugate, Receptors, Steroid, Glial Cell Line-Derived Neurotrophic Factor Receptors, Immunoconjugates, Cell Survival, Mice, Nude, Antineoplastic Agents, Breast Neoplasms, Mice, SCID, Antibodies, Rats, Sprague-Dawley, 03 medical and health sciences, Breast cancer, In vivo, Cell Line, Tumor, Glial cell line-derived neurotrophic factor, Medicine, Animals, Humans, Receptor, biology, business.industry, Cancer, medicine.disease, Xenograft Model Antitumor Assays, Tumor Burden, body regions, Gene Expression Regulation, Neoplastic, Macaca fascicularis, 030104 developmental biology, HEK293 Cells, Oncology, Hormone receptor, Cancer research, biology.protein, MCF-7 Cells, Immunohistochemistry, Female, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76d4699f5d64f071d6e57818b2f7ff5b
https://pubmed.ncbi.nlm.nih.gov/31676543

المؤلفون: Jacques Neefjes, Hans Janssen, Monica Calero, Karen E. Ervin, Jagath Reddy Junutula, Sobhanaditya Jonnalagadda, Richard H. Scheller, Coenraad Kuijl, Manohar Pilli, Suresh K. Alahari, Poh-Sim Khoo

المصدر: The EMBO Journal. 32:713-727

مصطلحات موضوعية: Salmonella typhimurium, Endosome, Blotting, Western, RAC1, Endosomes, GTPase, Biology, Real-Time Polymerase Chain Reaction, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, Phosphatidylinositol Phosphates, Two-Hybrid System Techniques, Humans, Immunoprecipitation, RNA, Messenger, Molecular Biology, 030304 developmental biology, 0303 health sciences, General Immunology and Microbiology, Reverse Transcriptase Polymerase Chain Reaction, Effector, General Neuroscience, Intracellular parasite, Intracellular Signaling Peptides and Proteins, Biological Transport, rac GTP-Binding Proteins, Cell biology, Rac GTP-Binding Proteins, Protein Transport, rab GTP-Binding Proteins, Salmonella Infections, Vacuoles, Imidazoline Receptors, Guanosine Triphosphate, Rab, Lysosomes, 030217 neurology & neurosurgery, Intracellular, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::031824c2b9cebcd6635b5258133c373a
https://doi.org/10.1038/emboj.2013.10