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1
المؤلفون: Donglu Zhang, James Lee, Mark Merchant, Ted Lau, Maria Bagniewska, Michael R. Costa, Steffan Vartanian, Colin K. Watanabe, Honglin Chen, Sara A. Watson, David Stokoe, Scott E. Martin, Ryan J. Hartmaier, Trinna L. Cuellar, Florian Gnad, David Kan, Yuxin Liang, Benjamin Haley, Jenille Tan, Gabriele Schaefer, Christiaan Klijn, Liling Liu
المصدر: Cancer Research. 79:4828-4839
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Lung Neoplasms, Receptor, ErbB-3, NF-E2-Related Factor 2, Biology, digestive system, environment and public health, Receptor, IGF Type 1, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Growth factor receptor, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Animals, Humans, ERBB3, Cell Proliferation, Insulin-like growth factor 1 receptor, Gene knockdown, Kelch-Like ECH-Associated Protein 1, respiratory system, 030104 developmental biology, Oncology, chemistry, Cell culture, 030220 oncology & carcinogenesis, Mutation, Cancer research, Heterografts, Growth inhibition, Thioredoxin, Peroxiredoxin, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1796d7a0b2ed7d42f4ad1c58fa5a6b0b
https://doi.org/10.1158/0008-5472.can-18-2086 -
2
المؤلفون: Honglin Chen, Vasantharajan Janakiraman, Kim Newton, Sarah Kummerfield, Katherine E. Wickliffe, Julie Weng, Benjamin Haley, Michael R. Costa, Ben Chih, Colin K. Watanabe, Marinella Callow, Yuxin Liang, Russell Bainer, Trinna L. Cuellar
المصدر: Cell Death and Disease, Vol 9, Iss 3, Pp 1-13 (2018)
Cell Death & Diseaseمصطلحات موضوعية: 0301 basic medicine, Cancer Research, Necroptosis, Immunology, Biology, Article, Gene Expression Regulation, Enzymologic, Heterogeneous-Nuclear Ribonucleoproteins, Mice, 03 medical and health sciences, Cellular and Molecular Neuroscience, RIPK1, CRISPR-Associated Protein 9, Animals, Humans, CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, lcsh:QH573-671, Gene, Tissue homeostasis, Regulation of gene expression, lcsh:Cytology, Alternative splicing, Cell Biology, PTBP1, Fibroblasts, Cell biology, Alternative Splicing, HEK293 Cells, 030104 developmental biology, Receptor-Interacting Protein Serine-Threonine Kinases, Gene Targeting, CRISPR-Cas Systems, HT29 Cells, Polypyrimidine Tract-Binding Protein, Signal Transduction
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3
المؤلفون: Sarah K. Kummerfeld, Trinna L. Cuellar, Bettina L. Lee, Michael Reichelt, Benjamin Haley, Nobuhiko Kayagaki, Irma B. Stowe, Kathleen M. Mirrashidi, Colin K. Watanabe
المصدر: Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reportsمصطلحات موضوعية: 0301 basic medicine, Programmed cell death, Necrosis, Inflammasomes, lcsh:Medicine, Apoptosis, Caspase 8, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, NLRC4, medicine, Animals, Secretion, lcsh:Science, Mice, Knockout, Multidisciplinary, Genome, Chemistry, Macrophages, Calcium-Binding Proteins, Caspase 1, lcsh:R, Pyroptosis, Inflammasome, Cell biology, CARD Signaling Adaptor Proteins, Mice, Inbred C57BL, 030104 developmental biology, 030220 oncology & carcinogenesis, lcsh:Q, medicine.symptom, CRISPR-Cas Systems, Apoptosis Regulatory Proteins, medicine.drug
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4
المؤلفون: Anna-Maria Herzner, Tommy K. Cheung, Yogesh Goyal, Xiaotian Zhang, Jonas Doerr, David Arnott, Subhra Chaudhuri, Colin K. Watanabe, Trinna L. Cuellar, Steffen Durinck, Benjamin Haley, Jeremy Stinson, Brad A. Friedman, Zora Modrusan, Vasantharajan Janakiraman, Marie Classon
المصدر: Journal of Cell Biology. 216:3535-3549
مصطلحات موضوعية: 0301 basic medicine, Regulation of gene expression, Myeloid, Innate immune system, Myeloid leukemia, Cell Biology, Biology, medicine.disease, 03 medical and health sciences, Leukemia, 030104 developmental biology, medicine.anatomical_structure, Immune system, RNA interference, medicine, Cancer research, Gene silencing
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::44f0b570d560bbe714a11dfc2e089091
https://doi.org/10.1083/jcb.201612160 -
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المؤلفون: Colin K. Watanabe, Vasantharajan Janakiraman, Michael-Anne Sowick, Jinjie Li, Sobha R. Thamminana, Andrew Buechler, Maximilian Haeussler, Keith R. Anderson, Tuija M. Alcantar, Natasha O’Neil, Linda Ta, Søren Warming, Lucinda Tam, Lisa Lima, Merone Roose-Girma, Steffen Durinck, Jessica Lund, Jeremy Stinson, Charles Yu, Zora Modrusan, Qixin Bei, Xin Y. Rairdan
المصدر: Nature methods, vol 15, iss 7
مصطلحات موضوعية: Male, 0301 basic medicine, Technology, Mutation rate, Genomics, Biology, Medical and Health Sciences, Biochemistry, Genome, Article, Cell Line, Mice, 03 medical and health sciences, 0302 clinical medicine, Genetics, Animals, CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, Guide RNA, Molecular Biology, Whole genome sequencing, Whole Genome Sequencing, Cas9, Human Genome, RNA, Cell Biology, Biological Sciences, Rats, Good Health and Well Being, 030104 developmental biology, 030220 oncology & carcinogenesis, Female, Genetic Engineering, Multiplex Polymerase Chain Reaction, Developmental Biology, Biotechnology
وصف الملف: application/pdf
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6
المؤلفون: Christopher C. Goodnow, Zora Modrusan, Irma B. Stowe, Rohit Reja, Bettina L. Lee, Sarah K. Kummerfeld, T. Daniel Andrews, Vishva M. Dixit, Benjamin Haley, Karen O'Rourke, Lucy X. Morris, Edward M. Bertram, Kathleen M. Mirrashidi, Yafei Zhang, Merone Roose-Girma, Nobuhiko Kayagaki, Vicky Cho, Colin K. Watanabe, Opher S. Kornfeld
المصدر: Science Signaling. 12
مصطلحات موضوعية: 0303 health sciences, Modern medicine, Chemistry, Pyroptosis, Inflammasome, Cell Biology, Biochemistry, Cell biology, 03 medical and health sciences, 0302 clinical medicine, Mediator, Transcription (biology), 030220 oncology & carcinogenesis, medicine, Secretion, Molecular Biology, Transcription factor, 030304 developmental biology, medicine.drug, Interferon regulatory factors
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c7bfcff7b8e203f4b150307103553171
https://doi.org/10.1126/scisignal.aax4917 -
7
المؤلفون: Benjamin Haley, Vivek S. Chopra, Edward Lorenzana, Ehud Segal, Mark McCleland, Murat Yaylaoglu, Colin K. Watanabe, Florian Gnad, Kathryn Mesh, Ron Firestein, Oleg Mayba
المصدر: Journal of Clinical Investigation. 126:639-652
مصطلحات موضوعية: 0301 basic medicine, BRD4, Mice, Nude, Cell Cycle Proteins, Biology, Proto-Oncogene Proteins c-myc, BET inhibitor, Mice, 03 medical and health sciences, Transcription (biology), Cell Line, Tumor, Biomarkers, Tumor, Animals, Humans, RNA, Neoplasm, Epigenetics, Enhancer, Transcription factor, Cell Proliferation, Nuclear Proteins, Azepines, DNA, Neoplasm, General Medicine, DNA Methylation, Triazoles, Molecular biology, digestive system diseases, Bromodomain, 030104 developmental biology, Gene Knockdown Techniques, DNA methylation, Cancer research, CpG Islands, Female, RNA, Long Noncoding, Colorectal Neoplasms, Research Article, Transcription Factors
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المؤلفون: Colin K. Watanabe, Trinna L. Cuellar, Benjamin Haley
المصدر: RNA Biology
مصطلحات موضوعية: 0301 basic medicine, Small RNA, Small interfering RNA, Genetic Vectors, Context (language use), Computational biology, Biology, Small hairpin RNA, Mice, 03 medical and health sciences, shRNA, RNA interference, Animals, Humans, Gene silencing, Guide RNA, RNA, Small Interfering, Molecular Biology, miRNA, RNA, Double-Stranded, Genetics, Technical Paper, RNA Polymerase III, Cell Biology, MicroRNAs, HEK293 Cells, 030104 developmental biology, RNAi, siRNA, RNA Interference, RNA Polymerase II, Expression cassette, Algorithms, amiRNA
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9
المؤلفون: Nicholas Dompe, David Stokoe, Katherine R. Welker Leng, Trinna L. Cuellar, Marie Evangelista, Sara A. Watson, Benjamin Haley, Christiaan Klijn, Colin K. Watanabe, Richard M. Neve, Jenna Port
المصدر: PLoS ONE
PLoS ONE, Vol 13, Iss 6, p e0199264 (2018)مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Genetic Screens, Cell signaling, Mutant, MAPK7, Cancer Treatment, Gene Identification and Analysis, lcsh:Medicine, Signal transduction, ERK signaling cascade, medicine.disease_cause, Synthetic Genome Editing, Genome Engineering, Lung and Intrathoracic Tumors, chemistry.chemical_compound, Mice, Genomic Library Screening, Carcinoma, Non-Small-Cell Lung, Medicine and Health Sciences, Clustered Regularly Interspaced Short Palindromic Repeats, lcsh:Science, Gene knockdown, Multidisciplinary, MEK inhibitor, Crispr, Signaling cascades, Oncology, Engineering and Technology, Synthetic Biology, KRAS, Research Article, Biotechnology, Cell biology, MAPK signaling cascades, MAP Kinase Signaling System, Bioengineering, Library Screening, Biology, Research and Analysis Methods, Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, medicine, Genetics, Biomarkers, Tumor, Animals, Humans, Molecular Biology Techniques, neoplasms, Molecular Biology, Mitogen-Activated Protein Kinase 7, Cobimetinib, Molecular Biology Assays and Analysis Techniques, lcsh:R, Biology and Life Sciences, Cancers and Neoplasms, Synthetic Genomics, Xenograft Model Antitumor Assays, respiratory tract diseases, Non-Small Cell Lung Cancer, 030104 developmental biology, chemistry, Synthetic Bioengineering, A549 Cells, Cancer research, lcsh:Q, Genetic screen
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المؤلفون: Scott E. Martin, Richard Bourgon, Christiaan Klijn, Oleg Mayba, Michael R. Costa, Colin K. Watanabe, Siyu Feng, Bob Yauch, Russell Bainer, Eva Lin, Catherine Wilson, Marinella Callow
المصدر: Cancer Research. 78:398-398
مصطلحات موضوعية: Cancer Research, Oncology, Computational biology, Drug resistance, Biology, Coding (social sciences)
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::db43f7d33e1c32c801f2998def5b08ae
https://doi.org/10.1158/1538-7445.am2018-398