المؤلفون: Liu X; State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. Electronic address: 125796660@qq.com., Mao X; State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. Electronic address: xmao@icmm.ac.cn., Chen W; State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. Electronic address: chenwenjia@63.com., Zhang Y; State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. Electronic address: dr_zhangyi@126.com., Li T; State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. Electronic address: qd_litao1218@126.com., Wang K; State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. Electronic address: 15584372132@163.com., Lin N; State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. Electronic address: nlin@icmm.ac.cn., Zhang Y; State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. Electronic address: yqzhang@icmm.ac.cn.

المصدر: International immunopharmacology [Int Immunopharmacol] 2024 Sep 10; Vol. 138, pp. 112573. Date of Electronic Publication: 2024 Jul 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Arthritis, Rheumatoid*/drug therapy , Arthritis, Experimental*/drug therapy , Drugs, Chinese Herbal*/therapeutic use , Drugs, Chinese Herbal*/pharmacology , Collagen Type I, alpha 1 Chain* , Collagen Type I*/metabolism , Collagen Type I*/genetics, Animals ; Rats ; Humans ; Male ; Gene Regulatory Networks/drug effects ; Core Binding Factor Alpha 1 Subunit/genetics ; Core Binding Factor Alpha 1 Subunit/metabolism ; Cartilage/metabolism ; Cartilage/pathology ; Cartilage/drug effects ; Bone and Bones/drug effects ; Bone and Bones/metabolism ; Bone and Bones/pathology ; Anti-Inflammatory Agents/therapeutic use ; Anti-Inflammatory Agents/pharmacology ; Signal Transduction/drug effects

عنوان ترانسليتريتد: Vererbte Varianten in den Genen COL11A, COL1A, COL5A1, COMP, GSTM1 und das Risiko eines Karpaltunnelsyndroms.

المؤلفون: Zyluk A; Department of General and Hand Surgery, Pomeranian Medical University, Szczecin, Poland., Debniak T; Department of Genetics and Pathomorfology, Pomeranian Medical University, Szczecin, Poland., Flicinski F; Department of General and Hand Surgery, Pomeranian Medical University, Szczecin, Poland., Rudnicka H; Department of Genetics and Pathomorfology, Pomeranian Medical University, Szczecin, Poland.

المصدر: Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V.. [Handchir Mikrochir Plast Chir] 2024 Sep; Vol. 56 (5), pp. 359-367. Date of Electronic Publication: 2024 Sep 27.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Hippokrates Verlag Country of Publication: Germany NLM ID: 8302815 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-3980 (Electronic) Linking ISSN: 07221819 NLM ISO Abbreviation: Handchir Mikrochir Plast Chir Subsets: MEDLINE

مواضيع طبية MeSH: Carpal Tunnel Syndrome*/genetics , Collagen Type I*/genetics , Collagen Type XI*/genetics , Genetic Predisposition to Disease* , Collagen Type V*/genetics , Glutathione Transferase*/genetics , Collagen Type I, alpha 1 Chain*/genetics, Humans ; Female ; Male ; Middle Aged ; Adult ; Genotype ; Aged ; High-Throughput Nucleotide Sequencing

المؤلفون: Dalgleish R; Department of Genetics and Genome Biology, University of Leicester, University Road, Leicester, LE1 7RH, UK. raymond.dalgleish@leicester.ac.uk.

المصدر: Human cell [Hum Cell] 2024 Sep; Vol. 37 (5), pp. 1610-1611. Date of Electronic Publication: 2024 Jun 15.

نوع المنشور: Letter; Comment

بيانات الدورية: Publisher: Springer Country of Publication: Japan NLM ID: 8912329 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1749-0774 (Electronic) Linking ISSN: 09147470 NLM ISO Abbreviation: Hum Cell Subsets: MEDLINE

مواضيع طبية MeSH: Induced Pluripotent Stem Cells* , CRISPR-Cas Systems*/genetics , Mutation*/genetics , Collagen Type I, alpha 1 Chain* , Collagen Type I*/genetics , Collagen Type I*/metabolism, Humans ; Cell Line

المؤلفون: Xiao Y; Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, No. 107 Yanjiang West Road, Guangzhou, Guangdong, 510000, China.; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, 510000, China., Lai C; Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, No. 107 Yanjiang West Road, Guangzhou, Guangdong, 510000, China.; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, 510000, China., Hu J; Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, No. 107 Yanjiang West Road, Guangzhou, Guangdong, 510000, China.; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, 510000, China., Mulati Y; Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, No. 107 Yanjiang West Road, Guangzhou, Guangdong, 510000, China.; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, 510000, China., Xu X; Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, No. 107 Yanjiang West Road, Guangzhou, Guangdong, 510000, China.; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, 510000, China., Luo J; Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, No. 107 Yanjiang West Road, Guangzhou, Guangdong, 510000, China.; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, 510000, China., Kong D; Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, No. 107 Yanjiang West Road, Guangzhou, Guangdong, 510000, China.; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, 510000, China., Liu C; Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, No. 107 Yanjiang West Road, Guangzhou, Guangdong, 510000, China. liuch278@mail.sysu.edu.cn.; Guangdong Provincial Clinical Research Center for Urological Diseases, Guangzhou, Guangdong, 510000, China. liuch278@mail.sysu.edu.cn., Xu K; Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, No. 107 Yanjiang West Road, Guangzhou, Guangdong, 510000, China. xukewei@mail.sysu.edu.cn.; Guangdong Provincial Clinical Research Center for Urological Diseases, Guangzhou, Guangdong, 510000, China. xukewei@mail.sysu.edu.cn.; Sun Yat-sen University School of Medicine, Sun Yat-sen University, Shenzhen, Guangdong, 518000, China. xukewei@mail.sysu.edu.cn.

المصدر: BMC cancer [BMC Cancer] 2024 Aug 22; Vol. 24 (1), pp. 1038. Date of Electronic Publication: 2024 Aug 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407 (Electronic) Linking ISSN: 14712407 NLM ISO Abbreviation: BMC Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Prostatic Neoplasms*/genetics , Prostatic Neoplasms*/pathology , Prostatic Neoplasms*/metabolism , Prostatic Neoplasms*/mortality , Collagen Type I, alpha 1 Chain* , Nomograms* , Collagen Type I*/genetics , Collagen Type I*/metabolism , Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase*/genetics , Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase*/metabolism, Humans ; Male ; Prognosis ; Matrix Metalloproteinase 11/genetics ; Matrix Metalloproteinase 11/metabolism ; Gene Expression Regulation, Neoplastic ; Cell Line, Tumor ; Collagen/metabolism ; Collagen/genetics ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Tumor Microenvironment/genetics ; Aged ; Cell Proliferation/genetics ; Cell Movement/genetics

المؤلفون: Pan H; School of Food and Biological Engineering, Jiangsu University, Zhenjiang, China.; The Affiliated People's Hospital of Jiangsu University, Zhenjiang, China., Hong J; The Affiliated People's Hospital of Jiangsu University, Zhenjiang, China., Shao A; The Affiliated People's Hospital of Jiangsu University, Zhenjiang, China., Zhao Z; The Affiliated People's Hospital of Jiangsu University, Zhenjiang, China., Ding G; The Affiliated People's Hospital of Jiangsu University, Zhenjiang, China., Fang Z; Department of Otolaryngology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzou, China., Chen K; School of Food and Biological Engineering, Jiangsu University, Zhenjiang, China., Zhu J; The Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.

المصدر: The clinical respiratory journal [Clin Respir J] 2024 Jul; Vol. 18 (7), pp. e13793.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Blackwell Publishing Country of Publication: England NLM ID: 101315570 Publication Model: Print Cited Medium: Internet ISSN: 1752-699X (Electronic) Linking ISSN: 17526981 NLM ISO Abbreviation: Clin Respir J Subsets: MEDLINE

مواضيع طبية MeSH: Esophageal Neoplasms*/genetics , Esophageal Neoplasms*/pathology , Esophageal Neoplasms*/metabolism , Biomarkers, Tumor*/genetics , Biomarkers, Tumor*/metabolism , Collagen Type I, alpha 1 Chain* , Keratin-17*/genetics , Keratin-17*/metabolism , Esophageal Squamous Cell Carcinoma*/genetics , Esophageal Squamous Cell Carcinoma*/metabolism, Humans ; Male ; Female ; Middle Aged ; Collagen Type I/genetics ; Collagen Type I/metabolism ; Aged ; Gene Expression Regulation, Neoplastic

المؤلفون: Xie X; Department of Vascular Surgery, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, Fujian 361015, China., Yuan Y; Department of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China.; Vascular Surgery Institute of Fudan University, Fudan University, Shanghai 200032, China., Huang Y; Department of Vascular Surgery, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, Fujian 361015, China., Hong X; Department of Vascular Surgery, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, Fujian 361015, China., Hong S; Department of Vascular Surgery, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, Fujian 361015, China., Chen G; Department of Vascular Surgery, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, Fujian 361015, China., Chen Y; Department of Vascular Surgery, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, Fujian 361015, China., Lin Y; Department of Vascular Surgery, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, Fujian 361015, China., Lu W; Department of Vascular Surgery, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, Fujian 361015, China., Fu W; Department of Vascular Surgery, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, Fujian 361015, China.; Department of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China.; Vascular Surgery Institute of Fudan University, Fudan University, Shanghai 200032, China., Wang L; Department of Vascular Surgery, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, Fujian 361015, China.; Department of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China.; Vascular Surgery Institute of Fudan University, Fudan University, Shanghai 200032, China.

المصدر: Chinese medical journal [Chin Med J (Engl)] 2024 May 05; Vol. 137 (9), pp. 1105-1114. Date of Electronic Publication: 2023 Aug 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Chinese Medical Association ; produced by Wolters Kluwer Country of Publication: China NLM ID: 7513795 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2542-5641 (Electronic) Linking ISSN: 03666999 NLM ISO Abbreviation: Chin Med J (Engl) Subsets: MEDLINE

مواضيع طبية MeSH: Aortic Aneurysm, Thoracic*/genetics , Aortic Aneurysm, Thoracic*/metabolism , Aortic Aneurysm, Thoracic*/pathology , Collagen Type I, alpha 1 Chain*/metabolism , Collagen Type I, alpha 1 Chain*/genetics , Collagen Type I*/genetics , Collagen Type I*/metabolism , Extracellular Matrix*/metabolism , Extracellular Matrix*/genetics, Humans ; Inflammation/genetics ; Inflammation/metabolism

المؤلفون: Zhou G; Department of Cardiology, Shunde Hospital of Guangzhou University of Chinese Medicine, Foshan, China; First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China., Lin Z; First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China., Miao Q; First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China., Lin L; First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China., Wang S; First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China., Lu K; First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China., Zhang Y; First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China., Chu Q; First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China; Cardiology Center, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China; Guangdong Clinical Research Academy of Chinese Medicine, Guangzhou, China., Kong W; Department of Cardiology, Shunde Hospital of Guangzhou University of Chinese Medicine, Foshan, China., Wu K; Department of Cardiology, Shunde Hospital of Guangzhou University of Chinese Medicine, Foshan, China., Liu P; Department of Cardiology, Shunde Hospital of Guangzhou University of Chinese Medicine, Foshan, China., Wu W; First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China; Cardiology Center, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China. Electronic address: zywuwei@163.com., Peng R; Department of Cardiology, Shunde Hospital of Guangzhou University of Chinese Medicine, Foshan, China; First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China; Guangdong Clinical Research Academy of Chinese Medicine, Guangzhou, China. Electronic address: gzucm1981@163.com., Luo C; First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China; Cardiology Center, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China; Guangdong Clinical Research Academy of Chinese Medicine, Guangzhou, China. Electronic address: gztcm1964@163.com.

المصدر: International immunopharmacology [Int Immunopharmacol] 2024 Nov 15; Vol. 141, pp. 112890. Date of Electronic Publication: 2024 Aug 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Drugs, Chinese Herbal*/therapeutic use , Drugs, Chinese Herbal*/pharmacology , Drugs, Chinese Herbal*/chemistry , Atherosclerosis*/drug therapy , Atherosclerosis*/genetics , Computational Biology*/methods , Machine Learning* , Molecular Docking Simulation* , Collagen Type I, alpha 1 Chain*, Animals ; Mice ; Humans ; Male ; Collagen Type I/genetics ; Collagen Type I/metabolism ; Mice, Inbred C57BL ; Disease Models, Animal ; Gene Expression Profiling ; Plaque, Atherosclerotic/drug therapy

المؤلفون: Li HY; Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China; The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China., Xu XY; Affiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China., Lv SH; Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China., Chen W; Affiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China., Wang Y; Affiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China., Fu Y; Affiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China., Yang JP; Affiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China. Electronic address: yyfyjp0507@126.com.

المصدر: Cellular signalling [Cell Signal] 2024 Nov; Vol. 123, pp. 111373. Date of Electronic Publication: 2024 Aug 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 8904683 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3913 (Electronic) Linking ISSN: 08986568 NLM ISO Abbreviation: Cell Signal Subsets: MEDLINE

مواضيع طبية MeSH: RNA, Long Noncoding*/genetics , RNA, Long Noncoding*/metabolism , Fibrosis* , MicroRNAs*/metabolism , MicroRNAs*/genetics , Collagen Type I, alpha 1 Chain*/metabolism , Receptor, Transforming Growth Factor-beta Type I*/metabolism , Receptor, Transforming Growth Factor-beta Type I*/genetics , Collagen Type I*/metabolism , Rats, Sprague-Dawley*, Animals ; Humans ; Rats ; Male ; Transforming Growth Factor beta1/metabolism ; Cell Line ; Kidney/pathology ; Kidney/metabolism ; Signal Transduction

المؤلفون: Gulucu S; Department of Gynecology and Obstetrics, Faculty of Medicine, Tokat Gaziosmanpasa University, Tokat, Turkey., Onal M; Department of Gynecology and Obstetrics, Faculty of Medicine, Ondokuz Mayis University, Tokat, Turkey., Karakus N; Department of Medical Biology, Faculty of Medicine, Tokat Gaziosmanpasa University, Tokat, Turkey. nevinbalci@hotmail.com.

المصدر: Reproductive sciences (Thousand Oaks, Calif.) [Reprod Sci] 2024 Oct; Vol. 31 (10), pp. 3058-3065. Date of Electronic Publication: 2024 Aug 29.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Country of Publication: United States NLM ID: 101291249 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1933-7205 (Electronic) Linking ISSN: 19337191 NLM ISO Abbreviation: Reprod Sci Subsets: MEDLINE

مواضيع طبية MeSH: Uterine Cervical Incompetence*/genetics , Transforming Growth Factor beta1*/genetics , Collagen Type I, alpha 1 Chain*/genetics , Genetic Predisposition to Disease* , Collagen Type I*/genetics , Polymorphism, Single Nucleotide* , Promoter Regions, Genetic*, Humans ; Female ; Adult ; Gene Frequency ; Case-Control Studies ; Genotype

المؤلفون: Mihara T; Department of Veterinary Pharmacology, Graduate School of Agriculture and Life Sciences, The University of Tokyo, Tokyo, Japan., Hori M

المصدر: Hepatology communications [Hepatol Commun] 2024 Jun 05; Vol. 8 (6). Date of Electronic Publication: 2024 Jun 05 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 101695860 Publication Model: eCollection Cited Medium: Internet ISSN: 2471-254X (Electronic) Linking ISSN: 2471254X NLM ISO Abbreviation: Hepatol Commun Subsets: MEDLINE

مواضيع طبية MeSH: alpha7 Nicotinic Acetylcholine Receptor*/metabolism , alpha7 Nicotinic Acetylcholine Receptor*/genetics , Hepatic Stellate Cells*/metabolism , Hepatic Stellate Cells*/drug effects , Nicotine*/adverse effects , Liver Cirrhosis*/chemically induced , Liver Cirrhosis*/metabolism , Liver Cirrhosis*/pathology , Collagen Type I*/metabolism , Collagen Type I, alpha 1 Chain*/metabolism , Carbon Tetrachloride*, Animals ; Mice ; Humans ; Rats ; Male ; Cell Proliferation/drug effects ; Aconitine/pharmacology ; Aconitine/analogs & derivatives ; Cell Line ; Mice, Inbred C57BL ; Transforming Growth Factor beta1/metabolism ; Mice, Knockout ; Nicotinic Agonists/pharmacology